Best Large Grants for Nonprofit Organizations in District of Columbia

The African-American Community Foundation - Yokley-Gamblin Family Scholarship, established in 2019, aims to support underrepresented ethnic minority students from Montgomery County in their educational journeys. This scholarship is awarded to students who demonstrate financial need, excel in community involvement, and maintain a GPA of 3.0 or below. Recipients can use the funds for tuition at accredited institutions, including technical schools and colleges, fostering educational opportunities for deserving candidates.

The We Raise Foundation's Emerging Leader Grant supports individuals aged 20-35 at Christian organizations developing innovative programs addressing poverty, violence, and inequality. With a total of $15,000 over two years, the grant allocates $10,000 for program support and $5,000 for leadership development, including coaching and conferences. This initiative aims to foster impactful leaders who inspire, communicate effectively, and engage deeply with their communities, ultimately creating lasting change.

About

Central Carolina Community Foundation is a nonprofit organization that helps generous people give back to the Midlands of South Carolina in ways that matter. Since 1984, we’ve been a trusted partner, helping individuals, families, and businesses make smart, meaningful contributions that support local nonprofits, scholarships, and community projects.

Katherine K. Greiner Scholarship ($3,000) 

This renewable scholarship was established to support students who plan to become elementary, middle or high school teachers. 

Who We Are

The GHACF is a team of dedicated individuals passionate about improving the lives of everyone in our community – connecting people, resources and solutions that create a lasting impact.

The GHACF is your partner. We can’t succeed alone – our work is possible only through the combined efforts of our nonprofit partners, community members, and passionate individuals. We are a bridge to help you make things happen and impact our community, together. We will walk alongside you to support and assist you in your philanthropic goals, now and forever.

Floto-Peel Family Fund

Medicine.

Checks are made payable to and mailed directly to the college after you have returned the required scholarship acceptance paperwork, thank you note, and photo. This is usually by early August.

The CDC is providing supplemental funding to 34 American Indian and Alaska Native Tribes and organizations through the Strengthening Public Health Systems and Services initiative. Eligible recipients can apply for new project plans for FY 2027. This funding aims to align measurable outcomes with the Healthy People 2030 goals, enhancing public health services and systems in Indian Country.

The Amber Huber Memorial Scholarship honors a dedicated athlete from Byron High School, supporting students who embody hard work and competitive spirit. This scholarship is available to students striving to achieve their athletic goals, reflecting Amber's legacy. It is renewable for four years, ensuring continued support for those who meet the criteria. Academic performance will be moderately considered in the selection process, fostering the development of future leaders in athletics.

Columbus Matrix Foundation Scholarship

Since the early days of print journalism, The Association for Women in Communications has evolved to become the overarching professional organization to unite communicators across a vast spectrum of disciplines-from print and broadcast journalism, to graphic design, photography, public relations, advertising, marketing, new media, and much more.

Award Amount:

• Up to four scholarships of $10,000 payable over four years at $2,500 per academic year.

The Helen T. Bianca Nursing Scholarship, offered by the Community Foundation of Greater New Britain, supports high school seniors from New Britain and Berlin who are pursuing nursing degrees at accredited institutions. Applicants must show financial need and commitment to community service through volunteer work. A personal essay detailing their dedication to nursing and community impact is required. This scholarship aims to foster future nurses dedicated to improving healthcare in their communities.

The Founders Project Fulfillment Grant, offered by the Children's Theatre Foundation of America (CTFA), is dedicated to supporting 501(c)(3) IRS-certified theatres with a strong commitment to artistic excellence for young audiences. Eligible organizations must have a minimum operating budget of $1,000,000 and a proven track record of diversity in leadership, making this grant a vital resource for fostering inclusive theatre experiences for children and families.

Jean Griswold Foundation 

The Jean Griswold Foundation (JGF) is a non-profit organization dedicated to supporting Caregivers through educational opportunities and scholarships. 

Mission

The mission of the Jean Griswold Foundation is to support Caregivers by providing educational scholarships* to enable them to further their training, enhance their careers, and better assist the clients they serve.

By offering educational scholarships, our Foundation will not only make a positive impact on the Caregivers themselves, but also the clients they assist and the home healthcare agencies where they are employed, as well as help advance the overarching home-care industry.

The Jean Griswold Foundation is proud to continue the service created by Dr. Jean Griswold, through spearheading this strategic journey of growth and professional development.

Scholarships

The Jean Griswold Foundation Scholarship Program awards scholarships to deserving Caregivers who wish to further their education in a care-related field. Applicants do not have to be associated with Griswold in any way, and the funds will be paid directly to the institution where the caregiver will be receiving education.  

Summer Scholarship Program

The Jean Griswold Foundation has awarded over $150,000 in scholarships to exceptional Caregivers nationwide since 2022. 

The Louis J. (Mattioli) Matt Music Scholarship, offered by the Community Foundation of Greater New Britain, supports graduating seniors from public high schools in New Britain, Newington, or Plainville. Eligible students must pursue a bachelor's degree in music education or performance, demonstrate outstanding musical talent, and rank in the top 25% of their class. Financial need is also a key consideration, encouraging talented young musicians to further their education and hone their skills.

Marion Community FoundationMarion Community Foundation is the area’s leading philanthropic organization, providing charitable donors the opportunity to easily create endowment funds to benefit and support our community through grants and scholarships. We serve communities throughout Marion County through philanthropy, leadership, and civic engagement.Mission: To continually improve the Marion Area community through philanthropy, leadership and civic engagement. Dr. Kathy Dixon Memorial ScholarshipThe Dixon Scholarship supports the educational careers of area students wishing to attend Marion Technical College and The Ohio State University at Marion. Applicants can be from any high school in Marion and its six contiguous counties. Special consideration is given to college upperclassmen who are majoring in the fields of science or health care.

The Abbvie Parkinson’s Disease Grant aims to enhance the understanding and management of subcutaneous infusion therapies for advanced Parkinson’s disease. As these therapies become more prevalent, it is crucial for Movement Disorder Specialists and General Neurologists to develop confidence in identifying, mitigating, and managing infusion site events. This grant seeks to provide essential education and resources to support safe and effective treatment options for patients experiencing motor fluctuations.

The Next Generation Graduate Scholarship, established by the Architects Foundation, supports aspiring architects from diverse backgrounds. With an award of up to $20,000 over five years, it aims to enhance education accessibility in architecture. This initiative honors Whitney Young Jr.'s call for a more responsible profession, inviting students from technical schools, community colleges, and non-NAAB programs to apply. The scholarship not only aids in educational pursuits but also fosters a network of future leaders in architecture.

The Calendar Year 2022 Disaster Water Grants program, administered by the USDA's Rural Utilities Service, aims to provide funding for water infrastructure repairs in areas affected by federally declared disasters during 2022. Eligible applicants include public bodies, non-profit organizations, and tribes, all required to demonstrate capacity and legal authority. The grants support not only repairs but also the enhancement of system resilience to mitigate future risks.

The NEI Institutional Mentored Physician Scientist Award (K12 Clinical Trial Optional) aims to foster innovative research career development for clinically trained vision scientists. This funding opportunity encourages institutions to develop programs that prepare scholars for independent research careers, particularly in minimal risk clinical trials. Emphasis is placed on recruiting underrepresented groups in research, ensuring a diverse pool of clinician investigators engaged in vision research.

The J.M.K. Innovation Prize, awarded by The J.M. Kaplan Fund, supports early-stage social innovators tackling critical issues in environment, heritage conservation, and social justice. With up to $175,000 in funding and tailored support over three years, it empowers organizations to pilot transformative solutions. The Prize fosters collaboration among awardees, providing resources and mentorship to enhance their impact. Open to both non-profit and mission-driven for-profit entities, it addresses the funding gap for innovative, high-potential projects.

The U.S. Department of Justice is inviting applications for the FY26 Coordinated Tribal Assistance Solicitation (CTAS) to streamline the grant process for federally recognized tribes. This initiative combines various competitive funding opportunities into a single application, allowing tribes to address public safety and victimization comprehensively. Eligible areas include criminal justice, substance use, and support for victims of domestic violence. The deadline for applications is October 22, 2026.

The Vadon Foundation Grant supports innovative, community-based initiatives aimed at sustaining healthy indigenous nations. By empowering visionary changemakers, the foundation addresses multi-generational challenges through focused programming in areas like language revitalization, community leadership, and addressing crises such as food insecurity. The foundation seeks to foster self-determination and sustainability within native communities, ensuring that future generations can thrive culturally and socially.

Margot Eiseman Scholarship Fund

Established to carry on Margot Eiseman's legacy as an artist and educator by helping young artists pursue their dreams of an education and career in art.

Amount: Varies

• $1,000-$3,000

Number of awards:

• Varies

Renewal:

• Must reapply annually by submission of a new application.

The Indian Highway Safety Traffic Records Forum Grant is exclusively available for federally recognized tribes without an existing grant for FY 2027. This program, managed by the Bureau of Indian Affairs, supports initiatives aimed at enhancing traffic safety through data collection and analysis. Eligible tribal employees can apply for funding to cover registration and travel expenses for attending the Traffic Records Forum from August 3-5, 2027, promoting improved traffic records and safety measures.

The Ed Hiestand Memorial Veterinary Student Scholarship, awarded by the National Wildlife Rehabilitators Association, invites current veterinary students to submit papers on wildlife rehabilitation topics. The scholarship includes a $1000 award, symposium registration, and a banquet ticket. Winners will present their findings at the NWRA Symposium, with eligibility requiring original, unpublished manuscripts. This initiative supports veterinary education and promotes wildlife conservation efforts.

Multiple Sclerosis Foundation

The Multiple Sclerosis Foundation, known in the MS community as MS Focus, is a nonprofit organization focused on providing free services that address the critical needs of people with MS and their families, helping them maintain the best quality of life. 

The symptoms of MS are unpredictable and may increase in severity over time. This presents physical, emotional, and financial challenges families must face. MS Focus is here to provide the support, education, and assistance needed to adapt to these challenging circumstances. Our primary focus is on providing individuals with MS the help they need to maintain their health and well-being, to continue to be productive and independent, and to keep a roof over their heads and a safe environment in their home. We do so with empathy, resourcefulness, and conscientious care.

Whom does MS Focus serve?

Our resources assist people who have MS, their families and caregivers, regional support groups, and healthcare professionals. Our programs and grants are available in the 50 U.S. states and Puerto Rico. Online resources, such as our educational materials or audio programs, are available throughout the world.

Assistive Technology Program

The Assistive Technology (AT) Program may help locate, partially fund, or provide full funding for one of a wide range of devices. These allow those with MS to function more independently in their daily lives, as well as more easily participate in recreational, educational, and vocational activities. These include:

• Aids for daily living
• Communication devices
• Computer aids
• Environmental control systems
• Home and vehicle modifications
• Orthotics
• Seating, positioning, and mobility devices
• Aids for vision and hearing
• Cooling aids

About

Central Carolina Community Foundation is a nonprofit organization that helps generous people give back to the Midlands of South Carolina in ways that matter. Since 1984, we’ve been a trusted partner, helping individuals, families, and businesses make smart, meaningful contributions that support local nonprofits, scholarships, and community projects.

Bertha and Addison Bostain, Sr. Scholarship ($2,300)

This renewable scholarship is available to students who will or have graduate from a high school located in Chapin, South Carolina. 

The Yass Prize & STOP Awards Initiative aims to revolutionize education by recognizing and supporting exceptional education providers focused on Sustainable, Transformational, Outstanding, and Permissionless (STOP) education. Established in 2021, the initiative awards funds to organizations serving Pre-K to 12th grade students across the United States, fostering impactful partnerships and innovative practices. With a commitment to transforming educational experiences, the initiative celebrates the vital work of educators in response to contemporary challenges.

The RFA-FD-23-001 funding opportunity aims to support clinical trials for orphan products targeting rare diseases. It focuses on evaluating the efficacy and safety of treatments to address unmet medical needs. By promoting innovative and collaborative trial designs, the FDA seeks to enhance the approval rates of effective therapies for rare conditions, ultimately benefiting patients and advancing drug development in this critical area.

About Us

We enable donors and nonprofit partners to tackle the most critical needs facing San Diegans.

Mission & Values

Our vision is for just, equitable and resilient communities.

Our mission is to inspire enduring philanthropy and enable community solutions to improve the quality of life in our region.

We value all people, all partners and our region.

Common Scholarship Application

Achieve your Higher Education Dreams

In just one application, our Common Scholarship Application provides students access to more than 150 scholarship opportunities with awards ranging from $1,000 to more than $5,000.

In 2025, San Diego Foundation awarded a record-breaking $5.5 million in scholarships to nearly 1,400 students.