Best Grants for 501(c)(3) in North Carolina

Mission: To continually improve the Marion Area community through philanthropy, leadership and civic engagement. Kannan Family ScholarshipThe Kannan Family Scholarship is open to students from any high school in Marion County, with preference to seniors or graduates of Pleasant High School where the Kannan’s children attended. Their scholarship supports students pursuing a career in a STEM field – science, technology, engineering, or mathematics – or health care and special consideration will be given to those with demonstrated financial need.

The Pediatric Cancer Research Foundation (PCRF) offers the Emerging Investigator Fellowship Grant to support post-doctoral fellowships and clinical investigator training for promising pediatric cancer researchers. This grant aims to accelerate advancements in childhood cancer treatment by funding innovative research ideas. Applicants must have completed a minimum of two years in their fellowship or be within two years of their junior faculty role. This initiative fosters the next generation of researchers dedicated to combating childhood cancer.

A Little HOPE, Inc. is a charitable foundation that provides grants to organizations offering bereavement support services and grief counseling for children and young adults who have lost a loved one. The grant amounts vary based on project scope and budget. Applications are by invitation only, sent out each October, and interested organizations should submit an email with necessary details for consideration.

The Brothers Helping Brothers initiative aims to provide essential equipment to small fire departments and EMS organizations in the U.S. Established in 2014, the program offers grants to eligible agencies serving communities with populations under 10,000. With a focus on tools like wireless backup cameras, the organization strives to enhance safety and operational efficiency for first responders. Through community support, they have raised significant funds to assist in this critical mission.

Tyson Foods Community Giving Grants support initiatives that enhance the quality of life for communities and their members. With a focus on scaling existing effective programs, these grants are aimed at organizations that operate in underserved areas. Eligible nonprofits must have a 501(c)(3) status and local Tyson plant support. Applications are accepted annually, with priority given to projects addressing systemic community issues. Notable past support includes a $25,000 grant to the Arkansas Foodbank Mobile Pantry Initiative.

The Ittleson Foundation Environmental Program Grants support innovative projects that enhance environmental activism through education and grassroots efforts. In 2025, grants will focus on initiatives that strengthen environmental movements and engage new constituencies, particularly in environmental equity. The Foundation has provided resources since 1932 to improve public policy and community welfare, alternating its grantmaking focus annually between mental health and environmental initiatives.

Brothers Helping Brothers is a 501c3 non-profit organization dedicated to providing essential tools and equipment to small and rural fire departments. Founded in 2014 after a tragic loss, the organization has raised over $20,000 to support fire services. They grant financial assistance to eligible fire and EMS organizations across the U.S. with a focus on enhancing safety and operational capability. Their mission continues to grow as they research and address the pressing needs of emergency services.

The Edward Payson and Bernice Piilani Irwin Scholarship honors Bernice Pi'ilani Irwin, a notable figure in Hawaiian journalism. Open to undergraduate and graduate students residing in Hawaii, the scholarship aims to support those pursuing careers in journalism or communications. Applicants must demonstrate financial need and maintain a minimum GPA of 2.75 while attending an accredited U.S. college or university. This scholarship is an excellent opportunity for aspiring journalists to follow in Bernice's footsteps.

The Undiagnosed Diseases Network (UDN) aims to enhance diagnostic excellence through multiple clinical Networks of Diagnostic Excellence (NODEs). These NODEs will operate as regional networks, leveraging partnerships with various healthcare facilities to provide participant-centered evaluations for complex conditions. They will also engage in research and training to improve diagnostic tools and strategies. This initiative encourages collaboration and aims to improve the overall experience and access for participants in need of specialized care.

The MultiState Conservation Grant Program provides vital funding for wildlife and sport fish restoration projects, as well as initiatives aimed at recruitment, retention, and reactivation (R3) of outdoor enthusiasts. These grants address priority needs identified by the Association of Fish and Wildlife Agencies, supporting collaborative efforts among states to enhance conservation efforts. Eligible projects may include research, education, and public outreach, promoting sustainable use of natural resources and fostering community engagement in conservation.

NEXT for AUTISM's grants program empowers autistic adults by funding innovative initiatives across work, home, social engagement, and health & well-being. With over 380 funded projects nationwide, the program supports 501(c)(3) organizations in the U.S. First-time grantees can apply for up to $10,000, while returning grantees may request up to $25,000. The program emphasizes community-based solutions and aims to enhance the quality of life for autistic individuals.

The NC Sheriffs Association Undergraduate Criminal Justice Scholarship provides $2,000 annually to North Carolina residents pursuing a degree in criminal justice. Eligible students must be enrolled in a minimum of 12 credit hours and express interest in law enforcement careers. Recipients are prioritized based on their familial connections to law enforcement. This scholarship is administered by the North Carolina State Education Assistance Authority for UNC System students and by NC Independent Colleges and Universities for private institutions.

The Beacon Scholarship for Rural America, sponsored by Carrot-Top Industries, Inc., offers $1,000 scholarships to support low-income students from rural areas pursuing higher education. Eligible applicants must be graduating high school seniors, current college students, or adult learners with a GPA of 3.0 or higher, and reside in a rural area. The scholarship aims to empower students by alleviating financial burdens as they enroll in accredited college programs.

The Inspired to Serve Scholarship Fund honors Seigo and Hisaye Kagawa, providing support for Kauai residents pursuing graduate studies in social justice, public service, education, or health. Established in 2016, it aims to assist students who demonstrate financial need, maintain a GPA of 3.0, and commit to full-time studies at colleges in Hawaii or the mainland. This initiative encourages future leaders to engage with their communities and contribute to meaningful change.

The Combined Pilot Research Grants from the Plastic Surgery Foundation and the American Society for Peripheral Nerve support innovative research in peripheral nerve surgery. Aiming to enhance scientific knowledge and clinical practices, these grants fund preliminary projects with a maximum of $15,000 for one year. Eligible applicants include those with doctoral degrees or those in relevant clinical positions, encouraging new collaborations and research initiatives to advance the field.

The Community Foundation of Western Massachusetts administers over 160 scholarships. Some of the funds help students from a particular school or area; others provide financial assistance to those pursuing a specific field of study; still others assist students that are most in need. Students who apply to the Scholarship program may be eligible for many of these funds. 

Scholarships are provided for one academic year and are not automatically renewed each year. You can reapply to our program every year you are going to attend college, and the application you submit that year will be considered for all scholarships for which you are eligible.

Edward A. and Shirley B. Livi Scholarship Fund

To support residents of Franklin, Hampden and Hampshire Counties who are pursuing fine or performing arts beyond their college freshman year.

Additional Guidelines

• Students can receive up to $3,000 in scholarships from the Community Foundation.
• Scholarship awards could impact the financial aid offered by a college, and students are advised to check with their college financial aid offices about this.
• Scholarships may be used to offset tuition, fees, room and board, and other items included as part of the cost for attending the institution. Some part and/or all the award could be considered taxable income. It is advisable students check with the college or tax accountant regarding this matter.

The Fred and Betty Worsh Scholarship Fund, managed by the North Carolina Community Foundation, offers financial support to residents of New Hanover and Brunswick Counties who are U.S. citizens attending accredited four-year colleges or universities. Scholarships are available to undergraduates, graduates, and adult re-entry students, and may be renewed annually based on academic performance and financial need. Applications open on December 16, 2025, and close on March 3, 2026.

Mesothelioma Applied Research Foundation Inc

The Mesothelioma Applied Research Foundation is the only nonprofit charity organization dedicated to ending mesothelioma, and the suffering caused by this cancer, by:

• funding research to improve treatment options;
• providing treatment support and education for patients and their families;
• and advocating for federal funding of research.

The mission of the Mesothelioma Applied Research Foundation spans across four distinct areas: through research, education, support, and advocacy the Foundation seeks to eradicate the vicious effects of mesothelioma. Led by the Board of Directors, our team works collaboratively to develop and administer our programs, and to fundraise to pay for those programs (the Foundation is funded by private individual and corporate contributions only — it does not receive any government funding).

Bret A. Rosenthal Patient Assistance Fund

Patients diagnosed with cancer at a younger age often face greater financial burdens. This is a time in a patient’s life when they are raising a family, starting a career, or have not accumulated savings. For patients 49 and under, the Foundation administers the Bret A. Rosenthal Patient Assistance Fund grant program. This program is made possible by the generosity of the Rosenthal family.

The Elizabeth City Jaycees Scholarship Endowment offers financial assistance to graduating seniors from high schools in Camden, Chowan, Gates, Pasquotank, and Perquimans Counties. Eligible students must enroll full-time in a four-year accredited institution or specific community colleges. Applicants should demonstrate a GPA of 3.0 or above, financial need, and a commitment to community service. This scholarship aims to support students in achieving their educational goals while contributing to their communities.

The Minnesota Ovarian Cancer Alliance (MOCA) is offering grants for research focused on the early detection of ovarian cancer. With funding amounts of either $50,000 or $100,000 available, these grants support projects aimed at enhancing prevention strategies. Eligible applicants include U.S.-based researchers outside of Minnesota, and the awards will be distributed in November 2025. This initiative aims to foster innovative approaches to combat ovarian cancer effectively.

The Bar Success Intervention Grant Program, funded by AccessLex Institute, aims to enhance bar exam passage rates for at-risk law students and graduates. With grants ranging from $150,000 to $300,000 for programs lasting 12 to 24 months, the initiative seeks data-driven solutions that are scalable and replicable. Eligible applicants include U.S. nonprofit organizations and law schools. Programs should feature clear goals, measurable objectives, and a robust evaluation plan to ensure effectiveness and sustainability.

The Exploratory Grant Award aims to enhance workforce diversity in basic cancer research by supporting junior and Early Stage Investigators from underrepresented groups in the biomedical and social sciences. This initiative provides essential funding to bridge the gap for researchers completing their training, ensuring they have the resources needed to develop larger grant applications. Applications are due by 5:00 PM local time of the applicant organization, emphasizing the importance of timely submissions.

The Spotlight Fund Grants aim to enhance racial equity in K-12 education by providing flexible funding to BIPOC educators. With grants ranging from $500 to $1,000 per educator, these funds are essential for sourcing tools and materials that support diverse student needs. As schools face budget cuts exacerbated by COVID-19, this initiative focuses on proven strategies that foster an inclusive learning environment for students of color, ensuring they have equal opportunities to thrive.

The NIH Research Software Engineer (RSE) Award aims to provide salary support for outstanding Research Software Engineers who play a vital role in creating and sharing biomedical, behavioral, or health-related software and tools. This opportunity encourages RSEs to enhance the development of algorithms and support training for prospective users. Applications are due by 5:00 PM local time, with optional Letters of Intent recommended 30 days prior to the proposal deadline.

The Graduate Education Indigenous Scholarships, including the Aurora Indigenous Education Scholarship, support Aboriginal Australians and Torres Strait Islanders to pursue full-time graduate studies in the US. Offering up to $40,000 for living and educational expenses, this initiative encourages Indigenous individuals to engage in Masters, Ph.D., or Postdoctoral Research. Applicants must be Australian citizens or permanent residents, actively seeking placement in accredited institutions, and plan to study for at least one year.

The National Scleroderma Foundation's New Investigator Grant aims to support emerging researchers dedicated to scleroderma studies. This three-year grant, totaling $200,000, encourages applicants with doctoral degrees and postdoctoral experience. Eligible candidates are invited to submit proposals that may lead to further research funding. The grant emphasizes innovative research approaches while providing essential financial support for early-career investigators. Note that the grant does not cover certain costs, ensuring focused investment in research advancement.

The PCC Rapid Response Grants provide support for cultural initiatives that aim to shape narratives during critical cultural moments. These grants prioritize projects that engage communities of color, immigrants, refugees, and other marginalized groups, focusing on intersectionality, gender justice, and social equity. Eligible projects include pop culture campaigns, research, and public spectacles that respond to urgent political and cultural events, aiming to reach mass audiences and disrupt harmful narratives.