Best Unrestricted Grants for Nonprofits in Iowa

Who We Are

Community foundations began nationally in 1914 and are publicly-supported, 501(c)(3) philanthropic organizations that hold, administer, invest and make grants from both endowed and non-endowed funds established by individuals, families and others. They were designed to be simple, flexible, convenient, tax-wise, cost-effective and perpetual charitable vehicles.  

Our Community Foundation was established in Roanoke in 1988. With our growth, we expanded into the Martinsville/Henry County area in 2005. Today, we administer many hundreds of named endowment funds ranging in size from a minimum of $10,000 to millions of dollars. To date, donors have also committed very significant resources to the Foundation through future estate gifts.

Information for Scholarship Seekers

Community Foundation Serving Western Virginia, the region’s community foundation, administers a variety of scholarships to reward and assist capable and deserving students based on the criteria established by the fund donors.

Specifics of the Foundation’s scholarship program may be subject to change from time to time. If you have any questions or need additional information, please contact the Foundation at (276) 656-6223.

Ashby C. and John T. Pinkard Scholarship Fund

 Fund provides higher education scholarships to deserving young men and women.

The FSF Case Study Scholarship invites talented fashion students to tackle real-world challenges in the industry. Open to full-time students at U.S. four-year colleges, this annual scholarship provides funding for educational expenses, mentorship opportunities, and access to internships. Recipients also enjoy invitations to the prestigious FSF Awards Gala in New York City. With a focus on supporting diverse backgrounds, this scholarship encourages all aspiring fashion professionals to apply and advance their careers.

Agog Open Call: Climate Futures + Immersive Media

This open call supports immersive media projects that help people better understand and respond to climate challenges and imagine what a better world could be.

We are looking for projects that use immersive technologies—including smart glasses, augmented reality, spatial sound, and mixed reality—to create more engaging, experiential forms of climate storytelling and civic participation.

The open call will support projects across a range of stages and formats, from early ideas to more developed work. What matters most is a compelling story or experience, a clear sense of purpose, and a thoughtful approach to bringing the work to life.

Grants may be awarded in denominations ranging from $25,000 to $200,000. In addition to funding, selected projects may receive mentorship, advisor support, and opportunities for partnership and distribution.

The Mary Kay Owens Memorial Fund, managed by the San Antonio Area Foundation, supports high school seniors from Bexar County pursuing education in physical therapy. This fund aims to assist students actively participating in varsity athletics who require financial aid to attend college. Established to make a meaningful impact, the foundation has been providing grants and scholarships since 1964, enhancing the quality of life in the San Antonio community.

About Pfizer Grants

Pfizer supports the global healthcare community’s independent initiatives (e.g., research, quality improvement or education) to improve patient outcomes in areas of unmet medical need that are aligned with Pfizer’s medical and/or scientific strategies.

Pre-clinical Investigation of anti-TFPI-mediated Rebalancing Mechanisms in Non-Hemophilic Bleeding Disorders

There remains a scientific gap in understanding of the role of anti-TFPImediated hemostatic rebalancing in the context of inherited or non-hemophilic bleeding disorders. This competitive grant program encourages competitive submissions focsed on generating preclinical/foundational data exploring the therapeutic potential and mechanisms of TFPI modulation in bleeding disorders other than hemophilia.

Project Types and Area of Interest

Potential applicants are encouraged to identify and address preclinical/basic science data generation for TFPI modulation/rebalancing in their local setting. This may include:

• Rare bleeding disorders which arise from deficiencies in different clotting factors or pathway components but converge on a common functional endpoint which is an impaired thrombin generation (e.g., Factor II, Factor V, Factor VII, Factor X and Factor XI deficiencies, as well as von Willebrand disease).
• Other diseases such as Glanzmann's thrombasthenia (GT) that have a distinct pathophysiological mechanism.
• Other rare bleeding disorders whose mechanisms are not well understood (e.g., Bleeding Disorder of Unknown Cause, BDUC).

The Motherless Queen Scholarship Fund, established by Linda Hope, honors her mother’s legacy and supports college students who have lost their mothers. For over 30 years, the Community Foundation of Middle Tennessee has been committed to fostering positive change in Nashville's community. This scholarship specifically aids students attending Historically Black Colleges and Universities, especially those with ties to Florida A&M University, promoting educational opportunities and honoring the value of education.

The Penny Ann Powers Scholarship Fund, managed by the San Antonio Area Foundation, supports students pursuing an Associate Degree or vocational training. Eligible applicants include current high school seniors, college students, and adult learners with a high school diploma. This renewable scholarship emphasizes support for single mothers over 40 and requires a minimum GPA of 3.0. The fund aims to enhance educational opportunities and contribute to community development in the USA.

The Robert Sr. and Mary Churchwell Scholarship Fund, established by the Community Foundation of Middle Tennessee, honors the legacy of Robert Churchwell, Sr., a pioneering African American journalist, and Mary Elizabeth Buckingham Churchwell, a dedicated educator. This scholarship supports journalism students who demonstrate commitment and excellence in their field. Eligible candidates must maintain a 3.0 GPA and submit an essay on the role of journalism today. The fund aims to empower future journalists to reflect the diversity of the communities they serve.

About Pfizer Grants

Pfizer supports the global healthcare community’s independent initiatives (e.g., research, quality improvement or education) to improve patient outcomes in areas of unmet medical need that are aligned with Pfizer’s medical and/or scientific strategies.

Biochemical and Molecular Characterization of Marstacimab and TFPI Pathways 

This competitive grant encompasses research aimed at elucidating molecular and cellular mechanisms underlying marstacimab-TFPI interactions, including but not limited to differential expression of tissue factor and TFPI in various tissues, binding kinetics, and other biochemical properties. Projects should seek to advance foundational understanding of these interactions through innovative approaches in biochemistry, molecular biology, and related disciplines.

Project Types and Area of Interest

Projects that will be considered for Pfizer support will focus on basic science and fundamental biological understanding of Tissue Factor Pathway Inhibitor (TFPI), anti-TFPI Monoclonal Antibodies, and marstacimab. The areas of interest may include (but are not limited to):

• Basic biology of TFPI including interactions among key regulatory proteins in the intrinsic and/or extrinsic clotting cascades (e.g. Protein S being a co-factor for both Protein C and TFPI).
• Impact of differential TFPI expression within tissues and the role of various TFPI pools/isoforms in the regulation of coagulation.
• Pharmacology resulting from concomitant therapies added to anti-TFPI

The Fiscal Year 2026 Flood Mitigation Assistance program aims to enhance flood mitigation funding delivery, focusing on the needs of disaster survivors. This federal initiative, managed by FEMA, provides essential funds to states, territories, and local governments to mitigate flood risks and reduce repetitive damage to properties insured under the National Flood Insurance Program. The program supports various activities designed to lower the financial exposure of the NFIP while promoting community resilience against flooding.

Accreditation Sustainability Learning Community RFA

The Association of State and Territorial Health Officials (ASTHO), through the Public Health Infrastructure Grant (PHIG), is currently accepting applications for participation in a learning lab that will foster health department capacity to build a sustainable public health accreditation culture within their agencies. This opportunity is open to applicants from direct PHIG awardees at the state-, big city-, and county-level.

Mission & Vision

Rochester Area Community Foundation, in partnership with generous philanthropists and community partners, works to improve the quality of life for people who live and work in the eight-county region through its leadership and strategic grantmaking.

Our Mission:

We are cultivating a thriving Greater Rochester region — powered by philanthropy, grounded in community, and sustained across generations.

Our Vision:

We envision a Greater Rochester region transformed by enduring philanthropy, where every person, neighborhood, and future generation can thrive.

Joseph and Lorraine Finley Scholarship

Purpose of Scholarship

To provide financial support to high school seniors who are residents of the Wayne County town of Walworth and continuing their education at any accredited two-year, four-year, or technical school.

Number and Size of Awards

Four awards of $7,000 each; paid as $1,750 per year for up to four consecutive years of undergraduate study. Award paid in the Fall and divided equally between the Fall and Spring semesters.

Donor Information

This scholarship was established by a couple who believed in education and in helping their community.

The SPARK Research Match Expansion initiative by the Simons Foundation aims to enhance autism research participation among undersampled groups. By providing incentives for participants in online surveys and other research methods, this program seeks to address the demographic disparities in clinical research. This funding opportunity encourages innovative studies that prioritize inclusivity, ensuring that the research reflects the diverse population of the United States, thereby advancing scientific discovery in autism and related fields.

Susan G Komen Breast Cancer Foundation

The mission of Susan G. Komen® is to save lives by meeting the most critical needs in our communities and investing in breakthrough research to prevent and cure breast cancer.

Susan G. Komen Career Catalyst Research (CCR) Grants

Susan G. Komen Career Catalyst Research (CCR) Grants foster promising breast cancer researchers who are in the early stages of their faculty careers by providing support for up to three years of “protected time” for research career development under the guidance of a Mentor Committee. We seek to support those who will emerge as the next key leaders in the fight against breast cancer.

CCR Research Focus: Research projects must be hypothesis-driven, breast cancer-focused studies. They may be considered basic, translational, clinical and/or population science in nature and should align with Komen’s research priorities and mission to save lives from breast cancer. 

The Minnesota STEM and Youth Leadership Grants, offered by the H.B. Fuller Company Foundation, focus on empowering young individuals through STEM education and leadership development. These grants are intended for tax-exempt organizations that serve communities near H.B. Fuller facilities, aiming to address racial inequities in education and employment. The initiative underscores the company's commitment to community support and creating opportunities for youth to thrive in science, technology, engineering, and mathematics fields.

The DoW Bone Marrow Failure Idea Development Award supports innovative, high-impact research aimed at understanding and curing bone marrow failure diseases. This grant is available to both Established Investigators and Early-Career Investigators, with no preliminary data required for applications. Reviewers assess proposals based on specific criteria tailored to the investigator's career stage. The focus is on achieving interpretable results that contribute significantly to the field.

The Alcon Foundation focuses on enhancing global eye health through charitable monetary donations to 501(c)(3) organizations. Grants aim to support programs that improve access to quality eye care and education, fostering community development. Eligible applicants must demonstrate high-quality services, well-defined goals, and the ability to report outcomes. The foundation does not fund organizations that discriminate or are not 501(c)(3) compliant, ensuring that resources are directed towards impactful initiatives.

The DoW Bone Marrow Failure Investigator-Initiated Research Award supports innovative research aimed at advancing the understanding and treatment of bone marrow failure. This funding opportunity encourages applications for translational and clinical studies, requiring preliminary data to strengthen proposals. Unique features include the ability for a partnering Principal Investigator to contribute to the research, thereby fostering collaboration while maintaining a focus on significant advancements in patient care.

The Creative Native Call for Art invites Indigenous artists aged 5 to 24 to showcase their talents through diverse artistic expressions. Participants can submit works inspired by the theme of what is sacred to them and their community, with opportunities for national recognition and awards, including a grand prize of $1,000. This initiative aims to celebrate and support young artists in their creative journeys while honoring cultural significance and community values.

The National Institute on Aging (NIA) is inviting applications for the Alzheimer's Drug-Development Program (U01 Clinical Trial Optional). This initiative seeks to support pre-clinical and early-stage clinical development of innovative drug candidates aimed at preventing Alzheimer's disease or treating its symptoms. The program encourages collaboration among researchers and aims to enhance the therapeutic pipeline for AD through targeted approaches. This notice allows potential applicants time to prepare robust projects.

The FY26 Bone Marrow Failure Research Program's Resource Development Award aims to create a multiomic atlas from human bone marrow failure samples. This resource will be open-access, providing essential data for researchers and clinicians to enhance their understanding of bone marrow failure diseases. A comprehensive Data Resource Sharing Plan is required to ensure timely availability of the developed resource, fostering collaboration within the scientific community.

The Abrazo/Mitchard Birthmother Scholarship Fund, managed by the San Antonio Area Foundation, supports birthmothers who have placed their children for adoption through Abrazo Adoption Associates. This fund offers financial assistance for tuition and educational expenses for full-time students pursuing various degrees. Eligible applicants include adult learners and current college students. Although the scholarship is not renewable, recipients can apply for an additional year of funding, making education accessible to those in need.

The Ajay Castro Scholarship Fund, managed by the San Antonio Area Foundation, supports female undergraduate students pursuing a degree in communications. This scholarship is aimed at adult learners or current college students who have graduated high school or earned a GED. Although it is not renewable, recipients can reapply annually. Preference is given to those returning to college after a break, ensuring that the fund continues to empower women in education.

The FY26 Parkinson’s Research Program Investigator-Initiated Research Award supports innovative, multidisciplinary research projects aimed at advancing the understanding and treatment of Parkinson’s disease. The award encourages collaboration among multiple principal investigators, requiring preliminary data and allowing clinical trials to enhance research outcomes. This initiative is vital for fostering impactful discoveries within the four specified focus areas of the program, ultimately improving patient care and management.

The FY26 Parkinson’s Research Program (PRP) Early Investigator Research Award supports early-career researchers in Parkinson’s disease (PD) research. It offers two funding levels: Level 1 for fellows requiring a Mentor and Level 2 for independent investigators. The PI must show potential in PD research, with Level 1 emphasizing mentorship and Level 2 needing preliminary data. Research must align with one of the four FY26 PRP Focus Areas, excluding clinical trials.

The DOW Combat Readiness – Medical Research Program's FY26 Translational Research Award supports innovative research aimed at improving trauma care outcomes. This program emphasizes hypothesis-driven studies that can transition promising technologies into practical solutions for enhancing casualty survivability. Applicants must provide preliminary data and utilize validated animal models, with a focus on projects that meet a minimum technology readiness level of 4, ensuring a mature translational research effort.

The National Institute of Allergy and Infectious Diseases (NIAID) is advancing research on immune tolerance through its Collaborative Network. This program aims to clarify the mechanisms of immune tolerance and develop interventions for related diseases, including transplant rejection and autoimmune disorders. Key objectives include conducting clinical trials on tolerogenic strategies and refining immune assays. This initiative is supported by regulations under the Public Health Service Act, ensuring a structured approach to improving patient outcomes.