Best Foundation Grants for Nonprofits in Illinois

The NIDDK Multi-Purpose Resource-Related Research Centers Cooperative Agreement (U2C) invites applications to enhance research capabilities in areas such as obesity and diabetes. These centers provide specialized services, including technical support and data coordination, primarily to clients at other institutions lacking necessary expertise. This initiative aims to bolster high-impact research through collaboration and experiential training, addressing critical health challenges aligned with NIDDK's mission.

About

Community Foundation of Greenville bridges philanthropy and purpose in Greenville County, helping people make their charitable giving simpler and more powerful for 70 years. We strategically match diverse needs and opportunities in Greenville County with philanthropic resources.

Vision:

Community Foundation of Greenville will be the leading catalyst for developing assets and unlocking potential to meet the needs of an inclusive and equitable community.

Mission:

Community Foundation of Greenville improves the lives of Greenville County residents through strategic philanthropy, community investment, and collaborative leadership.

Obermier Scholarship Fund in Memory of John N. Obermier, Edith M. Obermier and Mary Belle Obermier

Purpose

Mary Belle Obermier established this scholarship with a gift from her estate in 2012. Her intent was to help academically deserving students who need financial assistance to be able to attend college and to give preference to qualified students who are committed to a career in the United States Navy. The preference for naval students is in recognition of the US Navy careers of her deceased husband, John, and his deceased first wife, Edith, who were both veterans of World War II.

Criteria:

• Applicants must demonstrate financial need (economically disadvantaged).
• Applicants must have a current academic GPA of 3.0 or higher.
• Applicants must be enrolled/accepted to an institution of higher learning prior to applying.
• Applicants must submit one letter of recommendation from a teacher, employer, or clergy.

Preference in the selection process will be given in the following order to qualified students who are:

students who are committed to a career in the United States Navy

residents of Greer, SC

residents of South Carolina and

residents of all other states

Pfizer’s Core Values of Social Responsibility and Philanthropy

About

We’re in relentless pursuit of breakthroughs that change patients’ lives. We innovate every day to make the world a healthier place. It was Charles Pfizer’s vision at the beginning and it holds true today.

Improving Health Outcomes in Patients with ATTR-CM Through the Development of a Shared Decision-Making Tool (Decision Aid)

Overview

Transthyretin Amyloid Cardiomyopathy (ATTR-CM) is a progressive, lifethreatening condition associated with significant morbidity, mortality, and burden on patients, caregivers, and healthcare systems. The multisystemic disease course is often characterized by diagnostic delays, complex treatment pathways, and evolving therapeutic options, which can create uncertainty and decisional conflict for patients and clinicians alike. Shared decision-making (SDM) has emerged as a critical component of patientcentered care1, particularly in complex and preference-sensitive conditions such as ATTR-CM. Well-designed decision aids can support meaningful dialogue between patients and healthcare professionals by improving understanding of disease trajectory, treatment options, risks and benefits, and alignment of care with individual patient values and goals.

This grant aims to enhance applied regulatory science research for the evaluation and treatment of cardiotoxicity associated with oncology therapeutics. The initiative will facilitate collaboration with the FDA to develop effective methodologies and solutions, ensuring that research outcomes are directly relevant to regulatory decision-making. Key activities include regular communication with funded investigators and a focus on improving detection and management of cardiotoxicity, ultimately leading to impactful publications and presentations.

The NIH StrokeNet initiative invites applications for clinical trials and biomarker studies aimed at stroke treatment, recovery, and prevention. This funding opportunity encourages collaborative projects that validate promising interventions and scientific aims within the NIH StrokeNet framework. Key deadlines for submissions span from February 2025 to November 2026, with support provided by the National Coordinating Center and Regional Coordinating Centers to ensure efficient study implementation and participant recruitment.

The Child Well-Being Grant Program, established by the Doris Duke Foundation, focuses on promoting the healthy development of children and preventing abuse. With a commitment to addressing systemic inequities, the program supports initiatives that strengthen social service systems and foster partnerships to enhance access to services. It prioritizes funding for projects that encourage community-based interventions and the development of future leaders dedicated to improving child welfare, ensuring all children have the opportunity to thrive in safe and supportive environments.

Ethan J. Hazelwood Heart of Gold Memorial Scholarship

The Ethan J. Hazelwood Heart of Gold Memorial Scholarship was established in 2025 by family and friends of Ethan as a lasting tribute to his life and giving spirit.

Those who knew Ethan remember him as a kind, creative, and giving person. He was always helping others and once gave the boots on his feet to a fellow student who had none.

Open to individuals in Whitley and Noble County, the scholarship is for high school seniors as well as non-traditional students, who wish to pursue additional education in the field of agriculture or diesel mechanics.

Arnold Ventures

Arnold Ventures (AV) is a philanthropy dedicated to improving the lives of Americans through evidence-based policy solutions that maximize opportunity and minimize injustice. We focus on improving systems where outcomes are falling short, incentives are misaligned, and the time is right for change. To advance this mission, we invest in rigorous research to strengthen the evidence base on what works to improve outcomes for individuals, families, and communities, and to inform policy and practice at scale.

AV’s Higher Education team seeks to fund rigorous, causal research on programs, policies, and practices that improve student outcomes and deliver stronger returns on investment for students and taxpayers. Our work focuses on strengthening the evidence base on effective student success models and aligning policy and funding incentives to support their adoption and scale.

Causal Research to Improve Outcomes for Part-Time Students

Purpose of the RFP

This RFP seeks to fund rigorous causal research that builds the evidence base on effective programs and policies for part-time students and identifies scalable, cost-effective approaches to improve completion and labor market outcomes. Findings should generate actionable insights to inform institutional practice, system-level decision making, and state policy, with the goal of improving outcomes and maximizing return on investment for students and taxpayers.

Population of Interest

Because enrollment intensity is fluid, proposals do not need to limit eligibility to students who are enrolled part-time at baseline. Instead, studies should focus on interventions that primarily serve or are expected to meaningfully impact students who are more likely to enroll part-time, including:

• Adult learners (age 25+)
• Student parents and caregivers
• Working adults

Interventions may serve mixed-enrollment populations, so long as the proposed study is clearly designed to improve outcomes for these populations.

The TTP Bridge Program aims to enhance the safety and accessibility of bridges in Tribal communities, addressing the urgent need for infrastructure improvements. With aging bridges affecting economic development and children's transportation, this program allows federally recognized Indian Tribes to apply for funding for planning, construction, and rehabilitation of bridges. By focusing on TTP bridges in poor condition, the initiative seeks to strengthen economic foundations and ensure better connectivity with markets, benefiting both families and communities.

The Bayer Fund: Food & Nutrition Grant supports high-quality programs that combat malnutrition and improve access to nutritious foods, particularly for underserved communities and families with young children. Eligible organizations include 501(c)(3) nonprofits and government units. The fund prioritizes long-term behavioral change towards healthy eating and nutrition, with grants typically not exceeding 25% of an organization's operating budget. International requests start at $25,000, fostering sustainable food security and education initiatives.

The Lower Mississippi Alluvial Valley Restoration Fund RFP aims to provide grants for projects that restore and maintain bottomland hardwood forests and wetlands, enhance agricultural lands for better soil health and wildlife habitat, promote aquatic connectivity, and improve community resilience. Grants range from $150,000 to $1,000,000, depending on project scale, and applicants are encouraged to consult NFWF for proposals outside this range. This program follows an annual application cycle.

The PCC Rapid Response Grants provide support for cultural initiatives that aim to shape narratives during critical cultural moments. These grants prioritize projects that engage communities of color, immigrants, refugees, and other marginalized groups, focusing on intersectionality, gender justice, and social equity. Eligible projects include pop culture campaigns, research, and public spectacles that respond to urgent political and cultural events, aiming to reach mass audiences and disrupt harmful narratives.

The Joyce Foundation's Culture Program aims to enhance racial equity and economic mobility in the Great Lakes region by supporting underrepresented artists and organizations. Focused on Chicago, it provides multi-year general operating grants and project grants to foster creativity and cultural vibrancy. The Foundation prioritizes historically underfunded artists and encourages innovative approaches to artistic growth, ensuring diverse artistic expressions contribute to thriving communities. Note: Limited new grants are awarded annually.

Patrick Caroselli Scholarship

To provide financial assistance for college to high school seniors in Monroe County whose parents immigrated to the United States and attained citizenship.

Number and Size of Awards

Number of recipients and award amounts vary; award amount may be split between two or more recipients. Award paid in one lump sum in the Fall and divided equally between the Fall and Spring semesters. Average award $5,000; not to exceed the cost of tuition.

Allowed Use of Award

Awards must be used for costs related to enrollment in a higher education program, prioritizing tuition fees.

This funding opportunity invites applications for R01 grants focused on molecular imaging methods to explore cancer inflammation in vivo. It aims to enhance understanding of dynamic interactions between inflammation and cancer through innovative imaging techniques. The initiative encourages collaborations between cancer researchers and imaging scientists to leverage molecular imaging for identifying cellular physiology changes in response to treatment. Deadline dates for applications range from February 2025 to October 2027, emphasizing timely submission for prospective researchers.

The Integration of Imaging and Fluid-Based Tumor Monitoring in Cancer Therapy (R01 Clinical Trial Optional) aims to enhance cancer treatment by integrating imaging and liquid biopsy assays. This initiative, led by the National Cancer Institute (NCI), encourages grant applications focused on assessing therapy responses and resistance emergence in patients. Key deadlines for submissions span from February 2025 to January 2028, providing ample opportunities for researchers to contribute to this vital area of cancer research.

Jacqueline Hall Minet Travel Award for Cross-Cultural Understanding

To provide financial assistance to a Brighton High School student or a Rochester City School District high school student so that he or she can participate in a travel experience that offers significant opportunities for involvement in a foreign-language culture.

Number and Size of Awards

Number of recipients and award amounts vary; maximum $2,000.

Allowed Use of Award

Awards may be used for expenses associated with travel abroad programs.

The Leukemia Exploration and Prevention Grant Program (LEAP) aims to advance cancer interception and prevention strategies for patients with RUNX1 familial platelet disorder. This initiative, supported by the American Cancer Society, focuses on understanding the mechanisms behind leukemia development and fostering innovative research leading to effective treatment options. Grants of up to $215,000 per year for four years are available, emphasizing the urgent need for targeted therapies in high-risk populations.

The Leukemia Exploration and Prevention Grant Program (LEAP) aims to advance cancer interception and prevention for patients with RUNX1 familial platelet disorder (RUNX1-FPD). This program supports interdisciplinary research teams investigating the mechanisms of leukemogenesis and innovative treatment strategies. With funding of up to $430,000 per year, LEAP encourages projects focused on both understanding clonal evolution and developing novel therapeutic approaches. The initiative seeks to bridge critical knowledge gaps and provide urgent interventions for high-risk populations.

Dr. Jeffrey Hanson Memorial Scholarship

To support those pursuing careers in medicine, particularly primary care. 

Number and Size of Awards

One award of $2,750; paid in one lump sum in the Fall and divided equally between the Fall and Spring semesters.  

Allowed Use of Award

Awards may be used for tuition, fees, books, and other expenses associated with higher education.

The NIH is seeking innovative computational approaches to enhance the curation of biomedical research assets at scale. This initiative aims to accelerate access to secure datasets and computational models, facilitating transformative discoveries in biomedical science. Key deadlines for applications range from January 2025 to January 2027, covering standard, renewal, and AIDS-related grants. Applicants are encouraged to submit Letters of Intent 30 days prior to application deadlines to ensure a streamlined review process.

This funding opportunity invites applications for pilot projects focused on understudied proteins linked to rare diseases. The goal is to generate preliminary data and tools related to these proteins, which belong to druggable families with known rare disease associations. By supporting innovative research, this initiative aims to facilitate the characterization of these proteins, ultimately contributing to advancements in understanding and treating rare diseases.

Community Collaboration Challenge

Applications for the 2026 Community Collaboration Challenge are now open! With support from the Leon Lowenstein Foundation, the Challenge provides $5,000 – $10,000 awards to communities and is designed to support collaboration that expands and pilots evidence-based K-12 student supports in the form of high-impact tutoring, mentoring, student success coaching, postsecondary transition coaching, and/or wraparound/integrated student supports.

The Igor Gorin Memorial Award, established in 1993 by the Community Foundation for Southern Arizona, honors the legacy of Igor Gorin by supporting aspiring vocalists. With $382,000 awarded to 49 young talents, this fund provides unrestricted financial assistance for coaching, travel, and auditions. The 2026 award offers up to $12,000, aimed at those overcoming financial barriers to pursue operatic careers, ensuring that exceptional vocalists can thrive in their artistic journeys.

American College Of Sports Medicine Foundation Inc

ACSM is the largest sports medicine and exercise science organization in the world, with nearly 50,000 international, national and regional members and certified fitness professionals.

Our Mission: To educate and empower professionals to advance the science and practice of health and human performance.

GSSI Pathways in Sports Science Award | Graduate Student Research & Mentorship Award

GSSI celebrates the passion, resilience, and academic excellence of first-generation college students pursuing graduate degrees in exercise physiology, sports science, kinesiology, and/or sports nutrition. Designed to empower emerging leaders in the field, the award recognizes individuals who are breaking new ground, not only in their families but in the science of human performance.

In addition to research funding, to help promote professional development, award winners will receive one year of 1:1 mentorship from a GSSI scientist. Award winners will also receive complementary registration to ACSM’s 2027 Annual Meeting in Indianapolis, IN.

ACSM requires award winners to:   

• Submit official transcripts if selected as an award winner, 
• Attend the 2027 ACSM Annual Meeting in Indianapolis, IN. 
• Present funded research at a future ACSM Annual Meeting, and   
• Send ACSM a copy of any publications or presentations related to the funded research. 

The NIDCR Drug, Biologic, Device and/or Procedure Intervention Clinical Trial Planning and Implementation Cooperative Agreement (UG3/UH3) is designed to support clinical trial planning and implementation for dental, oral, and craniofacial conditions. This funding opportunity encourages applications that propose innovative research strategies within the NIDCR mission. Key deadlines span from February 2025 to January 2028, with emphasis on milestone-driven planning phases leading into possible clinical trial phases.

The WAEF Scholarships, supported by the Washington Apple Education Foundation, offer over $1 million in educational awards to more than 300 students this year. These scholarships are primarily for individuals with ties to the tree fruit industry in Washington, with a special focus on the Danna Gebbers Guzman Memorial Scholarship, aimed at nursing students. Eligible recipients can use the funds at accredited institutions with nursing programs.