Best Large Grants for Nonprofit Organizations in New York

The AOTF Implementation Research Grant supports innovative research aimed at integrating evidence-based practices into occupational therapy. This grant encourages projects that directly involve stakeholders, particularly from underrepresented populations, to address health inequities. With funding options of up to $100,000 for two years or $50,000 for one year, the AOTF seeks to enhance the effectiveness of care through practical implementation strategies in diverse clinical settings.

The NIH Research Software Engineer (RSE) Award aims to provide salary support for outstanding Research Software Engineers who play a vital role in creating and sharing biomedical, behavioral, or health-related software and tools. This opportunity encourages RSEs to enhance the development of algorithms and support training for prospective users. Applications are due by 5:00 PM local time, with optional Letters of Intent recommended 30 days prior to the proposal deadline.

The National MS Society offers annual Research Grants for investigator-initiated proposals addressing key research questions from the Pathways to MS Cures Roadmap. These grants support diverse studies, including clinical and nonclinical research aimed at stopping MS disease activity, restoring function, and preventing new cases. Eligible applicants must hold an M.D. or Ph.D. and demonstrate relevance to the Society's research priorities. This funding opportunity promotes collaboration and focuses on underserved MS populations.

The Spotlight Fund Grants aim to enhance racial equity in K-12 education by providing flexible funding to BIPOC educators. With grants ranging from $500 to $1,000 per educator, these funds are essential for sourcing tools and materials that support diverse student needs. As schools face budget cuts exacerbated by COVID-19, this initiative focuses on proven strategies that foster an inclusive learning environment for students of color, ensuring they have equal opportunities to thrive.

The Niskayuna Community Foundation Grant supports innovative projects addressing community needs, offering funding between $1,000 and $5,000 for a variety of fields, including arts, education, and health. Eligible applicants must be 501(c)(3) organizations or under fiscal sponsorship, serving Niskayuna residents. Grants for capital projects are also available, with matching grants encouraged. The foundation prioritizes non-discrimination in its grant-making process.

The Niskayuna Community Foundation Mini-Grants provide funding up to $2,000 for organizations that benefit the residents of Niskayuna, NY. Eligible projects can include arts, community development, conservation, health services, and recreation. The foundation supports nonprofit organizations under 501(c)(3) or those with fiscal sponsors. However, the grants do not cover individual projects, scholarships, research, or political activities, ensuring a focus on community enhancement and support.

The Bonita Kraft Occupational Therapy Doctoral Student Scholarship, valued at $5,000, supports doctoral candidates in occupational therapy focusing on mental health research. This scholarship honors Bonita Kraft, a dedicated advocate for integrating occupational therapy into mental health services. Eligible applicants must be enrolled in a doctoral program, have IRB approval, and conduct research addressing chronic mental health conditions in adults. The scholarship aims to enhance the visibility of occupational therapy within mental health treatment.

The Trans Justice Funding Project (TJFP) provides grants to grassroots trans-led organizations in the U.S. and territories, focusing on those with budgets under $250,000. TJFP supports initiatives that address varying needs within trans communities, including health, legal aid, and mutual aid projects. The organization prioritizes groups led by trans people of color and emphasizes the importance of centering marginalized voices in the fight for trans justice.

Every Battle Creek area resident shall have the resources to access post-secondary education and training.

Your dreams matter — and we want to help you achieve them. Whether you’re a graduating high school senior, an adult returning to school, or a graduate student pursuing advanced education, we’re here to support you by opening doors to opportunity.

Beyond tuition, many funds support total cost of attendance — books, fees, equipment, and in some cases childcare or transportation.

Checks are made payable to the educational institution indicated on the follow-up and mailed directly to the educational institution. Checks are typically mailed in early August.

In God We Trust, Mitchelle T. Savage Memorial Scholarship Fund

The In God We Trust, Mitchelle T. Savage Memorial Scholarship was established to provide educational opportunities beyond high school for Battle Creek area graduates or graduating seniors. Eligible recipients will be graduating seniors from Battle Creek area public and private schools who will be attending a college that is a member of the Council for Christian Colleges and Universities.

The Minnesota Ovarian Cancer Alliance (MOCA) is offering grants for research focused on the early detection of ovarian cancer. With funding amounts of either $50,000 or $100,000 available, these grants support projects aimed at enhancing prevention strategies. Eligible applicants include U.S.-based researchers outside of Minnesota, and the awards will be distributed in November 2025. This initiative aims to foster innovative approaches to combat ovarian cancer effectively.

Access Advocate for Clinical Research Participation

Objective:

This program will support implementation and evaluation of a Parkinson’s disease (PD) focused Access Advocate model designed to increase inclusive research participation. Funding will support Access Advocates at clinical sites to build practical, relationship based pathways to improving representative research enrollment and retention.

Funding Details:

• Duration: 24 months 
• Award Amount: $200,000 

The Michael J. Fox Foundation for Parkinson’s Research (MJFF) and its inclusive recruitment strategy has examined what barriers and motivators shape participation (e.g., FIRE-UP PD study3) as well as funded sites to pilot tactics that address those barriers (e.g., Black & African American Connections to Parkinson’s Disease study4). Now we aim to scale and validate approaches that show early promise by investing more deeply and measuring impact across settings.

This program will fund advocates at clinical sites to build practical, relationship-based pathways to improving representative research enrollment and retention. These support staff will help patients and care partners navigate health system complexity and everyday needs that often determine whether research participation is feasible. They will help address barriers such as transportation, caregiving responsibilities, language needs, and insurance and financial strains by connecting people to resources, coordinating logistics and providing consistent follow-up. These advocates also should discuss research participation opportunities with patients and connect them to recruiting studies.

The model is grounded in the idea that research participation is more feasible when (i) foundational practical needs are addressed first and (ii) raised by a trusted health care partner. By helping to reduce practical barriers, advocates are expected to increase screenings, enrollment conversion and retention across key trial milestones.

This program will test these hypotheses and further establish training, infrastructure needs and sustainability of such positions.

Program Goal

This program aims to:

• Support establishment of site-based Access Advocates to support potential participants and care partners across multiple active or planned PD studies.
• Evaluate needs and opportunities for onboarding and ongoing training for advocates in PD and clinical research fundamentals as well as site and local resources.
• Recommend repeatable workflows for identifying prospective participants, assessing barriers, connecting them to resources, coordinating logistics and supporting follow-up.
• Collect and report a core set of evaluation metrics across sites (reach, encounters, referrals, screened, enrolled, retained), including barrier tracking and resolution.
• Evaluate the impact of Access Advocates in recruiting and retaining underrepresented community individuals to/in Parkinson’s studies.
• Evaluate the impact of Access Advocates on “health system value” indicators (e.g., appointment adherence/show rates, medication access/adherence proxies) that could support funding sustainability from other sources.
• Establish a cross-site learning community that enables funded sites to share lessons, refine the Access Advocate model and inform broader adoption beyond the funding period.

At the Community Foundation for Muskegon County, we work with donors, grantees, and advisors to address key community issues.

Paul and Libby Kara Scholarship

This scholarship has been made possible by the generosity of Paul M. Kara, who established the Paul and Libby Kara Scholarship of the Community Foundation for Muskegon County. The Paul and Libby Kara Scholarship Fund helps graduating seniors or adult/returning students with significant financial need. It is designed to help students with the "last dollars" needed to continue their education. Paul and Libby believe that every student should be able to achieve their educational goals.

The Dr. Curtis Jones Leadership Award Scholarship, established by the Community Foundation of Central Georgia, honors the legacy of Dr. Curtis Jones, a distinguished educator and former Superintendent. This scholarship aims to support a graduating senior from Bibb County Public Schools who exemplifies leadership, scholarship, and citizenship. Awarded annually at $1,875, it is renewable for up to four years, encouraging students to achieve their academic goals while honoring Dr. Jones's commitment to education and community.

The ADDF-Harrington Scholar Program aims to transform academic discoveries into effective treatments for Alzheimer’s disease and related dementias. With funding of up to $600,000 annually, this program prioritizes innovative drug targets and supports research from hit-to-lead optimization to IND-enabling studies. Eligible applicants include academic investigators with a strong potential to advance meaningful therapeutics. The program emphasizes collaboration with industry experts, making it a significant opportunity for advancing dementia research.

The NIA Genetics of Alzheimer’s Disease Data Storage Site (NIAGADS) aims to create a secure, scalable cloud platform for genetic data related to Alzheimer’s disease. This initiative will enhance data accessibility, promote interoperability, and support rigorous research practices. By facilitating collaboration and providing robust analytical tools, the platform will maximize the scientific impact of AD/ADRD research, aligning with NIH goals for transparent and reproducible science, while addressing recommendations for broad access to high-value datasets.

The Emily Anne Dressler Memorial Scholarship, established in 1993 by the Saginaw Community Foundation, honors a remarkable young woman whose joyful spirit touched many lives. This scholarship aims to support high school seniors from Saginaw County pursuing their educational goals, particularly in Career and Technical Education (CTE) fields. With awards ranging from $500 to $4,000, it empowers students to achieve their dreams while tackling the growing demand for skilled trades in today's job market.

The Dr. Louis G. Economou Memorial Scholarship, established by the Saginaw Community Foundation, honors the legacy of Dr. Economou, a dedicated educator and community leader. This scholarship supports high school seniors in Saginaw County with a minimum GPA of 2.8 who demonstrate commitment to academics and extracurricular activities, particularly in varsity sports. Awards range from $500 to $4,000, aiming to assist students pursuing higher education or Career and Technical Education. The foundation emphasizes leadership, teamwork, and community service.

The Community Foundation’s scholarships are for Arkansas students pursuing education at two- or four-year colleges or universities, vocational schools or technical training programs. Each scholarship has its own eligibility criteria. Some scholarships are designated for graduates of a particular high school or those who plan to attend a particular college. Others are based on extracurricular activities or intended college majors.  

The Foundation has a scholarship portal with a quiz to help applicants determine scholarship eligibility. 

“Since 1976, the Community Foundation has partnered with individuals and organizations who want to support our state’s students in their pursuit of higher education,” said Heather Larkin, Community Foundation president and CEO. “These generous people provide the funding and determine the size and eligibility criteria of each scholarship, while we oversee the application and awarding process on their behalf.”  

Anne Pressly Scholarship

To memorialize the legacy of Anne Pressly and support women who plan to pursue a career in Journalism.

Residential Substance Abuse Treatment for State Prisoners (RSAT) Program

Overview

The Residential Substance Abuse Treatment (RSAT) Program is a formula grant program that enhances the capabilities of state, local, and tribal governments to provide residential substance use disorder (SUD) treatment to adult and juvenile populations during detention or incarceration, initiate or continue evidence-based SUD treatment in jails, prepare individuals for reintegration into the community, and assist them and their communities throughout the reentry process by delivering community-based treatment and other recovery aftercare services.

The RSAT Program encourages the establishment and maintenance of drug-free prisons and jails and development and implementation of specialized residential SUD treatment for individuals with co-occurring mental health and substance use disorders. The program also encourages the inclusion of medication-assisted treatment as part of any SUD treatment protocol.

The AMD Resident Research Grant aims to foster innovative research projects related to migraine, encouraging residents to explore diverse topics that are scientifically sound. Applicants, who must be enrolled in accredited training programs, can collaborate with preceptor investigators and receive support from their institutions. The grant is open to all residents without country restrictions, promoting advancements in migraine understanding and treatment.

The Harry Shwachman Clinical Investigator Award, offered by the Cystic Fibrosis Foundation, supports clinically trained physicians transitioning to independent researchers in cystic fibrosis. It provides up to $133,000 per year for three years to facilitate research tailored to individual interests. The funding covers personnel costs and supplies, promoting a strong mentorship during this critical stage of their academic careers.

The Path to a Cure (PTAC) - Postdoc-to-Faculty Transition Award by the Cystic Fibrosis Foundation supports postdoctoral fellows in advancing their research careers in cystic fibrosis. This program offers up to five years of funding, including 3 years for research training and 2 years for transitioning to an independent faculty position, with a maximum support of $110,000 per year. It aims to foster innovative research that develops new therapies for cystic fibrosis.

The Cystic Fibrosis Foundation offers the Path to a Cure (PTAC) Postdoctoral Research Fellowship Award to support innovative research training in cystic fibrosis (CF). Aimed at enhancing scientific knowledge and facilitating the transition to independent careers, this program funds projects targeting the development of new therapies for CFTR variants. Awards can reach up to $75,000 in the first year and $76,000 in the second year, fostering foundational research that could lead to breakthroughs in CF treatment.

The Ida Halpern Fellowship and Award, offered by the Society for Ethnomusicology, supports research on Native American music in the U.S. and Canada. Established scholars, recent Ph.D.s, and Ph.D. candidates are eligible, while previous awardees must wait three years to reapply. The fellowship includes a $4,000 grant and a $1,000 award for published research, with preference given to studies based on Dr. Halpern's Northwest Coast music collection.

The Pizza Hut Foundation is offering scholarships for students demonstrating financial need and community leadership. Eligible applicants must be U.S. residents aged 17-26, enrolled in accredited post-secondary education for Spring 2026, and maintain a minimum GPA of 2.5. Scholarship amounts range from $500 to $5,000, with distribution to be made in Spring 2026. The application period runs from July 8 to September 5, 2025, with notifications for recipients by November 17, 2025.

Scholarships and Awards

The National Federation of the Blind offers several scholarships and awards that honor blind individuals as well as teachers, professionals, entrepreneurs, and organizations whose work benefits the blind community.

Distinguished Educator of Blind Students Award

Honor a teacher who provides exemplary education, experiences, and opportunities for their blind students.

Every year, the Distinguished Educator of Blind Students Award recognizes an outstanding teacher of blind students. The education of blind children is one of the National Federation of the Blind's highest priorities. Please help us recognize dedicated and innovative teachers who provide quality education and meaningful experiences and opportunities for their blind students.

The Award

The Distinguished Educator of Blind Students Award is presented at the NFB National Convention. Honorees receive: 

• An expense-paid trip to attend the convention
• A check for $1,000
• A commemorative plaque
• A place on the agenda of the annual meeting of the National Organization of Parents of Blind Children
• The opportunity to attend seminars and workshops that address the current state of education of blind students, as well as a chance to meet and network with hundreds of blind individuals, teachers, parents, and other professionals in the field

The NCI Continuing Umbrella of Research Experiences (CURE) Non-Mentored Research Scientist Career Development Award (K22) aims to support postdoctoral fellows from underrepresented backgrounds in transitioning to tenure-track positions. This award provides essential funding for salary and research support for three years, enabling candidates to establish independent biomedical careers. Key deadlines for applications range from February 2025 to October 2027, ensuring ample opportunity for eligible researchers to secure funding for their career development.