Best Grants for 501(c)(3) in Mississippi

The Klingenstein Third Generation Foundation's 'Transformation of Mental Health Care Program' seeks innovative research into improving mental health care access for children and adolescents, particularly from under-resourced backgrounds. Applications are invited for studies that build on promising pilot work, focusing on scalable delivery models and technology use. Eligible applicants are academic researchers based in the U.S. who can demonstrate rigorous research capabilities. The foundation plans to award up to two grants of $100,000 each year for two years.

HCLTech Grant Edition II focuses on impactful climate action by investing $5 million over five years to support NGOs in the Americas. This initiative aims to enhance sustainable projects that align with the 17 Sustainable Development Goals (SDGs). With a history of significant contributions in India, HCLTech is committed to achieving net-zero emissions by 2040 and fostering innovative solutions to address pressing climate challenges. The grant encourages collaboration and aims to transform communities through effective climate action.

The Edward Payson and Bernice Piilani Irwin Scholarship honors Bernice Pi'ilani Irwin, a notable figure in Hawaiian journalism. Open to undergraduate and graduate students residing in Hawaii, the scholarship aims to support those pursuing careers in journalism or communications. Applicants must demonstrate financial need and maintain a minimum GPA of 2.75 while attending an accredited U.S. college or university. This scholarship is an excellent opportunity for aspiring journalists to follow in Bernice's footsteps.

The Dalsemer Interstitial Lung Disease Award, funded by the American Lung Association, provides $50,000 per year for two years to support junior investigators researching interstitial lung disease. This award aims to foster independence in early-career scientists while building on the Association's 120-year legacy of improving lung health through innovative research and advocacy efforts, ultimately enhancing the lives of those affected by lung disease.

The Hasting Innovation Award for Interstitial Lung Disease, offered by the American Lung Association, provides $75,000 annually for up to two years to support early-career researchers. This award targets investigators with proven excellence and a track record of accomplishment, aiming to advance lung disease science. Successful candidates must have held a K or R type award within the last three to five years, fostering innovation and discovery in lung health.

The Lung Cancer Discovery Award, offered by the American Lung Association, supports innovative research aimed at improving outcomes for lung cancer patients. With funding of $100,000 per year for up to two years, this award encourages groundbreaking projects that enhance diagnostic and therapeutic strategies, investigate genetic forms of lung cancer, and develop novel screening methods. The initiative is a vital step towards reducing lung cancer morbidity and mortality, ultimately improving patient care and saving lives.

The OAR Community Grant aims to enhance the quality of life for autistic individuals by funding community-led projects that address physical health and support services. Grants ranging from $1,000 to $15,000 are available for initiatives designed to produce practical tools and resources. Eligible applicants include family members, autistic individuals, and community organizations committed to improving the lives of those affected by autism. Projects should be innovative, publicly accessible, and focus on priority topics such as health systems and community services.

The American Epilepsy Society offers Predoctoral Research Fellowships to support students conducting epilepsy-related dissertation research under expert mentorship. Proposals in basic, translational, or clinical research are encouraged. Each fellowship provides up to $30,000 for stipend and travel to the AES Annual Meeting for one year, along with a one-year AES membership. The number of awards varies annually based on available funding.

The Beacon Scholarship for Rural America, sponsored by Carrot-Top Industries, Inc., offers $1,000 scholarships to support low-income students from rural areas pursuing higher education. Eligible applicants must be graduating high school seniors, current college students, or adult learners with a GPA of 3.0 or higher, and reside in a rural area. The scholarship aims to empower students by alleviating financial burdens as they enroll in accredited college programs.

The American Epilepsy Society offers Postdoctoral Research Fellowships to support trainees conducting research on epilepsy's causes, treatment, and consequences. These fellowships provide up to $49,000 for stipend and benefits, $1,000 for travel to the AES annual meeting, and complimentary membership. Proposals can be basic, translational, or clinical research, and the number of awards depends on available funding.

The American Epilepsy Society offers Research and Training Fellowships for Clinicians, providing up to $75,000 for one year to support clinical fellows or new faculty aiming to advance in epilepsy research. This fellowship encourages proposals across basic, translational, and clinical research. It also includes $1,000 for travel to the AES Annual Meeting, membership benefits, and complimentary registration, fostering collaboration and knowledge sharing in the epilepsy research community.

The Edna B. Collins Scholarship, offered by the Community Foundation of Central Wisconsin, supports graduating seniors from Wautoma pursuing a degree in business. With awards ranging from $500 to $40,000, this scholarship aims to help students achieve their educational goals. Selection is based on academic performance, financial need, and extracurricular involvement, encouraging a diverse range of applicants to apply for this valuable opportunity.

The SABIC Innovative Plastics Scholarship supports the children of employees at the Mt. Vernon, Indiana facility, providing financial aid for post-secondary education. Eligible students include graduating seniors from any U.S. high school who are dependents of active employees. Selection is based on academic performance, leadership, and community involvement. Applicants must also submit an essay detailing their goals and achievements, along with an official grade transcript. This scholarship fosters educational advancement for employee families.

The Laine - Casey Laine Armed Services Scholarship, established to honor Lieutenant Casey Laine Swakon, supports students from the Coastal Bend area who have participated in JROTC or are part of ROTC programs. Eligible candidates include high school seniors, current college students, and veterans. Applicants must maintain a minimum GPA of 2.5 and complete at least 12 credit hours per semester, ensuring they are well-prepared for their academic pursuits.

The American Epilepsy Society's Junior Investigator Research Awards support early-career researchers in epilepsy. The awards, offering up to $50,000 for one year, aim to enhance the ability of new investigators to secure longer-term funding from sources like the NIH. Proposals are encouraged across a range of epilepsy research, including basic, translational, and clinical studies, as well as health services research. This initiative also includes complimentary membership to the AES Annual Meeting.

The Inspired to Serve Scholarship Fund honors Seigo and Hisaye Kagawa, providing support for Kauai residents pursuing graduate studies in social justice, public service, education, or health. Established in 2016, it aims to assist students who demonstrate financial need, maintain a GPA of 3.0, and commit to full-time studies at colleges in Hawaii or the mainland. This initiative encourages future leaders to engage with their communities and contribute to meaningful change.

The AED Grant Program, run by the Hopey’s Heart Foundation, aims to enhance sports safety by providing life-saving AEDs to eligible schools and recreational centers. Although the program is currently closed, it will reopen for applications in April 2026. The Foundation focuses on preventing Sudden Cardiac Arrest among student athletes through education and medical equipment. Eligible organizations include 501(c)(3) entities and government bodies, ensuring broader access to vital resources for sports safety.

The Leukemia Exploration and Prevention Grant Program (LEAP) aims to advance cancer interception and prevention strategies for patients with RUNX1 familial platelet disorder. This initiative, supported by the American Cancer Society, focuses on understanding the mechanisms behind leukemia development and fostering innovative research leading to effective treatment options. Grants of up to $215,000 per year for four years are available, emphasizing the urgent need for targeted therapies in high-risk populations.

The Leukemia Exploration and Prevention Grant Program (LEAP) aims to advance cancer interception and prevention for patients with RUNX1 familial platelet disorder (RUNX1-FPD). This program supports interdisciplinary research teams investigating the mechanisms of leukemogenesis and innovative treatment strategies. With funding of up to $430,000 per year, LEAP encourages projects focused on both understanding clonal evolution and developing novel therapeutic approaches. The initiative seeks to bridge critical knowledge gaps and provide urgent interventions for high-risk populations.

The PATH Scholarship, established by the Ellucian Foundation in 2020, aims to support higher education institutions in assisting students facing financial hardships. With over $2.9 million awarded, it has benefited more than 3,100 students. Eligible institutions can receive grants ranging from $10,000 to $25,000, with individual awards up to $1,500. This initiative encourages public two-year colleges, particularly Minority Serving Institutions, to apply and adapt award criteria to meet the needs of their students.

The CART Fund Grant supports innovative Alzheimer’s Disease research projects in the U.S. with funding up to $500,000 for a two-year period. It invites full-time faculty from public and private institutions to submit Letters of Intent, emphasizing novel concepts that advance biomedical knowledge. Selected finalists will be invited to apply for standard grants. The initiative aims to foster groundbreaking research initiatives lacking extensive preliminary data, ensuring a focus on projects with transformative potential.

The NIH is seeking innovative computational approaches to enhance the curation of biomedical research assets at scale. This initiative aims to accelerate access to secure datasets and computational models, facilitating transformative discoveries in biomedical science. Key deadlines for applications range from January 2025 to January 2027, covering standard, renewal, and AIDS-related grants. Applicants are encouraged to submit Letters of Intent 30 days prior to application deadlines to ensure a streamlined review process.

The High-End Instrumentation (HEI) Grant Program, offered by the NIH, invites applications for purchasing or upgrading high-end, specialized instruments, with a minimum award of $750,001 and a maximum of $2,000,000. This program supports NIH investigators aiming to enhance their research capabilities through advanced technologies such as mass spectrometers and electron microscopes. Applications must be submitted by 5:00 pm local time of the applicant organization.

The Sherry Wagner-Henry Board Fellowship, initiated by the United States Institute for Theatre Technology (USITT), offers a unique opportunity for emerging leaders in the theatre and entertainment industry. This 12-18 month program connects Fellows with experienced board members to enhance their professional skills. Participants gain access to board resources, attend meetings, and receive support for conferences, all valued at approximately $3,000 to $3,500. Ideal for individuals with 2-5 years of experience, this Fellowship fosters growth and leadership in nonprofit governance.

This funding opportunity invites applications for pilot projects focused on understudied proteins linked to rare diseases. The goal is to generate preliminary data and tools related to these proteins, which belong to druggable families with known rare disease associations. By supporting innovative research, this initiative aims to facilitate the characterization of these proteins, ultimately contributing to advancements in understanding and treating rare diseases.

Community Collaboration Challenge

Applications for the 2026 Community Collaboration Challenge are now open! With support from the Leon Lowenstein Foundation, the Challenge provides $5,000 – $10,000 awards to communities and is designed to support collaboration that expands and pilots evidence-based K-12 student supports in the form of high-impact tutoring, mentoring, student success coaching, postsecondary transition coaching, and/or wraparound/integrated student supports.

The Igor Gorin Memorial Award, established in 1993 by the Community Foundation for Southern Arizona, honors the legacy of Igor Gorin by supporting aspiring vocalists. With $382,000 awarded to 49 young talents, this fund provides unrestricted financial assistance for coaching, travel, and auditions. The 2026 award offers up to $12,000, aimed at those overcoming financial barriers to pursue operatic careers, ensuring that exceptional vocalists can thrive in their artistic journeys.