Best Addiction and Substance Abuse Grants in Arizona

With a mission to prevent substance use, Arizona Governor's Office of Youth, Faith and Family provides Arizona addiction and substance use organizations with up to US $200,000 to implement trauma-informed primary prevention programs. Community partners in high-need areas can strengthen protective factors and reduce long-term risks of drug and alcohol misuse.

Arizona schools, districts, tribes, and community-based organizations can seek funding to create or expand community learning centers offering academic enrichment and diverse youth programs outside school hours in Arizona. Focused on after-school and summer learning, the Arizona Department of Education invites applicants serving Title I-eligible sites to include activities like drug and violence prevention, counseling, and health education that support students’ overall success.

Arizona nonprofit organizations and academic institutions hosting charitable events can apply for the AZ Blue Foundation’s sponsorships, with awards up to US $25,000 for events advancing health. Funding supports work in chronic conditions, health equity, mental health, and substance use disorders, which may benefit addiction and substance abuse programs in Arizona.

About CommonSpirit

A calling that defines and unites

At CommonSpirit Health, we passionately care for the most vulnerable, relentlessly innovate how and where healing can happen and believe in uniting to benefit the common good. Our expansive network spans diverse communities, uniquely positioning us to meet their changing needs, improve population health and help chart the path to health equity.

Our mission, vision and values inform every aspect of our work each day and remind us that we serve our patients, their families, our communities – and each other. Our community health, research and home health programs help us address the primary barriers to healthier communities.

Sponsorship requests

We’re proud to support nonprofits that expand access to care, advance health equity and healthier communities. Learn more about our priorities.

Supporting our communities

CommonSpirit Health and our local facilities support nonprofit organizations that share our mission, vision and values. We give priority to programs that improve access to care and promote health equity and healthier communities.

CommonSpirit is proud to support nonprofit organizations that help improve the health and well-being of our communities. Guided by our mission, vision and values, we prioritize projects that focus on advancing health equity, improving access to care and improving community wellness.

Arizona-based nonprofit organizations and academic institutions working on addiction, substance use disorder, or related mental health programs can apply for the Foundation for Community and Health Advancement’s Mental Health Matters Grant, with awards up to US $125,000 for direct project expenses. Funding supports programmatic impact and applied research that expand scalable, measurable community resources.

Nonprofit organizations and academic institutions hosting Arizona charitable events tied to addiction and substance use disorder work can seek sponsorship to support their efforts. Grants from Foundation for Community and Health Advancement help Arizona groups fund events aligned with chronic conditions, mental health, health equity, and substance use disorder priorities, with awards up to US $25,000.

Arizona addiction and substance use research organizations can access funding through the National Institutes of Health to test SBIRT/P approaches for alcohol, tobacco, and other drug use in adults facing health disparities. Projects must prospectively evaluate screening, brief intervention, and referral to treatment or prevention in collaboration with healthcare and community partners across eligible U.S. jurisdictions.

Nonprofit and local government organizations working on addiction, substance use, and related health or safety programs in Arizona may be eligible if they serve Native American communities. Focused on education, health, addiction treatment, housing, and cultural or environmental initiatives, the Confederated Tribes of Siletz Indians invites applications from Native American organizations across the U.S.

Grants from the National Institutes of Health help Arizona and other U.S. researchers test SBIRT/P approaches for alcohol, tobacco, and other drug use in adults experiencing health disparities. Eligible institutions can propose prospective clinical trials that implement screening, brief intervention, and referral to treatment or prevention in collaboration with healthcare and community partners.

Arizona organizations providing addiction and substance use prevention services can apply for the Substance Use Block Grant to support evidence-based programs, screenings, and behavioral health and substance abuse assessments. Administered through the Arizona Health Care Cost Containment System and SAMHSA, this funding also supports trauma-informed prevention efforts addressing vaping, alcohol, marijuana, polysubstance, and emerging drug trends.

Arizona 501(c)(3) nonprofits providing substance abuse treatment, recovery support, or related services can apply for US $5,000 - US $50,000 from the Slave 2 Nothing Foundation. Focused on addiction recovery and anti-human trafficking, the funder invites organizations in states with In-N-Out Burger locations, including Arizona, that help individuals and families gain freedom and healing.

Public and private organizations in Arizona working on substance use prevention and youth mental well-being can join this five-year collaborative, which funds trauma-informed, culturally competent programming for foster youth and caregivers. With a mission to strengthen prevention statewide, Arizona Governor's Office of Youth, Faith and Family provides training, technical assistance, and peer-led support to implement evidence-based programs.

This funding opportunity invites Small Business Technology Transfer (STTR) grant applications aimed at developing FDA-regulated medical products for patients with opioid and stimulant use disorders. Projects may focus on pharmacotherapeutics or diagnostic devices, including software. The initiative seeks to address the ongoing opioid crisis by supporting innovations that enhance treatment options for individuals and communities affected by these disorders.

The Drug-Free Communities (DFC) Support Program aims to foster collaboration among community coalitions to combat youth substance use. Established by the Drug-Free Communities Act of 1997, it encourages partnerships among various stakeholders, including governmental and non-profit agencies. The program focuses on reducing substance use among youth and promoting protective factors within communities. This funding opportunity is available for those who have completed the initial funding cycle or experienced funding interruptions, supporting their ongoing efforts to create a healthier environment for youth.

The Drug-Free Communities (DFC) Support Program, initiated by the Drug-Free Communities Act of 1997, aims to bolster community coalitions dedicated to preventing youth substance use. Funded by the US HHS's Substance Abuse and Mental Health Services Administration (SAMHSA), this program focuses on collaboration among various stakeholders, including government and non-profit entities, to effectively reduce substance abuse among youth and promote protective factors within communities.

The Strengthening Services to Prevent the Infectious Disease Consequences of Drug Use initiative aims to enhance prevention services for infectious diseases among people who use drugs (PWUD). It encompasses two components: a biennial survey to assess service gaps and capacity, and increased support for testing and treatment services. The initiative seeks to improve data utilization in service provision, ultimately increasing testing for HBV, HCV, and HIV, and ensuring more PWUD engage in treatment and care.

Organizations providing research education experiences in substance use and addiction can apply for NIH funding of up to US $1,250,000. Focused on skills-development courses and hands-on research experiences, this program supports diverse trainees in biomedical and behavioral sciences, and Arizona programs working on addiction and substance use disorders may be eligible.

Clinician-scientist training programs focused on addiction and substance use disorders in Arizona and other eligible U.S. locations can apply for institutional career development support, with awards up to US $750,000. Grants from the National Institutes of Health help institutions provide intensive, supervised research training that leads Scholars toward independent substance use and substance use disorder research careers.

Research institutions and teams conducting HIV and substance use studies can apply for up to US $1,500,000 in funding, including work connected to Arizona. Focused on advancing prevention, treatment, and cure research among people who use drugs, the National Institutes of Health supports projects from basic science through clinical and implementation research.

The Chemical Countermeasures Research Program (CCRP) Initiative aims to support vital research on the harmful effects of acute exposure to Ultra-Potent Synthetic (UPS) opioids, including fentanyl and its combinations. This funding opportunity encourages studies that enhance understanding and mitigation strategies for these substances, focusing on both immediate and long-term health impacts. Applications are due by 5:00 PM local time, with optional Letters of Intent accepted 30 days prior to the proposal deadline.

The HEAL Initiative aims to combat the opioid crisis through action-oriented research that enhances the translation of addiction epidemiology, prevention, treatment, and recovery services into practice. It prioritizes scalable, evidence-based approaches targeting various levels, including individual and community. The initiative supports a range of methods for research deployment, emphasizing collaboration between researchers and decision-makers to improve outcomes for those affected by addiction and related chronic pain.

Arizona research institutions and clinical trial teams studying anesthesia, addiction medicine, and pain medicine can access funding through the US Department of Health & Human Services: Food and Drug Administration for evidence-based projects. Awards of US $2,000,000 support clinical trials and related research on analgesics, anesthetics, substance use disorders, and opioid safety, including pediatric outcomes.

The NIDA Research Education Program (R25) aims to enhance the training of a workforce skilled in biomedical, behavioral, and clinical research, particularly regarding substance use disorders. This program supports educational activities that prepare clinicians and clinical researchers. Applications are due by 5:00 PM local time, with optional Letters of Intent encouraged 30 days prior to the full proposal deadline. This initiative does not fund non-research-related clinical training.

The Tobacco, Alcohol, and Cannabis Policy Research for Health Equity grant aims to support research on policies affecting tobacco, alcohol, and cannabis use in the U.S. This initiative focuses on how these policies impact populations facing health disparities. Key components include engaging community organizations to advance equity in cancer prevention. Important deadlines for applications range from February 2025 to October 2027, providing opportunities for both standard and renewal submissions.

The Tobacco, Alcohol, and Cannabis Policy Research for Health Equity (R21 Clinical Trial Optional) aims to fund projects that explore policies related to tobacco, alcohol, and cannabis in the U.S. The focus is on understanding how these policies affect usage and exposure among disadvantaged populations. Engaging community organizations is essential for promoting equity in cancer prevention. This initiative is crucial for advancing health equity and reducing disparities in substance use.

The Mechanism for Time-Sensitive Substance Use Research (R21 Clinical Trial Optional) invites applications that address urgent research needs in substance use epidemiology and health services. This funding opportunity encourages pilot studies focusing on emerging drug issues, unexpected prescription drug abuse trends, and timely medical system challenges. Letters of Intent are recommended 30 days before the proposal deadline, emphasizing the necessity for rapid review and funding to address pressing scientific questions.

Organizations providing training and technical assistance on opioid and stimulant misuse in rural communities, including Arizona, can apply for funding to support prevention, treatment, and recovery support services. Substance Abuse and Mental Health Services Adminis offers up to US $650,000 for ten regional centers and one national coordinating office focused on substance use disorders, including polysubstance use.