Best Grants for Small Nonprofits in New Hampshire

The High-End Instrumentation (HEI) Grant Program, offered by the NIH, invites applications for purchasing or upgrading high-end, specialized instruments, with a minimum award of $750,001 and a maximum of $2,000,000. This program supports NIH investigators aiming to enhance their research capabilities through advanced technologies such as mass spectrometers and electron microscopes. Applications must be submitted by 5:00 pm local time of the applicant organization.

This funding opportunity invites applications for pilot projects focused on understudied proteins linked to rare diseases. The goal is to generate preliminary data and tools related to these proteins, which belong to druggable families with known rare disease associations. By supporting innovative research, this initiative aims to facilitate the characterization of these proteins, ultimately contributing to advancements in understanding and treating rare diseases.

GBA1 Parkinson's Disease Research Catalyst Program

The GBA1-PD Research Catalyst Program seeks to build a deeper, globally integrated understanding of GBA1-associated Parkinson’s disease by aligning efforts across geographies and maximizing the value of shared datasets and research assets. Funding will support hypothesis- driven projects with an emphasis on integrative, cross-cohort analyses and the systematic characterization and standardization of models to enable broad use by the research community.

Funding

Duration: 12 to 24 months

Award Amount: Up to $300,000. Requested support should be commensurate with work proposed.

These budgets include direct and indirect costs. For academic and for-profit institutions, no more than 15% or 10%, respectively, may go to indirect costs. 

The Domestic Violence Prevention grant aims to enhance access to forensic healthcare services for American Indian and Alaska Native victims of domestic violence and related issues. By fostering multidisciplinary partnerships, this initiative promotes trauma-informed care and improves victim support across IHS Areas. The focus is on developing comprehensive, culturally sensitive services that ensure timely interventions and coordinated responses to vulnerable populations, thereby enhancing overall victim well-being and safety.

The Alliant Credit Union Foundation, established in 2008, is dedicated to bridging the digital divide for underserved communities. By providing reliable broadband, digital literacy resources, and technology equipment, the foundation aims to promote economic empowerment and self-sufficiency. They support 501c3 organizations that share similar missions and emphasize the importance of financial literacy. Their initiatives include collaboration with community leaders and organizations to deliver essential resources where they are needed most.

The Caplan Foundation for Early Childhood provides grants to support innovative projects aimed at improving the welfare of young children in the U.S. The foundation focuses on early childhood welfare, education, and parenting education, promoting safe environments and effective teaching methods. Grants are awarded to projects with significant potential impact on children's lives, emphasizing national application and interest. Eligibility requires 501(c)(3) status, while ineligibility includes funding for foreign programs and capital equipment.

The AISES Sports and Technology Scholarship aims to empower Indigenous students pursuing degrees in STEM fields. Sponsored by the American Indian Science and Engineering Society, this scholarship supports American Indian, Alaska Native, Native Hawaiian, Pacific Islander, and First Nations students, ensuring they have the financial resources needed to excel. Eligible applicants must be full-time students in accredited programs and demonstrate tribal affiliation, contributing to a diverse future in technology and science.

Joseph G Markoly Foundation Inc

When Joseph Markoly originally established the foundation more than thirty years ago, its focus was on Alzheimer’s and heart disease support, funded through a number of the larger national disease-related organizations. Over time the focus has shifted to helping small to mid-size organizations in our local communities which support children and seniors in a variety of effective ways. 

Markoly Foundation was established in honor of Joseph G. Markoly, an entrepreneur and philanthropist who wanted to make a positive impact in people’s lives. Joseph’s family was affected directly by both Alzheimer’s and heart disease having lost a family member to each condition. For that reason, the foundation dedicates a majority of their resources to providing grants to organizations that focus on the treatment of each of these diseases. In addition, Markoly Foundation supports a variety of programs dedicated to helping children and seniors by providing services, supplies, programs and research in areas impacting these demographics.

Joseph G. Markoly Foundation Grant Support for Children’s Organizations

Children are the future of this world and the Markoly Foundation is proud to fund local programs dedicated to improving the lives of children and their families. From providing vision services for school kids to classes on parenting, we are proud to do our part to help fund critical community programs for families.

We are dedicated to providing funding for local nonprofit programs that improve the quality of life for all, but particularly for the children and elders in our community.

Manuel And Fillie Garcia Hispanic Scholarship

The Manuel & Fillie Garcia Hispanic Scholarship was established as a permanent fund of Taos Community Foundation in 2011.

The award is available to graduating seniors in Taos and western Colfax counties with preference to Hispanic students pursuing advancement of higher education. The scholarship is available to those applying to 4 year colleges and universities as well as 2 year vocational/trade schools.

The award amount will be determined at the time of committee review. This award is typically renewable for up to three years if a 2.5 GPA is maintained and all required paperwork is returned in accordance with the Scholarship Agreement.

Youth Service America

Youth Service America believes that youth, communities, and our democracy thrive when we all work together for the common good. YSA is a leading global nonprofit that activates young people, ages 5-25, to find their voice, take action, and acquire powerful civic and 21st Century skills as they solve problems facing their communities. YSA supports its activation campaigns with grants, training and resources, and recognition programs for young people and their adult champions. Youth-led projects use Awareness, Service, Advocacy, and Philanthropy (ASAP) strategies to create social and environmental change.

We Serve To Remember Grants

Projects that Engage 100 Youth Volunteers

YSA’s We Serve to Remember 9/11 Day of Service Grants are for organizations, schools, and youth changemakers ages 5-25 to lead service projects on or around September 11, 2026. Programming efforts should also honor and pay tribute to those who lost their lives on September 11, 2001, their families, and those who rose in service in response to that tragedy. (We suggest starting with eleven reflections about 9/11/01 and related ideas for service or service-learning projects.)

Grantees are required to engage at least 100 youth as volunteers in planning and implementing the service activities.

What are we looking for?

• Projects must be youth-led;
• Projects must include elements to honor and pay tribute to those who lost their lives on 9/11, their families, and those who rose in service in response;
• Projects must take place on or around September 11th National Day of Service and Remembrance (Friday, September 11, 2026) – between Friday, September 4 and Friday, September 18;
• Project organizers must make their best effort to recruit and engage youth volunteers who are not usually asked to serve;

Grantees are also required to provide evidence of volunteer participation and number of hours served. Approved documention includes sign in sheets, copies of pre-and-post-surveys, or reports from school attendance or volunteer management system. These documents must contain a unique identifier for each volunteer, such as the volunteer’s full first and last name, their full first name and last initial, or a volunteer/student ID number.

Reflecting on the spirit of togetherness that brought people together in the days, weeks, and months after September 11th, we are especially looking for ideas that bring together all members of the community.

The FY26 Vision Research Program's Investigator-Initiated Research Award (IIRA) offers funding for innovative research addressing eye injury and visual dysfunction due to military exposure. This award supports preclinical to early translational studies aligned with specific focus areas. Unique features include two funding levels and a Partnering Principal Investigator Option. Applications undergo rigorous peer review based on research rationale, strategy, and impact, with potential for sharing with the National Eye Institute for additional funding consideration.

The FY26 Vision Research Program Clinical Trial Award supports the swift execution of clinical trials aimed at improving treatments for service-connected eye injuries and visual dysfunction. This award emphasizes the need for regulatory compliance, including IND/IDE submissions, and requires documentation confirming the application's active status by March 1, 2027. Review criteria focus on clinical impact, research feasibility, recruitment strategies, and ethical considerations, ensuring relevance to military health.

The DoW Vision Research Program's FY26 Translational Research Award aims to accelerate the development of innovative drugs, devices, or clinical guidelines ready for clinical trials. It supports preclinical studies and pilot trials, ensuring alignment with specified VRP Focus Areas. Key features include a requirement for regulatory expertise in drug/device development and a unique Partnering Principal Investigator option. Review criteria focus on research rationale, strategy, feasibility, and impact, enhancing military health outcomes.

About NCCF

For more than 50 years, NCCF has been taking on tough problems to improve the quality-of-life in Northwest CT by supporting nonprofits that speak to the charitable passions of our generous donors.

NCCF is a Community Foundation, a tax-exempt public charity that enables donors to establish funds that support the work of local nonprofits through grants and provide scholarships to local students.

NCCF's Board and Staff champion the causes you care about with smart grant-making designed specifically to adapt over time and provide highly attentive, knowledgeable, and compassionate service that brings donors and organizations together to address community issues.

Scholarship Opportunities and Applications

Through the generosity of fundholders and donors, NCCF has awarded more than half a million dollars in scholarships to assist students in Northwest Connecticut with the cost of higher education.

Michele Farley Pittler Scholarship

• Academic Focus: Unspecified
• Award Average: $1,000

The Mae Casali Bonvicini Scholarship, offered by the Northwest Connecticut Community Foundation, supports Torrington High School graduating seniors aiming for higher education. With awards ranging from $400 to $1,500, this scholarship is designed to ease financial burdens for students who are U.S. citizens or permanent residents in the NCCF’s service area. For over 50 years, NCCF has dedicated itself to enhancing the quality of life in Northwest Connecticut through grants and scholarships.

The Edward W. Diskavich Scholarship, established by the Northwest Connecticut Community Foundation, honors the legacy of Edward W. Diskavich. It aims to support students from Oliver Wolcott Technical High School who are U.S. citizens or permanent residents in the service area. With awards ranging from $300 to $1,000, this scholarship helps alleviate the financial burden of higher education for deserving students, reflecting NCCF's commitment to enhancing community well-being through accessible educational opportunities.

The Bonita Kraft Occupational Therapy Doctoral Student Scholarship, valued at $5,000, supports doctoral candidates in occupational therapy focusing on mental health research. This scholarship honors Bonita Kraft, a dedicated advocate for integrating occupational therapy into mental health services. Eligible applicants must be enrolled in a doctoral program, have IRB approval, and conduct research addressing chronic mental health conditions in adults. The scholarship aims to enhance the visibility of occupational therapy within mental health treatment.

The AOTF Implementation Research Grant supports innovative research aimed at integrating evidence-based practices into occupational therapy. This grant encourages projects that directly involve stakeholders, particularly from underrepresented populations, to address health inequities. With funding options of up to $100,000 for two years or $50,000 for one year, the AOTF seeks to enhance the effectiveness of care through practical implementation strategies in diverse clinical settings.

The American Occupational Therapy Foundation's AOTF Intervention Research Grant Program supports innovative research in occupational therapy, providing up to $100,000 for projects that address health inequities and social justice. This initiative aims to generate preliminary data essential for larger studies, aligning with the profession's Vision 2025. By focusing on underrepresented populations, the program encourages inclusivity and ethical research practices, ensuring a diverse study population. This funding opportunity is crucial for advancing evidence-based practices in occupational therapy.

The Journalism & Media Grant aims to promote inclusive narratives and accurate media that engage communities in democratic processes. It supports U.S.-based nonprofit organizations focused on professional reporting, multimedia storytelling, and civic media. The grant addresses barriers to media participation and fosters innovation in journalism, providing essential infrastructure for a diverse media landscape. While unsolicited proposals are not accepted, organizations can share ideas through a Letter of Inquiry (LOI).

The American Journalism Project is dedicated to enhancing local news organizations by investing in their business capacities and providing personalized coaching. They prioritize diversity, equity, and inclusion, encouraging inquiries from organizations serving underrepresented communities. Their approach offers tailored support based on grantees' strategic challenges, fostering sustainable growth in revenue and programming. They seek grantees with strong public-service missions, independent 501(c)(3) status, and a commitment to transparency and accountability in their operations.

The Edna B. Collins Scholarship, offered by the Community Foundation of Central Wisconsin, supports graduating seniors from Wautoma pursuing a degree in business. With awards ranging from $500 to $40,000, this scholarship aims to help students achieve their educational goals. Selection is based on academic performance, financial need, and extracurricular involvement, encouraging a diverse range of applicants to apply for this valuable opportunity.

The Tommy Wells Foundation Grant supports youth aged 4-18 in music and hockey programs by providing financial assistance. As a 501(c)(3) nonprofit, the Foundation raises funds to honor Tommy Wells' legacy. Organizations in the greater Nashville, TN area are preferred for funding. The TWF encourages applicants to request funds for those who will benefit most, ensuring accountability by requiring confirmation of fund usage within a year.

The Arthritis National Research Foundation (ANRF) offers grants for research focused on Psoriatic Arthritis (PsA). With funding of up to $125,000 over two years, the ANRF encourages innovative projects that reveal the underlying mechanisms of PsA. Eligibility includes M.D. or Ph.D. qualifications and affiliation with a U.S. nonprofit research institution. Preference is given to senior post-doctoral researchers transitioning to independent status and new assistant professors. Applications without a Co-PI or those who have previously received ANRF funding will not be accepted.

The FY26 Breast Cancer Research Program (BCRP) Breakthrough Award Level 4 supports innovative research with the potential for significant breakthroughs in breast cancer. Applications must address key BCRP challenges or justify exceptions, focusing on impactful solutions. This program mandates clinical trials and requires participation from breast cancer consumer advocates. The funding supports single or partnered Principal Investigators, ensuring comprehensive submission processes to avoid administrative withdrawal.

The DoW Ovarian Cancer Academy Early-Career Investigator Award supports junior faculty in conducting innovative ovarian cancer research. Established in FY09, this unique virtual academy fosters mentorship, collaboration, and networking among Early-Career Investigators (ECIs) and their mentors. Participants engage in monthly webinars and annual workshops, enhancing their research skills while contributing to impactful studies in ovarian cancer. The program aims to cultivate a new generation of highly productive researchers in this critical field.

The Ovarian Cancer Clinical Trial Academy (OCCTA) supports Early-Career Investigators (ECIs) in clinical trial research aimed at effective ovarian cancer treatments. It provides essential mentoring, networking, and skill development needed for executing clinical trials. The FY26 funding will specifically support translational research and early-phase trials, requiring preliminary data and a commitment of at least 25% effort from the ECI. Mentorship is vital, with a focus on experienced clinical trialists guiding ECIs.