Best Large Grants for Nonprofit Organizations in Indiana

The Society of the Order of the Southern Cross Grant aims to support charitable projects that preserve and restore Southern heritage artifacts and locations. Eligible projects may include military artifacts, monuments, and historical sites. Organizations typically need to secure 50% of necessary funding before applying. The Order encourages discussions for projects that may not meet standard funding levels, emphasizing their commitment to preserving cultural heritage.

The Detroit Economic Club Scholarship Program provides financial assistance to students from Detroit and surrounding counties pursuing undergraduate education. Each year, two renewable scholarships of $2,000 are awarded to incoming college freshmen. Recipients can reapply for up to three additional years. The program is supported by the Detroit Economic Club Education Endowment Fund, dedicated to helping local students achieve their educational goals. For more information, visit the FAQs on the Community Foundation for Southeast Michigan's website.

The FY26 Orthopaedic Research Program Clinical Research Award supports vital clinical research addressing orthopaedic-specific factors and interventions. It aims to generate evidence that optimizes patient outcomes and informs clinical care, benefiting Service Members, Veterans, and the public. Applications should focus on priority areas such as Ligamentous Trauma and Military Women’s Health, ensuring significant impact on patient care and mitigation of orthopaedic injuries.

Community Foundation of the North State

The Community Foundation builds trust through relationship, integrity, and by providing safe places for donors to give their resources.

We are a nonprofit, public charity serving the people of Shasta, Siskiyou and Tehama counties, with a mission to impact the region through the power of giving.

Scholarships

The Community Foundation of the North State manages many scholarship funds that are awarded to graduating high school seniors as well as students already in an undergraduate program. Some scholarships were started by families or individuals; others by businesses or organizations. All scholarships share one important focus: helping young people reach their educational goals.

Don & Debbie Bankson Scholarship Endowment Fund

This opportunity allows the donors to fulfill their desire to help Shasta County youth, with excellent academics and a strong community-service background, pursue a college education.

Don and Debbie Bankson are longtime residents of Shasta County with a passion to support the community they love. Through a donation of real property to the Shasta Regional Community Real Estate Foundation, the Banksons seeded the Don and Debbie Scholarship Fund to fulfill their desire to help Shasta County youth, with excellent academics and a strong community-service background, pursue a college education.

The DoW Orthopaedic Applied Research Award supports innovative research aimed at improving treatment and functionality for individuals with combat-related orthopaedic injuries. Applicants are required to present preliminary data and focus on applied research that evaluates new solutions, including pharmacologic agents and rehabilitation techniques. This initiative emphasizes the importance of military relevance, aiming to benefit Service Members, their families, and Veterans, while clinical research proposals are not permitted.

The Cheryl Wojtas Memorial Scholarship Program honors Cheryl Wojtas's commitment to education by offering scholarships to deserving graduates from Port Huron Area Schools and Gaylord Community Schools. Each recipient will receive a one-time award for their freshman year at a nonprofit post-secondary institution, aimed at supporting their educational journey. Financial need is a key consideration, and funds will cover tuition, fees, and essential expenses related to their studies.

OREF/Musculoskeletal Transplant Foundation Research Grant

Solicits investigator-initiated proposals focusing on research in the science of biologic – reconstruction, bone regeneration, transplantation - allografts, and including stem cells for graft transplantation.

The Petco Love Foundation, previously known as the Petco Foundation, has been dedicated to animal welfare since 1999. With a mission to enhance the lives of pets and their families, they provide significant funding to nonprofit organizations for lifesaving initiatives. The 'Access to Care' program supports spay/neuter clinics and low-cost veterinary services, ensuring that more pets receive essential care. Petco Love remains committed to fostering healthier communities and improving the well-being of pets across the nation.

Community Foundation of the North State

The Community Foundation builds trust through relationship, integrity, and by providing safe places for donors to give their resources.

We are a nonprofit, public charity serving the people of Shasta, Siskiyou and Tehama counties, with a mission to impact the region through the power of giving.

Scholarships

The Community Foundation of the North State manages many scholarship funds that are awarded to graduating high school seniors as well as students already in an undergraduate program. Some scholarships were started by families or individuals; others by businesses or organizations. All scholarships share one important focus: helping young people reach their educational goals.

Columbia Bank Kenneth R. Gifford, Jr. Memorial Scholarship Program

The Columbia Bank Kenneth R. Gifford, Jr. Memorial Scholarship Program (formerly Columbia Bank) awards ten, $1,000.00 scholarships each year. High school seniors attending school in Siskiyou, Shasta, Tehama, Glenn, Colusa, Placer, Sacramento counties may apply.

Columbia Bank recognizes that our continued success is contingent upon the health and vitality of the communities we serve. Taking action to improve the well-being of others is a community responsibility and commitment we fully believe in and commit to. We value the opportunity to provide financial support to the youth in our communities.

Patrick J. Kiley / Houston AGC Scholarship

Benefiting employees, dependents of employees, and/or interns of AGC Houston member firms OR students involved in AGC Student Chapters.

Award Amounts

Multiple awards are given each year. Scholarship award amounts will vary for each selected scholarship recipient.

The Foellinger Foundation Nonprofit Staff Leadership Award honors exemplary leadership among nonprofit staff members from organizations funded by the foundation in the past five years. One recipient will receive a $3,000 grant for professional development opportunities, including training and certifications. The award emphasizes adaptive leadership, organizational culture, community engagement, and professional growth, aiming to recognize individuals who drive impactful change within their organizations and communities.

Our Mission

We strengthen our community for current and future generations by helping people make a difference in the lives of all.

We believe in our community’s lasting goodness. In fact, making sure our community is always a special place for us to live is why we’re here.

Scholarships

Through the generosity of our donors, we have more than $2 million in scholarships available in 2025 to students from more than 60 high schools. We offer scholarships to high school seniors, college and nontraditional students, and K-12 art and music camps and lessons.

The Academy Martial Arts Leadership Scholarship

Background

The Academy Martial Arts Leadership has been serving families in the Fox Cities since 1995. As the founders/owners, Jeff & Amanda Denu have been passionate about making our community stronger one Black Belt at a time teaching martial arts, while reinforcing respect, self-discipline, integrity, and excellence. Their passion with community involvement and creating a positive learning environment inspires others to be their personal best, and to make a difference every day.

Pediatric Hidradenitis Suppurativa Challenge Grant

Hidradenitis suppurativa (HS) is a devastating chronic inflammatory disease that manifests as recurrent painful nodules under the skin in the intertriginous areas of the body. It is associated with significant impacts on quality of life, psychosocial well-being, and long-term health outcomes of patients as well as consequences for families and caregivers. HS is prevalent, affecting between 1 and 4% of the population beginning in adolescence and persisting into adulthood. Despite the impact of HS, it remains underdiagnosed, undertreated, and understudied particularly in the pediatric and adolescent populations. Contributing to this dynamic are unknowns related to a complex disease etiology, stigma associated with HS symptoms (e.g., sweating, itching, and scarring commonly in the genital region), and limited treatment options to date with even fewer available for children under the age of 12.

To address the needs of children and adolescents living with HS, the Pediatric Dermatology Research Alliance (PeDRA), HS Connect, and the HS Foundation are offering the 2026 Pediatric HS Challenge Grant to support an early-to-mid career investigator for a one-year project focused on a high-priority, patient-centric research topic.

Focus

Proposals should address one or more of the following high-priority research topics:

• Predicting treatment effectiveness and risk utilizing real world evidence and/or experience
• Early disease and factors involved in severe disease development
• Optimizing surgical and procedural approaches to minimize pain, shorten healing time, and reduce recurrence
• Improving recruitment of diverse and representative populations for clinical studies, trials and advanced therapeutics

Funding:

• Up to $50,000 to support one year of research
• One award anticipated for this funding cycle

The NATA Foundation's Professional Grants Program - New Investigator Grant offers up to $20,000 in funding for innovative research projects in athletic training. This program is aimed at supporting new investigators who are NATA members and BOC certified athletic trainers. The grant fosters research that enhances the profession and contributes to the health and safety of physically active individuals, promoting evidence-based practices in athletic training.

The Innovations in Graduate Education (IGE) Program, funded by the National Science Foundation, aims to transform STEM graduate education through innovative training approaches. It encourages proposals that support skill development for STEM careers and research on effective educational systems. The program offers funding for projects that pilot and validate novel educational models, promoting broad participation and collaboration with various sectors. Awards range from $300,000 to $1,000,000, depending on the track and project duration.

Community Foundation of the Holland/Zeeland Area

Our Mission

The Community Foundation of the Holland/Zeeland Area seeks to ensure that our community thrives today, tomorrow, and forever by building our Community’s Endowment to support high impact charitable projects, helping donors achieve their charitable goals, and leading and partnering in community-level initiatives.

Scholarships

CFHZ awards over $1 million in scholarships each year for students to attend schools of higher education throughout the nation. Our scholarships are possible thanks to the generosity of donors who invest in our community’s future by furthering the education of others.

All Holland/Zeeland area individuals interested in post-secondary education are encouraged to apply for CFHZ scholarships.

The Foundation proudly administers over 100 scholarships, each with unique eligibility criteria that must be met before a candidate can be considered.

Neydon Scholarship for the Children of Widows

• Graduating senior from one of the following high schools: Black River, Holland Christian, Holland High School, West Ottawa, Zeeland East, or Zeeland West
• Enrolling at an accredited post-secondary school within the United States
• Financial need (must submit the page of the FAFSA Submission Summary showing the Student Aid Index amount)
• Child of a widowed mother
• Preference given to those students who are not selected to receive other types of scholarships, particularly full scholarships

Taka Domingo HLP Vocational Scholarship

The HLP Hamakua Community Foundation is a non-profit organization that was formed to benefit the people of Hamakua. Taka Domingo was one of the original board members when HLP was established after the closure of sugar. He was an electrician and County Councilman representing the Hamakua District. The Taka Domingo HLP Vocational Scholarship was established after his death in August 2016. 

Individual award amount: $2,000. 

Possible trades include: welding, tourism, fire science, electrical, early childhood education, agriculture, auto body, auto mechanics, diesel mechanics, carpentry, culinary and others not listed.

This grant aims to address drug shortages by exploring the landscape of products susceptible to health fraud and finding ways for outsourcing facilities to fulfill these needs. By funding research and development, the initiative seeks to enhance the production of critical medications, thereby stabilizing the drug supply chain and protecting public health from fraud-related risks.

The KONG Toy Grant, offered by the Petfinder Foundation in collaboration with KONG, aims to enhance the adoptability of shelter pets by providing enriching toys. This initiative supports animal shelters and adopters throughout North America, helping to keep pets mentally stimulated and happy. By focusing on pet enrichment, the grant seeks to increase the chances of successful adoptions, thereby reducing the euthanasia of adoptable animals. Organizations that are Petfinder.com members can apply for these valuable resources.

Community Foundation of the Holland/Zeeland Area

Our Mission

The Community Foundation of the Holland/Zeeland Area seeks to ensure that our community thrives today, tomorrow, and forever by building our Community’s Endowment to support high impact charitable projects, helping donors achieve their charitable goals, and leading and partnering in community-level initiatives.

Scholarships

CFHZ awards over $1 million in scholarships each year for students to attend schools of higher education throughout the nation. Our scholarships are possible thanks to the generosity of donors who invest in our community’s future by furthering the education of others.

All Holland/Zeeland area individuals interested in post-secondary education are encouraged to apply for CFHZ scholarships.

The Foundation proudly administers over 100 scholarships, each with unique eligibility criteria that must be met before a candidate can be considered.

Shelley Speet-Mills Creative Arts Scholarship

• Graduating senior or graduating early college student who attends public, private, or home school in the primary service area of the Community Foundation
• Enrolling at an accredited post-secondary school within the United States
• Financial need (must submit the page of the FAFSA Submission Summary showing the Student Aid Index amount)
• GPA of 3.0 or greater
• Planning to pursue a career in the arts
• Recommended by applicant’s high school art teacher
• This scholarship is potentially renewable and supports one student at a time. 

The ACVO Vision for Animals Foundation provides research grants of up to $7,500 annually to residents in ABVO-approved veterinary ophthalmology programs. Funding covers research supplies, publication costs, and limited travel expenses. Eligibility requires mentorship by an ABVO-approved faculty member and Institutional Animal Care and Use Committee approval for animal-related experiments. Funded research results must be presented at the Annual ACVO Conference. Note that salaries and major equipment costs are not supported.

Our Story

The IBMA Foundation was created by the International Bluegrass Music Association in 2007 with a bequest from the Richard Barnhart estate. Mr. Barnhart was a musician from northern Virginia who loved bluegrass and wanted to support educational programs for children. Since the beginning, our goal has been to support bluegrass-music-related educational, literary, artistic and historic preservation activities.

In our early years we produced Discover Bluegrass, an educational video that has been used in thousands of classrooms and libraries around the world. We have hosted dozens of teacher workshops and artist trainings. We created a bluegrass lesson plan competition and provided a network for leaders of after-school bluegrass programs.

Our project grants, which now total $25,000 a year, support bluegrass-related initiatives throughout the world. We also fund Bluegrass in the Schools Mini-grants ($7,000/year) which help schools to hire bluegrass bands for school programs. The Rosenberg Bluegrass Scholar Award recognizes excellence in academic research. Six college scholarships are granted for students working in various areas of the bluegrass music industry. The Arnold Shultz Fund supports increased participation of people of color in bluegrass music with grants that total $30,000/ year. Fletcher Bright Memorial Grants for Young Musicians (age 18 and younger) help young people go to bluegrass music camps and workshops, take lessons, and purchase educational materials.

The Sally Ann Forrester Scholarship

The Sally Ann Forrester College Scholarship is a $1,000 – $2,000 scholarship awarded to a female bluegrass musician. Students may be majoring in any subject, including bluegrass music. The IBMA Foundation administers the scholarship, which is funded by an endowment at the Community Foundation of Middle Tennessee. Sally Ann Forrester played accordion and sang as a member of Bill Monroe and His Blue Grass Boys from 1943-1946, thus becoming the first female professional bluegrass musician in history.

Community Foundations of the Hudson Valley 

Community Foundations of the Hudson Valley (CFHV) empowers individuals, families, businesses, and organizations to fulfill their philanthropic goals through the establishment of charitable funds that support the needs of Dutchess, Putnam and Ulster counties. With over $100 million in assets, CFHV manages nearly 600 charitable funds and has distributed more than $777 million in grants and scholarships since January 2000. We lead initiatives to address urgent community needs such as food insecurity and educational challenges, offering both immediate relief and long-term support.

Maria E. McCarthy Ringwood Memorial Scholarship

Established by the family of Maria McCarthy Ringwood to honor her memory and love of theater, this scholarship is available to Roy C. Ketcham High School and Our Lady of Lourdes High School college-bound graduating seniors who have actively participated in theater in school.

Type of Award

One-time scholarship payable to school

Current High School

Our Lady of Lourdes High School, Roy C. Ketcham High School

The Diana Jo Dreyer Memorial Scholarship, established by INDATEL Services LLC and the family of Diana Jo Dreyer, supports female students pursuing a business degree. This scholarship honors Diana's impactful career in telecommunications and her dedication to empowering women in the industry. Applicants must be graduating high school seniors, U.S. citizens, sponsored by an NTCA member, and interested in returning to rural communities after graduation. This initiative enriches the lives of young women in rural America.

The Cyberinfrastructure for Sustained Scientific Innovation (CSSI) program by the National Science Foundation aims to provide flexible funding opportunities to address evolving needs in cyberinfrastructure. It supports various award classes, including Elements for small groups, Framework Implementations for larger interdisciplinary teams, and Transition to Sustainability for established CI projects. These initiatives focus on developing integrated CI services, ensuring sustainable impact, and promoting collaboration across scientific disciplines to enhance research and innovation.

The NAPB Borlaug Undergraduate Scholars program, established by the National Association of Plant Breeders, aims to cultivate future leaders in plant breeding. Open to undergraduates in relevant disciplines, the program provides mentorship opportunities and financial support for travel to the NAPB Annual Meeting. Those eligible must be current undergraduates and may not have received similar scholarships previously. This initiative fosters professional development and engagement in the field of plant improvement.

Bill Boehlke Scholarship

Bill Boehlke worked for both the Seattle Seahawks and Seattle SuperSonics as a creative member of their digital communications departments. His imagination, humor and positive personality were appreciated by everyone he worked with. In memory of Bill, his family established this scholarship fund in 2020. The fund will provide scholarships to high school seniors in the state of Washington who are pursuing a career in digital communications, including social media video production. Scholarships will help cover qualified expenses including tuition, books and other expenses necessary for their classes. Scholarships are not renewable. Special consideration will be given to students based on financial needs and the applicant’s history of good character and community service.

Amount:

$1,000 - $5,000