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Best Large Grants for Nonprofit Organizations in New York

Find the perfect Large Grants for Nonprofit Organizations in New York on Instrumentl. 10,000+ Large Grants for Nonprofit Organizations in New York in the United States.

10,000+

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$2.80B

Total funding

$5K

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10,000+ grants
$2.80B total
$5K median

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10,274 Results based on applied filters

Siemens: Sponsorships

Siemens Medical Solutions USA, Inc.
Corporate
United States
Unspecified amount
Siemens Healthineers USA offers sponsorships to support healthcare initiatives across the U.S. They emphasize funding for healthcare organizations and related events, ensuring that requests comply with eligibility criteria. The company prioritizes diagnostic imaging, laboratory diagnostics, cardiology, and oncology. Applications must be submitted at least 45 days prior to the event, and funding is not available for sole sponsorships or certain excluded initiatives. For more information, visit Siemens Healthineers' official site.
Biomedical Imaging Patient Care & Services Cardiovascular Diseases & Systems +1 more

AGA-Bern Schwartz Family Fund Research Scholar Award in Pancreatic Cancer (Fund A)

American Gastroenterological Association
Association/Society
North America
US $300,000
The AGA-Bern Schwartz Family Fund Research Scholar Award in Pancreatic Cancer provides $100,000 annually for three years to early-career faculty focused on independent research in pancreatic cancer. This award aims to protect at least 50% of the recipient's time for research activities. Eligible applicants must hold an MD or PhD and be classified as early-career. The award encourages physician-scientists and underrepresented groups in biomedical research to apply, supporting innovative research that can lead to significant advancements in understanding pancreatic cancer.
Pancreatic Cancer

Integrated Specific Pathogen Free Research Models and Human New Approach Methodologies to Advance HIV/AIDS Research (U42 Clinical Trial Not Allowed)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
US $212,004 - US $2,725,311
This funding opportunity aims to advance HIV/AIDS research by implementing human new approach methodologies (NAMs) to reduce the reliance on specific pathogen free (SPF) animal models. It emphasizes the integration of NAMs-enabled frameworks for in vitro testing while supporting essential SPF colony resources. The initiative seeks to enhance research rigor and reproducibility through innovative strategies that prioritize human-relevant models, ultimately improving HIV research outcomes and facilitating collaborative development in the field.
HIV / AIDS

Limited Competition: Renewal of Existing NINDS-Supported Clinical Trial Cooperative Agreement Awards (U01 - Clinical Trials Required)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Unspecified amount
This funding opportunity invites renewal applications for existing NINDS-supported clinical trial cooperative agreements (U01) that require additional time and resources. The National Institute of Neurological Disorders and Stroke (NINDS) expects applicants to request only what is necessary for trial completion, without introducing new aims. Discussions with NINDS prior to submission are encouraged. Eligible applications must be renewals of previously approved cooperative agreements under specified NIH funding announcements.
Neuroscience Neurological Diseases & Disorders Stroke

John E. Thomasson Scholarship

The Community Foundation for a Greater Richmond
Private
United States
US $1,000

Our Story

Established over 50 years ago, our founders redefined local philanthropy, fostering connections around a shared sense of place and purpose. As Virginia's largest community foundation, we bring people together to pool resources, co-create solutions and align actions for impactful change in the Richmond region.

Scholarships are offered to students living in the Richmond region and other Virginia locations. Each scholarship was established by a generous individual, family, or organization with a desire to assist high school students, recent high school graduates, and adult learners to continue their education. 

John E. Thomasson Scholarship

The John E. Thomasson Scholarship Fund was established in 2001 to support postsecondary educational opportunities for youth of African American or other minority heritage in the Louisa County (Virginia) Public Schools or Fluvanna County (Virginia) Public Schools. Scholarships will be awarded on a competitive basis to students who have been admitted to an accredited two-year technical school, four-year Historically Black College or University or the school of their choice. Preference will be given to applicants planning to attend Virginia State University, Hampton University, Virginia Union University, or Norfolk State University.

Estimated Award Amount

  • (2) $1,000 
Education - Higher Education Vocational & Trade Education Career / College Preparation +2 more

Delaney L. Wykle Nursing Scholarship

Beckley Area Foundation
Private
United States
Unspecified amount
The Delaney L. Wykle Nursing Scholarship, managed by the Beckley Area Foundation, aims to support nursing students from Raleigh and Summers counties in West Virginia. Applicants must demonstrate financial need, possess a minimum 3.0 GPA, and be enrolled in an accredited four-year nursing program. This scholarship helps empower students to achieve their educational goals while enhancing community health services in Southern West Virginia.
Education - Higher Education Education - High School Academic Scholarship Programs +2 more

Store-Based Giving Program Grant

Ross Stores Foundation
Private
United States
US $300 - US $500
The Store-Based Giving Program by Ross Stores Foundation supports socioeconomically disadvantaged youth by providing gift cards for school or professional clothing. Organizations must be federal tax-exempt and serve at least 60% low-income youth. Eligible programs include academic achievement and life skills initiatives. Award amounts typically range from $300 to $500, depending on budget and mission alignment. Applications are not accepted from organizations that have received donations within the past 12 months.
Youth Services Financial Literacy Career / College Preparation +2 more

AIDS Research Center on Mental Health and HIV/AIDS (P30 Clinical Trial Optional) (362945)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The National Institute of Mental Health is inviting research applications for the AIDS Research Center program, which includes Developmental Centers and full Research Centers. This initiative aims to enhance interdisciplinary HIV/AIDS research through collaboration and innovative approaches across various scientific domains. The program emphasizes alignment with national strategies and encourages applications from teams skilled in fostering partnerships with diverse stakeholders. Although applications are currently not being solicited, this notice allows potential applicants time to prepare strong proposals.
HIV / AIDS

Improved Drug Susceptibility Testing (DST) for Mycobacteria

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The National Institute of Allergy and Infectious Diseases (NIAID) is funding research to enhance drug susceptibility testing (DST) for mycobacteria. This initiative aims to improve testing for tuberculosis (TB) and non-tuberculous mycobacterial (NTM) infections, which are on the rise. Current methods are slow and ineffective against drug-resistant strains, making rapid DSTs essential for effective treatment and reducing transmission rates. Innovative approaches, including rapid genotypic and phenotypic methods, will be supported to address these challenges.
Infectious & Parasitic Diseases Tuberculosis Drug-Resistant Bacteria

Broad Street Children's Foundation Grant

Broad Street Childrens Foundation
Private
United States
Unspecified amount

Who We Are

Broad Street Children's Foundation is committed to providing financial support to privately funded children's homes caring for the orphaned, abandoned and broken children right here in the United States.

Grant Seekers

Broad Street Children's Foundation supports self-sustaining children's homes across the United States that actively foster the development of strong, well-rounded children in their care.

Since the start of the Foundation, over $1,000,000.00 in grants have been donated to children's homes across the country. Additionally, through the Bill and Jackie Hazelgrove Scholarship Program, we have been able to assist a number of young people to continue their education and work towards a college or vocational degree.

Today, the Broad Street Children's Foundation is continuing the dream of it's original founders through the second generation. Equally as dedicated to changing the lives of children in need across America and striving to break the cycle of abuse and neglect for other children and their families.

Child Welfare Services Vocational & Trade Education Child Abuse & Neglect +2 more

Supplier Diversity Partnership Grant Opportunity

NY Small Business Funders Collective (SBFC)
Association/Society
Bronx County, New York, Kings County, New York +3 more
US $100,000 - US $250,000
The Supplier Diversity Partnership Grant Opportunity, led by the NY Small Business Funders Collective, aims to enhance supplier diversity for historically excluded entrepreneurs in NYC. This initiative focuses on innovative procurement solutions, fostering partnerships between buyers and sellers, and empowering Black, Latinx, AAPI, Indigenous, and women-owned businesses. The grant supports initiatives that address barriers in accessing contracts and promotes community-driven approaches to economic development, with funding ranging from $100,000 to $250,000.
Entrepreneurship Business Development Microfinance

Jacquelin Goldman Congressional Fellowship

American Psychological Foundation Inc
Private
United States
US $75,000 - US $90,000
The Jacquelin Goldman Congressional Fellowship offers developmental and clinical psychologists a unique opportunity to gain public policy experience while enhancing the application of psychological knowledge in government. Funded by the American Psychological Foundation, this fellowship supports one fellow annually with a stipend of $75,000 to $90,000, along with health insurance reimbursement and professional development funds. Applicants must demonstrate expertise in child psychology and policy issues, and have strong communication skills.
Psychology Children’s Mental Health Health Policy & Advocacy +1 more

Northern New York Community Foundation: Grants for Good

Northern New York Community Foundation
Private
Jefferson County, New York, Lewis County, New York +1 more
Unspecified amount
The Northern New York Community Foundation offers grants to support diverse programs addressing regional needs, including human services, health, arts, education, and environmental conservation. Eligible 501(c)(3) nonprofit organizations in Jefferson, Lewis, and St. Lawrence counties can apply. The Foundation evaluates proposals quarterly, with requests of $5,000 or less potentially approved at the committee level, while larger requests require Board review. Applicants will receive notification of award decisions after Board meetings.
Human & Social Services Health & Medicine Education +7 more

NANFA Conservation Research Grant

North American Native Fishes Association (NANFA)
Association/Society
North America
Up to US $2,000
The NANFA Conservation Research Grant, offered by the North American Native Fishes Association, supports research focused on conserving North America's indigenous fish species, particularly those that are threatened or endangered. With a maximum funding of $1,000 per proposal, this grant is open to academia, conservation groups, and independent researchers. Since 2001, NANFA has aimed to enhance knowledge about native fishes and promote their conservation through scientific research and community engagement.
Ichthyology (Fish) Fisheries Fish Conservation

Saltonstall Residency Program

Constance Saltonstall Foundation for the Arts
Private
Tompkins County, New York
Unspecified amount
The Saltonstall Foundation offers residency programs for writers and artists in New York, promoting diversity and inclusion. Eligible applicants must be at least 21 years old and reside full-time in New York State. The program spans 2, 3, or 4 weeks, with stipends available to support participants. There are no application fees, and additional financial assistance may be provided based on need. This initiative encourages creative individuals to engage in a nurturing environment.
Writing & Literature Film Visual Arts +3 more

TERF Research Grants

Thoroughbred Education and Research Foundation
Association/Society
United States
Unspecified amount
The Thoroughbred Education and Research Foundation (TERF) offers grants to support thoroughbred health, welfare, and education. Focused on enhancing equine research and safety in racing, TERF prioritizes funding for scholarships, educational programs, and veterinary medicine. Eligible applicants must be recognized 501(c)(3) organizations, with a commitment to transparency in reporting. This initiative aims to significantly impact the thoroughbred industry by fostering improved care and understanding of these horses, contributing to their overall welfare.
Mammalogy

Chapman Collection Study Grants

American Museum of Natural History (AMNH)
Private
New York County, New York
Up to US $2,000
The Chapman Collection Study Grants, administered by the American Museum of Natural History, provide financial support for predoctoral and recent postdoctoral researchers to conduct specimen-based ornithological research. Grants prioritize graduate students lacking other funding and cover travel and subsistence costs, encouraging projects longer than four days. Each grant is capped at $2,000 and aims to enhance research opportunities within the Museum's extensive collections, ensuring vital studies in avian systematics are conducted.
Ornithology

TERF Education Grants

Thoroughbred Education and Research Foundation
Association/Society
United States
Unspecified amount
The Thoroughbred Education and Research Foundation (TERF) offers grants to support education and research related to Thoroughbred horses. The foundation prioritizes funding for scholarships, educational programs, and equine research aimed at promoting thoroughbred health and welfare. Eligible applicants include qualified 501(c)(3) organizations, while those previously funded must submit reports before applying again. Notably, TERF does not provide funds for facilities caring for unwanted horses or cover overhead costs for grants.
Mammalogy

New Car Dealers of WNY Charitable Foundation Grant

NFADA CHARITABLE FOUNDATION (New Car Dealers of WNY Charitable Foundation)
Private
Allegany County, New York, Cattaraugus County, New York +15 more
Unspecified amount
The New Car Dealers of WNY Charitable Foundation Grant aims to enhance the well-being of children and families in Western New York. By providing financial support to not-for-profit organizations, the foundation seeks to increase their visibility and impact. Registered not-for-profit organizations can apply for restricted grants, with the board of trustees meeting twice a year to review applications. This initiative reflects the foundation's commitment to community enrichment and support.
Children’s Health & Pediatrics Youth Services Family Services +2 more

Moody’s Community Impact Grant Program

Moody’s Investors Service, Inc.
Corporate
Argentina, Brazil +21 more
Unspecified amount
The Moody's Community Impact Grant Program supports organizations with tax-exempt status to foster social and economic equality. Established by Moody's Foundation, it prioritizes initiatives that empower underestimated communities and entrepreneurs, driving innovation and ecological restoration. The foundation focuses on inclusive growth, providing resources for small businesses and community resilience. Eligible organizations must be registered charities under U.S. IRS guidelines, while ineligible entities include individuals and those promoting unlawful discrimination.
Business Development Entrepreneurship Habitat & Ecosystem Restoration

ASSP Foundation Academic Scholarships

American Society of Safety Professionals (ASSP) Foundation
Association/Society
United States
Unspecified amount
The ASSP Foundation Academic Scholarships provide vital financial support to students in environmental health and safety programs. With over $6 million awarded since 1990, the foundation aims to enhance career prospects through education and leadership development. In the 2024-2025 academic year, $215,000 was allocated to 117 recipients, fostering a sustainable talent pipeline in EHS. This initiative not only promotes the profession but also ensures a safer future for workers by encouraging new talent to enter the field.
Occupational Health & Safety Environmental Health Workforce Preparation & Job Readiness +1 more

NIAMS Clinical Trial Implementation Cooperative Agreement

National Institutes of Health
Federal Government
American Samoa, Guam +4 more
More than US $250,000
The National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) is inviting applications for the Clinical Trial Cooperative Agreement Program. This funding opportunity supports investigator-initiated, interventional clinical trials at various phases. Initial funding will facilitate the preparation needed to start trials, with successful milestones leading to further support. NIAMS emphasizes hypothesis-driven trials that promise significant clinical impact within its research mission.
Musculoskeletal Diseases Arthritis Skin Diseases & Dermatology

Demonstration Projects for Whole-Person Health Models for Women Living with HIV in the South

Dept. of Health & Human Services: Centers for Disease Control & Prevention
Federal Government
American Samoa, Guam +7 more
Unspecified amount
This project aims to enhance health outcomes for women living with HIV in the South by integrating HIV care with comprehensive women's health services through coordinated Clinic and Community Collaboratives. By funding organizations to implement targeted strategies such as culturally responsive services and learning collaboratives, the initiative seeks to improve access to essential health services, increase the number of women initiating rapid ART, and foster sustainable healthcare models that address the unique needs of this population.
HIV / AIDS

Native Public Health Resilience

Indian Health Service
Federal Government
United States
Unspecified amount
The Native Public Health Resilience (NPHR) program is a new funding opportunity aimed at supporting Tribes and Tribal Organizations in delivering essential public health services. Sponsored by the Indian Health Service, this initiative seeks to bolster public health infrastructure and resilience within tribal communities, ensuring they have the necessary resources to address health challenges effectively. Eligible applicants will receive financial assistance to enhance their public health capabilities and improve community health outcomes.
Epidemiology & Public Health Health Care Access & Delivery Native American Services +2 more

Exploratory Clinical Trial Grants in Arthritis and Musculoskeletal and Skin Diseases

National Institutes of Health
Federal Government
American Samoa, Guam +4 more
US $300,000 - US $600,000
The National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) is launching a funding opportunity for Exploratory Clinical Trials Grants. This program aims to support innovative clinical trials that enhance the understanding and treatment of arthritis and other musculoskeletal and skin conditions. Research proposals should focus on early-stage trials, including first-in-human studies, dose-finding, and biomarker evaluation. The initiative encourages the translation of promising laboratory findings into effective clinical practices, ultimately improving patient outcomes.
Musculoskeletal Diseases Skin Diseases & Dermatology Arthritis

Impact of Immunotherapies on CNS Outcomes in People with HIV: Potential Benefits, Challenges and Risks

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Up to US $2,000,000
The upcoming National Institute of Mental Health (NIMH) funding opportunity aims to explore the effects of HIV immunotherapies on central nervous system (CNS) outcomes. It seeks to identify mechanisms, benefits, and risks associated with these therapies, focusing on overcoming CNS-specific barriers. The initiative encourages collaborations to develop strategies for achieving sustained virologic remission and improving neurological outcomes for individuals with HIV, particularly targeting neurotoxicity and neuroinflammation.
HIV / AIDS

Delta Kappa Gamma Scholarship Fund

Stanislaus Community Foundation
Private
United States
US $3,000

Stanislaus Community Foundation provides scholarship opportunities for students in order to help them achieve their educational and career goals. We believe that by investing in our students, we are investing in a brighter future for Stanislaus. 

Delta Kappa Gamma Scholarship Fund

Applicants must be students currently enrolled in a teaching credential program, current student teachers, current teacher interns, students enrolled in a speech therapy program, or students enrolled in a school psychology program. Colleges considered: CSU Stanislaus, U.C. Merced, U.O.P., UMass Global, Teachers College of San Joaquin, Sacramento State University and CSU East Bay.

Award Amount:

  • $3,000
Education - Higher Education Psychology Teacher Development & Training +1 more

Large Grants for Nonprofit Organizations in New York Highlights

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Last updated: October 5, 2026. Next update: November 1, 2026.

Grant Insights : Large Grants for Nonprofit Organizations in New York

Grant Availability

How common are grants in this category?

Common — grants in this category appear regularly across funding sources.

300+ Large Grants for Nonprofit Organizations in New York grants for nonprofits in the United States, from private foundations to corporations seeking to fund grants for nonprofits.

100+ Large Grants for Nonprofit Organizations in New York over $25K in average grant size

100+ Large Grants for Nonprofit Organizations in New York over $50K in average grant size

38 Large Grants for Nonprofit Organizations in New York supporting general operating expenses

200+ Large Grants for Nonprofit Organizations in New York supporting programs / projects

2,000+ Grants on Instrumentl focused on Art & Culture

2,000+ Grants on Instrumentl focused on Human & Social Services

Grant Deadline Distribution

Over the past year, when are grant deadlines typically due for Large grants for Nonprofit Organizations in New York?

Most grants are due in the third quarter.

Q1
26.5%
Q2
21.7%
Q3
27.4%
Q4
24.4%

Typical Funding Amounts

What's the typical grant amount funded for Large Grants for Nonprofit Organizations in New York?

Grants are most commonly $52,500.

$300 $300 Min.
$52,500 $52.5 K Median
$870,598 $870.6 K Average
$40,331,313 $40.3 M Max.

Average Grant Size

What's the typical amount funded for New York?

Grants are most commonly $123,825.

$123,825

Total Number of Grants

What's the total number of grants in Large Grants for Nonprofit Organizations in New York year over year?

In 2024, funders in New York awarded a total of 270,645 grants.

2022 258,176

2023 259,835

2024 270,645

Top Grant Focus Areas

Among all the Large Grants for Nonprofit Organizations in New York given out in New York, the most popular focus areas that receive funding are Philanthropy, Voluntarism & Grantmaking Foundations, Education, and Human Services.

1. Philanthropy, Voluntarism & Grantmaking Foundations

2. Education

3. Human Services

Funding Over Time

How is funding for Large Grants for Nonprofit Organizations in New York changing over time?

Funding has increased by 16.44%.

2022 $28,202,880,598

2023 $28,659,853,906
1.62%

2024 $33,370,589,734
16.44%

New York Counties That Receive the Most Funding

How does grant funding vary by county?

New York County, Kings County, and Nassau County receive the most funding.

County Total Grant Funding in 2024
New York County $21,403,401,202
Kings County $2,517,718,693
Nassau County $2,484,899,697
Tompkins County $2,194,408,740
Rockland County $1,906,062,935