Best Large Grants for Nonprofit Organizations in Maine

The Ernest Morgan Memorial Scholarship, managed by CommunityGiving, supports central Minnesota student athletes and leaders to pursue higher education outside their home states. This scholarship aims to expand students' horizons and experiences, with a total award of $5,000 available. Open to high school seniors from specific schools, applicants are encouraged to apply online and demonstrate their leadership or athletic skills. This initiative enhances educational opportunities and fosters personal growth among local youth.

The Ashley Bryan Fellowships, offered by the Maine Writers and Publishers Alliance, provide crucial support to emerging Maine writers facing barriers in professional literary spaces. Named in honor of the acclaimed artist Ashley Bryan, these fellowships foster creativity and community among writers from marginalized backgrounds, including Black writers and members of Native communities. Participants receive free membership, workshops, and resources to enhance their literary skills, promoting equity and inclusion in the literary world.

The Lloyd G. Balfour Foundation, established in 1973, focuses on educational support for underserved populations in New England. It offers scholarships for employees of the Balfour Company and their families, as well as funding for organizations that provide educational services in Attleboro and surrounding areas. The Foundation prioritizes programs aimed at college readiness and success, particularly for first-generation and low-income students, and encourages multi-year funding requests to enhance nonprofit sustainability.

The US Department of Health & Human Services, through the NIH, invites applications for innovative approaches to implement SBIRT/P for addressing alcohol, tobacco, and other drug use in adults facing health disparities. This funding opportunity encourages research that tests screening, brief interventions, and referrals for treatment or prevention services. Applications are due on specified deadlines from February 2024 through March 2027, fostering collaboration with healthcare and community partners to enhance public health outcomes.

About 

The National Sea Grant College Program was established by the U.S. Congress in 1966 and works to create and maintain a healthy coastal environment and economy. The Sea Grant network consists of a federal/university partnership between the National Oceanic and Atmospheric Administration (NOAA) and 34 programs in every coastal and Great Lakes state, Puerto Rico, and Guam.

The Northeast Sea Grant Consortium is a regional collaboration that includes 8 Sea Grant programs in 7 Northeast states: Connecticut, Maine, Massachusetts, New Hampshire, New York, Rhode Island, and Vermont.

The Northeast Sea Grant Consortium collaborates on regional initiatives in research, education, extension, and communications—leveraging local expertise to create regional benefits and accomplishments.

American Lobster Initiative (ALI) Collaborative Research

The Sea Grant American Lobster Initiative is pleased to announce funding to support new collaborative research projects that closely align with emerging lobster industry and management needs. This request for proposals (RFP) adds to the substantial breadth of previous ALI-funded research by prioritizing projects that create “actionable science” (outputs and findings of the scientific process are useful to and usable by end-user communities) through the co-creation of information and/or products. 

To reach this goal, the ALI seeks to support collaborative research practices, the sharing of knowledge, expertise, and resources/capacities amongst the many people who comprise the American lobster industry. Projects must be developed and led by collaborative research teams that include at least one fishing industry representative, such as a commercial fisherman or a representative from a commercial fishing business, including cooperatives, dealers and processors. This call emphasizes research conducted with and for the industry, offering an exciting opportunity to support and elevate industry-research-management partnerships to address current ecological, regulatory, and socio-economic challenges faced by the American lobster fishery.

The Sea Grant American Lobster Initiative invites proposals for collaborative research projects to be funded from December 1, 2026 to December 31, 2028. Projects can be up to two years in duration, with a recommended duration of no less than 18 months. 

This opportunity is designed to support collaborative research conducted by those affiliated with the American lobster industry (including shoreside supply chain businesses), and any public or private higher education institution, municipal, state, federal, or tribal entity, research laboratory, or other community or non-profit institution. This opportunity is not open to single investigator proposals.

A total of $400,000 is available to support up to 8 two-year project awards. Project budgets cannot exceed $100,000 (including all direct and indirect costs), and must include non-federal cost share is required for this competition. See full RFP for guidance.

The Patient-Centered Outcomes Research Institute (PCORI) intends to issue a Broad Pragmatic Studies (BPS) PCORI Funding Announcement (PFA) on Aug. 4, 2026, seeking to fund high-impact, patient-centered comparative clinical effectiveness research (CER) projects. This preannouncement provides potential applicants additional time to identify collaborators; obtain patient and stakeholder input on potential studies; and develop responsive, high-quality applications. 

Patient-centered CER compares at least two available health treatments, services or care delivery strategies. PCORI seeks proposals that compare clinical interventions (e.g., pharmacological and nonpharmacological treatments, screening and diagnostic approaches) and healthcare delivery system interventions (e.g., workforce, technologies, healthcare service delivery designs) to evaluate potential benefits and harms of different treatment and care delivery options, thus generating evidence that empowers patients, caregivers and the broader healthcare community with information to make informed choices that reflect their needs and preferences. 

The Public Higher Education Impact Award, offered by the Maine Education Association, recognizes individuals or groups that have significantly improved public higher education in Maine through advocacy and community leadership. This award honors those who support faculty and staff in their efforts to provide quality education. The MEA is committed to ensuring equity and empowering educators, making this award a vital acknowledgment of dedication and impact in the educational landscape.

About PCORI

PCORI funds patient-centered comparative clinical effectiveness research (CER).

Our Mission

PCORI helps people make informed healthcare decisions, and improves healthcare delivery and outcomes, by producing and promoting high-integrity, evidence-based information that comes from research guided by patients, caregivers, and the broader healthcare community.

Broad Pragmatic Studies PCORI Funding

The Patient-Centered Outcomes Research Institute (PCORI) intends to issue a Broad Pragmatic Studies (BPS) PCORI Funding Announcement (PFA), seeking to fund patient-centered comparative clinical effectiveness research (CER) projects. 

Research Initiative Highlights

CER compares at least two available health treatments, services or care delivery strategies. PCORI seeks proposals that compare clinical interventions (e.g., pharmacological and nonpharmacological treatments, screening and diagnostic approaches) and healthcare delivery system interventions (e.g., workforce, technologies, healthcare service delivery designs) to evaluate potential benefits and harms of different treatment and care delivery options, thus generating evidence that empowers patients, caregivers and the broader healthcare community with information to make informed choices that reflect their needs and preferences.

Special Areas of Emphasis

For Cycle 2 2026, PCORI is particularly interested in submissions that address the following Special Areas of Emphasis (SAE) within the BPS funding opportunity. The purpose of identifying these SAEs is to encourage submissions to these areas, rather than limiting submissions to these topics. Applicants addressing one of the below SAEs should identify the area that is best associated with their research approach:  

• Addressing Obesity
• Diabetes Prevention, Care and Treatment
• Management of Urogynecological and Pelvic Pain
• Pain Management for Individuals Living With Sickle Cell Disease

In PCORI-funded research, patients and other research partners are expected to meaningfully contribute their lived experience or professional expertise to ensure studies are patient-centered, relevant and useful for healthcare decision making. Applicants must address PCORI’s Foundational Expectations for Partnerships in Research — an evidence-based framework supported by tools and resources to guide effective engagement strategies. Applicants are also strongly encouraged to consider the inclusion of a broad range of patient-centered burdens and economic outcomes. 

Broad Pragmatic Studies PFA: Category 1, Category 2 and Category 3 Study Specifications

PCORI will commit up to $120 million in direct costs through this funding opportunity. This funding opportunity contains three categories for funding:

• Category 1: Category 1 will support research projects with direct costs up to and including $5 million.

• Category 2: Category 2 will support research projects with direct costs greater than $5 million and up to a maximum of $12 million. Applications for funding under Category 2 will be required to provide additional information in the Letter of Intent (LOI) and application to justify the size and scope of the proposed research projects and to explain how additional funds are necessary with respect to the scale, scope and complexity of personnel and material resources needed to address the research question.

• Category 3: Category 3 will support research projects with direct costs up to $12 million that utilize PCORnet® to conduct observational studies and/or pragmatic trials that are national in scale. Category 3 PCORnet Studies® must include two or more Clinical Research Networks and share study progress, performance metrics and best practices with the network to promote continuous learning and improvement. PCORnet Studies® will leverage the PCORnet Common Data Model® as appropriate. Additional details about Category 3 can be found on the PCORI website.  

Foundation for Children with Intellectual and Developmental Disabilities

The FCIDD was founded for the purpose of providing support to organizations that serve individuals with intellectual and developmental disabilities.

Mission Statement: The Foundation supports organizations which enhance the lives of persons with intellectual and developmental disabilities by promoting research, projects, education and advocacy. 

Nonprofit Project Grants

The Foundation for Children with Intellectual and Developmental Disabilities (FCIDD) funds 501(c)(3) organizations working with individuals with intellectual and developmental disabilities of all ages, primarily in the states of Maine, New Hampshire, Vermont, Massachusetts, Rhode Island, Connecticut, New York, New Jersey, Pennsylvania, Ohio, West Virginia, Delaware, Maryland, the District of Columbia, and Virginia. 

Funding Priorities

• Grants will be awarded for the purpose of primarily benefiting, including, or increasing accessibility for individuals with intellectual or development disabilities.
• Grants may be awarded for scholarships or training personnel in the care and education of individuals with developmental and/or intellectual disabilities. 
• Grants shall mainly be distributed to a Charity whose primary purpose or whose project is to support individuals with intellectual or developmental disabilities. A Charity which has a project to benefit individuals with developmental or intellectual disabilities based on financial need shall be awarded the grant money based upon its own objective criteria and without any special preference to members of Civitan or members of their family.

Grant Categories

A grant application typically fits into one of the following categories: Accessibility & Engagement; Educational Spaces; Program Area Improvements; Outreach and Education 

Accessibility & Engagement

For museums, parks, other public spaces without a specific I/DD focus wanting to make property or equipment improvements and additions to better include visitors with I/DD.

Asia-Pacific Network for Global Change Research

The Asia-Pacific region, home to over half the world's population, faces challenges due to its development goals, which strain natural resources, communities, and cultural heritage. These issues are exacerbated by adverse environmental changes. While research has shed light on these problems, it's clear that more challenges lie ahead. The Asia-Pacific Network for Global Change Research (APN) is well-positioned to generate new knowledge and solutions for these evolving global change and sustainability issues by supporting collaborative research and scientific capacity development activities, particularly those aimed at training the next generation of early career professionals.

APN 2025 Call for Proposals: CAPaBLE Programmes

CAPaBLE, our scientific capacity development programme, aims to enhance the capacity of scientists, policymakers and practitioners to assess global change issues, and explore options to resolve issues towards achieving sustainability. Through CAPaBLE, we support activities that enhance capacity at individual, organizational and systemic levels.

Activities of interest under the CAPaBLE Programme

APN supports CAPaBLE activities that enhance existing capacities of developing countries at three levels of individual-based capacity development; group, organisation, network-based capacity development; and societies, governance, and system level capacity development. APN accepts CAPaBLE proposals that engage 1 or more member/approved countries. Proposals must address one or more of the following activities:

SCIENTIFIC CAPACITY DEVELOPMENT ACTIVITIES that promote the following approaches related to one or more of the six thematic areas of APN:

• Utilising and strengthening existing capacity, 
• Creating opportunities to use/instil capacity, 
• Developing new capacity through innovative approaches.

AWARENESS-RAISING AND DISSEMINATION activities through policy- and decision-making communities, civil society, and/or the general public.

SCIENCE-POLICY interfacing in the context of the priority topics.

CAPACITY DEVELOPMENT PARTNERSHIP ACTIVITIES that contribute to the capacity development components of the evolving global change arena, including the UNFCCC Paris Agreement, IPCC, IPBES, post-2015 Sustainable Development Goals, Sendai Framework for Disaster Risk Reduction, and the UN Decade of Ocean Science, and ongoing and new global change and sustainability research programmes.

Activities geared towards using SCIENCE COMMUNICATION to disseminate knowledge generated from projects, particularly to non-science audiences.

The William Bingham 2nd Scholarship for Adult Learners Fund supports Maine's nontraditional students pursuing higher education. Established in 2017 to honor philanthropist William Bingham, this scholarship alleviates financial burdens for adult learners attending accredited colleges, universities, or training programs. Eligible applicants must be Maine residents and meet specific criteria, such as being over 25 or working full-time. The scholarship emphasizes the importance of preparation and commitment to education, making it a valuable resource for those seeking to advance their skills and knowledge.

Marr Anderson Family Foundation

Founded in 2016, The Marr-Anderson Family Foundation is inspired to serve and strengthen families and their communities. John and Rebecca Marr have Maine roots as part of their heritage and have been long time residents of Falmouth, Maine. They believe in the importance of compassion, determination and encouragement. Their family foundation is a continuation of their philanthropic path to serve in the areas of health, education and catastrophic events. The foundation is a family collaboration, which includes daughters, Stephanie, Andrea and Jennifer.

The Marr-Anderson Family Foundation’s mission is to promote education, health and offer compassionate support during times of crisis. In support of their mission, the Marr-Anderson Family Foundation provides philanthropic support to public charitable organizations for the purpose of encouraging education and health. In addition, the Marr-Anderson Family Foundation offers encouragement for individuals to fulfill their dreams and provides philanthropic aid during difficult times when one’s dreams may be put on hold.

Marr-Anderson Family Foundation Grant

The Marr-Anderson Family Foundation provides philanthropic support to public charitable organizations for the purpose of encouraging education and health. The Marr-Anderson Family Foundation provides grants only to public charitable organizations that fall within Section 501(a)(1) or 501(a)(9) and that further these purposes.

The Marr-Anderson Family Foundation supports non-profit organizations that align with our mission to promote education, health and offer compassionate support during times of crisis. The foundation’s objective is to support organizations that further these efforts.

The National Forest Foundation's Matching Awards Program connects communities to forests by funding stewardship activities that promote engagement with National Forests and nearby public lands. This program aims to create lasting impacts, ensuring that all communities can benefit from the rich resources of these natural areas. By supporting various projects, the program fosters a deeper relationship between people and the environment, ultimately enhancing conservation efforts and community well-being.

The Maine Expansion Arts - Rural grant supports arts organizations and programs in rural Maine, focusing on accessibility to the arts for underserved communities. Established by the Maine Community Foundation, this grant prioritizes projects with annual budgets below $250,000. Eligible applicants include nonprofit organizations, municipalities, and public agencies. The initiative aims to strengthen local artistic traditions and foster community engagement, ensuring the arts are accessible to all, particularly in areas with limited resources.

The Haymarket People's Fund offers Urgent Response Grants of up to $5,000 for grassroots organizations in New England to address unforeseen crises or opportunities. These grants support both urban and rural social justice efforts and do not require 501(c)3 status. Priority is given to organizations led by people of color that incorporate anti-racism values. Applications are accepted on a rolling basis after a preliminary conversation with Haymarket staff.

The 25K for Kids Grant, offered by the Androscoggin Bank MainStreet Foundation, supports local non-profits in Maine that help at-risk youth access essential services such as food, shelter, and security. This annual grant of $25,000 is awarded to one organization after a competitive selection process involving presentations from finalists. The Foundation emphasizes direct service proposals that foster leadership, literacy, and mental health support, ensuring a positive impact on the community's vulnerable populations.

The Marvin R. and Pearl E. Patterson Family Fund Scholarship, offered by the Grand Haven Area Community Foundation, supports students aspiring to study graphic or fine arts, as well as those interested in environmental sciences. Open to high school graduates from the Tri-Cities area, this scholarship considers leadership, community involvement, and academic achievements, although financial need is not a requirement. Applicants must provide transcripts and relevant documents to qualify for this opportunity.

The Award for Teaching Excellence, presented by the Maine Education Association, recognizes outstanding educators who demonstrate exceptional teaching skills, advocacy, and community engagement. Recipients receive a $1,000 award and the chance to represent Maine at a national gala. Five winners will receive $10,000 each, with one selected for the prestigious NEA Member Benefits Award, receiving $25,000. This award celebrates diverse educators committed to excellence and equity in education.

Assistive Technology Grant -  Allison Keller Education Technology Program

Realizing the gains that many people with autism have achieved using the iPad, the Allison Keller Education Technology Program was created in honor of Flutie Foundation Board Member Kevin Lane Keller's daughter Allison. The goal of the program is to help fill the financial and technological gap for schools and 501(c)3 organizations that assist individuals with autism.Applications will be considered for any technology tools and/or training that improve learning outcomes or performance. Examples include but are not limited to:

• Tablets & Accessories
• Apps
• Smartboards
• Laptops
• Technology Training
• Science, Technology, Engineering, and Mathematics (STEM) educational activities & access to STEM studies

The Flutie Foundation is seeking innovative partners who are using technology to address real needs facing the autism community. One program per public school district is eligible to be awarded an Allison Keller Education Technology grant annually.

The Abelard Foundation, established in 1958, supports progressive social change projects located east of the Mississippi River. With an average grant size of $12,000, they prioritize new initiatives with budgets under $350,000. The foundation emphasizes community organizing, civil rights, and empowering marginalized groups. Eligible applicants must be associated with a nonprofit organization and demonstrate a commitment to local leadership and broader policy connections. The board meets biannually to decide on approximately 15 grants per year, focusing mainly on general support.

The Enbridge Community Grant aims to enhance the quality of life in North American communities through strategic donations and sponsorships. With funding ranging from $1,000 to $10,000, the grant supports organizations focused on safety, education, environmental stewardship, and Indigenous culture. Enbridge encourages early applications, with decisions typically made within eight weeks. The grant seeks to empower local initiatives that foster community strength, vibrancy, and sustainability.

About Northeast SARE

The Northeast Sustainable Agriculture Research and Education (SARE) Program offers grants and education to farmers, educators, service providers, researchers and others to address key issues affecting the sustainability of agriculture throughout our region.

The program serves Connecticut, Delaware, Massachusetts, Maryland, Maine, New Hampshire, New Jersey, New York, Pennsylvania, Rhode Island, Vermont, West Virginia, and Washington, D.C. The program is administered by Northeast SARE's host institution, the University of Vermont.

Farming Community Grant Program

The Northeast SARE Farming Community Grant applies social science research and education projects that strengthen farming and food systems at the community level.

These projects explore innovative approaches to improving the health and sustainability of agricultural communities in the Northeast. This program supports projects that are grounded in community partnerships and informed by the lived experiences of farmers. It encourages collaboration among farmers, service providers, researchers, and nonprofit organizations to co-create solutions that are responsive to local needs and scalable across the region.

This program encourages innovative solutions to challenges in farming and food systems in the Northeast USA, including but not limited to the areas of: Marketing and business; Crop production; Raising livestock; Aquaculture; Economic and social sustainability; Ecological knowledge; Projects related to climate and/or bioenergy work that provide direct or indirect benefits to farmers,ranchers, and private foresters; and more.

Technical Assistance Program

Applicants and grantees of the Farming Community Grant Program are eligible for Technical Assistance (TA) provided by Northeast SARE’s Technical Assistance Providers.

Funding: This grant is reimbursement based; you must spend money to receive the grant funds.

The Gridiron Veterans Scholarship, provided by the Bob Woodruff Foundation, offers essential financial support for military veterans and first responders. This initiative focuses on wellness, rehabilitation, and recovery programs, ensuring participants can access mental health services, physical therapy, and holistic resources. The foundation prioritizes those facing emotional and physical challenges, empowering them to overcome barriers and improve their quality of life through customized, evidence-based support.

The Asian Cultural Council's Individual Fellowship provides artists, scholars, and arts professionals from Asia and the United States with opportunities for self-directed cultural exchange and research in unfamiliar regions. This program supports activities such as interviews, workshops, and archival research, fostering cultural immersion and collaboration. With a funding limit of $35,000, the fellowship encourages innovative proposals that enhance creative perspectives and relationships among peers, while also ensuring strong eligibility criteria for applicants.

The Fields Pond Foundation Grant aims to support community-based nature and land conservation initiatives that enhance public access and awareness. Grants typically range from $500 to $25,000, with a focus on projects that involve local residents in conservation efforts. The foundation prioritizes trailmaking, land acquisition, and educational programs, encouraging collaboration among organizations. It seeks to empower communities to connect with their environment while ensuring ecological integrity.

The NRP Research Grant Program offers up to $50,000 for healthcare professionals to explore optimal neonatal resuscitation methods. It encourages innovative research addressing gaps in transitional physiology and effective teaching of resuscitation skills. Applications must focus on evidence-based practices and demonstrate potential for meaningful impact in delivery room care. Researchers from Canadian and US institutions are eligible, though applications primarily focused on quality improvement without a research emphasis will not be considered.

The Asian Cultural Council's New York Fellowship offers a transformative six-month program for artists, scholars, and arts professionals from Asia. Participants engage deeply with New York City's vibrant cultural landscape, attending performances, exhibitions, and workshops while building networks with local communities. This unique opportunity fosters peer-learning and individual artistic development, encouraging fellows to incorporate their experiences into their practices and contribute to their home cultures. The fellowship emphasizes exploration, exchange, and support, culminating in a rich cultural immersion.