Best Grants for New Nonprofits in North Carolina

The Small Business Transition Grant for New Entrepreneurs, offered by the NIH, supports the career development of new investigators transitioning into entrepreneurship. It focuses on training and mentoring Program Directors/Principal Investigators in small business environments, enhancing their research and entrepreneurial skills. This grant is aimed at scientists with strong backgrounds in research and technology but limited experience in leading independent projects. The initiative ultimately seeks to foster innovative technologies that align with NIH's health improvement mission.

The A.J. and Sigismunda Palumbo Charitable Trust supports organizations committed to enhancing the lives of children and young adults. They focus on educational institutions, health-related initiatives, and community services in the St. Marys, Pennsylvania area. Grants are awarded to 501(c)(3) organizations demonstrating accountability and measurable outcomes, with a preference for projects that benefit the community at large. The Trust encourages collaborative funding efforts and endeavors that inspire hope and vision.

The Rural Communities Opioid Response Program (RCORP) - Community Systems Development aims to enhance behavioral health systems in rural areas by providing funding for the development and expansion of services. This initiative supports the establishment of formalized networks to boost operational and clinical capacity, ensuring effective implementation of evidence-based substance use disorder prevention, treatment, and recovery services tailored to community needs.

Sony Corporation of America focuses its charitable giving on arts, culture, technology, and the environment, with a strong emphasis on education in these fields. It supports registered 501(c)(3) non-profit organizations while ensuring that their contributions encourage the development of the creative and technical skills essential for future workforce needs. Notably, multi-year requests and various exclusions, including those based on discrimination, are not considered.

The FY 2027 Department of War Multidisciplinary Research Program (MURI) funds U.S. academic teams engaged in innovative basic research addressing future defense challenges. Established in 1985, MURI emphasizes collaboration across multiple scientific disciplines to tackle complex, DoW-relevant issues. By fostering partnerships among faculty, postdoctoral researchers, and students, the program aims to advance the U.S. defense industrial base and nurture a skilled scientific workforce, contributing to significant breakthroughs in military technology and economic growth.

The Transport Phenomena (TP) program, supported by the National Science Foundation, aims to advance fundamental research in the transport of mass, momentum, energy, and species across various scales. This initiative focuses on innovative methodologies that enhance our understanding of single- and multiphase systems, thermodynamic processes, and combustion dynamics. By integrating theoretical, experimental, and computational approaches, TP seeks to connect microscale phenomena with broader engineering applications, ultimately contributing to national priorities in energy, biotechnology, and environmental sustainability.

The Community Foundation for a Greater Richmond

The Community Foundation of Richmond is a philanthropic organization dedicated to improving quality of life across the Richmond region by connecting people, ideas, and resources for lasting community impact. The Foundation manages charitable funds, supports local nonprofits, and leads strategic initiatives that address community priorities such as education, health, economic opportunity, and equity. Through grantmaking, donor services, and community leadership, the Foundation works to strengthen nonprofits, respond to emerging needs, and build a more resilient, inclusive, and thriving Richmond-area community.

Virginia Urology Center Scholarship

The Virginia Urology Center Scholarship Program was established in 1999 to benefit graduating seniors from public and private high schools in communities where Virginia Urology offices are located, including Metropolitan Richmond, the Tri-Cities, Northern Neck, Middle Peninsula and South Hill. The scholarship supports post-secondary study in the fields of science and medicine. Funds awarded will help to cover the costs of tuition, room, board, books and laboratory fees.

The Mary Alice Warren Community Center Programming Grants support nonprofit organizations in providing affordable and accessible programs in Lewisville. This initiative, partially funded by the Arts Council of Winston-Salem and Forsyth County, aims to enrich community engagement through diverse programming. Eligible applicants must be IRS-registered 501(c)(3) organizations or governmental agencies with a proven track record. Programs focusing on seniors, arts, and community events are preferred, while film screenings and individual projects are ineligible.

The National Institute of Environmental Health Sciences (NIEHS) is launching a funding opportunity for research hubs focused on the health impacts of extreme weather. This initiative encourages multidisciplinary teams to engage with community partners on issues such as wildfire smoke and extreme heat. Emphasizing collaboration, the program aims to develop scalable solutions and measurable public health outcomes, leveraging resources and expertise across institutions to address climate-related health challenges effectively.

About Us

Marshfield Area Community Foundation, Inc. is a public, 501-C-3 charity. There are 30 community foundations in Wisconsin and more than 750 in the nation. The purpose of all community foundations is to accumulate charitable dollars that impact a specific geographic region in areas such as education, the arts, economic development, recreation, environmental protection, health care, and social services. They may be relatively small, as we are (assets of $14 million), or very large, as is the Greater Milwaukee Foundation (assets over $400 million).

Most people are familiar with private foundations, established by individuals, families, or corporations. Typically, in order to establish a private foundation, one has to have considerable wealth. You could say Community Foundations are much more democratic. We are, in a sense, an umbrella foundation containing many small foundations. We call those small foundations “funds.”

Marshfield Area Community Foundation Scholarships

The mission of the Marshfield Area Community Foundation is “Connecting people who care with causes that matter to enrich the quality of life in the Marshfield area”. Education is a valuable tool and a cause that matters to all of us. Through assisting students with financial support to receive an education, not only do students and the families of those students benefit, but also our community benefits, which further allows us to achieve our mission of enriching the quality of life in the Marshfield area.

Staab Construction Scholarship (2025)

About Us

The Food Allergy Fund is the leading nonprofit dedicated to funding food allergy research. FAF's grants support the creation of new treatments that will address the root causes of food allergies. Through our ground-breaking research and unique thought leadership summits, we accelerate innovation to find solutions.

Food Allergy Fund Drug Repurposing Program

Grants will be awarded to research teams that propose innovative approaches to repurposing therapeutics for the prevention or treatment of food allergy. We would welcome proposals identifying either an existing FDA-approved drug or drug in development with human safety data that has a rationale for the prevention of food allergies, prevention or treatment of food induced anaphylaxis, or an improved method for maintaining food allergic tolerance in previously allergic patients.

We are particularly interested in either small molecule drugs or biologicals that have well defined mechanisms of action that provide a scientific rationale for use in food allergies. Examples could involve drugs such as enzyme inhibitors or immunomodulators with specific activities that lend themselves to alter intestinal, mucosal or immune function.

About The NRA Foundation

The heart of The NRA Foundation’s mission is preserving the core of our American values and traditions in our steadfast effort to Teach Freedom.

The NRA Foundation Supports Freedom, Family, and the Future of the Shooting Sports

Established in 1990, The NRA Foundation, Inc. (“NRA Foundation”) is a 501(c)(3) tax-exempt organization that raises tax-deductible contributions in support of a wide range of firearm-related public interest activities of the National Rifle Association of America and other organizations that defend and foster the Second Amendment rights of all law-abiding Americans.

The heart of The NRA Foundation’s mission is preserving the core of our American values and traditions in our steadfast effort to Teach Freedom.

Established in 1990, The NRA Foundation, Inc. (“NRA Foundation”) is a 501(c)(3) tax-exempt organization that raises tax-deductible contributions in support of a wide range of firearm-related public interest activities of the National Rifle Association of America and other organizations that defend and foster the Second Amendment rights of all law-abiding Americans. These activities are designed to promote firearms and hunting safety, to enhance marksmanship skills of those participating in the shooting sports, and to educate the general public about firearms in their historic, technological and artistic context. Funds granted by The NRA Foundation benefit a variety of constituencies throughout the United States including children, youth, women, individuals with physical disabilities, gun collectors, law enforcement officers, hunters and competitive shooters.

Awards

The NRA is proud to recognize the contributions of those who have demonstrated dedication to the promotion of the Second Amendment, significantly impacted the preservation of the shooting sports, advanced the purposes and goals of the NRA and exemplified leadership through public service. Each year, women, youth, clubs, law enforcement officers and NRA Foundation volunteers are awarded for their efforts in pursuit of these principles.

NRA Sybil Ludington Women's Freedom Award

This national award is in honor of the brave woman, Sybil Ludington, who in 1777, galloped on her horse one night to rally troops against the British. Now to honor her accomplishment and the accomplishments of modern heroines, the NRA bestows the prestigious Sybil Ludington Women’s Freedom Award in her name.

The ASTR Translation Prize recognizes the vital contributions of translators in theater and performance studies. It honors an exceptional English translation of works such as plays, performance texts, scholarly books, and articles published in the last calendar year. The award includes a $500 honorarium and free registration to the annual ASTR conference, promoting the importance of translations in enhancing the global theater landscape.

The Musician Health & Services Program, funded by The Jeremy Willson Charitable Trust, provides essential support for professional musicians facing financial hardships due to medical or mental health issues. This program offers navigation assistance to help applicants access healthcare resources and financial aid for living and medical expenses. Eligible participants include musicians and music industry professionals residing in Oregon or Clark County, Washington. The program aims to alleviate the financial burdens associated with medical treatments and living costs.

The Community Foundation of the Rappahannock River Region

The Community Foundation is a devoted advocate for the vitality and well-being of the Rappahannock River Region. We are a 501(c)(3) nonprofit that manages and distributes charitable giving in the counties of Stafford, Spotsylvania, King George, and Caroline, and the City of Fredericksburg.

Scholarships

One of The Community Foundation’s strategies for preserving and growing the quality of life in our region is supporting higher education for area students. Generous individuals and families, companies and organizations establish endowed scholarship funds and the proceeds from these funds benefit deserving students. Donors work with foundation staff to determine appropriate criteria for each fund. The Community Foundation currently administers more than fifty scholarship funds.

The Mary E. Berger Scholarship Fund

The Mary E. Berger Scholarship was established with a gift from Mary E. Berger and a future gift by the estate of Mary E. Berger to assist high school students who wish to attend college or university or professional school to pursue studies in art, music, history, political science, English, journalism and related liberal arts subject.

The OJP FY 2026 Special Attorneys Program provides funding for state, local, Tribal, and territorial prosecuting agencies to hire qualified prosecutors and support staff. These professionals will work under the National Fraud Enforcement Division to investigate and prosecute crimes committed by criminal aliens, as well as drug and human trafficking cases. This initiative aims to enhance law enforcement capabilities, improve intergovernmental coordination, and strengthen the prosecution of fraud and other serious crimes.

The NEA Foundation's Student Success Grants support educators in creating innovative learning experiences that foster critical thinking, problem-solving, and cultural understanding among students. This initiative encourages project-based and personalized learning, enabling students to engage with real-world challenges. Applicants must be members of the National Education Association and can use grant funds for educational materials and experiences. The focus is on enhancing academic skills, communication, and collaboration, ultimately promoting joy in learning.

The BJA FY 2026 Rural Violent Crime Reduction Initiative aims to empower local law enforcement in rural areas to combat violent crime effectively. This funding opportunity provides resources for personnel, technology, and data analytics to enhance crime prevention strategies. Eligible applicants can utilize updated equipment and training to address specific violent crime challenges, ensuring safer communities through innovative approaches and strategic resource allocation. Applications are due by November 6, 2026.

The Fidelity Foundation Grant supports nonprofit organizations that aim for high impact in areas like Arts, Education, and Health. Eligible applicants must be 501(c)(3) organizations with operating budgets over $1 million and project budgets of at least $100,000. The foundation seeks transformative projects that enhance efficiency and sustainability. However, it does not fund start-up organizations, capital campaigns without prior support, or emergency funding, ensuring a focus on long-term effectiveness.

The NIAID aims to enhance our understanding of the interplay between chronic and infectious diseases through innovative precision systems biology research. By utilizing advanced technologies such as multi-omics and artificial intelligence, the initiative focuses on uncovering critical pathways that connect infections to chronic health issues. This multidisciplinary approach leverages longitudinal patient data to inform and improve prevention and treatment strategies, ultimately seeking to provide insights into disease progression and host-pathogen interactions.

Timothy B. Snyder Memorial Scholarship Fund

Fund provides financial scholarships to deserving young men and women from high schools in the counties of Botetourt, Halifax and Shenandoah.

Amount

• $1,000+

The Bruce J. Heim Foundation Grant supports organizations that empower young individuals with exceptional potential in academics and the arts. Established in 1986, this private foundation aims to provide financial assistance that fosters skill enhancement and personal growth. The Board evaluates grant requests monthly, assessing the viability and significance of each organization’s project. The Foundation's goal is to inspire recipients to realize their potential and contribute to philanthropic efforts, echoing the support they received.

The Native Entities Grant Program, initiated by NTIA under the Digital Equity Act of 2021, aims to support Indian Tribes, Alaska Native entities, and Native Hawaiian organizations. This program streamlines funding through a unified application for two significant initiatives: the State Digital Equity Capacity Grant and the Digital Equity Competitive Grant. By focusing on reducing administrative burdens, it enhances access to digital resources and equity in underserved communities.

The Fox Family Foundation Grants support local nonprofits in the Durham area, emphasizing the importance of effective leadership and collaboration. The foundation provides multi-year grants for general operating support, capacity projects, and practical needs. Eligible organizations must be 501(c)(3) compliant and located in Durham, Orange, or Wake Counties. Special projects outside primary interests may also receive consideration. The foundation prefers supporting initiatives that benefit the community and foster joint efforts among nonprofits.

The Emergent Fund Grant, established in 2016, supports BIPOC-led social justice movements through rapid response funding. It addresses urgent community needs by providing low-barrier grants to organizations facing crises such as family separation and systemic oppression. The fund prioritizes initiatives that foster Black liberation, multiracial solidarity, and empower communities to build transformative power. By investing in innovative strategies, the Emergent Fund aims to challenge oppressive structures and advance social justice, ensuring that impacted communities are at the forefront of their own advocacy.

Seattle Foundation is an agent of change, igniting powerful, rewarding philanthropy to make Greater Seattle a stronger, more vibrant community for all.

At Seattle Foundation, we believe that community is more than a place. It’s the shared understanding that our joy and well-being are tied to one another. Every day we work with nonprofits, philanthropists, and partners like you to strengthen community by igniting powerful philanthropy and advancing long-term solutions. Because it takes all of us to create a joyful region where every person can thrive.

Black at Microsoft Scholarship

This scholarship supports high school seniors who self-identify as Black or African American and plan to study in Engineering, Computer Science, Computer Information Systems, Business Administration, Finance, or Marketing at an accredited four-year college or university. This scholarship varies from $2,500 to $5,000 with up to 50 awards granted.

The Climate Program Office (CPO) FY2026 Earth System Science and Services Partnership (ESSSP) aims to enhance NOAA's mission through collaborative research and activities. It focuses on understanding changes in Earth's systems and their impacts on ecosystems and communities. Eligible applicants include academic institutions offering doctoral degrees in NOAA-related sciences. The total funding available is approximately $10 million, supporting initiatives that encompass research, data evaluations, and stakeholder engagement.