Best Large Grants for Nonprofit Organizations in Kentucky

The JSF Indigenous Peoples Grant Program is dedicated to fostering economic development in Indigenous communities through entrepreneurship and business education. With over 30 years of experience, the program supports Indigenous students with scholarships and capacity-building grants. It has produced more than 80 graduates from its MBA in American Indian Entrepreneurship, addressing barriers to education and employment, and enhancing opportunities for entrepreneurs. JSF's commitment to these initiatives is evident in its annual investment of approximately $500,000.

The JSF People with Disabilities Grant supports organizations that empower students with disabilities through education and employment opportunities. With a focus on scholarships and mentorship, the Foundation addresses barriers that hinder access to higher education. It has established partnerships with universities and schools, including Gallaudet University, to create impactful programs. Additionally, it funds initiatives that help transition individuals into the workforce, ensuring inclusivity in educational and professional settings.

The Blackstock Family Foundation Scholarship Fund, established by the Community Foundation of Central Georgia, offers scholarships to Georgia students pursuing degrees in healthcare, special education, or STEM fields. With a focus on supporting individuals with special needs, the fund provides at least one award annually, with renewal options for prior recipients. Eligible candidates must be Georgia residents, high school seniors or currently enrolled students, and maintain a minimum GPA of 2.7. Preference is given to students from Upson County.

Improving Indoor Environmental Quality Worldwide

Grants of up to $30,000 USD awarded annually to non-profit organizations researching indoor environmental quality and human wellbeing. No geographic limitations.

Halton Foundation provides grants for research focused on indoor air quality, thermal conditions, breathable particulates, and illnesses that may result from sub-standard indoor environmental quality.

Halton Foundation is a charitable organization with the aim of improving indoor environmental quality. Grants are awarded to non-profit organizations that research improvements in human wellbeing in indoor environments or develop solutions for enhanced indoor environmental quality.

Apply for a Halton Foundation Grant

Grants are awarded annually to non-profit organizations researching indoor environmental quality and human wellbeing.

The Frederick G. Byington and Christine Latta Byington Family Scholarship Fund, established by the Community Foundation of Central Georgia, supports students from Wilkinson County, GA, with limited financial resources. This scholarship aims to facilitate access to higher education, vocational training, and professional schooling. Annually, up to two recipients are chosen, with awards varying in amount. Previous recipients can renew the scholarship for up to four years, provided they meet eligibility criteria and complete necessary follow-ups.

The Frank and Audrey Senn, Sr. Memorial Scholarship Fund, established by the Community Foundation of Central Georgia, honors the legacy of Frank and Audrey Senn, lifelong supporters of education and community service. This scholarship aims to assist members of Trinity United Methodist Church in Newberry, SC, with their pursuit of higher education, offering at least $1,000 annually for up to four years. Eligible applicants must demonstrate academic commitment and community engagement.

The BJA FY 2026 Crisis Response Training Program aims to enhance public safety and law enforcement effectiveness by providing critical training for officers in responding to individuals experiencing behavioral health crises. This funding opportunity supports state, local, and tribal governments in developing programs to improve responses to those with mental health conditions, intellectual disabilities, and other challenges. By equipping officers with essential skills and strategies, the program seeks to ensure safer interventions and better outcomes in crisis situations.

The BJA FY 2026 Byrne State Crisis Intervention Formula Program aims to enhance state crisis intervention court proceedings and related initiatives. Funded by the U.S. Department of Justice, the program focuses on addressing public safety challenges such as violent crime, human trafficking, and the opioid crisis. Grants will support the development of mental health courts, drug courts, and extreme risk protection order programs, providing critical resources to improve community safety and support law enforcement efforts.

Society of Hospital Medicine (SHM)

The Society of Hospital Medicine (SHM) is dedicated to promoting high-value care and achieving optimal outcomes for acutely ill patients. As part of this mission, SHM seeks to address inequities in acute patient care and contribute to a greater dialogue on this important issue. As the home for hospitalists, SHM activates and engages our community to

• Advocate for our specialty, our members, and the diverse patients we serve.
• Promote high-value care and optimal outcomes for acutely ill patients.
• Meet the evolving educational needs of a dynamic specialty.
• Cultivate an inclusive community for hospitalists and support career growth and wellbeing.
• Advance the research and innovation of healthcare delivery, quality, safety, and experience across the care continuum.

Society of Hospital Medicine Travel Grant

The SHM Global and Rural Health Foundation brings our mission directly to patients in rural and underserved regions of the United States and abroad by offering small travel grants to hospital-based clinicians and practice administrators involved in this work. The Foundation also aims to amplify the stories of inequitable patient care and celebrate hospital medicine professionals enhancing outcomes.

The SHM Global and Rural Health Foundation awards travel grants of up to $2,000 per person for travel to qualifying relief programs. Travel grants will be awarded to support travel for work conducted through established nonprofits, such as Doctors Without Borders, or a program run by a nonprofit academic health center.

About the Emporia Community Foundation

Our Mission

To connect caring people with causes that build stronger communities within the Emporia area which includes Chase, Coffey, Greenwood, Lyon, Morris, Osage and Wabaunsee counties.

Pink Gravel Fund

The purpose of the Pink Gravel Fund is to provide funds to qualified individuals to cover expenses related to the treatment and recovery of breast cancer. 

The Human Trafficking Youth Prevention Education (HTYPE) Demonstration Program aims to empower local education agencies (LEAs) by funding initiatives that equip school staff to identify and respond to human trafficking signs. Collaborating with nonprofit partners, LEAs will provide students with essential knowledge on avoiding victimization and recognizing trafficking indicators. This program fosters a safer school environment by establishing reporting procedures and safety plans in consultation with local law enforcement, ultimately enhancing awareness and prevention of human trafficking in educational settings.

The Bausch Foundation, established by Bausch Health Companies Inc., supports global charitable initiatives focused on disease prevention, improving patient outcomes, and education related to its core businesses. The Foundation also aids disaster recovery efforts and assists underserved communities. Applications for funding are accepted continuously, with quarterly reviews, ensuring timely support for impactful projects. All submissions must be unsolicited, and decisions by the Advisory Committee are final, fostering a transparent giving process.

The Craig Newmark Philanthropies Grants, established in partnership with the Bob Woodruff Foundation, aim to support military and veteran communities through funding initiatives that enhance health and well-being. Since 2020, this program has positively impacted over 1.6 million veterans, service members, and their families. The grants focus on improving health determinants, increasing access to healthcare, and facilitating veterans' successful transitions to civilian life.

About

Our Story: Women Deserve More

At Women Founders Grant we are catalyzing a no BS movement for women to truly attain Financial Agency.

Women Founders Grant

If you have a dream, we want to support it. We are here to level the playing field and give you the guidance you need to turn that dream into a reality.

Our Grants

• $5,000 Grants on a rolling basis.
• No strings attached.
• This is our biggest differentiator. We know first hand how the folks who have the funds make you jump through unnecessary hoops. No hoops here.
• An Entrepreneur Business Yoda to mentor and coach you.
• GTM support to help you grow and get paying customers.
• On demand resources that guide you through your entrepreneur journey.

• Simply answer two questions on the application page.
• At the heart of our grants, there's no limit to your business dream. From pioneering scientists to artisan bakers, we encourage diverse passions and pursuits.
• So what truly matters is you—the woman or women driving the business forward. We value authenticity over corporate jargon; past winners have simply shared their stories - real passion and vision can’t be faked - so let your’s shine.
• We seek not only business acumen but also the fiery passion that fuels your entrepreneurial journey.

Interact For Health

Our organization started in 1997, when ChoiceCare sold its health maintenance organization to Humana for $221 million. The proceeds were invested and The Health Foundation of Greater Cincinnati was created, serving a 20-county region in Southwestern Ohio, Northern Kentucky and Southeastern Indiana. The foundation was charged with changing the way health care was delivered—especially for under-resourced communities.

Our mission is to ensure people in our region have a just opportunity to live their healthiest lives. Our Vision is focused on people in our region being healthy and thriving, regardless of who they are or where they live.

Interact For Health: Event Sponsorship

Interact for Health provides sponsorships as a way to support organizations within Greater Cincinnati with funding beyond our grantmaking work. Sponsorships are a competitive process, and funding is limited. We prioritize sponsoring events that serve our priority populations, align with our strategic plan, and benefit (and are located in) our 20-county service area.

In general, sponsorship opportunities are meant to benefit organizations that are not current grantees of Interact for Health. 

The CDC's initiative, 'Holistic and Evidence-Informed Wellness for STI Prevention', addresses the significant public health burden of STIs in the U.S. by promoting a comprehensive approach that emphasizes healthy choices and relationships. By supporting a coalition of sexual health experts, the program aims to enhance STI prevention through strategic resource allocation and the dissemination of high-quality, evidence-based materials, targeting priority groups most affected by STIs. This holistic strategy seeks to reduce STI morbidity and improve overall sexual health.

About Patient Advocate Foundation

Patient Advocate Foundation is the nation’s most comprehensive nonprofit dedicated to helping patients navigate, access, and afford the care they need—while improving the healthcare system for all.

Who we are and our impact

Patient Advocate Foundation provides financial assistance to help patients afford treatment and cost of living needs, personalized case management to navigate complex healthcare and social needs challenges, and a wide array of resources to empower people to take charge of their health. Since our founding in 1996—and joining forces with the PAN Foundation in 2026—we have helped 3.8 million patients navigate and access care, granted over $7 billion in financial assistance, served 350,000 people through personalized case management and elevated the patient’s voice to drive improvements in the healthcare system.

Cushing’s disease or syndrome

Help with healthcare costs for Cushing's disease or syndrome

This TotalAssist fund helps you pay for out-of-pocket healthcare costs, including medication copays, coinsurance, and deductibles, health insurance premiums, and other expenses.

About the disease

Cushing’s Disease or Syndrome, also known as Cushing’s Syndrome, hypercortisolism and hyperadrenalism, is a condition where the pituitary gland releases high levels of the hormone cortisol. It is a rare disease that affects the endocrine system.

About Patient Advocate Foundation

Patient Advocate Foundation is the nation’s most comprehensive nonprofit dedicated to helping patients navigate, access, and afford the care they need—while improving the healthcare system for all.

Who we are and our impact

Patient Advocate Foundation provides financial assistance to help patients afford treatment and cost of living needs, personalized case management to navigate complex healthcare and social needs challenges, and a wide array of resources to empower people to take charge of their health. Since our founding in 1996—and joining forces with the PAN Foundation in 2026—we have helped 3.8 million patients navigate and access care, granted over $7 billion in financial assistance, served 350,000 people through personalized case management and elevated the patient’s voice to drive improvements in the healthcare system.

Amyloidosis

Help with healthcare costs for amyloidosis

This TotalAssist fund helps you pay for out-of-pocket healthcare costs, including medication copays, coinsurance, and deductibles, health insurance premiums, and other expenses.

About the disease

Amyloidosis is characterized by a build-up in amyloid protein in specific organs or throughout the body. It is a rare disease that affects multiple systems. Subtypes include hereditary amyloidosis, light chain amyloidosis (AL amyloidosis), and amyloid A (AA) amyloidosis (secondary amyloidosis).

The BJA FY 2026 Harold Rogers Prescription Drug Monitoring Program aims to enhance the capabilities of agencies in collecting and analyzing prescription data for controlled substances. By establishing a centralized database, this initiative will aid in the prevention of drug diversion and abuse, particularly of opioids. The program emphasizes the integration of data with health information exchanges and electronic health records, fostering local decision-making while addressing the needs of tribal and rural areas to combat substance abuse effectively.

Siemens Healthineers offers educational grants aimed at enhancing professional education in the healthcare sector. These grants support various clinical, technical, and scientific education programs, including medical imaging and laboratory diagnostics. The funding is intended for events that promote best practices and clinical demonstrations, providing healthcare professionals with the necessary tools to improve patient care outcomes. Applications must be submitted at least 45 days prior to the event, ensuring adequate time for review and approval.

The BJA FY 2026 Investigating and Prosecuting Sexual Assaults in Confinement Facilities Program aims to enhance state, local, and tribal capacities to investigate and prosecute sexual assault incidents within confinement facilities. This funding opportunity is designed for law enforcement and prosecutorial agencies to effectively address and reduce sexual assault occurrences while improving prosecution success rates. Applications are due by September 30, 2026, at 8:59 PM ET.

The James J. and Joan A. Gardner Family Foundation focuses on enriching lives and making a positive impact in local communities. They prioritize funding for tax-exempt organizations that enhance education, health care, and support the under-served. The Foundation seeks to partner with those who demonstrate accountability and effective resource management, aligning with their mission for community enrichment and leadership development.

Spencer Educational Foundation Inc

The Spencer Educational Foundation was founded by the Rims Atlanta Chapter in 1979. To this day, Spencer remains the premier organization funding the education of tomorrow's risk management and insurance leaders.

The Spencer Educational Foundation: awards merit-based scholarships and grants to university students pursuing careers in risk management, insurance, and/or actuarial science; provides grants that create experiential learning opportunities both on and off campus; funds the development of risk management and insurance curricula in colleges and universities; supports Risk Managers by creating internship opportunities within the risk management function of their companies; and operates across the United States and Canada. 

Spencer Educational Foundation: Spencer Success Stipend

The Spencer Success Stipend is a student support initiative created to help reduce financial barriers associated with internship opportunities in the risk management and insurance industry. The program provides funding to eligible students to assist with internship-related expenses that may otherwise make it difficult to participate in valuable experiential learning opportunities.

Through the Spencer Success Stipend, students may receive support for expenses such as housing, transportation, professional attire, technology, relocation costs, work-related meals, licensing or background check fees, and other direct internship participation costs. The goal of the program is to ensure students can fully engage in career-building experiences that strengthen their professional development, industry exposure, and long-term success.

Thanks to the generous support of Allied World and Munich Re, Spencer is proud to expand access to these opportunities and continue investing in the next generation of industry talent. Applications are reviewed on a rolling basis.

Spencer Educational Foundation Inc

The Spencer Educational Foundation was founded by the Rims Atlanta Chapter in 1979. To this day, Spencer remains the premier organization funding the education of tomorrow's risk management and insurance leaders.

The Spencer Educational Foundation: awards merit-based scholarships and grants to university students pursuing careers in risk management, insurance, and/or actuarial science; provides grants that create experiential learning opportunities both on and off campus; funds the development of risk management and insurance curricula in colleges and universities; supports Risk Managers by creating internship opportunities within the risk management function of their companies; and operates across the United States and Canada. 

Spencer Educational Foundation: Course Development Grants

Since 2014, Spencer has invested over $1.6 million in developing risk management and insurance (RMI) courses at close to 70 colleges and universities, exposing approximately 19,000 students to the RMI industry.

Our Course Development Grant program supports Introductory Risk Management and Insurance Course Development - for universities that have not previously offered any such instruction - as well as proposals for additional Course Curriculum Development and Program Development - for universities looking to develop a RMI program and/or expand existing RMI course offerings, with an emphasis on new and emerging areas in the industry.

The Harbor Freight Tools for Schools Grant Program, initiated by Eric Smidt through The Smidt Foundation, supports high school students in skilled trades education. This initiative facilitates pathways to graduation and fosters opportunities for meaningful employment. Each year, it awards $1.5 million in cash prizes to 25 exceptional U.S. public high school skilled trades teachers, enhancing support and investment in trades education. This program is a vital resource for schools aiming to improve their vocational training.

The BJA FY 2026 Local Law Enforcement Crime Gun Intelligence Center Integration Initiative aims to support law enforcement agencies in establishing and expanding Crime Gun Intelligence Centers (CGICs). This initiative encourages interagency collaboration for the effective management and analysis of crime gun evidence, enhancing the ability to swiftly identify crime guns and their sources. In partnership with the ATF, this program seeks to reduce firearm-related crime and improve prosecution outcomes.

The Preventing Violence Affecting Young Lives (PREVAYL 2.0) initiative aims to provide multiyear funding for state and local health departments to implement violence prevention strategies for adolescents and young adults. Key focuses include enhancing data-driven decision-making, building capacity for evidence-based strategies, integrating youth mental health support, fostering multisector collaborations, and prioritizing the prevention of various forms of violence, ensuring comprehensive support for youth development.