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Best Large Grants for Nonprofit Organizations in District of Columbia

Find the perfect Large Grants for Nonprofit Organizations in District of Columbia on Instrumentl. 9,000+ Large Grants for Nonprofit Organizations in District of Columbia in the United States.

9,000+

Available grants

$2.61B

Total funding

$5K

Median grant

9,000+ grants
$2.61B total
$5K median

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9,297 Results based on applied filters

San Diego Foundation: Athena Scholarship

The San Diego Foundation
Private
United States
US $1,000 - US $5,000

About Us

We enable donors and nonprofit partners to tackle the most critical needs facing San Diegans.

Mission & Values

Our vision is for just, equitable and resilient communities.

Our mission is to inspire enduring philanthropy and enable community solutions to improve the quality of life in our region.

We value all people, all partners and our region.

Common Scholarship Application

Achieve your Higher Education Dreams

In just one application, our Common Scholarship Application provides students access to more than 150 scholarship opportunities with awards ranging from $1,000 to more than $5,000.

In 2025, San Diego Foundation awarded a record-breaking $5.5 million in scholarships to nearly 1,400 students.

Educational Access & Equity Women & Girl Services STEM / STEAM Education +1 more

Lillian Gorell Scholarship Fund

Pittsburgh Foundation
Private
United States
Unspecified amount
The Lillian Gorell Scholarship Fund, established by the Pittsburgh Foundation, offers financial support to deserving students, particularly benefiting blind students and those pursuing studies in the arts. Founded in 1945, the Pittsburgh Foundation emphasizes community stewardship and long-term impact through its philanthropic efforts. This scholarship aims to empower students to achieve their educational goals while enhancing the quality of life in southwestern Pennsylvania.
Education - Higher Education Career / College Preparation College Success / Persistence

Richard H. and Ann M. Gerken Scholarship

Community Foundation of the Lowcountry
Private
United States
Unspecified amount
The Richard H. and Ann M. Gerken Scholarship, established in 2013 by the Community Foundation of the Lowcountry, aims to support qualified students pursuing post-secondary education in nursing or medicine. Eligible applicants must be residents of Hilton Head Island, graduating from a local high school with a minimum GPA of 3.0. This scholarship reflects the foundation's commitment to enriching the lives of Lowcountry citizens through education and healthcare.
Education - Higher Education Nursing Career / College Preparation

Intervention Research to Improve Native American Health (R34 Clinical Trial Optional)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Up to US $450,000
This funding opportunity supports research aimed at improving health among Native American populations by developing, adapting, and testing interventions. It addresses significant health disparities and seeks culturally informed solutions. The initiative encourages research that informs intervention strategies tailored to community needs, focusing on sustainability and scalability. The program is vital for enhancing health equity and resilience in Native American communities, ultimately aiming to reduce morbidity and mortality through effective health interventions.
Health Disparities & Social Determinants of Health Native American Services Indigenous Health Systems

Intervention Research to Improve Native American Health (R01 Clinical Trial Optional) (350160)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Up to US $2,500,000
This funding opportunity announcement aims to enhance health interventions for Native American populations. It supports research to develop, adapt, and test culturally informed health promotion and disease prevention strategies. The initiative addresses significant health disparities faced by these communities, emphasizing sustainable and adaptable solutions. Researchers are encouraged to build on community strengths and resilience, focusing on effective dissemination and integration of interventions. The program welcomes applications targeting diverse Native American groups, including Alaska Natives and Native Hawaiians.
Health Disparities & Social Determinants of Health Native American Services Indigenous Health Systems

Intervention Research to Improve Native American Health (R21 Clinical Trials Optional)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Up to US $275,000
The Intervention Research to Improve Native American Health (R21 Clinical Trials Optional) aims to support exploratory studies focused on enhancing health outcomes within Native American populations. This initiative encourages research that addresses critical health disparities, tests new interventions, and develops culturally appropriate solutions to improve health and well-being. Applications are encouraged to include community-driven research, addressing unique sociopolitical and environmental challenges faced by these populations, ultimately aiming to reduce morbidity and mortality.
Native American Services Indigenous Health Systems Health Disparities & Social Determinants of Health

40 & 8 Veterans Scholarships

Minnesota Nurses Association Foundation (MNAF)
Association/Society
United States
Up to US $2,000

About MNA

The Minnesota Nurses Association (MNA) stands strong for nurses, patients, and quality healthcare everywhere.

We are 22,000 dedicated RNs and other healthcare professionals in Minnesota, Wisconsin, North Dakota, and Iowa, who promote the professional, economic, and personal well-being of nurses through collective action. Our members care for patients in hospitals, clinics, nursing homes, and other healthcare settings.

Since 1905, MNA members have effectively influenced healthcare policy and practice; advocating for social justice and public health, as well as nursing practice and policies that enable nurses to provide the quality care patients deserve.

MNA empowers members to use their collective strength, knowledge, and experience to advance and enhance safe and professional nursing practice, nursing leadership, and community health and well-being, including access to quality healthcare for all.

MNA Foundation Scholarships & Grants

The Minnesota Nurses Association Foundation (MNAF), a non-profit corporation affiliated with the Minnesota Nurses Association, awards scholarships and grants each year to advance the nursing profession and create more opportunities for students to achieve their goals. 

MNA members, members’ dependents and grandchildren, nursing students, and veterans are eligible to apply for MNA Foundation Scholarships.  

40 & 8 Veterans Scholarships

Education - Higher Education Nursing Academic Scholarship Programs +1 more

Marc Chary Scholarship Program

Community Foundation of the Lowcountry
Private
United States
Unspecified amount
The Marc Chary Scholarship Program, established in 2025 by Mr. Marc Chary, aims to support African American high school seniors from Southern Beaufort and Jasper Counties in South Carolina. This scholarship is focused on those with financial need pursuing post-secondary education. With a commitment to enhancing educational opportunities, the Community Foundation of the Lowcountry continues to empower students to achieve their academic goals, fostering a thriving community through dedicated philanthropic efforts.
Education - Higher Education Career / College Preparation Black American Services

Toward An Inclusive Architecture Scholarship Fund

Community Foundation of Middle Tennessee
Private
United States
Unspecified amount
The Toward An Inclusive Architecture Scholarship Fund, managed by the Community Foundation of Middle Tennessee, aims to empower Tennesseans of color by providing financial support for architectural education. This initiative not only covers educational expenses at accredited architecture schools but also enhances professional growth through internship placements at partner firms. By fostering diversity in architecture, the scholarship seeks to create a more inclusive and thriving community in Tennessee.
Education - Higher Education Academic Scholarship Programs Minority Services +1 more

John Edelman Scholarship

Student Veterans of America
Private
United States
US $10,000
The John Edelman Scholarship supports student veterans pursuing careers in mental health counseling, offering five scholarships of $10,000 each. This initiative, funded by Student Veterans of America, emphasizes the importance of mental health support for veterans. Eligible candidates must be enrolled as full-time students in the 2025-2026 academic year and maintain strong academic performance. The scholarship aims to reward exceptional achievement and encourage further study in disciplines that promote mental well-being.
Military & Veterans Services Mental Health & Psychiatric Diseases Psychology

Tribal Self-Governance - Negotiation

Indian Health Service
Federal Government
United States
Unspecified amount
The Tribal Self-Governance Planning and Negotiation Cooperative Agreements are designed to assist tribes in planning and preparing to manage healthcare services for their members through the Tribal Self Governance Program. The Indian Health Service will provide three awards under this initiative, aiming to empower tribal organizations in their efforts to enhance healthcare delivery and self-determination.
Native American Services Indigenous Sovereignty & Rights Indigenous Services

South Carolina Arms Collectors Association Scholarship

Central Carolina Community Foundation
Private
United States
Unspecified amount

About

Central Carolina Community Foundation is a nonprofit organization that helps generous people give back to the Midlands of South Carolina in ways that matter. Since 1984, we’ve been a trusted partner, helping individuals, families, and businesses make smart, meaningful contributions that support local nonprofits, scholarships, and community projects.

South Carolina Arms Collectors Association Scholarship ($2,000)

This renewable scholarship is for members, dependents or grandchildren of members of the South Carolina Arms Collectors Association in good standing for the last three consecutive years. 

Education - Higher Education Education - High School Academic Scholarship Programs +1 more

Chrysalis Fund

Entomological Society of America (ESA)
Association/Society
United States
Up to US $2,500
The Chrysalis Fund, managed by the Entomological Society of America, supports K-12 educators in fostering youth interest in insect science. Grants can cover various project expenses, including supplies and travel costs. Funding levels include micro-grants (under $500), regular grants ($500-$999), and large grants ($1,000-$2,500). This initiative encourages innovative educational programs that engage students with entomology, enhancing their learning experience and promoting science education.
Entomology Education - K through 12

Kenneth P. Rutter (Rotary) Scholarship Fund

Pittsburgh Foundation
Private
United States
US $2,500

The Pittsburgh Foundation provides scholarship opportunities for students to pursue their educational goals. Scholarships are available for graduating high school seniors, undergraduates, graduate, medical and professional school students who are attending community colleges, four–year universities, graduate schools, and career/technical schools.

Kenneth P. Rutter (Rotary) Scholarship Fund

The Kenneth P. Rutter Scholarship Fund was established at The Community Foundation of Westmoreland County to award a scholarship to a traditional or non-traditional applicant residing in Westmoreland County, who has achieved a high school diploma or equivalent including a GED or Home School certificate. Preference will be given to students who seek to enter the Christian Ministry, and/or who have exhibited a strong interest in Community Service and Humanitarian Service.

  • Average Award: $2,500
  • Award Type: Single Year. Previous recipients are encouraged to re-apply in consecutive years.
Volunteerism & Philanthropy Education - Higher Education Vocational & Trade Education +1 more

Sonoco Scholarship

Central Carolina Community Foundation
Private
United States
Unspecified amount

About

Central Carolina Community Foundation is a nonprofit organization that helps generous people give back to the Midlands of South Carolina in ways that matter. Since 1984, we’ve been a trusted partner, helping individuals, families, and businesses make smart, meaningful contributions that support local nonprofits, scholarships, and community projects.

Sonoco Scholarship ($2,500)

This renewable scholarship is for dependents of qualified Sonoco employees of U.S. domestic facilities. 

Education - Higher Education Vocational & Trade Education Education - High School +1 more

Joseph S. Onisko, Jr. Environmental Sciences Scholarship

Community Foundation of the Lowcountry
Private
United States
Unspecified amount
The Joseph S. Onisko, Jr. Environmental Sciences Scholarship, established in 2020 by the Community Foundation of the Lowcountry, supports high school seniors from southern Beaufort County pursuing a degree in Environmental Sciences. This scholarship honors Joseph S. Onisko, Jr. and aims to assist students with outstanding achievements, a minimum GPA of 3.2, and a focus on marine sciences. The foundation has invested over $125 million to enhance the Lowcountry community.
Education - Higher Education Environmental Education Marine Biology +1 more

JUSFC Institutional Grant

Japan-United States Friendship Commission
Federal Government
Japan, United States
Unspecified amount
The Japan-U.S. Friendship Commission (JUSFC) is a federal agency established in 1975 to enhance U.S.-Japan relations through educational and cultural exchanges. JUSFC supports various initiatives in arts, education, and global challenges, focusing on fostering partnerships between U.S. and Japanese organizations. The Commission aims to facilitate dynamic people-to-people exchanges, ensuring a robust understanding between the nations and promoting collaborative projects that enrich both societies.
Asian / Pacific Island Culture & Heritage Cross-Cultural Understanding & Exchanges Public Policy +1 more

Summit Credit Union Grant

Summit Credit Union
Private
United States
US $500 - US $1,000
The Summit Credit Union Grant emphasizes charitable giving through partnerships that support equity, financial wellbeing, and women's empowerment. Committed to reducing inequities, the credit union seeks nonprofit organizations that align with these pillars to foster community growth. Eligibility criteria include being a 501(c)(3) nonprofit serving specific areas and submitting an online application. However, funding is not available for individuals, religious or political organizations, or any entities that discriminate based on various identities.
Women & Girl Services Financial Literacy Civic Leadership Development +1 more

Kelsey Nicole Cooper Scholarship Fund

Community Foundation Serving Western Virginia
Private
United States
Approximately US $1,000
The Kelsey Nicole Cooper Scholarship Fund, administered by the Community Foundation Serving Western Virginia, offers scholarships to deserving students from the Martinsville Henry County community, emphasizing volunteerism. Eligible applicants must be graduating seniors or graduates from local high schools, enrolled or planning to enroll in accredited colleges, and maintain a minimum GPA of 2.5. Preference is given to those attending Virginia Tech or involved in the CHILL youth task force. For more information, contact the Foundation.
Education - Higher Education Vocational & Trade Education Academic Scholarship Programs +1 more

Ross Scholarship Fund

The Foundation for Enhancing Communities
Private
United States
US $2,000 - US $16,000
The Ross Scholarship Fund provides financial support to graduating high school seniors from Franklin County who plan to pursue higher education. Applicants must demonstrate academic achievement (minimum GPA of 2.5) and financial need. The scholarship renews for up to four years, contingent upon maintaining eligibility requirements. Extra consideration is given to students from the Chambersburg Area School District, ensuring that deserving local students receive the support they need to succeed in their higher education endeavors.
Education - Higher Education Academic Scholarship Programs Vocational & Trade Education +1 more

Kansas City Pride Community Alliance Scholarship Fund

Greater Kansas City Community Foundation
Private
United States
US $1,000

The Greater Kansas City Community Foundation is one of the most well-respected, knowledgeable leaders on charitable giving in the nation. We make giving convenient and efficient for donors through donor-advised funds and other types of charitable giving accounts that maximize and organize giving.

Our Mission

The Community Foundation’s mission is to improve the quality of life in Greater Kansas City by increasing charitable giving, educating and connecting donors to community needs they care about, and leading on critical community issues.

Kansas City Pride Community Alliance Scholarship Fund

The KCPCA Scholarship provides needed financial assistance to support LGBTQ+ students who are resident of Jackson, Clay, Platte or Buchannan counties in Missouri and Johnson, Wyandotte or Douglas counties in Kansas of all background and educational interests. We prioritize LGBTA+ students who need it most and who have some or all of the following experiences:

  • People of color, Black, Indigenous
  • Trans, Non-binary, Gender Expansive, Two spirit people
  • People with disabilities – including people living with chronic illnesses, HIV, neurodivergence, mental health challenges
  • People who have or are experiencing housing instability
  • People living in rural areas
  • People who have financial need without access to financial support
  • People who have experienced family rejection.

Award

  • $1,000
Education - Higher Education LGBTQIA+ Services Indigenous Services +1 more

Eugene "Babe" Fabrizi Fund to Educate Music Students

Pittsburgh Foundation
Private
United States
Up to US $3,000

The Pittsburgh Foundation

Established in 1945, The Pittsburgh Foundation is one of the nation’s oldest community foundations and as of 2022 is the 18th largest of more than 750 similar foundations across the United States.

As a community foundation, its resources comprise endowment funds established by individuals, businesses and organizations with a passion for charitable giving and fulfilling the Foundation’s mission of improving quality of life for all in the region. The Foundation currently manages about 2,500 individual donor funds and, together with its supporting organizations and its affiliate, The Community Foundation of Westmoreland County, has assets of $1.386 billion (2022). Grantmaking benefits a broad spectrum of basic needs and development opportunities within Pittsburgh and beyond.

Scholarships

The Pittsburgh Foundation and The Community Foundation of Westmoreland County provide scholarship opportunities for local students to pursue their educational goals. Scholarships are available for graduating high school seniors, undergraduates, graduate, medical and professional school students who are attending community colleges, four-year universities and career/technical schools.

Eugene "Babe" Fabrizi Fund to Educate Music Students

The Eugene “Babe” Fabrizi Fund to Educate Music Students of The Pittsburgh Foundation was created to support young or adult musicians.

Award Type: Single Year. Previous recipients are encouraged to re-apply in consecutive years.

Education - Higher Education Music Theater

Atz, Julia L. Scholarship Fund

Noble County Community Foundation
Private
United States
US $2,500
The Julia L. Atz Scholarship Fund, established by the Noble County Community Foundation, offers $2,500 to college seniors or post-graduate students pursuing careers in classical music performance or conducting. Applicants must maintain a GPA of 3.00 or above and may reapply for funding in subsequent years. Preference is given to Indiana residents, reflecting the Foundation's commitment to supporting local talent and enhancing the cultural landscape of the community.
Classical Music Academic Scholarship Programs

Rainin Visionary Scientist Award

Kenneth Rainin Foundation
Private
United States
Up to US $300,000

Rainin Visionary Scientist Award 

The Kenneth Rainin Foundation believes that early support for innovative ideas can lead to improvements in preventing, predicting, diagnosing and treating Inflammatory Bowel Disease (IBD). Our Health grantmaking enables researchers worldwide to test ideas, gather and share data, and collaborate to advance the understanding of IBD.

The Rainin Visionary Scientist Award will provide grants of $300,000 each over two years to support three outstanding postdoctoral investigators whose work has the potential to advance the understanding of IBD and related biological systems. This award is designed to help postdocs based in the US who are actively preparing to transition to an independent faculty position develop innovative research programs and strengthen their trajectory toward independent scientific careers. By supporting promising scientists early in their careers, the Foundation seeks to accelerate discoveries that may ultimately improve the lives of people living with Crohn’s disease and ulcerative colitis.

Competitive proposals will demonstrate:

  • A novel or creative scientific approach
  • Strong potential to advance understanding of IBD biology or treatment
  • Clear intellectual leadership from the applicant
  • Feasible research aims that can be accomplished within two years
  • A strong mentorship environment that supports career development

The Foundation particularly values projects that introduce new ideas, technologies or conceptual approaches to the study of IBD and relevant scientific disciplines.

Funds may be used for postdoctoral salary support, supplies, other direct research expenses necessary to complete the proposed work and travel to relevant scientific meetings. Awardees are expected to attend the Rainin Foundation Innovations Symposium during the award period. Economy/coach air travel costs for this meeting in San Francisco should be included in the budget.

The award provides $300,000 over two years. The grant period is October 1, 2026-September 30, 2028.

Genetics & Genomics Immune System Diseases Microbiomes

Dorothy B. & Charles E. Thomas Scholarship

Grand Rapids Community Foundation
Private
United States
US $2,000 - US $5,000

Grand Rapids Community Foundation

Connecting people, passion and resources

The Community Foundation is a nonprofit organization that connects people, passion and resources. With our partners, the Community Foundation uses the tools of philanthropy to find solutions to pressing issues. We provide grants to support the work of nonprofits, scholarships to local students and other forms of support to communities working to eliminate barriers to opportunity, prosperity and belonging.

Our Mission is to build and manage our community’s permanent endowment and lead the community to strengthen the lives of its people.

We envision a magnetic and interconnected West Michigan community.

Integrity, Excellence, Inclusion, Sustainability and Bold Aspirations

Give and Receive Openly, Build Trust with Each Other, Create Brave and Safe Space, Embrace Vulnerability, Accountability

Our North Star

For West Michigan to grow and prosper, we must make sure that everyone can apply their talents and creativity to fuel our future. It is only by connecting across perspectives and overcoming inequities that we can build and sustain an inclusive economy and thriving community.

Opportunities for students

Apply for scholarships to support your ambitions

Each year Grand Rapids Community Foundation supports hundreds of students on their college or career training journeys. We are excited to remove barriers to academic success so that students like you can pursue what you're passionate about.

Scholarship Fund Details

Support for West Michigan Students

Attending college or trade school increases opportunity and opens doors to careers. Donor partners who establish a scholarship fund give students a boost on their path to higher education. Students who complete the general scholarship application are considered for these scholarships.

Open to students who are residents of Kent County. Preference to Challenge Scholar students through 2032.

Education - Higher Education College Success / Persistence Educational Access & Equity

The Ryan Legacy Scholarship

Community Foundation of Carroll County
Private
United States
Unspecified amount

The Community Foundation of Carroll County supports nearly 70 academic, sports, special circumstances, and 4-H scholarships. Search scholarships by name, or sort by application type.

The Ryan Legacy Scholarship

Melanie Ryan was an incredible mother, wife, friend, and nurse for almost 30 years. Her kindness, generosity, and compassion will be remembered forever by those who had the honor to know and love her. She passed away from Metastatic Triple Negative Breast Cancer in June of 2024. Her husband Tom was the love of her life and also and incredibly kind and caring husband, father, manager and friend. He passed away from Hodgkins Lymphoma in November of 2022. This scholarship remembers this beautiful couple by assisting graduating high school seniors and current college students in pursuing a college degree. Preference will be given to student athletes in memory of Tom’s love of sports and students pursuing a healthcare related degree in memory of Melanie’s incredible nursing skills and heart.

Education - Higher Education Nursing Sports & Athletics +1 more

Jacques Parker and Marie Deguard Scholarship

The Berkshire Taconic Community Foundation
Private
United States
Unspecified amount
The Jacques Parker and Marie Deguard Scholarship, offered by the Berkshire Taconic Community Foundation, supports high school seniors in the region pursuing higher education in visual arts or architecture. Scholarships are renewable for up to five years, covering costs for college, apprenticeships, or specialized courses. This initiative aims to promote economic mobility and provide opportunities for creativity, ensuring a lasting impact on students' lives in Berkshire, Columbia, northeast Dutchess, and northwest Litchfield counties.
Architecture Education - Higher Education Career / College Preparation

Large Grants for Nonprofit Organizations in District of Columbia Highlights

Looking for large grants for nonprofit organizations in District of Columbia?


Read more about each grant below or start your 14-day free trial to see all large grants for nonprofit organizations in District of Columbia recommended for your specific programs.

Last updated: October 5, 2026. Next update: November 1, 2026.

Grant Insights : Large Grants for Nonprofit Organizations in District of Columbia

Grant Availability

How common are grants in this category?

Common — grants in this category appear regularly across funding sources.

300+ Large Grants for Nonprofit Organizations in District of Columbia grants for nonprofits in the United States, from private foundations to corporations seeking to fund grants for nonprofits.

100+ Large Grants for Nonprofit Organizations in District of Columbia over $25K in average grant size

100+ Large Grants for Nonprofit Organizations in District of Columbia over $50K in average grant size

55 Large Grants for Nonprofit Organizations in District of Columbia supporting general operating expenses

200+ Large Grants for Nonprofit Organizations in District of Columbia supporting programs / projects

600+ Grants on Instrumentl focused on Food Access & Hunger

3,000+ Grants on Instrumentl focused on Education

Grant Deadline Distribution

Over the past year, when are grant deadlines typically due for Large grants for Nonprofit Organizations in District of Columbia?

Most grants are due in the first quarter.

Q1
28.0%
Q2
25.0%
Q3
25.7%
Q4
21.3%

Typical Funding Amounts

What's the typical grant amount funded for Large Grants for Nonprofit Organizations in District of Columbia?

Grants are most commonly $50,000.

$250 $250 Min.
$50,000 $50 K Median
$326,838 $326.8 K Average
$19,910,496 $19.9 M Max.

Average Grant Size

What's the typical amount funded for District of Columbia?

Grants are most commonly $191,869.

$191,869

Total Number of Grants

What's the total number of grants in Large Grants for Nonprofit Organizations in District of Columbia year over year?

In 2024, funders in District of Columbia awarded a total of 71,691 grants.

2022 71,046

2023 67,427

2024 71,691

Top Grant Focus Areas

Among all the Large Grants for Nonprofit Organizations in District of Columbia given out in District of Columbia, the most popular focus areas that receive funding are Education, Human Services, and Community Improvement & Capacity Building.

1. Education

2. Human Services

3. Community Improvement & Capacity Building

Funding Over Time

How is funding for Large Grants for Nonprofit Organizations in District of Columbia changing over time?

Funding has increased by 27.77%.

2022 $11,110,524,503

2023 $10,735,067,064
-3.38%

2024 $13,715,894,150
27.77%

District of Columbia Counties That Receive the Most Funding

How does grant funding vary by county?

District Of Columbia receive the most funding.

County Total Grant Funding in 2024
District Of Columbia $12,786,708,728