Best Unrestricted Grants for Nonprofits in Kentucky

The Adapted PE/Activity Program of the Year Award recognizes outstanding community-based initiatives aimed at enhancing the physical capabilities of individuals with disabilities. Organized by SHAPE America, this award highlights programs that provide inclusive physical education and recreational opportunities, ensuring that all participants can engage in healthy, active lifestyles. By showcasing best practices, the award promotes innovation and advocacy for individuals with disabilities, fostering an environment of inclusion and support in physical activity.

The Orthopaedic Physical Therapy Research Grant, funded by the Foundation for Physical Therapy Research, aims to support innovative research that optimizes movement and enhances societal health. With a commitment to addressing health disparities, the foundation will award $40,000 for one or two years to promising researchers. This initiative not only strengthens the physical therapy profession but also contributes to the growing evidence base that underscores the value of physical therapy in various healthcare settings.

The Changing Aging (CA) Grant supports innovative projects aimed at enhancing economic opportunities for older adults and combating ageism. Priorities include advancing digital equity and promoting aging in place for marginalized communities. Funded by Next50, the grant encourages collaboration among nonprofits and requires an equity-focused approach to project design. Organizations may apply for up to three years of funding, with no maximum request limit, although a pre-application call is necessary for larger requests.

The National Institute of Neurological Disorders and Stroke (NINDS) aims to support innovative research for validating therapeutic targets in Alzheimer's Disease-Related Dementias (ADRD). This initiative focuses on overcoming barriers in treatment development by ensuring well-validated targets linked to disease mechanisms. By employing a phased award mechanism, NINDS seeks to enhance the rigor of target validation, facilitating the transition from basic discoveries to clinical applications, ultimately accelerating the development of effective therapeutic strategies.

The Autism Speaks Predoctoral Fellowship aims to support early career autistic scientists in their research endeavors. By providing a two-year fellowship that includes a $40,000 annual award, the program seeks to enhance research training opportunities for promising candidates. Fellows will collaborate with leading mentors in autism research, ensuring that individuals with both academic expertise and lived experience can significantly contribute to advancements in the field. This initiative underscores Autism Speaks' commitment to fostering inclusivity and innovation in autism research.

The FY26 Peer Reviewed Medical Research Program Clinical Trial Award promotes the swift initiation of impactful clinical trials for diseases outlined in specific topic areas. It offers two application categories: Clinical Trial Only and Clinical Trial with Planning Phase, supporting various funding levels based on trial phases and participant counts. The total funding of approximately $94.5M aims to support up to 9 applications, with a maximum award period of 4 years, ensuring significant advancements in medical research.

The Updated National Dislocated Worker Grant Program Guidance addresses the opioid crisis by prioritizing funding for applicants who demonstrate a critical need and have not previously received opioid-related grants. Key updates include eliminating Disaster-Relief Employment as a requirement, emphasizing the inadequacy of workforce resources, and encouraging applications that focus on training qualified professionals in relevant fields. These changes ensure that the program aligns with current policies and effectively supports communities impacted by the opioid epidemic.

The Alpha Sigma Chapter, Alpha Delta Kappa, Inc. Scholarship supports aspiring educators in Saginaw County. Established in 2018, it honors the legacy of women educators dedicated to improving educational excellence. Applicants must have a minimum GPA of 2.5, be full-time students pursuing an undergraduate degree in education, and demonstrate residency in Saginaw County. The scholarship amount ranges from $500 to $4,000, with preference given to previous recipients. This initiative aims to foster the next generation of educators.

The American Business Women’s Association – Saginaw Charter Chapter Scholarship supports women pursuing higher education, fostering personal and professional growth. Established in 1954, this scholarship encourages female students in Saginaw County to achieve their academic goals, particularly those enrolled in career and technical education programs. With awards ranging from $500 to $4,000, it aims to empower women in various fields by providing financial assistance, ensuring that the next generation of businesswomen can thrive and contribute to their communities.

The Leukemia Exploration and Prevention Grant Program (LEAP) aims to advance cancer interception and prevention strategies for patients with RUNX1 familial platelet disorder. This initiative, supported by the American Cancer Society, focuses on understanding the mechanisms behind leukemia development and fostering innovative research leading to effective treatment options. Grants of up to $215,000 per year for four years are available, emphasizing the urgent need for targeted therapies in high-risk populations.

The Leukemia Exploration and Prevention Grant Program (LEAP) aims to advance cancer interception and prevention for patients with RUNX1 familial platelet disorder (RUNX1-FPD). This program supports interdisciplinary research teams investigating the mechanisms of leukemogenesis and innovative treatment strategies. With funding of up to $430,000 per year, LEAP encourages projects focused on both understanding clonal evolution and developing novel therapeutic approaches. The initiative seeks to bridge critical knowledge gaps and provide urgent interventions for high-risk populations.

The Ruth D. Frick Ames Scholarship, established by Robert Ames to honor his wife, supports students pursuing a nursing degree. Managed by the South Dakota Community Foundation, this scholarship aims to ease the financial burden for those aged 18-32 with a GPA of 2.9 or higher. Applicants should demonstrate financial need, strong academic performance, and community involvement. This initiative reflects Ruth's legacy of compassion, service, and commitment to helping others in the nursing field.

The Nels Andersen Scholarship, established by the Saginaw Community Foundation, honors a pioneer in early childhood education. This scholarship supports Saginaw County residents pursuing undergraduate studies in early childhood development, elementary education, or Career and Technical Education (CTE) training, with awards ranging from $500 to $4,000. Eligible applicants must maintain a minimum GPA of 2.5 and can be high school seniors or current college students. Preference is given to full-time students and former participants of Saginaw County Head Start programs.

The NIH is seeking innovative computational approaches to enhance the curation of biomedical research assets at scale. This initiative aims to accelerate access to secure datasets and computational models, facilitating transformative discoveries in biomedical science. Key deadlines for applications range from January 2025 to January 2027, covering standard, renewal, and AIDS-related grants. Applicants are encouraged to submit Letters of Intent 30 days prior to application deadlines to ensure a streamlined review process.

The High-End Instrumentation (HEI) Grant Program, offered by the NIH, invites applications for purchasing or upgrading high-end, specialized instruments, with a minimum award of $750,001 and a maximum of $2,000,000. This program supports NIH investigators aiming to enhance their research capabilities through advanced technologies such as mass spectrometers and electron microscopes. Applications must be submitted by 5:00 pm local time of the applicant organization.

The ASTRO-BCRF Emerging Investigator Award aims to support one early career researcher in breast radiation oncology from underrepresented populations. This initiative by the American Society for Radiation Oncology and the Breast Cancer Research Foundation provides $100,000 for direct costs over one year, emphasizing diversity in the scientific workforce and encouraging eligible individuals to self-identify as part of underrepresented groups in biomedical research.

This funding opportunity invites applications for pilot projects focused on understudied proteins linked to rare diseases. The goal is to generate preliminary data and tools related to these proteins, which belong to druggable families with known rare disease associations. By supporting innovative research, this initiative aims to facilitate the characterization of these proteins, ultimately contributing to advancements in understanding and treating rare diseases.

The Batkoski Family Scholarship honors Frank Batkoski, a dedicated sheet metal worker and Army veteran, by supporting students pursuing Career and Technical Education (CTE). Established by the Saginaw Community Foundation, this scholarship aims to inspire hard work and craftsmanship. With awards ranging from $500 to $4,000, it targets high school seniors from Saginaw County who maintain a minimum GPA of 2.5 and seek to excel in skilled trades. This initiative reflects the growing demand for skilled workers in various trades.

Eleanor & James Latta Jr. Scholarship Fund

Mission Statement

In the spirit of the A. Duie Pyle company focus on supporting people in as many ways as possible, the Latta Scholarship goal is to assist the children or stepchildren of A. Duie Pyle employees to enter into or continue attending an accredited college or technical school. Applicants must be children or stepchildren of A. Duie Pyle employees, should be able to demonstrate academic success, community and/or school contribution and a solid-grasp of future professional plans.

If you are an A. Duie Pyle employee and would like your child to apply for the Latta Scholarship, full details and an application can be accessed here. For any additional questions you can reach out to pylemarketing@aduiepyle.com. or grants@chescocf.org

Background

The Eleanor & James Latta Jr. Scholarship Fund was established through donations from A. Duie Pyle, Inc. and from private donors for the benefit of children of employees of A. Duie Pyle. The fund is administered through the Chester County Community Foundation, and award winners are selected by the fund's scholarship committee, none of whom work at A. Duie Pyle.

Eleanor Pyle was Duie Pyle's daughter, and in 1942 she married James Latta, Jr. At the time, Mr. Latta was serving his country in the U.S. Army. Shortly after the wedding, Mr. Latta shipped out and served in the China-Burma-India Theater, and did not return home until April of 1945. Beginning in 1946, Jim Latta worked alongside Duie Pyle as the company continued to grow.

As Mr. Pyle's health declined in the early 1960's, Mr. Latta assumed the decision making for the future of the company. Mr. Latta led Pyle through rapid expansion, diversification, and a Teamster strike, and Pyle's resulting decertification. Throughout his leadership, Eleanor, his wife of 52 years, was by his side and involved in the company's activities. As Mr. Latta's health problems began to compound during 1985, much of the responsibility for the day to day decision making was transferred to Mr. and Mrs. Latta's three sons: Jimmy, Duie, and Peter. Mr. Latta remained a guiding force for his sons until his passing on June 16, 1995. Mrs. Latta continued as the matriarch of the company for many more years, until her passing on September 29, 2011.

The company experienced tremendous growth and solidified its identity as an outstanding place to work under the leadership of Eleanor and James Latta, Jr. They were always big proponents of education, and this scholarship fund is in memory of their tremendous contribution, and for the benefit of the employees of A. Duie Pyle, who they both so dearly respected and valued.

In 2013, shortly before his retirement, Pyle's President, Steve O'Kane, started the Eleanor & James Latta Jr. Scholarship Fund for the benefit of children of employees of A. Duie Pyle, in memory of Eleanor & James Latta Jr.

The ASTRO-LUNGevity Residents/Fellows in Radiation Oncology Seed Grant aims to advance the research careers of residents and fellows focusing on radiation oncology and its impact on lung cancer treatment. This $50,000 award supports innovative basic, translational, and clinical research projects. A no-cost extension may be granted at ASTRO and LUNGevity's discretion, but the total project duration cannot exceed two years.

The Buena Vista Township Lions Club Scholarship, managed by the Saginaw Community Foundation, offers financial assistance to high school seniors pursuing undergraduate degrees or career and technical education. Applicants must maintain a minimum GPA of 2.0 and be residents of Buena Vista Township or Saginaw County. This scholarship ranges from $500 to $4,000, aiming to support students in skilled trades, highlighting the growing demand for workforce-ready individuals in various technical fields.

Community Collaboration Challenge

Applications for the 2026 Community Collaboration Challenge are now open! With support from the Leon Lowenstein Foundation, the Challenge provides $5,000 – $10,000 awards to communities and is designed to support collaboration that expands and pilots evidence-based K-12 student supports in the form of high-impact tutoring, mentoring, student success coaching, postsecondary transition coaching, and/or wraparound/integrated student supports.

The Igor Gorin Memorial Award, established in 1993 by the Community Foundation for Southern Arizona, honors the legacy of Igor Gorin by supporting aspiring vocalists. With $382,000 awarded to 49 young talents, this fund provides unrestricted financial assistance for coaching, travel, and auditions. The 2026 award offers up to $12,000, aimed at those overcoming financial barriers to pursue operatic careers, ensuring that exceptional vocalists can thrive in their artistic journeys.

The Breast Cancer Alliance offers Exceptional Project Grants aimed at enhancing survival rates and quality of life for individuals affected by breast cancer. This grant, amounting to $100,000 over one year, supports innovative research and projects in the contiguous United States. Eligible applicants include clinical doctors and research scientists at any career stage. The funding covers salary and project costs, with indirect costs capped at 8% of direct costs, ensuring comprehensive support for impactful research.

Keith Brabant Music Scholarship Application

The Keith Brabant Music Scholarship committee is interested in finding and assisting young aspiring musicians who are willing to put in the hard work to pursue their talent, but are in need of financial help. This scholarship is to assist those with a documented financial need. Monies may be used for a broad range of music related activities (college, lessons, instruments, books, summer music camp, etc.). If the money is for lessons, instruments, or other specific items, please include information on the costs below; payment may be made directly to provider.

The American Epilepsy Society offers Postdoctoral Research Fellowships to support trainees conducting research on epilepsy's causes, treatment, and consequences. These fellowships provide up to $49,000 for stipend and benefits, $1,000 for travel to the AES annual meeting, and complimentary membership. Proposals can be basic, translational, or clinical research, and the number of awards depends on available funding.

This grant aims to enhance applied regulatory science research for the evaluation and treatment of cardiotoxicity associated with oncology therapeutics. The initiative will facilitate collaboration with the FDA to develop effective methodologies and solutions, ensuring that research outcomes are directly relevant to regulatory decision-making. Key activities include regular communication with funded investigators and a focus on improving detection and management of cardiotoxicity, ultimately leading to impactful publications and presentations.