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Best Grants for New Nonprofits in North Carolina

Find the perfect Grants for New Nonprofits in North Carolina on Instrumentl. 10,000+ Grants for New Nonprofits in North Carolina in the United States.

10,000+

Available grants

$2.70B

Total funding

$5K

Median grant

10,000+ grants
$2.70B total
$5K median

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9,807 Results based on applied filters

John M. O'Quinn Foundation Grant

John M Oquinn Foundation
Private
United States
Unspecified amount
The John M. O'Quinn Foundation Grant, established in 1986, has contributed over $192 million to various charitable activities, focusing primarily on Houston and its surrounding areas. The Foundation supports tax-exempt organizations and governmental units, emphasizing conservation, education, healthcare, and programs for underprivileged youth. Grants are not available for type III supporting organizations, individuals, or foreign charities, ensuring a targeted impact within the local community.
Education Environmental Conservation Youth Services +1 more

JustJane Art Scholarship Fund for Women

Saginaw Community Foundation
Private
United States
Unspecified amount

Scholarships

Since awarding our first $500 scholarship in 1987, the Saginaw Community Foundation has awarded college scholarships to area students totaling more than $13.7 million, thanks to our generous donors. Each year, over 500 college-bound or career and technical education students benefit from our scholarship awards.

Our single application process makes it easy to potentially qualify for one or more of our 260+ scholarships.

JustJane Art Scholarship Fund for Women

Truly unique humans like Jane Marie Ewing do not populate the universe very often, and the JustJane Art Scholarship for Women was created to honor her remarkable spirit.

Jane was an artist at heart, finding joy in countless creative pursuits – whether baking delectable treats, capturing life’s beauty through photography, or expressing her imagination in fashion and digital illustration. Her zest for life was infectious, often bringing laughter through her playful “Jane Pranks”, which will forever live in the hearts of family and friends. Jane shared an inseparable bond with Kyle, each the center of the other’s universe. Tragically, Jane was taken from this world unexpectedly in 2025.

Her vibrant artistic soul touched every aspect of her life – from painting and interior design to crafting costumes for parties and pranks. Though her passion for art wasn’t fully nurtured early on, once she embraced it later in life, creativity flowed freely, illuminating the lives of everyone around her. Jane saw beauty everywhere, and her art became a reflection of that vision.

This scholarship carries forward Jane’s legacy, helping future generations cultivate their own artistic passions. It is a reminder to future generations that art has the power to transform lives.

Education - Higher Education Art & Culture Fine Art +1 more

Strategies to Innovate EmeRgENcy Care Clinical Trials Network (SIREN) Infrastructure – Clinical Coordinating Center (CCC) and Data Coordinating Center (DCC)

National Institutes of Health
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The National Institutes of Health (NIH) is seeking to enhance the Strategies to Innovate EmeRgENcy Care Clinical Trials Network (SIREN) through the establishment of a Clinical Coordinating Center (CCC) and Data Coordinating Center (DCC). This initiative aims to improve emergency care outcomes by supporting trials that focus on effective treatments for non-stroke neurological and cardiovascular emergencies. Although applications are not currently being solicited, this notice allows potential applicants to prepare collaborative proposals.
Health & Medicine Cardiovascular Diseases & Systems Neurological Diseases & Disorders

Winston-Salem Foundation: Impact Investing

Winston-Salem Foundation
Private
Forsyth County, North Carolina
US $100,000 - US $1,000,000
The Winston-Salem Foundation's Impact Investing program strategically allocates funds to businesses and organizations that foster social change in Forsyth County. By focusing on both social and financial returns, the foundation aims to empower communities of color and address historical inequities. This initiative prioritizes local projects that enhance economic mobility while promoting ownership and governance by those affected, ultimately striving for a more inclusive economy and systemic change.
Economic Services & Development Community Development & Revitalization Civic Leadership Development +2 more

Kors, Lois E., Educational Scholarship

Beatrice Educational Foundation
Association/Society
United States
Unspecified amount
The Kors, Lois E., Educational Scholarship, established by the Beatrice Educational Foundation, aims to support Beatrice High School graduates in pursuing higher education. With a strong commitment to academic achievement and civic involvement, the Foundation awards over $55,000 annually in scholarships. Applicants must demonstrate financial need, citizenship, and academic merit. This scholarship encourages students to enter the teaching profession, providing essential funds to help them achieve their educational goals.
Education Education - Higher Education Academic Scholarship Programs +1 more

Congressional Fellowship

American Chemical Society
Association/Society
United States
Unspecified amount
The ACS Congressional Fellowship Program offers trained scientists the chance to engage in the policy-making process, providing critical information to lawmakers on science-related issues. Each year, two fellows are placed in the offices of Senators, Representatives, or Committees, with the aim of educating them on how science policy is formed. Candidates with a strong background in chemical sciences or engineering are encouraged to apply, regardless of whether they hold a doctorate.
Civic Engagement & Education Civic Leadership Development Civic Affairs +1 more

Intellia Therapeutics UNCF Scholarship Program

United Negro College Fund Inc
Private
United States
US $5,073
The Intellia Therapeutics UNCF Scholarship Program, in partnership with the United Negro College Fund, aims to support students pursuing careers in life sciences. With a commitment to educational equity, this program offers scholarships to eligible students who demonstrate financial need and maintain a minimum GPA of 2.75. By investing in future leaders, Intellia Therapeutics and UNCF continue to empower individuals and strengthen communities, ensuring that no mind is wasted.
Education - Higher Education Academic Scholarship Programs Biology +2 more

Artist in Business Leadership (ABL) Fellowship

First Peoples Fund
Private
United States
US $10,000
The Artist in Business Leadership (ABL) Fellowship supports Native artists in building sustainable art-centered businesses. This yearlong program provides $10,000 in funding along with professional development and networking opportunities. Eligible applicants must be 18 years or older, reside in the U.S., and be enrolled in or have lineage from a federally recognized tribe. The fellowship aims to empower artists to thrive within their communities while honoring their cultural heritage.
Art & Culture Native American Culture & Heritage Business Development

NeuroNEXT Small Business Innovation in Clinical Trials (U44 Clinical Trial Optional) (357073)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
United States
Up to US $15,000,000
The NeuroNEXT Small Business Innovation program invites small businesses to apply for exploratory clinical trials involving investigational agents, including drugs, biologics, and devices. These trials aim to gather critical data to support the design of future clinical studies, particularly focusing on diseases aligned with the NINDS strategic plan. Applications are due by 5:00 PM local time of the applicant organization, emphasizing the importance of timely submissions.
Pharmacology Neurological Diseases & Disorders Biotechnology +1 more

Knight Cities Challenge

John S And James L Knight Foundation Inc
Private
Allen County, Indiana, Baldwin County, Georgia +24 more
Up to US $200,000

About Knight Foundation

John S. and James L. Knight believed that a well-informed community could best “determine its own true interests” and was essential to a well-functioning, thriving democracy. They pursued those beliefs, building and leading one of the largest and most successful newspaper companies in American history.

For 75 years, Knight Foundation has supported the people, ideas and insights that lead to thriving communities. The foundation invests in local journalism, arts and culture and community development in the 26 cities and towns where the Knight brothers once published newspapers.

Since our founding in 1950, we have been committed to the communities we serve and to providing those communities with the tools they need for residents to thrive.

Knight Cities Challenge

Knight Foundation is currently accepting applications for the Knight Cities Challenge, a $5 million open call inviting individuals and organizations across its 26 communities to submit new, creative ideas for projects that can spark change and leave a lasting local impact.

Building on a long history of open challenges across programs, Knight democratizes access to grantmaking to unlock the best and brightest ideas. This spring, KCC returns to invest in its first cohort of community-centered solutions to local challenges and help promising ideas take root and grow.

Project ideas must focus on at least one of Knight’s investment areas: strengthening local news and information, creating pathways for economic opportunity or cultivating connection through arts, culture and the places that bring people together.

You may submit one idea, either as an individual or on behalf of your organization. While you are limited to one application as the lead applicant, you may collaborate on other projects submitted by different partners. Each individual or organization may receive funding for only one project.

For large institutions such as universities or city governments, schools or departments are considered separate entities. 

Journalism News Media & Communications Economic Services & Development +1 more

The Gryphon Scholarship Program

Scholarship America Inc
Private
United States
More than US $2,500
The Gryphon Scholarship Program, administered by Scholarship America Inc., aims to support high school seniors and recent graduates from select metropolitan areas pursuing full-time undergraduate studies. With a focus on students demonstrating financial need, this initiative aligns with Scholarship America's mission to eliminate financial barriers to education. By fostering access and affordability for underserved communities, the program empowers students to achieve their academic goals while also promoting responsible debt management in their educational journey.
Economics Education - Higher Education Career / College Preparation +1 more

Value Assessment and Health Outcomes Research Postdoctoral Fellowship

Pharmaceutical Research And Manufacturers Of America Fnd Inc (PhRMA)
Private
United States
Up to US $120,000
The Value Assessment and Health Outcomes Research Postdoctoral Fellowship, funded by the PhRMA Foundation, offers a $60,000 stipend annually for up to two years. This fellowship supports researchers, both U.S. and non-U.S. citizens, engaged in innovative studies aimed at evaluating the effectiveness and value of healthcare interventions. Applicants must be within five years of postdoctoral study and hold a relevant doctoral degree. This opportunity fosters collaboration and patient engagement in health outcomes research.
Health & Medicine Health Disparities & Social Determinants of Health Health Care Access & Delivery +1 more

CFCC: Mark C. and Dorothy I. Morgan Scholarship

Greater Salina Community Foundation
Private
United States
US $1,500 - US $2,000

Our mission is to enhance quality of life, today and in the future, by:

  • Enabling donors to fulfill their charitable desires
  • Building a permanent endowment
  • Facilitating prudent management and care of funds
  • Meeting needs through grants, awards, and scholarships

CFCC: Mark C. and Dorothy I. Morgan Scholarship

Amount

(1) $2,000 scholarship, (2) $1,500 scholarships

This scholarship is not renewable and previous recipients may not reapply.

Education Education - High School Agricultural Education

Sandusky-Firelands Alzheimer’s Scholarship

Erie County Community Foundation
Private
United States
Unspecified amount
The Sandusky-Firelands Alzheimer’s Scholarship provides financial support to residents of Erie County, Ohio, pursuing degrees in the Medical and Health Care fields, particularly those interested in working with geriatric patients. Established in 1995 by a dedicated non-profit organization, this scholarship aims to enhance community well-being and quality of life. Renewals for up to three additional years are possible, depending on financial need and the discretion of the Scholarship Advisory Committee.
Education - Higher Education Education - High School Academic Scholarship Programs +1 more

Kichler, Tony and Gertrude Scholarship Fund

Noble County Community Foundation
Private
United States
US $3,500

Community Foundation of Noble County

At the Community Foundation of Noble County we are passionate about making Noble County an even better place to call home. Since 1991, area residents have been turning to the Community Foundation of Noble County to make their philanthropic giving as effective as possible, as we see it as our mission to serve as a catalyst for positive change. The Community Foundation of Noble County is a public charity 501 (c) 3 entity.

Scholarships

The Community Foundation of Noble County offers a wide range of scholarships to support local students in achieving their academic and career aspirations. 

Kichler, Tony and Gertrude Scholarship Fund

For high school seniors or college students who reside in Green or Noble TOWNSHIPS (not county) in Noble County who are pursuing a college education in music, medicine or religion. One-time payment of $3,500. May reapply.

Music Medical Education & Professional Training Religion & Spirituality +1 more

Health Workforce Research Center (HWRC)

US HHS: Health Resources & Services Administration (HRSA)
Federal Government
American Samoa, Guam +4 more
US $450,000 - US $900,000
The Health Workforce Research Center (HWRC) aims to enhance understanding of health workforce needs across various levels of governance. Funded by the US HHS: Health Resources & Services Administration (HRSA), this initiative supports vital research that informs decision-makers, ensuring effective resource allocation and workforce planning to meet healthcare demands.
Health & Medicine Workforce Preparation & Job Readiness

Value Assessment and Health Outcomes Research Predoctoral Fellowship

Pharmaceutical Research And Manufacturers Of America Fnd Inc (PhRMA)
Private
United States
Up to US $60,000
The Value Assessment and Health Outcomes Research Predoctoral Fellowship, offered by the PhRMA Foundation, supports promising students in their advanced training and thesis research. This fellowship, aimed at U.S. and non-U.S. citizens, provides $30,000 in annual stipend support for up to two years. It encourages research proposals that address the effectiveness, safety, and value of healthcare interventions, emphasizing patient engagement and health equity in the evaluation process.
Health & Medicine Health Care Access & Delivery Health Disparities & Social Determinants of Health +1 more

Salisbury-Rowan Community Foundation Grant

Foundation for the Carolinas
Private
Rowan County, North Carolina
Up to US $10,000
The Salisbury-Rowan Community Foundation Grant aims to enhance local community welfare by funding projects that address pressing needs in Salisbury and Rowan County. With a focus on arts, animal welfare, health care, and education, the Foundation supports measurable initiatives that demonstrate effective use of funds. Grants can range from $2,500 to $10,000, and priority is given to innovative programs that do not duplicate existing services. Eligible organizations include non-profits and educational institutions.
Art & Culture Education - K through 12 Education - Higher Education +3 more

Vilcek Foundation Grants

The Vilcek Foundation Inc
Private
American Samoa, Guam +4 more
US $5,000 - US $20,000
The 2025 Vilcek Foundation Grants aim to support nonprofit organizations that celebrate immigrant contributions to the arts and sciences. The foundation invites applications from organizations operating under U.S. IRS Section 501(c)(3) that promote diversity and inclusivity. Grants will be prioritized for new partners and those in states without prior funding. This initiative underscores the foundation's commitment to fostering appreciation for immigrant communities and their impact on society.
Immigrant Services Art & Culture Education - Higher Education +1 more

Focused Technology Research and Development (R01 Clinical Trial Not Allowed) (357112)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The Focused Technology Research and Development (R01) grant supports innovative projects aimed at developing technologies to enhance biomedical research. This funding opportunity emphasizes the creation of laboratory instruments, algorithms, and biological systems that can significantly improve research capabilities. Key deadlines for applications are set for February, June, and October of 2025 through 2027, ensuring ample time for proposal submissions. The initiative is funded by the National Institutes of Health (NIH), part of the US Department of Health and Human Services.
Biotechnology Biomedical Imaging Medical Technology, Devices, and Equipment +1 more

SUS: Resident Research Scholar Award

Society of University Surgeons
Private
Canada, United States
US $30,000
The SUS Resident Research Scholar Award offers $30,000 for one year to surgical residents engaged in basic or translational research. Eligible candidates must have completed two years of training and commit to full-time research with an SUS member. Notably, applicants must avoid mentors on the exclusion list, ensuring a fair and competitive application process. This funding promotes innovative surgical research and supports the development of future leaders in the field.
Surgery Bioengineering Health Information Technology +1 more

August Corso Scholarship Fund

Erie County Community Foundation
Private
United States
Unspecified amount

August Corso Scholarship Fund

Scholarships shall be awarded to residents of Erie County, Ohio pursuing a post-secondary education. Preference shall be given to students pursuing a degree in Horticulture, Environmental Science or Agricultural Business. Financial need is a consideration for the scholarship award.

Scholarships are available for students planning to attend an accredited nonprofit college or university, or planning to receive licensure, accreditation, or a certificate from a nonprofit vocational or apprenticeship program in the United States.

The scholarship may be renewed for a second, third, and fourth year.

Education - Higher Education Environmental Education Horticulture & Gardening +1 more

NOI: PROSPECT Program: Providing Opportunities for Specialized Education in Critical Technologies

United States Department of Energy (DOE)
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The U.S. Department of Energy (DOE) is launching the PROSPECT Program to enhance education in critical technologies, targeting an investment of up to $100 million. This initiative aims to develop a skilled workforce across the critical minerals and materials sector, supporting the entire value chain from resource extraction to recycling. By fostering collaboration among academia, industry, and national laboratories, the program seeks to strengthen U.S. economic competitiveness and energy security.
Education Natural Resources

Actions of Public Witness Grant

Unitarian Universalist Association
Association/Society
Canada, Mexico +1 more
Up to US $1,500
The Actions of Public Witness Grant, offered by the Unitarian Universalist Funding Program, provides matching grants of up to $1,500 to Unitarian Universalist congregations engaging in timely actions of public witness. This initiative supports efforts in social and environmental justice, encouraging congregations to mobilize during critical moments. Grants are available on a rolling basis and are intended for urgent projects that extend beyond the regular grant timeframe. Notably, individual applications are not accepted.
Environmental Justice & Advocacy Social Justice / Human Rights Outdoor Equity

Dennis Schuman Charitable Foundation Grant

Dennis Schuman Charitable Foundation
Private
United States
Unspecified amount
The Dennis Schuman Charitable Foundation Grant supports qualified Jewish organizations and charities in the United States, focusing on arts, education, health, human services, public benefit, and religion. Established by Dennis Schuman, the foundation continues his philanthropic legacy, providing funding exclusively for charitable, religious, scientific, literary, or educational purposes. Organizations must be exempt under Section 501(c)(3) of the Internal Revenue Code to qualify for funding.
Art & Culture Education Health & Medicine +5 more

The Karim Thomas Ziyad Memorial Engineering Scholarship Fund

Community Foundation of Washington County Maryland
Private
United States
Unspecified amount
The Karim Thomas Ziyad Memorial Engineering Scholarship Fund supports students from Washington County or nearby areas pursuing a career in engineering, especially in Mechanical Engineering. Established in memory of Karim Thomas Ziyad, this scholarship aims to empower deserving students to achieve their educational goals. The fund is part of the Community Foundation of Washington County Maryland, which offers numerous scholarships to enhance educational opportunities for local students.
Education - Higher Education Mechanical Engineering Education - High School +1 more

M.A. Essay Prize

The North American Conference On British Studies Inc
Private
Canada, United States
US $500
The M.A. Essay Prize, awarded by the North American Conference on British Studies (NACBS), recognizes exceptional original research by students in stand-alone M.A. programs in the U.S. and Canada. With a prize of $500, it encourages scholarly excellence and invites winners to submit their work for publication. Faculty nominations are required, ensuring deserving candidates receive recognition for their academic contributions, thereby fostering a vibrant academic community within British studies.
Anthropology & Cultural Studies Writing & Literature European Art +1 more

Grants for New Nonprofits in North Carolina Highlights

Looking for grants for new nonprofits in North Carolina?


Read more about each grant below or start your 14-day free trial to see all grants for new nonprofits in North Carolina recommended for your specific programs.

Last updated: October 5, 2026. Next update: November 1, 2026.

Grant Insights : Grants for New Nonprofits in North Carolina

Grant Availability

How common are grants in this category?

Common — grants in this category appear regularly across funding sources.

200+ Grants for New Nonprofits in North Carolina grants for nonprofits in the United States, from private foundations to corporations seeking to fund grants for nonprofits.

70 Grants for New Nonprofits in North Carolina over $25K in average grant size

51 Grants for New Nonprofits in North Carolina over $50K in average grant size

35 Grants for New Nonprofits in North Carolina supporting general operating expenses

200+ Grants for New Nonprofits in North Carolina supporting programs / projects

3,000+ Grants on Instrumentl focused on Education

1,000+ Grants on Instrumentl focused on Workforce Preparation & Job Readiness

Grant Deadline Distribution

Over the past year, when are grant deadlines typically due for grants for New Nonprofits in North Carolina?

Most grants are due in the first quarter.

Q1
30.4%
Q2
22.4%
Q3
26.2%
Q4
21.1%

Typical Funding Amounts

What's the typical grant amount funded for Grants for New Nonprofits in North Carolina?

Grants are most commonly $17,500.

$500 $500 Min.
$17,500 $17.5 K Median
$477,452 $477.5 K Average
$40,331,313 $40.3 M Max.

Average Grant Size

What's the typical amount funded for North Carolina?

Grants are most commonly $131,121.

$131,121

Total Number of Grants

What's the total number of grants in Grants for New Nonprofits in North Carolina year over year?

In 2024, funders in North Carolina awarded a total of 70,602 grants.

2022 63,850

2023 62,335

2024 70,602

Top Grant Focus Areas

Among all the Grants for New Nonprofits in North Carolina given out in North Carolina, the most popular focus areas that receive funding are Education, Human Services, and Philanthropy, Voluntarism & Grantmaking Foundations.

1. Education

2. Human Services

3. Philanthropy, Voluntarism & Grantmaking Foundations

Funding Over Time

How is funding for Grants for New Nonprofits in North Carolina changing over time?

Funding has increased by 15.49%.

2022 $7,927,620,616

2023 $7,987,830,464
0.76%

2024 $9,224,796,270
15.49%

North Carolina Counties That Receive the Most Funding

How does grant funding vary by county?

Durham County, Orange County, and Mecklenburg County receive the most funding.

County Total Grant Funding in 2024
Durham County $2,942,551,198
Orange County $2,549,339,233
Mecklenburg County $1,468,677,341
Wake County $1,122,908,782
Buncombe County $444,853,701

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