Best Large Grants for Nonprofit Organizations in Maine

The Sarah K. de Coizart Perpetual Charitable Trust, established in 1992, focuses on supporting species conservation and blindness-related services in the Northeast United States. Grants range from $20,000 to $75,000 for conservation projects and $20,000 to $50,000 for blindness initiatives. Priority is given to endangered species and innovative research efforts. Organizations must be IRS-designated public charities. The Trust does not fund individuals or matching gifts, ensuring support goes directly to impactful projects.

The Henry L.P. Schmelzer College Transitions Scholarship provides essential financial support to nontraditional adult learners in Maine. Aimed at residents facing financial need, this scholarship facilitates access to various educational pathways, including two- and four-year colleges, certificate programs, and self-directed learning. Named after a notable advocate for education, the fund encourages adults to pursue their academic goals, ensuring they receive the necessary resources to overcome barriers and thrive in their educational journeys.

The James and Marilyn Rockefeller Scholarship supports Maine residents over 18 who seek educational opportunities that will transform their lives. Designed for nontraditional students, it offers financial assistance for various training programs, including college and certificate courses. Applicants must demonstrate determination and have a clear plan for their education. This scholarship aims to alleviate the financial burden of pursuing higher education, empowering adult learners to achieve their academic goals.

The Land for Communities (L4C) Grant, established by the Maine Community Foundation, supports community land projects that enhance relationships to land for underserved populations in Maine. With funding options up to $50,000 for land acquisition and $25,000 for other land-based projects, the grant aims to empower communities by expanding access and promoting stewardship. This initiative prioritizes projects that engage local populations and focus on land return and community agriculture.

The Fence Authority Scholarship offers a $1,000 award to students pursuing a bachelor’s degree in fields that enhance community beautification, such as architecture, civil engineering, and environmental sciences. Applicants must be U.S. citizens, enrolled full-time, and involved in community service. This scholarship aims to empower students to contribute positively to society while furthering their education in impactful disciplines.

The JFNY Grant for Arts & Cultural Exchange supports U.S. non-profit organizations aiming to enhance understanding of Japanese arts and culture. Eligible projects include performances, workshops, and exhibitions, with priority given to those with additional funding and in areas with limited access to cultural events. Applications must be submitted at least one month prior for online projects and three months for others. The grant covers expenses like travel, publicity, and artist fees, and is reimbursed upon project completion.

The ASHRAE Region I Setty Family Foundation Scholarship offers a one-year award for undergraduate mechanical or architectural engineering students attending institutions in ASHRAE Region I or those who graduated from high schools in the area. Eligible candidates must maintain a minimum GPA of 3.0 and meet specific program criteria, promoting excellence in HVAC&R education. This scholarship supports future leaders in the field, ensuring a sustainable built environment.

The Bank of America Charitable Foundation focuses on supporting organizations that empower communities through basic needs, income creation, and stable housing. By investing in health and job opportunities, they aim to enhance economic mobility for low- and moderate-income families. Their partnerships target vulnerable populations, ensuring equitable access to resources that foster community vitality and resilience. This initiative emphasizes the importance of stable housing as a foundation for personal and communal growth.

The Wolf Kahn Foundation Grant supports nonprofit organizations focused on visual arts, enhancing education and artist careers through exhibitions and residencies. Grants range from $5,000 to $15,000, prioritizing projects that promote social justice and environmental awareness. Eligible applicants must be 501(c)(3) organizations located in specific regions, while school-based programs and certain other entities are excluded. This initiative honors Wolf Kahn's legacy by fostering artistic collaboration and public engagement.

The American Electric Power Foundation provides grants to 501(c)(3) organizations focused on educational improvement, particularly in STEM fields, and basic human services such as hunger and housing. Organizations must operate within AEP's service territory or have a broader beneficial purpose. The Foundation also supports social justice initiatives and environmental protection efforts. Eligible applicants must affirm compliance with anti-discrimination policies and demonstrate commitment to diversity and inclusion.

The Maine Section of the Society of Women Engineers (SWE) offers the SWE Maine Scholarship to encourage high school senior girls in Maine to pursue engineering education. With over 40 years of commitment, this scholarship aims to support future engineers and promote the Society of Women Engineers. In 2025, eligible applicants can receive over $1,000, helping them embark on a successful academic journey in engineering or engineering technology.

The William Bingham 2nd Scholarship for Adult Learners Fund supports Maine's nontraditional students pursuing higher education. Established in 2017 to honor philanthropist William Bingham, this scholarship alleviates financial burdens for adult learners attending accredited colleges, universities, or training programs. Eligible applicants must be Maine residents and meet specific criteria, such as being over 25 or working full-time. The scholarship emphasizes the importance of preparation and commitment to education, making it a valuable resource for those seeking to advance their skills and knowledge.

The Margaret E. Burnham Charitable Trust supports nonprofit organizations in Maine through grants in five key areas: Community/Social Services, Medical, Educational, Arts/Culture, and Environment. Each area receives a designated percentage of funds, emphasizing the trust's commitment to addressing local needs. Eligible organizations must be 501(c)(3) tax-exempt and operate within Maine. Notably, the trust does not fund multi-year requests or grants to individuals or religious organizations.

The NESOT Paper of the Year Award, presented by the Northeast Society of Toxicology, recognizes outstanding publications in toxicology by graduate students or postdoctoral fellows. Eligible applicants must be NESOT members affiliated with institutions in Connecticut, Maine, Massachusetts, New Hampshire, New York, Rhode Island, or Vermont. Papers must be published or in press in peer-reviewed journals between December 1, 2024, and November 30, 2025. The award includes a certificate and a $1,000 honorarium.

The Corporal Eugene Cole Scholarship Fund, established by the Maine Community Foundation in 2019, honors the legacy of Eugene Cole by supporting Maine residents pursuing post-graduate studies in law enforcement. This scholarship aims to assist individuals seeking careers such as police officers, forensic specialists, and cybercrime analysts, among others. The Maine Community Foundation has a long history of providing educational support, awarding over $3 million annually across nearly 700 scholarship funds.

The Ashley Bryan Fellowships, offered by the Maine Writers and Publishers Alliance, provide crucial support to emerging Maine writers facing barriers in professional literary spaces. Named in honor of the acclaimed artist Ashley Bryan, these fellowships foster creativity and community among writers from marginalized backgrounds, including Black writers and members of Native communities. Participants receive free membership, workshops, and resources to enhance their literary skills, promoting equity and inclusion in the literary world.

The Lloyd G. Balfour Foundation, established in 1973, focuses on educational support for underserved populations in New England. It offers scholarships for employees of the Balfour Company and their families, as well as funding for organizations that provide educational services in Attleboro and surrounding areas. The Foundation prioritizes programs aimed at college readiness and success, particularly for first-generation and low-income students, and encourages multi-year funding requests to enhance nonprofit sustainability.

The Ernest Morgan Memorial Scholarship, managed by CommunityGiving, supports central Minnesota student athletes and leaders to pursue higher education outside their home states. This scholarship aims to expand students' horizons and experiences, with a total award of $5,000 available. Open to high school seniors from specific schools, applicants are encouraged to apply online and demonstrate their leadership or athletic skills. This initiative enhances educational opportunities and fosters personal growth among local youth.

The Extension Risk Management Education (ERME) Competitive Grants: Exploratory Projects aim to enhance agricultural producers' economic viability through innovative risk management education. Funded by the University of Delaware, these grants offer up to $10,000 for projects that address emerging risk topics or support producer workshops. With an 18-month duration from April 2026 to September 2027, this initiative encourages the development of new educational approaches to better serve the needs of farmers and ranchers.

The Allison Keller Education Technology Grant Program, established by the Doug Flutie, Jr. Foundation for Autism, aims to bridge the technological gap for schools and organizations supporting individuals with autism. Since 2012, over $820,000 has been awarded to enhance learning through technology, including iPads and apps. Eligible applicants include 501(c)(3) organizations and public schools in Massachusetts and surrounding New England states, with one program per district receiving funding annually.

Asia-Pacific Network for Global Change Research

The Asia-Pacific region, home to over half the world's population, faces challenges due to its development goals, which strain natural resources, communities, and cultural heritage. These issues are exacerbated by adverse environmental changes. While research has shed light on these problems, it's clear that more challenges lie ahead. The Asia-Pacific Network for Global Change Research (APN) is well-positioned to generate new knowledge and solutions for these evolving global change and sustainability issues by supporting collaborative research and scientific capacity development activities, particularly those aimed at training the next generation of early career professionals.

APN 2025 Call for Proposals: CAPaBLE Programmes

CAPaBLE, our scientific capacity development programme, aims to enhance the capacity of scientists, policymakers and practitioners to assess global change issues, and explore options to resolve issues towards achieving sustainability. Through CAPaBLE, we support activities that enhance capacity at individual, organizational and systemic levels.

Activities of interest under the CAPaBLE Programme

APN supports CAPaBLE activities that enhance existing capacities of developing countries at three levels of individual-based capacity development; group, organisation, network-based capacity development; and societies, governance, and system level capacity development. APN accepts CAPaBLE proposals that engage 1 or more member/approved countries. Proposals must address one or more of the following activities:

SCIENTIFIC CAPACITY DEVELOPMENT ACTIVITIES that promote the following approaches related to one or more of the six thematic areas of APN:

• Utilising and strengthening existing capacity, 
• Creating opportunities to use/instil capacity, 
• Developing new capacity through innovative approaches.

AWARENESS-RAISING AND DISSEMINATION activities through policy- and decision-making communities, civil society, and/or the general public.

SCIENCE-POLICY interfacing in the context of the priority topics.

CAPACITY DEVELOPMENT PARTNERSHIP ACTIVITIES that contribute to the capacity development components of the evolving global change arena, including the UNFCCC Paris Agreement, IPCC, IPBES, post-2015 Sustainable Development Goals, Sendai Framework for Disaster Risk Reduction, and the UN Decade of Ocean Science, and ongoing and new global change and sustainability research programmes.

Activities geared towards using SCIENCE COMMUNICATION to disseminate knowledge generated from projects, particularly to non-science audiences.

About PCORI

PCORI funds patient-centered comparative clinical effectiveness research (CER).

Our Mission

PCORI helps people make informed healthcare decisions, and improves healthcare delivery and outcomes, by producing and promoting high-integrity, evidence-based information that comes from research guided by patients, caregivers, and the broader healthcare community.

Broad Pragmatic Studies PCORI Funding

The Patient-Centered Outcomes Research Institute (PCORI) intends to issue a Broad Pragmatic Studies (BPS) PCORI Funding Announcement (PFA), seeking to fund patient-centered comparative clinical effectiveness research (CER) projects. 

Research Initiative Highlights

CER compares at least two available health treatments, services or care delivery strategies. PCORI seeks proposals that compare clinical interventions (e.g., pharmacological and nonpharmacological treatments, screening and diagnostic approaches) and healthcare delivery system interventions (e.g., workforce, technologies, healthcare service delivery designs) to evaluate potential benefits and harms of different treatment and care delivery options, thus generating evidence that empowers patients, caregivers and the broader healthcare community with information to make informed choices that reflect their needs and preferences.

Special Areas of Emphasis

For Cycle 2 2026, PCORI is particularly interested in submissions that address the following Special Areas of Emphasis (SAE) within the BPS funding opportunity. The purpose of identifying these SAEs is to encourage submissions to these areas, rather than limiting submissions to these topics. Applicants addressing one of the below SAEs should identify the area that is best associated with their research approach:  

• Addressing Obesity
• Diabetes Prevention, Care and Treatment
• Management of Urogynecological and Pelvic Pain
• Pain Management for Individuals Living With Sickle Cell Disease

In PCORI-funded research, patients and other research partners are expected to meaningfully contribute their lived experience or professional expertise to ensure studies are patient-centered, relevant and useful for healthcare decision making. Applicants must address PCORI’s Foundational Expectations for Partnerships in Research — an evidence-based framework supported by tools and resources to guide effective engagement strategies. Applicants are also strongly encouraged to consider the inclusion of a broad range of patient-centered burdens and economic outcomes. 

Broad Pragmatic Studies PFA: Category 1, Category 2 and Category 3 Study Specifications

PCORI will commit up to $120 million in direct costs through this funding opportunity. This funding opportunity contains three categories for funding:

• Category 1: Category 1 will support research projects with direct costs up to and including $5 million.

• Category 2: Category 2 will support research projects with direct costs greater than $5 million and up to a maximum of $12 million. Applications for funding under Category 2 will be required to provide additional information in the Letter of Intent (LOI) and application to justify the size and scope of the proposed research projects and to explain how additional funds are necessary with respect to the scale, scope and complexity of personnel and material resources needed to address the research question.

• Category 3: Category 3 will support research projects with direct costs up to $12 million that utilize PCORnet® to conduct observational studies and/or pragmatic trials that are national in scale. Category 3 PCORnet Studies® must include two or more Clinical Research Networks and share study progress, performance metrics and best practices with the network to promote continuous learning and improvement. PCORnet Studies® will leverage the PCORnet Common Data Model® as appropriate. Additional details about Category 3 can be found on the PCORI website.  

The Patient-Centered Outcomes Research Institute (PCORI) intends to issue a Broad Pragmatic Studies (BPS) PCORI Funding Announcement (PFA) on Aug. 4, 2026, seeking to fund high-impact, patient-centered comparative clinical effectiveness research (CER) projects. This preannouncement provides potential applicants additional time to identify collaborators; obtain patient and stakeholder input on potential studies; and develop responsive, high-quality applications. 

Patient-centered CER compares at least two available health treatments, services or care delivery strategies. PCORI seeks proposals that compare clinical interventions (e.g., pharmacological and nonpharmacological treatments, screening and diagnostic approaches) and healthcare delivery system interventions (e.g., workforce, technologies, healthcare service delivery designs) to evaluate potential benefits and harms of different treatment and care delivery options, thus generating evidence that empowers patients, caregivers and the broader healthcare community with information to make informed choices that reflect their needs and preferences. 

The Aimlee Laderman Student Grant, offered by the Society for Ecological Restoration, supports emerging professionals in ecological restoration research. Established in 2005, this biennial grant is dedicated to Aimlee Laderman, a founding member of SER-NE. Applicants must be enrolled in or recently graduated from a relevant program, and their work must be completed by August 30, 2024. The next application cycle is anticipated in early 2025.

About 

The National Sea Grant College Program was established by the U.S. Congress in 1966 and works to create and maintain a healthy coastal environment and economy. The Sea Grant network consists of a federal/university partnership between the National Oceanic and Atmospheric Administration (NOAA) and 34 programs in every coastal and Great Lakes state, Puerto Rico, and Guam.

The Northeast Sea Grant Consortium is a regional collaboration that includes 8 Sea Grant programs in 7 Northeast states: Connecticut, Maine, Massachusetts, New Hampshire, New York, Rhode Island, and Vermont.

The Northeast Sea Grant Consortium collaborates on regional initiatives in research, education, extension, and communications—leveraging local expertise to create regional benefits and accomplishments.

American Lobster Initiative (ALI) Collaborative Research

The Sea Grant American Lobster Initiative is pleased to announce funding to support new collaborative research projects that closely align with emerging lobster industry and management needs. This request for proposals (RFP) adds to the substantial breadth of previous ALI-funded research by prioritizing projects that create “actionable science” (outputs and findings of the scientific process are useful to and usable by end-user communities) through the co-creation of information and/or products. 

To reach this goal, the ALI seeks to support collaborative research practices, the sharing of knowledge, expertise, and resources/capacities amongst the many people who comprise the American lobster industry. Projects must be developed and led by collaborative research teams that include at least one fishing industry representative, such as a commercial fisherman or a representative from a commercial fishing business, including cooperatives, dealers and processors. This call emphasizes research conducted with and for the industry, offering an exciting opportunity to support and elevate industry-research-management partnerships to address current ecological, regulatory, and socio-economic challenges faced by the American lobster fishery.

The Sea Grant American Lobster Initiative invites proposals for collaborative research projects to be funded from December 1, 2026 to December 31, 2028. Projects can be up to two years in duration, with a recommended duration of no less than 18 months. 

This opportunity is designed to support collaborative research conducted by those affiliated with the American lobster industry (including shoreside supply chain businesses), and any public or private higher education institution, municipal, state, federal, or tribal entity, research laboratory, or other community or non-profit institution. This opportunity is not open to single investigator proposals.

A total of $400,000 is available to support up to 8 two-year project awards. Project budgets cannot exceed $100,000 (including all direct and indirect costs), and must include non-federal cost share is required for this competition. See full RFP for guidance.

Marr Anderson Family Foundation

Founded in 2016, The Marr-Anderson Family Foundation is inspired to serve and strengthen families and their communities. John and Rebecca Marr have Maine roots as part of their heritage and have been long time residents of Falmouth, Maine. They believe in the importance of compassion, determination and encouragement. Their family foundation is a continuation of their philanthropic path to serve in the areas of health, education and catastrophic events. The foundation is a family collaboration, which includes daughters, Stephanie, Andrea and Jennifer.

The Marr-Anderson Family Foundation’s mission is to promote education, health and offer compassionate support during times of crisis. In support of their mission, the Marr-Anderson Family Foundation provides philanthropic support to public charitable organizations for the purpose of encouraging education and health. In addition, the Marr-Anderson Family Foundation offers encouragement for individuals to fulfill their dreams and provides philanthropic aid during difficult times when one’s dreams may be put on hold.

Marr-Anderson Family Foundation Grant

The Marr-Anderson Family Foundation provides philanthropic support to public charitable organizations for the purpose of encouraging education and health. The Marr-Anderson Family Foundation provides grants only to public charitable organizations that fall within Section 501(a)(1) or 501(a)(9) and that further these purposes.

The Marr-Anderson Family Foundation supports non-profit organizations that align with our mission to promote education, health and offer compassionate support during times of crisis. The foundation’s objective is to support organizations that further these efforts.

The National Forest Foundation's Matching Awards Program connects communities to forests by funding stewardship activities that promote engagement with National Forests and nearby public lands. This program aims to create lasting impacts, ensuring that all communities can benefit from the rich resources of these natural areas. By supporting various projects, the program fosters a deeper relationship between people and the environment, ultimately enhancing conservation efforts and community well-being.