Best Large Grants for Nonprofit Organizations in Kentucky

About

Mission, Vision & Values

To enhance our community through philanthropy.

We aspire to co-create diverse, meaningful and innovative charitable giving that yields an exponential positive impact within local communities and beyond.

David Bruce Belcher Fund

About the fund

The David Bruce Belcher Scholarship Fund was established for the training of professionals in nursing, special education, and therapy (physical, speech and occupational) as a legacy of David Bruce Belcher and the caregivers who comforted him. This fund reflects David’s rare spirit and bright love in its support of those who seek to advance their nurturing skills in nursing, therapy, and special education.

This Community Foundation was created by and for the people of Washington County MD, and exists to improve the quality of life for all of our citizens, now and for generations to come, by building community endowments, addressing needs through grant making and providing leadership on key community issues.

Washington County 4-H Livestock/Market Sale Scholarship

Established to support post-secondary scholarships to participants in Washington County 4-H Livestock and Market Sale programs.

The Heiser Program for Research in Leprosy, established by Dr. Victor G. Heiser, focuses on innovative biomedical research to combat leprosy. Since 1975, it has funded over 200 grants totaling more than $20 million, supporting early-career researchers and significant projects. The program aims to enhance diagnostic tools, improve treatments, and implement effective surveillance strategies. With a dedicated Scientific Advisory Committee, it ensures rigorous proposal reviews and fosters collaboration among grantees, ultimately advancing leprosy elimination efforts.

The Partnerships for Opportunity and Workforce and Economic Revitalization (POWER) Initiative aims to revitalize communities impacted by coal industry transitions. This initiative provides funding for projects that diversify local economies, enhance job training, and create new employment opportunities. By fostering collaboration among various stakeholders, the POWER Initiative supports strategic investments that align with regional economic development plans, ensuring a more resilient future for coal-affected areas.

The Gretchen Miller Bowker Scholarship, offered by the Central Indiana Community Foundation, provides financial assistance to women pursuing education in STEM fields. Designed to support tuition, room and board, and related fees, this scholarship aims to empower women in their educational journeys. Eligibility includes demonstrating financial need and enrollment in a qualifying program. With a commitment to building a community of opportunity, this scholarship is a vital resource for aspiring female STEM students.

The Glick Education Award, offered by the Central Indiana Community Foundation, supports educational opportunities for dependents of Gene B. Glick Company employees. Eligible applicants include high school seniors and current post-secondary students. Selection criteria focus on academic achievement, leadership, community involvement, work experience, and financial need. Awards cover tuition, fees, and other educational expenses at accredited institutions. This initiative aims to foster educational attainment within the community, promoting access regardless of race or identity.

The Rod's Tire and Service Scholarship Fund, managed by the Central Kansas Community Foundation, offers $2,500 to assist graduating Marion County high school seniors pursuing higher education or vocational training. The foundation, established in 1994, focuses on enhancing community welfare through charitable giving and emphasizes support for students majoring in agricultural fields. This scholarship aims to empower local youth and strengthen the community by investing in their educational futures.

The National Cancer Institute (NCI) invites applications for studies on mechanisms by which bariatric surgery influences cancer risk. This funding opportunity encourages exploration beyond short-term outcomes like weight loss and diabetes. The goal is to support innovative proof of concept studies, emphasizing feasibility without prior development in the literature. Unpublished data is not allowed, but references from preprints with a DOI are acceptable. Deadlines for applications span from February 2025 to November 2027.

Syndax Pharmaceuticals, Inc.

At Syndax, we are determined to realize a future in which people with cancer live longer and better than ever before. We believe that it takes a community to build a great medicine, and that is why we are working to set the new standard for developing medicines in the field of oncology – one that revolves around collaboration, shared learning, and excellence.

Syndax’s mission is to obtain regulatory approval and commercialize drugs that extend and improve the lives of cancer patients by drawing on the newest scientific research and advances, collaborating with determined problem solvers, and identifying value in overlooked aspects of science.

Educational Funding

At Syndax, we are committed to the goal of supporting objective, balanced and scientifically rigorous education that furthers improvements in science, medicine, and patient care. We accomplish this goal, in part, by providing grants for independent medical education (IME) programs. These can include live, online, and/or enduring programs that educate healthcare providers (HCPs), patients, or caregivers. Programs that are funded via Syndax medical education grants must be primarily dedicated, in both effort and time, to medical, health or scientific topics that are objective, balanced, unbiased, and scientifically rigorous. Medical education grants must never be made with the intent to directly or indirectly reward, influence or encourage the recipient to prescribe, purchase, sell or arrange for any Syndax product.

The Clark and Ruby Baker Foundation Grant aims to support charitable organizations that align with the philanthropic mission of the Baker family, focusing on Methodist-affiliated educational institutions, aid for disadvantaged children, and assistance for the sick in Georgia. The Foundation considers funding for construction projects of educational and medical facilities, ensuring that grants are awarded to meet specific community needs and promote long-term benefits.

The ANCA-Assoc Vasculitis and Granulomatosis with Polyangiitis Fund, established by the HealthWell Foundation, aims to reduce financial barriers for underinsured patients suffering from this rare and serious condition. The fund assists with copays, premiums, and out-of-pocket expenses related to treatment, ensuring that affected individuals have access to necessary medications. With over $1.2 billion in grants awarded since 2004, the foundation has helped over 1.1 million patients access critical healthcare services.

The Fash Foundation Grants aim to support and enhance children's education and the arts in Tarrant County, Texas. The Foundation prioritizes contributions to higher education institutions that align with its mission statement. Grants are awarded to initiatives that promote health and educational advancements in various disciplines including sciences and the arts. The Foundation seeks to foster a nurturing environment for children's educational growth.

The John E. and Ruth L. Fisher Scholarship, provided by the Central Indiana Community Foundation, supports graduating seniors and past graduates of Noblesville High School under the age of 30. This scholarship aims to foster educational opportunities for students demonstrating financial need, covering expenses for various accredited postsecondary programs, including vocational and technical schools. Preference is given to students of color, enhancing diversity and inclusion in education.

The NIDCD Research Career Enhancement Award for Established Investigators (K18) program supports established researchers in enhancing their skills and redirecting their research towards critical areas such as hearing, balance, smell, taste, voice, speech, and language sciences. This program is crucial for fostering innovation and advancing the understanding of these fields. Important deadlines for applications include June 10, 2024, and October 8, 2024, among others.

The NIDCD Research Career Enhancement Award for Established Investigators (K18) supports seasoned researchers in enhancing or redirecting their research through new skills acquisition. This funding opportunity addresses critical questions in hearing, balance, smell, taste, voice, speech, and language sciences. Key deadlines for applications span from June 2024 to February 2027, ensuring ample opportunity for researchers to apply and contribute to these vital fields.

The NIDCD Research Career Enhancement Award (K18) supports established investigators in enhancing or redirecting their research efforts. This program is crucial for acquiring new skills relevant to hearing, balance, smell, taste, voice, speech, and language sciences. Key deadlines for applications span from June 2024 to February 2027, including specific dates for AIDS-related grants, ensuring timely funding opportunities for innovative research.

The Indian Housing Block Grant Competitive Program (IHBG-COMP) for FY 2026 offers competitive grants to eligible recipients under NAHASDA. This program aims to support affordable housing initiatives benefiting low-income Tribal families, enhancing their living conditions and community well-being. Funded by the US HUD's Office of Public and Indian Housing, the IHBG-COMP encourages the development of sustainable housing solutions within Native American communities.

The Greenpoint Foundation Grant aims to enhance community life by supporting organizations that focus on agriculture, food security, education, and community enhancement. Established in 2022, the Foundation accepts grant applications year-round for both general operating budgets and specific projects. Priority is given to 501(c)(3) organizations and local government entities, while faith-based programs are considered on a case-by-case basis. Grant recipients must submit impact reports to ensure continued support.

The NC Hunter and Jumper Association’s Norah Morris Memorial Scholarship Endowment supports individuals pursuing higher education who have engaged in equestrian activities. Open to undergraduates, graduates, and adult re-entry students, the scholarship aims to assist those attending various educational institutions in the United States. Applications for NCCF scholarships will be accepted from December 16, 2025, to March 3, 2026. Be sure to check specific eligibility requirements for each scholarship.

The Joyce Price Johnson’s Samaritan Fund provides scholarships for young people in North Carolina who are exiting foster care or facing poverty. Eligible candidates include undergraduates, graduates, and adult re-entry students attending various accredited institutions. Applications for NCCF scholarships open on December 16, 2025, and close on March 3, 2026. Preference is given to applicants from Wayne County and adjacent areas, ensuring support for those with exceptional financial need.

The Public Health Nursing initiative aims to enhance the health and wellness of American Indian and Alaska Native men by implementing a culturally sensitive case management model. Through this program, Public Health Nurses will provide preventive health services, facilitate access to care, and encourage healthy lifestyle choices. By promoting early identification and management of health issues, the initiative strives to improve overall community health outcomes through targeted, collaborative interventions.

The Sundance Collab's Cultural Impact Residency, honoring Michael Latt, is a six-month online program supporting early-career, underrepresented storytellers focused on social impact. Running from March to August 2026, it offers mentorship, feedback sessions, and resources to eight selected fellows in screenwriting, directing, and documentary filmmaking. This opportunity is designed for works-in-progress, fostering a supportive creative community to inspire and develop impactful narratives.

The Dr. Gary King Sharp Memorial Scholarship, offered by the Central Kentucky Community Foundation, aims to support students with a cumulative GPA of 2.5 or higher. Priority is given to those connected with Hospice services or in the foster care system, and to first-generation college students. This scholarship serves as a vital resource to empower students in their educational pursuits and enhance community life.

The Hyperoxaluria Fund, managed by the HealthWell Foundation, aims to alleviate financial burdens for underinsured patients suffering from hyperoxaluria, a condition characterized by excessive oxalate in urine. This fund assists with prescription drug copays and insurance premiums, providing vital support for treatments. In 2024 alone, HealthWell allocated over $1.2 billion in grants, ensuring access to essential medications for those in need. The organization is committed to improving healthcare access and reducing disparities for affected individuals.

Scholarships

We partner with donors to administer scholarships for students across the state. Most NCCF scholarships open for applications on Dec. 16, 2025, and close on March 3, 2026.

Undergraduates, graduates, medical and professional school students and adult re-entry students who are attending community colleges, four-year universities, career/technical schools, teaching credential programs and graduate, medical or professional schools in the United States are eligible for scholarships offered at NCCF.

Each scholarship has specific eligibility requirements defined by the donor when the scholarship was established. Be sure to read the requirements of each scholarship carefully as directed through the universal application and address those elements as needed in your application.

Grayce Wills MacDonald and Ivan A. MacDonald Endowment

Shall support students who attended high school in Cherokee, Graham, Clay, Swain, Macon, Jackson, Haywood, Buncombe, and Henderson counties, and who are pursuing a college or post-graduate level degree in the field of nutrition with emphasis on the study of natural foods and the vegetarian lifestyle. Scholarships may be based on both need and merit.

The Mantle Cell Lymphoma Fund, managed by the HealthWell Foundation, provides financial assistance to underinsured patients diagnosed with Mantle Cell Lymphoma. The fund covers prescription drug copays and Medicare Part B premiums, with a maximum award of $8,500. Eligible patients must have insurance that covers their medication and meet specific income guidelines. The foundation aims to reduce financial barriers to essential treatments, ensuring that patients receive necessary care without undue financial strain.

The TIRBEE funding opportunity supports federally-recognized Tribes and Tribal Entities in establishing or enhancing Institutional Review Boards. This initiative aims to strengthen the capacity for biomedical research involving human participants within these communities by improving review and oversight capabilities. Eligible organizations are invited to apply, with applications subject to NIH's standard peer-review process to ensure only the most meritorious proposals are considered.