Best Large Grants for Nonprofit Organizations in New York

The IEN-WMAN Mini-Grant Program provides crucial financial support to Indigenous communities and grassroots organizations impacted by mining in the U.S. and Canada. With over $200,000 distributed annually in $4,000 grants, the program aims to address mining-related environmental and health issues. Priority is given to proposals that demonstrate a direct impact on affected communities, particularly Indigenous-led initiatives, ensuring that financial assistance is directed where it is most needed.

The Steven K. Dentel AEESP Award for Global Outreach recognizes faculty excellence in environmental engineering outreach. This annual award honors individuals who significantly contribute to global community health through education, research, and mentorship. Recipients receive a $500 cash award and a plaque. Nominations from students are welcomed, and past nominations can be modified within three years. This award aims to highlight sustained leadership and service in the environmental engineering field.

The National Fish and Wildlife Foundation (NFWF) invites proposals for the Bats for the Future Fund RFP to combat white-nose syndrome (WNS) affecting bat populations in North America. This initiative seeks to advance treatments, implement management strategies, and support research that enhances bat survival and recovery. A match of 50% of the grant amount is preferred, aimed at fostering innovative conservation efforts and collaboration among stakeholders to ensure the future of affected bat species.

The Perry L. McCarty AEESP Founders' Award, presented by the AEESP Foundation, honors outstanding contributions to environmental engineering education and research. It recognizes a professor's excellence in these fields, offering a plaque, a $1500 cash prize, and a $750 travel allotment for the awards ceremony. Nominations are accepted annually, with past submissions considered for three years. Careful adherence to nomination guidelines is essential for eligibility.

The National Institute on Deafness and Other Communication Disorders (NIDCD) and the National Institute of Biomedical Imaging and Bioengineering (NIBIB) are seeking innovative research applications for non-invasive imaging technologies to study the human olfactory system. This initiative emphasizes the need for advanced multimodal imaging techniques to enhance diagnostic capabilities for olfactory disorders, addressing challenges posed by the system's unique anatomical features. Collaboration among experts is encouraged to foster impactful research developments.

The NTSS Toshio Narahashi Neurotoxicology SS Trainee Conference Endowment Award offers a stipend of at least $250 to support deserving trainees in Neurotoxicology attending the SOT Annual Meeting. Selection is based on scientific merit and mentor support. This initiative, funded by the Toshio Narahashi Neurotoxicology Fellowship Award Fund, aims to enhance the professional development of trainees in toxicology.

The Excellence in Environmental Engineering and Science Education (E4) Award recognizes outstanding contributions by university faculty in environmental engineering education. Administered by AAEES and AEESP, this annual award includes a $1,000 monetary prize and $500 for travel to the E3 ceremony. Nominees should demonstrate significant impacts in curriculum development, student mentorship, and educational outcomes. Past nominations can be reconsidered for three years, encouraging ongoing recognition of excellence in environmental engineering education.

Interface Health Foundation

Interface Health Foundation is a non-profit, 501c3 tax-exempt organization driven by a collective vision of positive change. In healthcare industry policy, understanding the intricate dynamics of funding and its impact on public access, quality, and cost remains paramount. IHF is dedicated to advancing analysis and research into the crossroads of healthcare industry policy, structural frameworks and affordability.

At IHF, our mission is clear: to empower and support student-led research endeavors that shed light on critical healthcare policy and structural issues affecting the public. Through our initiatives, we seek to foster a deeper understanding of the complex dynamics shaping the healthcare landscape.

Interface Health Foundation: Research Grant

Healthcare administrative grant award opportunities are highly competitive and allow candidates to stand out as they enter the job market. Through this IHF grant award, you will get the opportunity to pull together research and content on topics that aren't fully studied or publicized. Depending on the grant topic, some grantees will also have access to a preceptor who is an executive leader in the healthcare field. The preceptor will serve as a valuable resource to the grantee during the development of the research paper and beyond.

An example of a research topic is the impact of legislated acute care nurse staffing levels on the following: nursing professional job satisfaction, the patient experience, and the standard nursing quality indicators as part of nursing Magnet status accreditation.

The FY26 Toxic Exposures Research Program (TERP) Clinical Trial Award supports clinical trials aimed at addressing health issues from military-related toxic exposures. This initiative encourages collaboration through a Partnering Principal Investigator Option, enhancing interdisciplinary research efforts. Projects range from early-phase trials to large-scale studies, focusing on innovative treatments and management strategies for affected populations. The goal is to expedite the translation of research findings into effective clinical applications.

The DoW Toxic Exposures Translational Research Award aims to foster translational research that bridges military-related toxic exposure studies and clinical applications. This program encourages innovative collaborations by allowing for a Partnering Principal Investigator Option, enhancing interdisciplinary partnerships. By integrating basic science with clinical insights, the initiative seeks to expedite the development of impactful health care products and interventions to address toxic exposures faced by military personnel.

The Emergency Mental Health Micro Grants, offered by the Indie Theater Fund NYC, provide $500 to NYC-based indie theater artists for mental health expenses such as therapy and medication. This initiative aims to reduce barriers to care, ensuring that artists receive the necessary support for their mental well-being. Priority is given to BIPOC, Trans/Non-Binary, disabled, and immigrant artists, fostering inclusivity within the arts community.

The Michael Hurewitz Scholarship, offered by The Community Foundation for the Greater Capital Region, supports high school seniors in the region who have a passion for journalism and demonstrate financial need. This scholarship aims to empower students by providing them the necessary financial assistance to pursue their educational goals in journalism, fostering the next generation of storytellers and communicators in our community.

American Headache Society

The American Headache Society (AHS) is a professional society of healthcare providers dedicated to the study and treatment of headache and face pain. The Mission of the AHS is to improve the lives of people impacted by migraine and other headache disorders. AHS advocates for those impacted by headache and the headache field, to meet our core objectives. AHS provides educational courses, scientific meetings, a journal, research support, career development opportunities, Special Interest Groups, advocacy training, and a professional community. The AHS strives to meet its objectives while fostering an inclusive sense of belonging and community.

Headache & Migraine Competitive Grant Program

The Headache & Migraine Competitive Grant Program stands at the forefront of advancing headache medicine by funding groundbreaking quality improvement initiatives. This highly competitive grant program, offered through the collaboration between the American Headache Society and Pfizer, supports projects that have the potential to reshape the field by creating widely applicable tools and driving measurable improvements in patient care. 

Migraine & Women's Health

Migraine is a prevalent and debilitating neurological disease that disproportionately affects women, impacting quality of life, productivity, and overall health. Recognizing the need for innovative solutions and enhanced care, Pfizer and the American Headache Society (AHS) are collaborating to offer a new grant opportunity inviting proposals for collaborative quality improvement and research projects focused on migraine and women's health.

The Graduate Education Fund offers the South Australia Defence, Space & Cyber Scholarship for scholars from the USA and South Australia. This scholarship supports PhD and Post-Doctoral research in Defence, Space, and Cyber Security, ensuring candidates have affiliations with educational institutions. Awarded funds, up to US $40,000, can cover tuition, travel, and living expenses. Applications are due in March for USA to Australia and September for Australia to USA, promoting collaboration in research between the two nations.

The Reel Change Film Fund is a five-year initiative aimed at supporting underrepresented film composers in the industry. It provides grants averaging $20,000 to assist US-based projects in production or post-production. Created by Christophe Beck and SESAC, this fund addresses the lack of diversity in film scoring, promoting inclusivity for diverse composers. Through mentorship and financial support, it seeks to elevate the careers of talented individuals from various backgrounds, enhancing the overall landscape of film music.

The Juan Diego Guadiana Legacy Foundation Scholarship supports students from Las Cruces High School or Doña Ana County, especially those affected by cancer treatment or pursuing health-related fields. This scholarship is open to various backgrounds, including BiPOC and LGBTQIA+ communities. The foundation aims to empower students at different educational stages, ensuring they have the resources necessary to thrive in their academic and professional journeys.

The Huether/Gillan Scholarship, established by the Niskayuna Community Foundation, supports community-minded students from Niskayuna or its school district. This need-based scholarship aims to assist those pursuing higher education while emphasizing academic achievement and community service. Mr. Huether initiated this scholarship in honor of his parents, promoting values of dignity, diversity, impact, inclusion, innovation, and integrity. Interested applicants should contact Mr. Vince Bianchi for further details.

The Manhattan Arts Grants: UMEZ Arts Engagement program supports Upper Manhattan artists and arts organizations in accessing funds to enhance cultural presentations. Managed by the Lower Manhattan Cultural Council, this initiative fosters community engagement through diverse art projects, promoting equity and accessibility in the arts. Since its inception in 1983, it has bolstered the cultural vibrancy of Manhattan, providing vital resources for artistic expression and collaboration within the community.

The Manhattan Arts Grants: Creative Learning, managed by the Lower Manhattan Cultural Council, supports local artists and organizations in providing community-based arts education, particularly for older adults. Established in 1983, this program enhances public spaces through artistic engagement and offers crucial funding to those unable to access city or state arts funding directly. With backing from various cultural institutions, it fosters creativity and resilience within Manhattan's diverse communities.

The UMEZ Arts Engagement Grant supports diverse arts initiatives in Upper Manhattan, inviting proposals from local artists and nonprofit organizations. This program aims to enhance cultural presentations and community engagement through publicly accessible projects. Eligible applicants include 501(c)(3) nonprofits and individual artists, all of whom must attend an information session before applying. Projects should promote public access to the arts and take place in Upper Manhattan between January 1 and December 31, 2025.

The Manhattan Arts Grants: Creative Engagement, offered by the Lower Manhattan Cultural Council (LMCC), supports artists and community-focused organizations in accessing public funds to present rich arts activities. Since 1983, these grants have been vital in fostering cultural vibrancy across Manhattan. With funding from the NYC Department of Cultural Affairs and other partners, LMCC helps artists connect with communities from Inwood to The Battery, enhancing public spaces through various artistic disciplines.

The Care Camps Grant supports children with cancer by funding medically supervised oncology camps that provide joy, hope, and healing through outdoor experiences. With the mission to foster a sense of community and shared healing, Care Camps Foundation aims to serve every child and family affected by pediatric cancer in the US and Canada. By collaborating with donors and volunteers, the foundation ensures that each contribution maximizes benefits for the families in need.

The Aim High Grant Program, funded by the New York Life Foundation, offers 15 two-year grants of $100,000 each to support out-of-school time programs that assist middle school students in their transition to high school. This initiative addresses chronic absenteeism and promotes educational attainment in low-income communities, enhancing the cognitive, social, and emotional development of youth. By fostering skills necessary for academic success, the program aims to create brighter futures for participants.

Spencer Educational Foundation Inc

The Spencer Educational Foundation was founded by the Rims Atlanta Chapter in 1979. To this day, Spencer remains the premier organization funding the education of tomorrow's risk management and insurance leaders.

The Spencer Educational Foundation: awards merit-based scholarships and grants to university students pursuing careers in risk management, insurance, and/or actuarial science; provides grants that create experiential learning opportunities both on and off campus; funds the development of risk management and insurance curricula in colleges and universities; supports Risk Managers by creating internship opportunities within the risk management function of their companies; and operates across the United States and Canada. 

Spencer Educational Foundation: General Grants

Spencer’s goal to help build a talent pipeline of Risk Management and Insurance professionals is achieved in part by our collaboration with Risk Management and Insurance educators across the United States and Canada. Since 2010, Spencer has awarded over $4.5 million in General Grants to support over 225 student-centered experiential learning initiatives at universities and RMI non-profit orgs.

Spencer's General Grants Program supports student-centered initiatives that (1) provide experiential learning opportunities for Risk Management & Insurance students and (2) attract new talent to risk and insurance careers. 

Rails-to-Trails Conservancy (RTC) Trail Grants

RTC’s Trail Grants are building strong foundations in communities for equitable trail network development and activation—investing in transformative projects and programs that create more access to trails for more people across the country.  

Our grants support organizations at all levels—from local and national nonprofits to public agencies—with a focus on community-based leadership, engagement and long-term impact.  

Since 2008, RTC has provided over $3.7 million in grant funding to more than 280 organizations seeking to create, connect and maintain the nation’s trails, building vibrant trail networks that connect neighborhoods and regions, and make it possible for America to walk, bike and be active outside.

Literary Arts Project Grants

As part of its Literary Arts Initiative, South Arts is pleased to announce Literary Arts Project Grants supporting literary arts organizations and small presses that focus on contemporary literary arts.

These grants advance South Arts’ commitment to amplifying the literary traditions and artistic practices of the American South by directly supporting the development, production, and public engagement of high-quality literary projects.

Literary Arts Project Grants support projects in poetry, fiction, creative or literary nonfiction, young readers’ literature, and drama (scriptwriting). Projects must demonstrate artistic excellence, editorial rigor, and meaningful public or community impact.

Award Amount

South Arts will award up to $5,000 per project to eligible literary arts organizations and small presses.

The Lam Research Core Values Scholarship, offered by the East Bay Community Foundation, supports high school seniors from specific districts in California and Oregon. Recipients are awarded $10,000 over four years, promoting educational success. Eligible students must exemplify Lam's Core Values, maintain a GPA of 2.7 or higher, and plan to attend a college or technical school. This scholarship aims to empower diverse youth in their educational pursuits and foster community development.