Best Large Grants for Nonprofit Organizations in Indiana

The Indian Housing Block Grant Competitive Program (IHBG-COMP) for FY 2026 offers competitive grants to eligible recipients under NAHASDA. This program aims to support affordable housing initiatives benefiting low-income Tribal families, enhancing their living conditions and community well-being. Funded by the US HUD's Office of Public and Indian Housing, the IHBG-COMP encourages the development of sustainable housing solutions within Native American communities.

The Heiser Program for Research in Leprosy, established by Dr. Victor G. Heiser, focuses on innovative biomedical research to combat leprosy. Since 1975, it has funded over 200 grants totaling more than $20 million, supporting early-career researchers and significant projects. The program aims to enhance diagnostic tools, improve treatments, and implement effective surveillance strategies. With a dedicated Scientific Advisory Committee, it ensures rigorous proposal reviews and fosters collaboration among grantees, ultimately advancing leprosy elimination efforts.

The Leonard Litz LGBTQ+ Foundation, via its TransPLUS Resource Center, supports transgender, gender-nonconforming, non-binary, and intersex individuals. By providing grants and resources, the Foundation aims to address urgent needs in healthcare, housing, and legal services while fostering community connections. They build peer-support networks, publish updates, and support initiatives to empower TGNCNBI individuals and their allies, ensuring that marginalized voices are heard and uplifted.

The Louis Stokes Alliances for Minority Participation (LSAMP) Bridge to Doctorate Scholars Program, funded by the National Science Foundation, aims to recruit and retain minority graduate students in STEM fields. This program offers significant benefits, including a $32,000 annual stipend and $12,000 educational allowance for two years, fostering a supportive community through monthly dinners for Indigenous graduate students. Eligible applicants must be U.S. citizens, identify as American Indian or Alaska Native, and have participated in an LSAMP program.

The Jennie K. Scaife Charitable Foundation Grant focuses on enhancing family support, women's and children's health, and animal welfare. It aims to fund programs that promote beneficial human-animal interactions and early intervention in addiction prevention. Eligible organizations must have a valid 501(c)(3) designation. Grants align with at least one of the foundation's focus areas, ensuring impactful contributions to community welfare and well-being.

Hogg Foundation for Mental Health

The Hogg Foundation for Mental Health was established in 1940 at The University of Texas at Austin by the children of Texas Governor James Hogg. For over a quarter of a century, the Hogg Foundation was guided by the passion and insight of the Governor’s daughter, Miss Ima Hogg, who actively promoted the foundation and encouraged its staff to pursue a bold, new vision. Today the Hogg Foundation is based at The University of Texas at Austin Steve Hicks School of Social Work and is funded through an endowment created by gifts from the Hogg family and managed by The University of Texas/Texas A&M Investment Management Company.

The Hogg Foundation is inspired by Ima Hogg’s vision for a Texas that supports and promotes mental health, resilience, and well-being. Miss Ima was ahead of her time in believing that mental health was just as important as physical health. She believed all people should have access to community-based resources to support mental well-being and live fulfilling lives, and she championed supports in everyday environments like schools, workplaces, places of worship, and homes.

Stephany June Bryan: Bold Spirit of Achievement Scholarship

The Hogg Foundation for Mental Health is offering ten $5,000 scholarships in honor of Stephany June Bryan to individuals facing personal and financial barriers to achieving their educational or career goals due to the impact of living with a mental health challenge and/or supporting a loved one with a mental health challenge.

You do not need to be enrolled in a program at the time you submit your application. However, you will need to provide enrollment verification and/or a certificate of completion when/if it is awarded.

The Herbek Humanitarian Award honors a CAP member pathologist for significant contributions to the See, Test & Treat® program, which offers free cancer screenings to underserved women. Established in 2011, it commemorates Gene N. Herbek, MD, FCAP, who pioneered this initiative for Native Americans. Nominees must have led or significantly contributed to the program, with submissions due by May 3, 2024. Self-nominations or incomplete entries will not be accepted, ensuring high standards in recognition.

The Fash Foundation Grants aim to support and enhance children's education and the arts in Tarrant County, Texas. The Foundation prioritizes contributions to higher education institutions that align with its mission statement. Grants are awarded to initiatives that promote health and educational advancements in various disciplines including sciences and the arts. The Foundation seeks to foster a nurturing environment for children's educational growth.

The Environmental Engineering and Science Foundation offers six Master's Degree scholarships of $2,500 each for students pursuing advanced studies in Environmental Engineering or related fields. Eligible candidates must be U.S. citizens or permanent residents, have a strong academic record with a minimum GPA of 3.0, and be accepted into an accredited graduate program. This initiative aims to support future leaders in environmental engineering and science.

The Master's Degree Scholarship Program for Under-Represented Minority Students, offered by the Environmental Engineering and Science Foundation, provides three scholarships of $2,500 each. These scholarships aim to support students from diverse backgrounds who are pursuing a Master's Degree in Environmental Engineering or a related field. Applicants must demonstrate academic excellence with a minimum GPA of 3.0 and must identify as part of specific under-represented groups.

The Conservation Alliance Grants program is currently under evaluation, leading to a pause in the member-directed grant cycle as the organization aligns its funding with its strategic plan launching in 2025. This initiative aims to harness the collective efforts of businesses and outdoor communities to protect North America's wild places through impactful and efficient grant-making. Future funding will focus on projects that enhance habitat, support Indigenous initiatives, and address climate change.

The Rotary Works Foundation Grant supports charitable projects primarily focused on children, youth, and families, emphasizing active Rotarian involvement. Grants range from $500 to $5,000, awarded prior to events. Eligible applicants include 501(c)(3) or 501(c)(1) organizations. Preference is given to projects engaging Rotarians. The application deadline is the 2nd Wednesday of each month, and all grantees must report outcomes post-project.

The Big 33 Academic Scholarship Fund, managed by The Foundation for Enhancing Communities, offers financial assistance to Pennsylvania high school seniors planning to pursue higher education. Eligible students must maintain a minimum GPA of 2.0 and demonstrate academic achievement, community service, and leadership. Since its inception in 1985, the fund has awarded over $3.9 million in scholarships, helping countless students achieve their academic goals and overcome obstacles.

The John D. Dixon and Louise A. Dixon Memorial Scholarship Fund honors the legacy of its namesakes by supporting graduating seniors from Cedar Cliff and Northern York High Schools. This scholarship aims to assist students with a minimum GPA of 2.5 who demonstrate financial need and a commitment to volunteerism or extracurricular activities. It is a one-time award intended to help students pursue higher education at colleges or technical schools.

The Mercer Vu Farms/Ron and Judy Hissong Scholarship for Agriculture Fund honors Ron Hissong, a dedicated dairy farmer. Established by his family, this scholarship supports students from the Tuscarora School District pursuing education in agriculture or related fields, ensuring they can continue Ron's legacy of community contribution. Applicants must demonstrate financial need and a commitment to agriculture, making this opportunity vital for aspiring agricultural professionals.

The Hypercholesterolemia Grant by the Patient Advocate Foundation offers financial assistance to individuals diagnosed with hypercholesterolemia, helping cover out-of-pocket healthcare costs such as medication copays and insurance premiums. This nonprofit aims to improve patient access to necessary care while supporting over 3.8 million patients since its inception. Eligible applicants must have health insurance and meet specific income requirements to receive assistance in managing their healthcare expenses effectively.

The ScotiaRISE initiative by Scotiabank aims to foster economic resilience among disadvantaged groups over ten years, with a budget of $500 million. By focusing on enhancing educational opportunities, facilitating employment for newcomers, and removing barriers to career advancement, ScotiaRISE seeks to create a more inclusive society. This program highlights the importance of collective efforts in supporting individuals and communities to thrive, ensuring everyone has the chance to rise above challenges and contribute positively to their environments.

The Les Paul Foundation Grant supports innovative music education and medical research related to hearing loss. Eligible organizations must be U.S.-based public charities under 501(c)(3) and avoid religious, political, labor, or business affiliations. The foundation prioritizes projects that enhance music production, performance, and STEM/STEAM initiatives, particularly those benefiting individuals in challenging situations. Proposals must detail how they will share Les Paul's legacy in their work.

The Alkermes Pathways Research Awards program aims to foster research in neuroscience, specifically targeting schizophrenia and bipolar disorder. With grants up to $100,000, it supports early-career investigators exploring critical areas, including sleep and circadian disturbances related to these conditions. This initiative addresses the urgent need for innovative solutions in mental health research, empowering the next generation of scientists to make impactful contributions in understanding and treating these complex disorders.

The ABPN Dorthea Juul, PhD, Education Research Award offers up to $100,000 for research projects aligned with the ABPN's mission of enhancing lifelong learning and certification standards for psychiatrists and neurologists. Two awards each in psychiatry and neurology are available annually, with projects lasting up to two years. Eligible applicants must hold faculty appointments or have confirmed offers, comply with conflict of interest policies, and, if MDs or DOs, maintain ABPN certification and licensure.

The Sundance Collab's Cultural Impact Residency, honoring Michael Latt, is a six-month online program supporting early-career, underrepresented storytellers focused on social impact. Running from March to August 2026, it offers mentorship, feedback sessions, and resources to eight selected fellows in screenwriting, directing, and documentary filmmaking. This opportunity is designed for works-in-progress, fostering a supportive creative community to inspire and develop impactful narratives.

The NIDCD Research Career Enhancement Award for Established Investigators (K18) supports seasoned researchers in enhancing or redirecting their research through new skills acquisition. This funding opportunity addresses critical questions in hearing, balance, smell, taste, voice, speech, and language sciences. Key deadlines for applications span from June 2024 to February 2027, ensuring ample opportunity for researchers to apply and contribute to these vital fields.

The NIDCD Research Career Enhancement Award for Established Investigators (K18) program supports established researchers in enhancing their skills and redirecting their research towards critical areas such as hearing, balance, smell, taste, voice, speech, and language sciences. This program is crucial for fostering innovation and advancing the understanding of these fields. Important deadlines for applications include June 10, 2024, and October 8, 2024, among others.

The NRF Foundation Retail Management Scholarship, in partnership with CVS Health, is designed to inspire undergraduate students to pursue careers in retail leadership. Eligible candidates can receive a $10,000 scholarship and attend the NRF Foundation Student Program in NYC in January 2026. This program provides networking opportunities with top retail executives and recruiters, along with insights into career pathways in the retail industry, making it a valuable experience for aspiring leaders.

The Robert B. Taylor Fund, managed by the San Antonio Area Foundation, supports students pursuing higher education in vocational fields or those seeking associate degrees. Available to high school seniors, college students, and adult learners, it emphasizes financial need and academic performance, specifically a minimum GPA of 2.5. Preference is given to Black or African American students and those enrolled in Alamo Community Colleges. This fund aims to enhance educational opportunities and community growth.

The Child Neurology Foundation offers a Summer Scholarship for first, second, or third-year medical students interested in neurodevelopmental disabilities or child neurology. This scholarship provides $3,500 for clinical research focused on neurodevelopmental disabilities in children or young adults, conducted under the supervision of a qualified subspecialist. Applications are evaluated based on their importance, originality, and contribution to the medical student's development.

The Teresa and David R. Schmidt, M.D. Scholarship Fund, managed by the San Antonio Area Foundation, supports high school seniors pursuing careers in the medical field. Eligible applicants must demonstrate financial need and maintain full-time enrollment at accredited institutions. This renewable scholarship assists with tuition, fees, and books for students from specific Texas counties, fostering community growth and educational opportunities in healthcare since 1964.