Best Operating Grants for Nonprofits in Kentucky

The Encompass Health Therapy Grant offers up to $50,000 for research on the effectiveness of therapies in inpatient rehabilitation facilities. This funding aims to enhance understanding of neurological impairments and improve patient outcomes through evidence-based practices. Eligible projects must be conducted in the U.S. or Puerto Rico, require a defined research protocol, and adhere to ethical standards. The grant prioritizes studies on therapy impact, implementation science, and caregiver education, contributing to the advancement of rehabilitation care.

The Instrument Donations Program by Music Movement supports children and young adults with Autism and learning differences by providing funding for musical instruments. This initiative fosters self-expression, personal growth, and emotional well-being through music. Grants typically range from $500 to $1,500 and are available to applicants within the United States. The program encourages artistic development and enhances social skills, making a significant impact on the lives of those facing developmental challenges.

Music Movement's Independent Living Initiatives grant supports individuals with Autism and developmental differences in the U.S. Grants, typically ranging from $1,500 to $5,000, aid in various areas including independent living, camps, and continued education. Applicants must be legal guardians of eligible individuals aged 18 and older. The grant portal will reopen for submissions on March 28, 2026, encouraging early review of guidelines to ensure complete applications.

The Community Development Block Grant Program for Indian Tribes and Alaska Native Villages aims to foster the development of viable communities by providing funding for housing, living environments, and economic opportunities, primarily benefiting low- and moderate-income individuals. The program is competitive, offering both single-purpose and imminent threat grants to address urgent public health and safety issues, ensuring that tribes can improve their community welfare effectively.

Single Ventricle Research Fund (SVRF)

Our flagship funding program — the Single Ventricle Research Fund (SVRF) — is an annual research award program that supports foundational studies aimed at improving outcomes for individuals with single ventricle heart disease. By addressing the organ- and multi-organ-level complications and clinical sequelae that drive long-term morbidity and mortality, the SVRF seeks to close critical gaps in understanding and treatment, and accelerate progress toward better, more predictive, and preventative care.

In its sixth cycle, the SVRF welcomes foundational research that is directly relevant to improving outcomes for individuals with single ventricle heart disease.

What Fits

Through the SVRF, Additional Ventures aims to accelerate foundational research that will lead to improved care and new therapeutic opportunities grounded in a mechanistic understanding of single ventricle heart disease.

The 2027 SVRF welcomes research aligned with the focus areas and strategic topics described in the Additional Ventures’ 2026 Research Roadmap. We are particularly interested in proposals that seek to elucidate the mechanisms underlying, prevent, or reverse the interrelated organ- and multi-organ-level sequelae that contribute to long-term morbidity and mortality.

Eligible investigators include postdoctoral fellows or equivalents holding a mentored position. Collaborative proposals will not be accepted through this track.

The Jack Feldt Ambucs Memorial Scholarship, established in 1997, supports students in the Tri-Cities area pursuing a degree in Physical Therapy. Funded by the Grand Haven Area Community Foundation, this scholarship prioritizes applicants demonstrating financial need. It considers college juniors and graduating high schoolers, reflecting the spirit of community and collaboration championed by Ambucs. Eligible candidates need to provide transcripts and additional required documents to complete their application.

About The John A. Hartford Foundation

The John A. Hartford Foundation, based in New York City, is a private, nonpartisan, national philanthropy dedicated to improving the care of older adults. The leader in the field of aging and health, the foundation has three priority areas: creating age-friendly health systems, supporting family caregivers, and improving serious illness and end-of-life care.

Since 1982, The John A. Hartford Foundation has awarded more than $758 million in grants to enhance the health and well-being of older people.

JAHF New Partners Program Call for Proposals:

National Initiatives Advancing Improvements in Care for Older Adults

The John A. Hartford Foundation (JAHF) is entering a new chapter that builds on its work to improve care for older adults and support family caregivers while bringing new organizations, leaders and ideas into its community of grantees and partners.

Through this funding opportunity, JAHF is seeking proposals from organizations that have not previously received a major grant from the foundation.

Proposed initiatives must have a national or multi-site scope and align with at least one of the foundation's three priority areas:

• Age-Friendly Health Systems
• Family Caregiving
• Serious Illness and End-of-Life Care

The Women's Club of Grand Haven Grant, established in 2001, offers scholarships to non-traditional students from the Tri-Cities seeking further education. Funded through community efforts such as an annual Used Book Sale, this grant prioritizes financial need and is open to applicants residing in Northern Ottawa County or those who graduated from local school districts. Preference is given to female applicants aged 21 and older, supporting educational advancement for those whose academic journeys have been interrupted.

The National Trappers Foundation (NTF) offers grants to individuals and organizations for projects related to furbearers. Founded in 1988, NTF supports educational and conservation initiatives that promote the management and restoration of furbearers and natural resources. Grants are available for research, habitat development, and educational programs. Contributions to NTF are tax-deductible, reflecting its commitment to conservation and community engagement.

The Mishler Brown Fund Grant, managed by the Community Foundation of Elkhart County, supports nonprofits dedicated to agriculture and historic preservation. Applications are accepted annually from October 1 to December 31, with funds awarded in January. Organizations must have a 501(c)(3) status but do not need to be located in Elkhart County. The fund honors Helen Mishler's legacy by preserving farming heritage, including her family's historic homestead.

The ASTRO-LUNGevity Residents/Fellows in Radiation Oncology Seed Grant aims to enhance the research careers of residents and fellows focused on radiation oncology, specifically benefiting lung cancer patients. This initiative supports basic, translational, and clinical research endeavors. With a maximum award amount of $50,000 for one year, it provides essential funding to foster innovative projects that can lead to significant advancements in lung cancer treatment.

The Anne and Tony Hillerman Scholarship, part of the New Mexico Press Women Scholarship Fund, supports New Mexico students pursuing undergraduate or graduate degrees in journalism or communications. Established in 2023, the fund promotes ethical journalism and offers networking opportunities through the NMPW Annual Conference. Eligible applicants must be enrolled in a relevant program, provide a portfolio of work, and submit a personal essay detailing their interests and career goals. This scholarship fosters the next generation of communicators and advocates for First Amendment rights.

This funding opportunity invites renewal applications for existing NINDS-supported clinical trial cooperative agreements (U01) that require additional time and resources. The National Institute of Neurological Disorders and Stroke (NINDS) expects applicants to request only what is necessary for trial completion, without introducing new aims. Discussions with NINDS prior to submission are encouraged. Eligible applications must be renewals of previously approved cooperative agreements under specified NIH funding announcements.

The CCRP Initiative invites applications for basic research on chemical threats affecting the nervous system, including chemical warfare agents and toxic industrial chemicals. This funding aims to elucidate toxicity mechanisms, explore new toxic exposure manifestations, and identify targets for therapeutic development. Proposals should generate data relevant to understanding these toxic threats, with applications due by 5 PM local time. Optional Letters of Intent are encouraged 30 days prior to the proposal deadline.

The Melanoma Established Investigator Award offers up to $125,000 annually for two years, aimed at established melanoma researchers or senior researchers transitioning into melanoma research. Eligible applicants include Associate Professors or higher, with both tenured and non-tenured faculty encouraged to apply. U.S. citizenship is not a requirement for this funding opportunity provided by the Melanoma Research Foundation.

The Kiwanis Club of Albuquerque Scholarship Fund, established in 1948, supports graduating seniors from Albuquerque metro area high schools who demonstrate strong academic performance and community service. Annually, one to four scholarships of up to $1,000 are awarded to students pursuing careers in child development and teaching. The fund emphasizes the importance of community involvement and academic excellence, encouraging students to share their career goals and financial needs through an essay as part of their application.

The FY 2027 Service Area Competition (SAC) funding aims to enhance health services in underserved communities across the U.S. by providing grants for comprehensive preventive and primary care. This initiative allows for a competitive selection of service areas, ensuring that health centers can effectively deliver high-quality healthcare. Additional service areas may be announced throughout the year to accommodate changes in service availability, supporting continuous care for those in need.

The New Mexico Veterans Memorial Scholarship, established in 2024, supports graduating high school seniors in New Mexico who embody the Medal of Honor Core Values: Courage, Sacrifice, Integrity, Commitment, Patriotism, and Citizenship. This scholarship encourages students to explore and reflect on these values through a personal essay and community service. Preference is given to students from Albuquerque High Schools, fostering a commitment to excellence and civic duty among the youth.

The Special Wildlife Funds - Duck Stamp Grants program in Canada focuses on the development of waterfowl propagation areas specifically for the Mississippi Flyway. It supports projects in Manitoba and Saskatchewan aimed at enhancing breeding populations of migratory waterfowl. This initiative is funded through the sale of State Migratory Waterfowl Stamps and is targeted at not-for-profit organizations dedicated to the conservation and promotion of wild waterfowl, ensuring sustainable habitats and effective management practices.

The NHLBI SBIR Phase IIB Small Market Awards aim to accelerate the commercialization of innovative technologies targeting heart, lung, blood, and sleep disorders. This funding opportunity addresses the significant gap between SBIR Phase II awards and regulatory approval. Small businesses focusing on rare diseases or young pediatric populations are encouraged to apply, fostering partnerships with investors and advocacy groups to advance projects toward commercialization and regulatory clearance.

The NHLBI SBIR Phase IIB Bridge Awards aim to enhance the commercialization of innovative technologies for heart, lung, blood, and sleep disorders. This program supports small businesses in developing promising projects that have previously received SBIR or STTR Phase II funding, facilitating their journey towards regulatory approval. The initiative emphasizes partnerships between awardees and investors, prioritizing applications that demonstrate a strong potential for clinical relevance and commercialization.

This grant opportunity from the US Department of Health and Human Services, specifically the National Institutes of Health, aims to examine the effectiveness of family navigation models that divert non-urgent mental health concerns from emergency departments. The initiative seeks to enhance mental health service engagement, provide necessary resources, and support families in overcoming barriers to help-seeking. Key deadlines for applications range from February 2025 to October 2027.

The 1890 Institution Teaching, Research, and Extension Capacity Building Grants Program aims to enhance the capabilities of eligible institutions by fostering collaboration with federal and non-federal entities. This initiative supports the White House's commitment to promote excellence at Historically Black Colleges and Universities (HBCUs). By strengthening institutional teaching, research, and extension capacities, the program helps ensure that HBCUs can effectively contribute to innovative solutions in education and community development.

This NOFO aims to enhance research on the effectiveness and implementation of family navigation models that divert non-urgent mental health concerns from emergency departments. It will focus on tools for triaging mental health acuity, engaging families with necessary services, and addressing barriers to help-seeking. Important deadlines for grant applications range from February 2025 to October 2027, with optional Letters of Intent encouraged thirty days prior to each due date.

The Cancer Prevention and Control Programs aim to enhance cancer outcomes by funding partnerships among national, state, territorial, and tribal organizations. These initiatives focus on evidence-based strategies for cancer surveillance, prevention, and control, specifically targeting breast and cervical cancer screening for underserved populations. Through collaboration, the program seeks to improve clinical services and cancer survivorship, ultimately striving towards the vision of 'All People Free of Cancer' by leveraging resources and community involvement.

Alkermes

At Alkermes, we apply our deep neuroscience expertise to develop medicines designed to help people living with complex and difficult-to-treat psychiatric and neurological disorders, including addiction, serious mental illness and sleep disorders. With our portfolio of marketed medicines and investigational pipeline candidates, we seek to make a meaningful difference in the way people manage these chronic diseases. Our patient-inspired science, integrated research strategy, sophisticated development capabilities and specialized commercial infrastructure enable us to pursue the development and commercialization of innovative new medicines, including those for people with conditions that have traditionally been overlooked or stigmatized.

Our greatest strengths at Alkermes are our people and our inherent empathy for patients, families and caregivers. Neurological and psychiatric disorders strike people at the core of who they are and impact many facets of their lives. We work with urgency to develop new treatment options for people living with these conditions.

Pathways APN Research Awards

The Alkermes Pathways Advanced Practice Nurse (APN) Research Awards™ program is designed to empower the advanced practice nursing community by offering funding opportunities that recognize their vital role in evidence-based care and the advancement of mental health research.

The Alkermes Pathways APN Research Awards provide opportunities for individual grants of up to $10,000 per project for licensed psychiatric-mental health nurse practitioners who are actively engaged in clinical, academic, and/or community health settings and are committed to advancing research in schizophrenia or bipolar I disorder.

The BJA FY 2026 Second Chance Act Community-based Reentry Program aims to support community organizations and tribal governments in providing essential mentoring and transitional services for individuals returning from correctional facilities. This initiative targets those assessed as moderate to high risk for recidivism, addressing their needs both pre-and post-release. By fostering successful reintegration into society, the program contributes to public safety and reduces recidivism rates, aligning with the mission of the U.S. Department of Justice.