Best Large Grants for Nonprofit Organizations in Kentucky

The B-Fund Grant by the Brem Foundation aims to enhance early detection of breast cancer by funding crucial screening and diagnostic tests for women in need. This initiative supports entities in the DC metro area, providing financial assistance for services like mammograms and ultrasounds, while ensuring equitable access regardless of socio-economic status. However, it excludes costs related to post-diagnosis care, employee salaries, and administrative expenses, promoting targeted and effective use of funds in the fight against breast cancer.

The Abortion Bridge Collaborative Funds, initiated by the Women Donors Network, aim to enhance abortion access across the U.S. in response to the 2022 Dobbs decision. The fund prioritizes support for 501c3 organizations committed to reproductive justice, focusing on immediate community needs and sustainable solutions. Emphasizing grassroots leadership and innovative approaches, the fund seeks to build a robust infrastructure for reproductive care, ensuring equitable access for all individuals in need.

The Genentech Foundation supports innovative projects that address systemic inequities in healthcare. They fund tax-exempt organizations, including public charities and governmental entities, located in the U.S. Grant requests must be submitted at least 60 days before the project start date. Notably, projects must align with Genentech's commitment to advancing health equity and diversity in the medical workforce. Applications for funding will be accepted starting January 2, 2026, after a temporary closure.

The AHRF Birtman Grant provides up to $75,000 for one year of research focused on hearing and balance disorders related to the inner ear. This grant encourages both basic and clinical studies, covering direct costs such as staff salaries and research equipment. Applicants must hold relevant advanced degrees and be affiliated with a U.S. university or hospital. An alternative budget option of $50,000 is available, enhancing eligibility for Regular grants if not awarded the Birtman Grant.

The AGA-R. Robert & Sally Funderburg Research Award in Gastric Cancer aims to support established investigators in gastric cancer research. This award focuses on enhancing the understanding of gastric cancer pathobiology and developing strategies for prevention, treatment, and cure. Eligibility includes holding an MD or PhD, with specific experience requirements. The American Gastroenterological Association encourages applications, particularly from underrepresented groups in biomedical research, to foster diversity in the field.

The Changemakers in Family Planning Grant Program aims to address institutionalized racism in the field of family planning by providing essential support to scholars of color. Recognizing that diversity and equity are crucial for advancing research in abortion and contraception, this initiative seeks to foster an inclusive community that empowers underrepresented voices in science. The Society of Family Planning is dedicated to creating a just environment where all scholars can contribute to meaningful advancements in family planning research.

The Tri-M Foundation's Performing Arts Grant Program aims to support innovative and high-quality performing arts projects by regional non-profit organizations. The program prioritizes projects that align with the organization's mission, engage audiences, and provoke important discussions. Grants range from $3,000 to $10,000, intended for diverse artistic expressions, including theatre and dance. Applications are encouraged from eligible organizations that demonstrate detailed project planning, inclusivity, and a commitment to addressing sensitive topics.

The Weiss Writing Prize, established by the American College Health Foundation in 2010, aims to enhance mental health care quality for college students. It honors the lead author of a significant publication addressing student retention programs for those with mental health challenges. By fostering innovative and effective solutions, this prize encourages the dissemination of impactful research among American College Health Association members, ultimately contributing to the well-being and success of students across campuses.

The Stephan D. Weiss Student Mental Health Award, established by the American College Health Foundation, aims to enhance mental health support for college students. Offering $5,000 annually, it encourages innovative initiatives that can improve mental health service delivery and student retention. Eligible applicants are members of the American College Health Association, focusing on identifying mental health needs and developing effective campus-wide strategies. This award addresses growing concerns regarding mental health issues in higher education, fostering a supportive learning environment.

The Emily Hall Tremaine Exhibition Research Grant supports innovative projects that explore contemporary art in new frameworks. With a focus on education in the United States, the foundation emphasizes the importance of research that challenges conventional thought. Grants of $10,000 are awarded to curators collaborating with established non-profits, promoting impactful exhibitions. The foundation aims to foster family unity and respect while addressing enduring societal issues through art, environment, and learning differences.

The Emily Hall Tremaine Exhibition Award, established in 1998, supports innovative, thematic exhibitions that present contemporary art within unconventional frameworks. It fosters creativity by offering funding up to $200,000 for curators partnering with non-profit spaces. The award encourages exploration of critical ideas, emphasizing intellectual quality and public impact. Eligible applicants include established curators and institutions, aiming to promote artistic expression while enhancing community engagement and discourse through diverse projects.

The AOTF Implementation Research Grant supports innovative research aimed at integrating evidence-based practices into occupational therapy. This grant encourages projects that directly involve stakeholders, particularly from underrepresented populations, to address health inequities. With funding options of up to $100,000 for two years or $50,000 for one year, the AOTF seeks to enhance the effectiveness of care through practical implementation strategies in diverse clinical settings.

The Bonita Kraft Occupational Therapy Doctoral Student Scholarship, valued at $5,000, supports doctoral candidates in occupational therapy focusing on mental health research. This scholarship honors Bonita Kraft, a dedicated advocate for integrating occupational therapy into mental health services. Eligible applicants must be enrolled in a doctoral program, have IRB approval, and conduct research addressing chronic mental health conditions in adults. The scholarship aims to enhance the visibility of occupational therapy within mental health treatment.

The AISES Sports and Technology Scholarship aims to empower Indigenous students pursuing degrees in STEM fields. Sponsored by the American Indian Science and Engineering Society, this scholarship supports American Indian, Alaska Native, Native Hawaiian, Pacific Islander, and First Nations students, ensuring they have the financial resources needed to excel. Eligible applicants must be full-time students in accredited programs and demonstrate tribal affiliation, contributing to a diverse future in technology and science.

The Parkinson Association of the Rockies Eric Wright Memorial Fund honors Eric Wright's legacy by providing scholarships to high school seniors and college students affected by Parkinson Disease. Recipients, eligible for up to $20,000 over four years, are selected based on merit and financial need. This fund aims to inspire the next generation while supporting students who have experienced loss or hardship due to this condition, promoting education and resilience within the community.

The Robert Mapplethorpe Foundation, established in 1988, supports photography programs at museums and public institutions. It promotes photography's recognition alongside other art forms and contributes to HIV/AIDS medical research. Notably, it has funded major galleries and initiatives, donating significant collections to renowned museums. The Foundation aids curators in developing photography exhibitions and provides financial support for acquisitions, exhibitions, and publications, ensuring Mapplethorpe's artistic legacy endures.

The Never Lose Hoop Fund, established by JC and Joni Hulls, provides grants to support families affected by cancer. The fund aims to enhance the quality of life for children and their families through shared experiences, such as family camps and outdoor activities. Grants are available for those currently battling cancer or who have lost an immediate family member to cancer within the last two years. This initiative helps families create lasting memories and find joy during difficult times.

The Trails Capacity Program, previously known as the Trail Fund Grant, aims to enhance community capacity for trail maintenance, research, and stewardship training across the nation. The program focuses on supporting non-Forest Service Federal lands, as well as state and local areas, fostering inclusivity and improved user behavior. By collaborating with diverse trail partners, it seeks to ensure effective stewardship and sustainable trail management, ultimately promoting public access and enjoyment of America's natural landscapes.

The ChemClub Student Scholarship, offered by the American Chemical Society and the American Association of Chemistry Teachers, supports high school seniors who are active members of a Chartered ChemClub. Eligible students must demonstrate academic excellence and express their commitment to STEM fields. This scholarship provides financial assistance directly to the recipient's chosen college, fostering future leaders in chemistry and related disciplines.

Casey's Cash for Classrooms Grants support K-12 public and nonprofit private schools through funding for physical improvements, material needs, teacher support, and community engagement. In 2025, $900,000 was awarded across 80 grants, allowing schools to enhance their learning environments. With a commitment to community engagement, Casey's has donated $15 million since 2019, emphasizing their dedication to making life better for communities and guests. Grants range from $3,000 to $50,000, with funds required to be used within 12 months.

Devinci's Community Grant Program aims to support North American cycling organizations with financial assistance for development projects. Eligible applicants include cycling clubs, non-profits, and individuals leading community initiatives. Projects must occur in Canada or the U.S. within the year, with a maximum grant of $5,000 CAD. The program collaborates with key industry partners to foster growth in the cycling community, making a lasting impact through local initiatives.

The Youth Incentive Award, established by the Coleopterists Society, encourages students in grades 7-12 to explore the fascinating world of beetles. Annually, up to $1200 is awarded, with two grants of $400 and $800 for junior and senior categories, respectively. Recipients also receive a subscription to The Coleopterists Bulletin. The program aims to promote beetle studies, develop essential life skills, and provide financial support for educational projects, fostering a passion for entomology among youth.

The Ross Merrill Award for Outstanding Commitment to the Preservation and Care of Collections recognizes North American institutions demonstrating exceptional dedication to conservation. This award highlights organizations that engage in significant outreach, involve conservation professionals, and show a commitment to community education regarding the importance of preserving cultural heritage. While no monetary prize accompanies the award, it serves as a prestigious acknowledgment of exemplary conservation efforts. Nominations are encouraged from both inside and outside organizations.

The AAS Northeast Asia Council (NEAC) Distinguished Speakers Bureau Grant invites applications from U.S. and Canadian colleges to host distinguished scholars for public lectures on Japan and Korea. This program, initiated in 2011, aims to foster engagement with early career scholars and enhance East Asian studies. Grants cover honoraria of $500 and additional funding for in-person events, promoting accessibility and academic collaboration. Institutions are encouraged to apply every three years, ensuring support for smaller programs in Asian studies.

The CERF: Artist Get Ready Grant offers up to $1,000 to craft artists for safeguarding their studios and preparing for emergencies. Priority is given to underrepresented artists, including BIPOC and folk/traditional artists. Eligible activities encompass studio safety upgrades and disaster readiness. Applicants must be 18 years or older, residing in the U.S. for two years, and not have received this grant in the previous year. Funds must be used within six months, with outcomes documented for CERF+.

The Hilda M. Hill Memorial Scholarship is offered by the Four County Community Foundation to support high school seniors and recent graduates from Capac, Almont, and Imlay City. Eligible students planning to pursue vocational or technical programs may apply, with financial need considered. Recipients will be recognized at the Foundation Scholarship Celebration in May, as well as during high school awards ceremonies. Students can receive up to two awards, promoting continued educational advancement in skilled trades.

The Biocodex Microbiota Foundation invites early career researchers in the microbiome field from U.S. institutions to apply for the 2024 grant. This initiative focuses on groundbreaking research into gut microbiota's role in human health and disease, particularly in areas like circadian rhythms and metabolic disorders. The grant supports operational costs, allowing for innovative projects aimed at fostering independent research careers in microbiota studies.