Upcoming Webinar
How Funders Feel About AI, and What Keeps Them Saying Yes.
Wed, Oct 14 @ 2PM ET

Skip to main content
Main content

Best Large Grants for Nonprofit Organizations in Kentucky

Find the perfect Large Grants for Nonprofit Organizations in Kentucky on Instrumentl. 9,000+ Large Grants for Nonprofit Organizations in Kentucky in the United States.

9,000+

Available grants

$2.61B

Total funding

$5K

Median grant

9,000+ grants
$2.61B total
$5K median

Skip the search. Get matched with grants that fit your non-profit.

Skip the search.

Get matched with grants that actually fit.

Smart recommendations based on your profile — in minutes.

Find me grants

Filters

9,423 Results based on applied filters

HEAL Initiative-Early-Stage Discovery of New Pain Targets Within the Understudied Druggable Proteome (R03 Clinical Trial Not Allowed) (357655)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Up to US $100,000
The HEAL Initiative aims to identify new druggable targets for pain within the understudied proteome. This funding opportunity invites applications for pilot projects that generate preliminary data and tools for exploring these targets. The initiative seeks to enhance research on understudied proteins related to pain management, providing essential funding for biochemical and biological work. This NOFO is part of the NIH's broader effort to develop novel medications that address various aspects of opioid addiction and its consequences.
Chronic / Acute Pain Anesthesia and Pain Medicine Drug Use Disorder +1 more

Hazen and Sawyer Scholarship

American Water Works Association (AWWA)
Association/Society
United States
US $10,000
The Hazen and Sawyer Scholarship, valued at $10,000, is awarded annually to a graduate-level candidate dedicated to addressing critical challenges in drinking water, water reuse, and water resources. Sponsored by the American Water Works Association (AWWA), this scholarship supports students who are permanent residents of the U.S., Mexico, or Canada. Eligible funds cover tuition, books, and related educational expenses, enhancing the recipient's ability to contribute to the water industry.
Environmental Contamination & Pollution Water Resource Management Environmental Policy

Old National Bank Foundation Sponsorships

Old National Bank
Corporate
Allen County, Indiana, Berrien County, Michigan +58 more
Unspecified amount
The Old National Bank Foundation provides sponsorships to enhance community initiatives in Indiana, Illinois, Kentucky, Michigan, Minnesota, and Wisconsin. Their mission focuses on social responsibility, supporting underrepresented groups, and aligning with the Community Reinvestment Act. Sponsorships cover events such as fundraisers and sporting events, emphasizing active engagement and measurable impact. The Foundation aims to improve quality of life through strategic partnerships and meaningful contributions.
Financial Literacy Economic Services & Development Workforce Preparation & Job Readiness +2 more

Dr. Bruce D. J. Batt Fellowship in Waterfowl Conservation

Ducks Unlimited
Private
North America
Up to C $5,000
The Dr. Bruce D. J. Batt Fellowship in Waterfowl Conservation honors the legacy of Dr. Bruce Batt, a leading figure in waterfowl research. This fellowship offers up to $5,000 annually to graduate students at North American universities conducting vital research on waterfowl and wetlands. Renewable for up to two additional years for PhD students, the fellowship promotes the integration of sound science in conservation efforts, supporting the next generation of waterfowl professionals.
Ecology Ornithology Limnology +1 more

Elizabeth Furber Scholarship

Native Forward Scholars Fund
Association/Society
United States
US $100 - US $30,000
The Elizabeth Furber Scholarship honors the legacy of Elizabeth Furber by providing financial assistance to American Indian and Alaska Native female graduate students. This scholarship supports students pursuing full-time degrees in various fields, including fine arts, music, and creative writing. As a need-based award, it requires applicants to demonstrate Tribal affiliation through a Tribal Eligibility Certificate. This opportunity empowers eligible students to achieve their academic goals.
Academic Scholarship Programs Writing & Literature Performing Arts +6 more

Confluence Program Grants

Conservation Alliance
Private
Canada, United States
US $140,000
The Confluence Grant Program, initiated by the Conservation Alliance in 2021, aims to strengthen partnerships with historically racially excluded groups. It awards four grants of $100,000 over two years to support projects that protect or restore natural places. The program emphasizes building meaningful relationships and sharing resources, ensuring that funded projects center on solutions led by impacted communities. By fostering collaboration and addressing funding gaps, the program enhances the conservation landscape for diverse voices.
Environmental Justice & Advocacy Environmental Conservation Asian / Pacific Island Culture & Heritage +3 more

Bay Area Lyme Foundation Grant

Bay Area Lyme Foundation
Private
United States
Unspecified amount
The Bay Area Lyme Foundation Grant supports innovative research aimed at improving diagnostics and treatments for Lyme disease. With a revised granting schedule, proposals can be submitted year-round, with reviews conducted three times annually. The foundation welcomes applications from universities, hospitals, and independent entities across the U.S., emphasizing the importance of addressing challenges in diagnosing and treating Lyme disease, especially for difficult cases.
Acarology Lyme Disease

Crossing the Divide – Best Practices for Addressing Local and Privately-Owned Lateral Sewer Issues RFP

Water Research Foundation
Private
Countries
Up to US $250,000

About Us

advancing the science of water ®

Who We Are

The Water Research Foundation (WRF) is the leading research organization advancing the science of all water to meet the evolving needs of its subscribers and the water sector. WRF is a 501(c)(3) nonprofit, educational organization that funds, manages, and publishes research on the technology, operation, and management of drinking water, wastewater, reuse, and stormwater systems—all in pursuit of ensuring water quality and improving water services to the public.

5419 - Crossing the Divide – Best Practices for Addressing Local and Privately-Owned Lateral Sewer Issues

Grant Information

To provide water resource recovery facilities (WRRFs) and collection system operators with an interactive manual of practice for implementing inflow and infiltration (I&I) and obstruction management programs with a focus on municipal and privately owned lateral sewers in complex legal, regulatory, and multi-jurisdictional environments.

Water Resource Management Sanitation & Clean Drinking Water Environmental Contamination & Pollution

Cheerful Giver Scholarship

Community Foundation of the Central Blue Ridge
Private
United States
Unspecified amount
The Cheerful Giver Scholarship, provided by the Community Foundation of the Central Blue Ridge, offers over $300,000 in financial support to students in the Greater Augusta County area pursuing health care-related education. This need-based scholarship is open to high school seniors, current college students, and adult learners, with a preference for those entering the nursing profession. The foundation aims to enhance community well-being through educational opportunities.
Education - Higher Education Educational Access & Equity Nursing +3 more

Board of Associates Centennial Pollinator Fellowship

Garden Club of America
Association/Society
United States
Approximately US $4,000
The Garden Club of America Board of Associates Centennial Pollinator Fellowship offers funding for research on pollinator decline, specifically targeting bees, bats, butterflies, and moths. This fellowship, established in 2013, supports graduate students in U.S. institutions with annual funding typically around $4,000. It aims to enhance knowledge in pollinator science while fostering a new generation of scientists dedicated to conservation. Recipients may reapply for additional funding in subsequent years.
Entomology Mammalogy Pollinator Conservation

AmeriCorps Seniors RSVP Opportunity

Volunteer Mississippi
State/Local Government
United States
Up to US $75,000

AmeriCorps Seniors RSVP Opportunity

About RSVP

Established in 1971 and now one of the largest senior volunteer programs in the nation, AmeriCorps Seniors RSVP engages people ages 55 and older in a diverse range of volunteer activities. AmeriCorps Seniors RSVP volunteers tutor children, help prepare simple taxes, assist victims of natural disasters, provide nutrition/food support, facilitate opioid and substance abuse education workshops, and serve in their communities in many other ways. AmeriCorps Seniors RSVP volunteers choose how, where, and how often they want to serve, with commitments ranging from a few hours to a maximum of 40 hours per week. While serving, AmeriCorps Seniors RSVP volunteers improve their own lives by staying active and civically engaged. 

Funding Priorities

AmeriCorps Seniors RSVP programming is designed to meet community needs. Applicants may propose activities intended to address community needs by thoroughly explaining the unmet need and activities to be completed by volunteers to address that need. In addition, AmeriCorps is interested in programming that addresses agency priorities. AmeriCorps Seniors RSVP priorities for this funding opportunity are:

  • Supporting Older Adults and Caregivers: Provide respite, support groups, system navigation, care coordination, and resources for older adults, including custodial grandparents, and caregivers.
  • Helping Older Adults Re-enter the Workforce: Offer job readiness, mentoring, training, and remove barriers to employment for older adults (volunteers provide services, not seek jobs).
  • Building Strong Families: Support parents in helping children succeed, mentor parents, connect families to resources, and strengthen community partnerships.
  • Preventing and Mitigating Fraud and Scams: Use digital navigators and other strategies to protect older adults from financial fraud and exploitation, including emerging AI-driven scams.
  • Reducing Homelessness: Develop or renovate affordable housing, assist people experiencing homelessness in finding and maintaining permanent housing, and address housing needs for vulnerable populations.
  • Supporting Behavioral Health Initiatives: Improve mental health, reduce isolation, prevent substance use, provide harm reduction tools (Naloxone, fentanyl test strips), peer support, and recovery services.

Award Funding Requirements

Applicants must construct the budget in the following manner. The federal share of the budget must not exceed $75,000 plus up to $350 for every unduplicated volunteer, whether or not they serve in an outcome-based work plan. 

Senior Services Poverty Alleviation & Services Workforce Preparation & Job Readiness +2 more

Rapid Impact Research Award

American Heart Association
Association/Society
United States
Up to US $100,000

Over our more than 100-year history, we've been fighting heart disease and stroke, striving to save and improve lives.

Our Mission

To be a relentless force for a world of longer, healthier lives.

Rapid Impact Research Award

Purpose

The American Heart Association continuously seeks innovative ideas to address the most pressing issues impacting cardiovascular and brain health. To that end, the Association is pleased to announce the Rapid Impact Research Award program, which will support early and mid-career investigators proposing innovative research that aligns with the Association’s mission. Novel basic, clinical and/or population health proposals are invited in the following three priority areas of research.

  • Sudden cardiac arrest/resuscitation science
  • Cardiovascular Kidney Metabolic Syndrome
  • Stroke and/or vascular dementia

Applicants will be asked to indicate alignment of their proposal with one or more of the topic areas listed above. 

Cardiovascular Diseases & Systems Neurological Diseases & Disorders Stroke +1 more

DARRP Restoration Implementation Grants (2026)

National Oceanic and Atmospheric Administration (NOAA)
Federal Government
American Samoa, Guam +4 more
US $2,500,000 - US $100,000,000
The DARRP Restoration Implementation Grants aim to enhance marine and coastal habitat restoration through collaboration between NOAA and non-federal partners. These grants address oil spills and hazardous substance releases by supporting restoration activities authorized under various environmental laws. Eligible applicants will implement projects that promote sustainable fisheries, recover endangered species, and boost local economies. Through careful planning and evaluation, recipients will contribute to effective restoration strategies that align with NOAA's mission and the needs of coastal communities.
Habitat & Ecosystem Restoration Marine / Ocean Conservation Environmental Contamination & Pollution +2 more

Grants for Community Recycling Programs

The Recycling Partnership
Private
United States
Unspecified amount
The Recycling Partnership offers grants for community recycling programs, providing nearly $50 million to support 370 communities since 2014. Their mission is to create a robust and accessible recycling system that benefits people and the environment. Eligible applicants include publicly, privately, and non-profit owned MRFs in the U.S. This initiative aims to enhance curbside, drop-off, and multifamily recycling, ensuring that everyone can participate in sustainable practices.
Waste Management Recycling

Grants for Processors/Materials Recovery Facilities (MRF)

The Recycling Partnership
Private
United States
Unspecified amount

About Us

The Recycling Partnership is a team of experts, practitioners, and thought leaders who are deeply invested in protecting our natural resources, creating more sustainable communities, and delivering on our mission of building a better recycling system. We work alongside communities, companies, and policymakers to enact meaningful change across the entire recycling industry.

We firmly believe that if you want to recycle, you should be able to recycle. A robust and accessible recycling system is how we achieve this goal. A better system will deliver the true economic and environmental benefits that our people, our communities, and our entire recycling industry deserve.

This is our mission. This is our purpose. This is who we are. 

Grants for Processors/Materials Recovery Facilities (MRF)

Designed to help equipment manufacturers and MRFs boost throughput and increase capacity. 

Waste Management Recycling

W. Wesley Eckenfelder Graduate Research Award

Association of Environmental Engineering and Science Professors Foundation (AEESP Foundation)
Association/Society
United States
US $1,500
The W. Wesley Eckenfelder Graduate Research Award, administered by the AEESP Foundation, recognizes outstanding graduate students in environmental engineering and science whose research enhances wastewater management knowledge. This prestigious annual award offers a $1,500 honorarium and a plaque for winners, along with a $500 travel stipend for attending the AAEES awards ceremony. Eligible candidates include both Master’s and Ph.D. students who demonstrate exemplary academic performance and innovative research contributions.
Water Resource Management Academic Success & Enrichment Environmental Stewardship +1 more

GLS Campus Suicide Prevention (363809)

Substance Abuse and Mental Health Services Adminis
Federal Government
United States
Unspecified amount
The GLS Campus Suicide Prevention program aims to enhance behavioral health services for college students, addressing critical issues such as suicide, depression, and substance use disorders. By fostering a culture of help-seeking and reducing stigma, this initiative ensures that at-risk students receive timely intervention and support. The program represents a vital investment in the mental well-being of students, promoting a healthier campus environment through evidence-based strategies and comprehensive public health approaches.
Mental Health & Psychiatric Diseases Addiction & Substance Use Disorders Health Care Access & Delivery +1 more

Student & Resident Research Award

Rheumatology Research Foundation
Private
United States
US $2,000
The Student & Resident Research Award, part of the Choose Rheumatology campaign, recognizes outstanding students and residents for significant contributions in rheumatology. Eligible applicants must be authors of abstracts submitted to ACR Convergence 2025 and can receive up to $2,000 in funding for travel and registration. This award promotes engagement in rheumatology through innovative learning experiences at ACR Convergence, enhancing the understanding and care for patients with rheumatic diseases.
Musculoskeletal Diseases Immune System Diseases Arthritis +1 more

Rheumatology Scholarship – Workforce Expansion

Rheumatology Research Foundation
Private
United States
US $2,000
The Rheumatology Scholarship – Workforce Expansion aims to recruit future rheumatology professionals by supporting students and residents from underserved areas to attend ACR Convergence 2025. Awardees receive $2,000 for travel, registration, and a one-year ACR/ARP Membership. This initiative fosters networking opportunities and educational experiences crucial for enhancing patient care in rheumatology. It is part of a broader campaign to address the growing shortage of rheumatologists and improve patient access to care.
Musculoskeletal Diseases Immune System Diseases Arthritis +1 more

Rheumatology Scholarship – Undergraduate Students and Post-Baccalaureate Training

Rheumatology Research Foundation
Private
United States
US $2,000
The Rheumatology Scholarship supports undergraduate and post-baccalaureate students in attending ACR Convergence 2025, a premier event for rheumatology. Awardees gain exposure to innovative research and networking opportunities, enhancing their understanding of rheumatic diseases. The scholarship includes $2,000 for travel expenses and complimentary registration, encouraging future professionals to explore careers in this essential field. This initiative aims to strengthen the rheumatology workforce, ensuring better care for patients with musculoskeletal diseases.
Musculoskeletal Diseases Immune System Diseases Arthritis +1 more

Medical and Graduate Student Preceptorship

Rheumatology Research Foundation
Private
United States
US $4,000
The Medical and Graduate Student Preceptorship provides a unique opportunity for students to engage in rheumatology through either clinical or research experiences lasting 4 to 8 weeks. Participants will observe practices in a shadowing role, gaining invaluable insights without direct patient management. The program supports students with financial awards of $2,000 or $4,000, depending on the duration of their preceptorship, and includes additional funds for travel expenses to attend professional conferences.
Musculoskeletal Diseases Immune System Diseases Arthritis +1 more

Improving Health Decision Making With Comparative Clinical Effectiveness Research: Retrospective Observational Studies Leveraging Existing Data Sources PCORI Funding- Cycle 1 2026

Patient-Centered Outcomes Research Institute
Association/Society
United States
Up to US $2,000,000
This funding opportunity from the Patient-Centered Outcomes Research Institute aims to enhance health decision-making through comparative clinical effectiveness research, focusing on critical areas such as cancer, maternal health, and mental health. The initiative encourages robust observational studies that utilize existing data to derive patient-centered insights. Applications must address specific themes approved by PCORI and demonstrate potential benefits to the U.S. healthcare system, thus ensuring relevance and stakeholder engagement in research efforts.
Cancer / Oncology Maternal And Perinatal Health Endocrine & Metabolic Diseases +2 more

HIV Prevention and Alcohol (R61/R33 Clinical Trials Optional)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The HIV Prevention and Alcohol R61/R33 funding opportunity aims to advance innovative HIV prevention strategies through a phased research approach. The R61 phase focuses on developing and pilot testing interventions, addressing key implementation questions for diverse populations. Following successful milestones, the R33 phase expands testing of these interventions and explores their effectiveness and sustainability, particularly in relation to alcohol use and related health issues.
Infectious & Parasitic Diseases HIV / AIDS Preventative Healthcare

15 and the Mahomies Foundation Grants

15 And The Mahomies Foundation
Private
United States
Up to US $15,000
The 15 and the Mahomies Foundation Grants aim to enhance the lives of children by supporting health, wellness, and community initiatives. This private foundation seeks to fund 501(c)(3) non-profit organizations, focusing on charitable causes. Grant requests are reviewed quarterly, and applicants must meet eligibility criteria. However, the foundation does not accept applications from individuals or for non-charitable items such as autographs or game tickets.
Children’s Health & Pediatrics Children’s Mental Health Children With Disabilities +4 more

Alzheimer's Disease Programs Initiative (ADPI) - Developing Dementia-Capable Community Health Worker Programs in the National Aging Network

US HHS: Administration for Community Living (ACL)
Federal Government
American Samoa, Guam +4 more
US $200,000 - US $250,000
The Alzheimer's Disease Programs Initiative (ADPI) aims to foster the development of dementia-capable community health worker programs within the National Aging Network. This initiative, supported by the US HHS: Administration for Community Living (ACL), seeks to enhance dementia screening, reduce barriers to care, and improve access to essential services for individuals with dementia and their caregivers. By integrating community health workers into aging services, the program aspires to elevate the quality of life for those affected.
Aging / Gerontology Mental Health & Psychiatric Diseases Health Care Access & Delivery +2 more

The Zero Hunger | Zero Waste Foundation Grant

Kroger Co Zero Hunger Zero Waste Foundation
Corporate
United States
Unspecified amount
The Zero Hunger | Zero Waste Foundation Grant supports nonprofit organizations focused on ending hunger and reducing food waste. Since its inception, the foundation has allocated over $59 million to enhance food security through innovative programs and community engagement. Eligible applicants include 501(c)(3) nonprofits addressing critical needs such as food access, nutrition education, and support for vulnerable populations. This initiative aims to create equitable food systems and ensure that no one goes hungry.
Nutrition & Healthy Eating Food Access & Hunger Food Waste / Composting

Zero Suicide Initiative

Indian Health Service
Federal Government
United States
Unspecified amount
The Zero Suicide Initiative aims to enhance suicide prevention within Indian health systems by implementing the Zero Suicide framework. This program focuses on culturally informed strategies to empower Tribal health systems, fostering leadership, workforce development, and effective suicide risk identification. It emphasizes timely engagement and evidence-based treatment, ensuring continuity of care and quality improvement, ultimately enhancing outcomes for American Indian and Alaska Native individuals at risk for suicide.
Suicide Prevention Native American Services Indigenous Services

Large Grants for Nonprofit Organizations in Kentucky Highlights

Looking for large grants for nonprofit organizations in Kentucky?


Read more about each grant below or start your 14-day free trial to see all large grants for nonprofit organizations in Kentucky recommended for your specific programs.

Last updated: October 5, 2026. Next update: November 1, 2026.

Grant Insights : Large Grants for Nonprofit Organizations in Kentucky

Grant Availability

How common are grants in this category?

Common — grants in this category appear regularly across funding sources.

100+ Large Grants for Nonprofit Organizations in Kentucky grants for nonprofits in the United States, from private foundations to corporations seeking to fund grants for nonprofits.

30 Large Grants for Nonprofit Organizations in Kentucky over $25K in average grant size

21 Large Grants for Nonprofit Organizations in Kentucky over $50K in average grant size

22 Large Grants for Nonprofit Organizations in Kentucky supporting general operating expenses

100+ Large Grants for Nonprofit Organizations in Kentucky supporting programs / projects

600+ Grants on Instrumentl focused on Food Access & Hunger

400+ Grants on Instrumentl focused on Disaster Relief / Humanitarian Aid

Grant Deadline Distribution

Over the past year, when are grant deadlines typically due for Large grants for Nonprofit Organizations in Kentucky?

Most grants are due in the first quarter.

Q1
33.9%
Q2
21.2%
Q3
23.7%
Q4
21.2%

Typical Funding Amounts

What's the typical grant amount funded for Large Grants for Nonprofit Organizations in Kentucky?

Grants are most commonly $8,000.

$500 $500 Min.
$8,000 $8 K Median
$711,767 $711.8 K Average
$40,331,313 $40.3 M Max.

Average Grant Size

What's the typical amount funded for Kentucky?

Grants are most commonly $109,567.

$109,567

Total Number of Grants

What's the total number of grants in Large Grants for Nonprofit Organizations in Kentucky year over year?

In 2024, funders in Kentucky awarded a total of 22,947 grants.

2022 21,785

2023 21,128

2024 22,947

Top Grant Focus Areas

Among all the Large Grants for Nonprofit Organizations in Kentucky given out in Kentucky, the most popular focus areas that receive funding are Education, Philanthropy, Voluntarism & Grantmaking Foundations, and Human Services.

1. Education

2. Philanthropy, Voluntarism & Grantmaking Foundations

3. Human Services

Funding Over Time

How is funding for Large Grants for Nonprofit Organizations in Kentucky changing over time?

Funding has increased by -8.86%.

2022 $1,911,078,212

2023 $2,749,886,359
43.89%

2024 $2,506,220,272
-8.86%

Kentucky Counties That Receive the Most Funding

How does grant funding vary by county?

Jefferson County, Kenton County, and Fayette County receive the most funding.

County Total Grant Funding in 2024
Jefferson County $2,891,811,659
Kenton County $622,235,633
Fayette County $177,080,873
Madison County $78,275,790
Whitley County $69,351,226