Best Large Grants for Nonprofit Organizations in Indiana

The Autism Care Today SOS Program is dedicated to providing immediate assistance to families affected by autism across the United States. Established in 2005, this program addresses urgent needs for effective treatments and services for autism spectrum disorders. Unlike typical grant cycles that may take up to 12 weeks, the SOS Program prioritizes those in critical situations, ensuring timely support based on available funding. Eligibility includes a family income below $45,000 and a demonstrated immediate need for treatment.

The Pilot Research Grant, offered by the Society of Interventional Radiology Foundation, supports innovative research in interventional radiology to improve patient care. Grants of up to $35,000 are available for full-time faculty and post-doctorates with relevant degrees in the U.S. and Canada. Applicants must be current SIR members and can submit proposals for preliminary data generation, enhancing their chances for future funding opportunities.

The NINDS Faculty Development Award aims to enhance diversity in neuroscience research by supporting junior faculty from underrepresented backgrounds. This award provides essential research cost support, protected research time, and mentorship for individuals holding doctoral degrees within their first three years on a faculty tenure track. It specifically encourages research proposals that do not involve independent clinical trials, while allowing participation in trials led by mentors. Key application deadlines span from October 2024 to June 2027.

Kids' Chance of Massachusetts offers scholarships to children of workers who have been severely injured or killed in workplace accidents. This 501(c)(3) non-profit organization awards funds based on financial need, with applications accepted annually. Eligible students must be dependents aged 17-22, enrolled full-time in post-secondary education, and demonstrate financial need. Renewal applications are available for previous recipients who maintain satisfactory academic progress.

The High-End Instrumentation (HEI) Grant Program, offered by the NIH, invites applications for purchasing or upgrading high-end, specialized instruments, with a minimum award of $750,001 and a maximum of $2,000,000. This program supports NIH investigators aiming to enhance their research capabilities through advanced technologies such as mass spectrometers and electron microscopes. Applications must be submitted by 5:00 pm local time of the applicant organization.

The Updated National Dislocated Worker Grant Program Guidance informs workforce development systems about the policies and priorities for using National Dislocated Worker Grant funds. This guidance outlines grant types, funding approaches, performance periods, cost limitations, and application requirements. It emphasizes the critical role of DWGs in supporting economic recovery, community resilience, and equitable workforce development, ensuring that these funds effectively contribute to creating good jobs and enhancing local economies.

The DCCF: Ag Field of Interest Grants support non-profit agricultural programs aimed at enhancing knowledge and involvement in agriculture. These grants, funded by local agricultural producers, prioritize innovative projects that benefit Decatur County residents. Eligible applicants include 501(c)(3) organizations, governmental agencies, and qualified educational institutions. Projects must demonstrate community impact and cannot be for operating deficits, political activities, or religious purposes. Applications are accepted year-round, with a recommendation to apply at least 60 days prior to project commencement.

The PLTW Gateway program, backed by Ardagh Group, aims to enhance educational opportunities in local communities. Over the next decade, this initiative will support over 500,000 PreK-12 students and provide exceptional training for more than 5,000 teachers across 2,000 schools in the U.S. The program focuses on fostering innovation and creativity through engaging STEM curricula, ensuring that educational resources are accessible and effective for all students.

The Whole Foods Market Store Giving Program supports local communities by providing financial assistance to 501(c)(3) nonprofit organizations that focus on food access and environmental stewardship. This biannual program allows eligible organizations to apply via the Community Engagement Portal, although not all requests can be fulfilled due to high demand. Priority is given to those without recent funding, promoting sustainable community engagement.

The NIDCR Behavioral and Social Intervention Clinical Trial Planning and Implementation Cooperative Agreement (UG3/UH3 Clinical Trial Required) aims to support innovative research in behavioral and social interventions for dental, oral, and craniofacial conditions. This funding opportunity includes a milestone-driven planning phase of up to 2 years, with potential transition to implementation for an additional 5 years, facilitating comprehensive trial development and assessment.

The Ida Halpern Fellowship and Award, offered by the Society for Ethnomusicology, supports research on Native American music in the U.S. and Canada. Established scholars, recent Ph.D.s, and Ph.D. candidates are eligible, while previous awardees must wait three years to reapply. The fellowship includes a $4,000 grant and a $1,000 award for published research, with preference given to studies based on Dr. Halpern's Northwest Coast music collection.

Myasthenia Gravis Rare Disease Network (MGNet)

The Myasthenia Gravis Rare Disease Network (MGNet) is a consortium of academic medical centers partnering with the Myasthenia Gravis Foundation of America and Conquer MG as well as collaborators in other research groups and industry. We are working together to enhance therapeutic development for this rare disease.

Diseases Studied

Myasthenia Gravis (MG) and its subtypes:

• Early-onset acetylcholine receptor (AChR) antibody (Ab) positive MG, which primarily affects women
• Late-onset AChR Ab positive MG with a disease bias towards men
• Paraneoplastic thymoma-associated MG
• Muscle specific kinase (MuSK) Ab positive
• AChR/MuSK antibody negative MG

Goals, Mission, & Vision

The goal of MGNet is to advance therapeutic development. To do so we have four specific aims:

• Improve the tools scientists and doctors have for performing clinical trials through rigorous monitoring of patients over time and evaluate better measures of how patients are doing.
• Identify objective measures (biomarkers) to show how the disease is responding to treatment and better predict treatment response or side effects, to improve the design of clinical trials and care of patients in clinical practice.
• Enhance the education of young investigators focusing their careers on rare diseases and specifically MG.
• Improve the awareness of scientists, physicians, and the public regarding the unique needs of patients with MG through training of clinician scientists and engagement of the patient and scientific communities in clinical research and therapeutic development.

Pilot and Feasibility Grants

Objectives

MGNet, a NIH-funded Rare Diseases Clinical Research Consortium (RDCRC) in partnership with the Myasthenia Gravis Foundation of America and Conquer MG, is seeking proposals for highly innovative investigations in early stages of development.

The priorities of the Pilot Grant Program are:

• Identification treatment responsive biomarkers
• Assess clinical measures and improve that enhance clinical trial readiness
• Evaluation of therapeutic interventions for one or more of the five distinct sub-types of MG

Pilot studies must be designed to access the resources of MGNet and focused on clinical and translational research, including fulfilling the definition of clinical and translational research and exclusion of animal studies.

Funding

The MGNet expects to fund up to two grants, each at a level of $75,000 (IDCs will be limited to 10% and included in the $75,000). Projects will be funded for 12 months. Selection among the applications received will be based on the recommendations of a review committee. A grant may be renewed for an additional one year with approval of interim report by the same review process and availability of funds. Demonstration of fulfillment of initial aims and justification for additional funding will be required. The request will be required a minimum of three months prior to the initial funding period completion.

The Hasting Innovation Award for Interstitial Lung Disease, offered by the American Lung Association, provides $75,000 annually for up to two years to support early-career researchers. This award targets investigators with proven excellence and a track record of accomplishment, aiming to advance lung disease science. Successful candidates must have held a K or R type award within the last three to five years, fostering innovation and discovery in lung health.

The NCI Continuing Umbrella of Research Experiences (CURE) Non-Mentored Research Scientist Career Development Award (K22) aims to support postdoctoral fellows from underrepresented backgrounds in transitioning to tenure-track positions. This award provides essential funding for salary and research support for three years, enabling candidates to establish independent biomedical careers. Key deadlines for applications range from February 2025 to October 2027, ensuring ample opportunity for eligible researchers to secure funding for their career development.

The AO Spine NA Young Investigator Research Grant Award supports early-career surgeons and researchers focusing on clinically relevant spinal or spinal cord research. With funding of $20,000, this initiative encourages new investigators by providing essential start-up capital. Successful applicants are required to present their findings at the Annual AO Spine North America Fellows Forum and submit progress and final reports detailing their research outcomes. This grant aims to foster innovation and excellence in spinal care.

The Bottomley, Peter R. Scholarship Fund, managed by the Noble County Community Foundation, offers a scholarship to an East Noble High School senior who has participated in the school band for four years and is pursuing a four-year degree in instrumental music education or performance. Applicants must maintain a minimum GPA of 3.00. This initiative aims to support aspiring musicians in their educational journey and further enrich the community's cultural landscape.

The NIH StrokeNet initiative invites applications for multi-site exploratory and confirmatory clinical trials targeting interventions for stroke prevention, treatment, and recovery. This includes biomarker validation studies and ancillary studies to enhance active research. Successful applicants will collaborate within the NIH StrokeNet framework, with support from the National Coordinating Center and Data Management Center to ensure efficient study implementation and robust statistical analysis. Key deadlines for application submissions span from March 2024 to November 2026.

The NCCIH Natural Product Mid Phase Clinical Trial (R01 Clinical Trial Required) grant invites applications for mid-phase clinical trials focusing on natural products such as botanicals and dietary supplements. It aims to advance scientific knowledge by determining optimal dosing and patient responses. Applicants must provide preliminary data demonstrating bioavailability and measurable impacts on target engagement. This initiative will not support efficacy trials for cancer treatments and encourages early contact with NCCIH scientific contacts.

The Bayer Fund: Food & Nutrition Grant supports high-quality programs that combat malnutrition and improve access to nutritious foods, particularly for underserved communities and families with young children. Eligible organizations include 501(c)(3) nonprofits and government units. The fund prioritizes long-term behavioral change towards healthy eating and nutrition, with grants typically not exceeding 25% of an organization's operating budget. International requests start at $25,000, fostering sustainable food security and education initiatives.

The NCCIH Natural Product Early Phase Clinical Trial Award supports innovative clinical trials of natural products, such as botanicals and dietary supplements, with a strong scientific basis. Applications are encouraged to explore optimal delivery methods and combinations with other treatments. Funding is available for up to three years to assess the impact on target engagement and clinical outcomes, aiming to translate basic science findings into practical clinical applications.

The Lawrence A. Taylor Research Fund in Petrology and Geochemistry offers financial support to two PhD students demonstrating outstanding research in Petrology and/or Geochemistry. Funded by Dong-Hwa Shin (Dawn) Taylor, this grant aims to alleviate some financial burdens associated with their doctoral studies, fostering excellence in these critical fields. Eligible candidates must be AGU student members currently enrolled in relevant doctoral programs and engaged in applicable research.

The American Occupational Therapy Foundation's AOTF Intervention Research Grant Program supports innovative research in occupational therapy, providing up to $100,000 for projects that address health inequities and social justice. This initiative aims to generate preliminary data essential for larger studies, aligning with the profession's Vision 2025. By focusing on underrepresented populations, the program encourages inclusivity and ethical research practices, ensuring a diverse study population. This funding opportunity is crucial for advancing evidence-based practices in occupational therapy.

Karma for Cara Microgrants empowers students aged 18 and under to bring their service project ideas to life with funding up to $1,000. Founded in honor of Cara Becker, who inspired community service during her own health journey, the program supports a wide range of initiatives aimed at improving local communities across the U.S. Students are encouraged to demonstrate creativity and community involvement, with grants awarded quarterly to fuel their impactful projects.

The Classics for Kids Matching Grant Program, established by the Classics for Kids Foundation, aims to enhance music education for at-risk and rural youth by providing matching grants for fine stringed instruments. Since 1998, over $2 million has been allocated to support more than 300 programs across all 50 states. Schools and non-profits demonstrating need and commitment are encouraged to apply, fostering lifelong benefits of music participation and education.

The PCC Rapid Response Grants provide support for cultural initiatives that aim to shape narratives during critical cultural moments. These grants prioritize projects that engage communities of color, immigrants, refugees, and other marginalized groups, focusing on intersectionality, gender justice, and social equity. Eligible projects include pop culture campaigns, research, and public spectacles that respond to urgent political and cultural events, aiming to reach mass audiences and disrupt harmful narratives.

The Arthritis National Research Foundation (ANRF) offers grants for research focused on Psoriatic Arthritis (PsA). With funding of up to $125,000 over two years, the ANRF encourages innovative projects that reveal the underlying mechanisms of PsA. Eligibility includes M.D. or Ph.D. qualifications and affiliation with a U.S. nonprofit research institution. Preference is given to senior post-doctoral researchers transitioning to independent status and new assistant professors. Applications without a Co-PI or those who have previously received ANRF funding will not be accepted.

The Prader-Willi Syndrome Mini-Fellowship Grant aims to enhance understanding of Prader-Willi Syndrome (PWS) through clinical proctorships. Offering up to $25,000 USD, this grant supports providers in shadowing experts in PWS while engaging in an academic project. PWSA | USA, dedicated to advancing research since 1983, focuses on high-impact projects that translate biomedical knowledge into effective treatments, ultimately improving the lives of those affected by PWS.