Best Grants for Capital Funding in New York

The Melanoma Established Investigator Award offers up to $125,000 annually for two years, aimed at established melanoma researchers or senior researchers transitioning into melanoma research. Eligible applicants include Associate Professors or higher, with both tenured and non-tenured faculty encouraged to apply. U.S. citizenship is not a requirement for this funding opportunity provided by the Melanoma Research Foundation.

The MRFBC Young Investigator Team Award supports innovative research in immuno-oncology for melanoma, offering up to $150,000 annually for two years. This funding targets U.S.-based researchers aiming to enhance clinical outcomes for melanoma patients or deepen the scientific understanding of immuno-oncology. The MRF collaborates with key institutions to address challenges in melanoma research, fostering partnerships that maximize research potential and impact.

The NIAID SBIR Phase II Clinical Trial Implementation Cooperative Agreement (U44) invites small businesses to submit applications for investigator-initiated clinical trials. This program particularly supports high-risk, hypothesis-driven studies that may involve non-routine interventions or unlicensed products. Letters of Intent are encouraged and due 30 days prior to the full proposal deadline. All applications must be submitted by 5:00 PM local time of the applicant organization.

The Great Lakes Fisheries Trust offers grants for ecological and biological research aimed at enhancing ecosystem health and sustainable fish populations. These grants support competitive fisheries research, focusing on resilience, sustainability, and stakeholder value. The next funding cycle will open with a request for proposals in late 2026 for the 2027 program year, promoting innovative research and capacity-building efforts within the fisheries sector.

The AHRF Discovery Grants support innovative research on hearing and balance disorders, offering up to $50,000 for one year. Targeting early-career investigators, these grants aim to generate preliminary data for larger funding applications. Special consideration is given to projects exploring Meniere's disease and sudden hearing loss. Grants cover direct research costs, excluding principal investigator salaries and indirect expenses. The initiative strives to fund promising studies that can advance our understanding of auditory and vestibular health.

The Friends Foundation for the Aging Grant supports innovative and impactful programs aimed at addressing the needs of older adults, particularly within underserved populations. This Quaker foundation prioritizes collaboration and sustainability in its funding efforts. Eligible applicants must be 501(c)(3) public charities focused on enhancing the quality of life for aging individuals. Grants are typically awarded for one year and target organizations that align with the foundation's mission and values.

The Syringe Service Program Grant, offered by The Comer Family Foundation, aims to enhance harm reduction initiatives by funding syringe access programs across the U.S. These programs provide sterile syringes, education, and support services to mitigate the risks associated with drug use, including HIV and hepatitis transmission. Priority is given to organizations in underserved areas and those led by marginalized communities. Grants are available for operational costs, program development, and staff training, with a focus on sustainability and local partnerships.

This project aims to enhance health outcomes for women living with HIV in the South by integrating HIV care with comprehensive women's health services through coordinated Clinic and Community Collaboratives. By funding organizations to implement targeted strategies such as culturally responsive services and learning collaboratives, the initiative seeks to improve access to essential health services, increase the number of women initiating rapid ART, and foster sustainable healthcare models that address the unique needs of this population.

Expanding Access to Middle-Wage Occupations

Request for Proposals

The New York City Workforce Funders Collaborative invites proposals for system and pathway models and policy and advocacy efforts that expand access to middle-wage occupations and upskilling opportunities for low-income New Yorkers. Proposals may be submitted by a single organization or a coalition of organizations working together with one organization as the lead.

 The New York City Workforce Funders Collaborative will award grants of up to $500,000 for projects that build the capacity of a New York City workforce development system to connect low-income New Yorkers to a middle-wage occupation or a group of occupations. The City’s workforce development systems include its public workforce agencies; the field of nonprofit organizations; the City University of New York (CUNY) system; the field of labor unions; industry partnership hubs; and New York City Public Schools.

Competitive submissions will:

• Strengthen or expand training pathways to middle-wage occupations;
• Strengthen or expand advancement models that help workers secure middle-wage positions; and/or
•  Address structural barriers to effective middle-wage pathways for low-income New Yorkers.

Expanding Access to Middle-Wage Occupations

Request for Proposals

The New York City Workforce Funders Collaborative invites proposals for system and pathway models and policy and advocacy efforts that expand access to middle-wage occupations and upskilling opportunities for low-income New Yorkers. Proposals may be submitted by a single organization or a coalition of organizations working together with one organization as the lead.

The collaborative will award grants of up to $200,000 for policy and advocacy efforts that:

• Increase the share of New York City’s middle-wage occupations;
• Expand access to middle-wage occupations for low-income New Yorkers, with a focus on reducing structural barriers to entry and advancement (including advocacy to increase public investments in pathways to middle-wage occupations);
• Develop and/or advance public policy solutions to support reskilling and upskilling for workers who have experienced labor market disruption; and/or 
• Implement concrete reforms to NYC’s workforce development systems that facilitate new or improved solutions to move more New Yorkers into middle-wage occupations.

The Colon Cancer Coalition offers the Get Your Rear in Gear Grants to support local programs aimed at improving colon cancer screening and awareness. Open year-round, applications are reviewed biannually in February and August. Grants fund initiatives that educate the public about colon cancer and alleviate the financial burden on patients. By applying, organizations commit to promoting local events that raise funds for these important community programs.

Napa Valley Community Foundation

There are more than 800 Community Foundations in the US, each devoted to a specific region. We operate independently, with a common goal in mind: to be a platform for local people who want to pay it forward. To deliver resources to effective charitable programs. And to make our communities stronger and more successful by doing these two things.

Among our peers, Napa Valley Community Foundation ranks first on several key measures of donor satisfaction and impact, according to a recent donor survey conducted by the Center for Effective Philanthropy. Our donors say that we deeply understand their interests, and deeply understand the needs of Napa Valley. That, in a nutshell, is our job.

Fruit of the Vine Scholarship

The Fruit of the Vine Scholarship Fund benefits graduating Napa County high school seniors and Napa Valley College transfer students who will find the cost of higher education a financial hardship. Consideration is given to applicants who are the first in their family to attend college or are employed (or have a parent or guardian who is employed) in the Napa County wine or grape industry. Recipients of the scholarship will receive funding for up to four years of undergraduate study.

The Mastercard Strive USA 2025 Innovation Fund aims to enhance the financial health of small businesses across the U.S. by providing up to $250,000 in grants to organizations developing innovative solutions. This initiative focuses on addressing challenges such as limited access to financial resources and vulnerability to economic shocks, ultimately fostering resilience and growth within the small business sector.

• Innovative: An approach that brings fresh thinking, tools, or models to homeownership in ways that challenge the status quo and demonstrate a disruptive, future-oriented vision with potential to inspire or shift broader field practice.
• Impactful: A solution with meaningful potential to expand homeownership through knowledge and action, featuring clear and measurable progress indicators that demonstrate capacity to shift trajectories for low- and moderate-income households.
• Bridge-Building: An initiative that effectively connects and unifies a wide range of stakeholders, fostering meaningful collaboration across sectors or perspectives. The strongest submissions will reflect strong community partnerships across the housing ecosystem.
• Durable: A sustainable pathway that addresses root causes of homeownership barriers rather than just symptoms, with compelling evidence of potential to elicit robust support from broad private, philanthropic, and public funding sources over time.

The OREF/MTF Biologics Research Grant encourages innovative research in biologics, focusing on reconstruction, bone regeneration, and transplantation, including stem cells. It is open to licensed U.S. orthopaedic surgeons and PhD researchers with faculty appointments. The grant seeks clinically relevant projects that demonstrate practical applications and multidisciplinary collaboration, promoting excellence in research. New investigators are especially encouraged to apply, ensuring a commitment to advancing orthopaedic science.

The Allergic Respiratory Diseases Award, supported by the American Lung Association and the American Academy of Allergy, Asthma & Immunology, aims to bolster research in allergic respiratory diseases. Designed for faculty in Clinical Allergy and Immunology at academic medical centers, this award offers $75,000 annually for up to two years. It seeks to empower researchers at pivotal points in their careers, enhancing understanding and treatment of these conditions while promoting lung health.

The Alliance for Innovation on Maternal Health (AIM) Capacity Program aims to enhance the capacity of state, territorial, and Tribal entities in the U.S. to implement and sustain AIM Patient Safety Bundles. By promoting evidence-based maternal safety practices, the program strives to improve the quality of maternity care, enhance maternal health outcomes, and significantly reduce preventable maternal mortality and severe morbidity.

The Ryan White HIV/AIDS Program Part D provides supplemental funding aimed at enhancing the infrastructure and capacity of organizations to deliver high-quality, family-centered HIV care services. This initiative focuses on two key areas: HIV Care Innovation and Infrastructure Development, ensuring improved access to essential services for women, infants, children, and youth affected by HIV.

The Ryan White HIV/AIDS Program Part B AIDS Drug Assistance Program Training and Technical Assistance aims to enhance the capacity of ADAPs. By providing essential tools and expert guidance, the program seeks to improve health outcomes for individuals living with HIV in an evolving healthcare landscape. This initiative is funded by the US HHS through the Health Resources & Services Administration, ensuring support and resources are effectively allocated to meet the needs of vulnerable populations.

The Cultural Competitive and Emerging Film Festival Grant aims to enhance arts and film initiatives that boost tourism and economic vitality in Suffolk County. By supporting community organizations focused on diversity and cultural participation, the grant encourages the development of innovative arts programs, partnerships, and public engagement. Applicants must demonstrate a commitment to accessible arts experiences and have a proven operational history, ensuring funds are directed towards impactful community-driven projects.

A funding opportunity designed to support food security, refugee services, licensed free healthcare clinics and community development organizations in the United States.

Turkey Distribution 2026

IRUSA facilitates annual Turkey Distributions in cities across the United States during Thanksgiving. IRUSA will procure and deliver turkeys to partners that will deliver them onto people in need. Along with turkeys, partner organizations may distribute other Thanksgiving goods to assist individuals and families who may not have access to these food items. The distribution may occur with regular food pantry distribution dates or as its own event. The goal of this event is to not only address food insecurity in local communities but to also embody the season of giving by bringing the holiday festivities to those who would otherwise not be able to enjoy a Thanksgiving meal in their homes.

A funding opportunity designed to support food security, refugee services, licensed free healthcare clinics and community development organizations in the United States.

Summer Food Service Program (SUN) program 2026

The Summer Food Service Program (SUN), created and funded by the United States Department of Agriculture (USDA), currently provides organizations with limited funding opportunities to purchase and provide meals to their local communities in the form of reimbursements. Starting in 2011, IRUSA began to supplement and support the USDA in this effort. SUN recipient, organizations are able to start a USDA-approved site, increase the capacity of their current USDA-approved site(s) or develop their role as the meal-providing sponsor to subgrantees. Grants are provided to further enable and encourage wider participation in this program as well as increase food access and support to food-insecure children throughout the summer months. 

Berkshire Taconic Community Foundation

Since 1987, we have strengthened communities through philanthropy and leadership. We channel generosity where it is needed, bringing together resources and passion to tackle our region’s most pressing issues and create lasting change.

The Region We Serve

Berkshire Taconic Community Foundation serves Berkshire, Columbia, northeast Dutchess and northwest Litchfield counties. This unique area where New York, Connecticut and Massachusetts meet contains 2,200 square miles of natural beauty and small-town charm that is home to nearly 230,000 people.

Fund for Columbia County: General Operating Support Grants

Introduction

Berkshire Taconic Community Foundation established the Fund for Columbia County (FCC) in 1998 to help strengthen communities and improve the quality of life for everyone in Columbia County. The fund serves as a resource for organizations that make life safer, healthier, and more equitable for all residents of the county.

Grants for General Operating Support

Through its General Operating Support Grants, FCC supports organizations that have a deep, lasting, and positive impact on the residents of Columbia County, with particular emphasis on low-income and underserved adults and children.

FCC’s primary focus areas include:

• Youth development
• Education
• Services for the elderly
• Health and social services
• Civic and community engagement through arts, culture, and education

These Grants provide flexible general operating support, which may include:

• Personnel and overhead costs
• Planning and implementation of programs
• Technology, equipment, or material costs
• Strategic planning, staff/board development, and/or succession planning
• Investments to increase organizational capacity
• Other annual operating expenses

The Jane Bruckel Early Career Investigator Award in Axial Spondyloarthritis, offered by the Spondylitis Association of America, aims to support MDs and PhDs at the Instructor or Assistant Professor level in the US and Canada. This annual $30,000 research grant promotes innovative research in ankylosing spondylitis and enhances patient care by encouraging emerging researchers to contribute to this important field.

The Cardiovascular & Pulmonary Research Grants aim to support impactful research that enhances cardiovascular and pulmonary health through physical therapy interventions. This grant emphasizes studies that assess patient characteristics, improve health outcomes, and address disparities. Research proposals must align with the 2023 APTA Research Agenda and prioritize clinical relevance, employing various investigative designs. The goal is to foster innovative approaches that significantly reduce cardiovascular disease risks and improve patient care in the U.S.

The Patrice Faye Cohen Memorial Scholarship Award supports high school women from Southern New Jersey who are pursuing college education with a focus on entrepreneurship. Established in memory of Patrice Faye Cohen, a successful business owner, this scholarship aims to empower women to achieve their entrepreneurial dreams. Eligible candidates must demonstrate a commitment to their studies and entrepreneurial aspirations, with financial support available for tuition and related expenses.

South Dakota Community Foundation

As a statewide community foundation, we work with donors, nonprofits and community leaders to strengthen philanthropy in South Dakota every day.

Scholarships

At South Dakota Community Foundation (SDCF), we proudly manage more than 350 scholarship funds in partnership with generous donors who are committed to supporting students. These scholarships offer countless opportunities to help ease the financial burden of continuing their education.

Spearfish Volunteer Firefighters' Association Scholarship

To provide financial support to individuals pursuing an education and training in the public safety industry.

The Spearfish Fire Department, established in the late 1880s as a volunteer organization, serves the northern Black Hills in western South Dakota. Its mission is to protect lives and property within the fire protection district and mutual aid area. Additionally, the department advocates for fire safety and provides fire safety education in local schools and the wider community.