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Find the perfect Operating grants for nonprofits in North Carolina on Instrumentl. 10,000+ Operating grants for nonprofits in North Carolina in the United States.
10,000+
Available grants
$2.78B
Total funding
$5K
Median grant
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Scholarships support aspiring college students who hold the promise of tomorrow’s progress.
Together, our competitive grants and scholarships help our region rise thanks to the vision and generosity of our donors.
Frank and Marie Cleary Memorial Scholarship Fund
Scholarships support aspiring college students who hold the promise of tomorrow’s progress.
Together, our competitive grants and scholarships help our region rise thanks to the vision and generosity of our donors.
The Sampson Scholarship Fund
This scholarship is for a Year 3 or Year 4 veterinary school student or resident committed to Zoological or Wildlife Medicine.
About Patient Advocate Foundation
Patient Advocate Foundation is the nation’s most comprehensive nonprofit dedicated to helping patients navigate, access, and afford the care they need—while improving the healthcare system for all.
Who we are and our impact
Patient Advocate Foundation provides financial assistance to help patients afford treatment and cost of living needs, personalized case management to navigate complex healthcare and social needs challenges, and a wide array of resources to empower people to take charge of their health. Since our founding in 1996—and joining forces with the PAN Foundation in 2026—we have helped 3.8 million patients navigate and access care, granted over $7 billion in financial assistance, served 350,000 people through personalized case management and elevated the patient’s voice to drive improvements in the healthcare system.
Cushing’s disease or syndrome
Help with healthcare costs for Cushing's disease or syndrome
This TotalAssist fund helps you pay for out-of-pocket healthcare costs, including medication copays, coinsurance, and deductibles, health insurance premiums, and other expenses.
About the disease
Cushing’s Disease or Syndrome, also known as Cushing’s Syndrome, hypercortisolism and hyperadrenalism, is a condition where the pituitary gland releases high levels of the hormone cortisol. It is a rare disease that affects the endocrine system.
About Patient Advocate Foundation
Patient Advocate Foundation is the nation’s most comprehensive nonprofit dedicated to helping patients navigate, access, and afford the care they need—while improving the healthcare system for all.
Who we are and our impact
Patient Advocate Foundation provides financial assistance to help patients afford treatment and cost of living needs, personalized case management to navigate complex healthcare and social needs challenges, and a wide array of resources to empower people to take charge of their health. Since our founding in 1996—and joining forces with the PAN Foundation in 2026—we have helped 3.8 million patients navigate and access care, granted over $7 billion in financial assistance, served 350,000 people through personalized case management and elevated the patient’s voice to drive improvements in the healthcare system.
Amyloidosis
Help with healthcare costs for amyloidosis
This TotalAssist fund helps you pay for out-of-pocket healthcare costs, including medication copays, coinsurance, and deductibles, health insurance premiums, and other expenses.
About the disease
Amyloidosis is characterized by a build-up in amyloid protein in specific organs or throughout the body. It is a rare disease that affects multiple systems. Subtypes include hereditary amyloidosis, light chain amyloidosis (AL amyloidosis), and amyloid A (AA) amyloidosis (secondary amyloidosis).
Looking for operating grants for nonprofits in North Carolina?
Read more about each grant below or start your 14-day free trial to see all operating grants for nonprofits in North Carolina recommended for your specific programs.
How common are grants in this category?
Common — grants in this category appear regularly across funding sources.
Over the past year, when are grant deadlines typically due for Operating grants for Nonprofits in North Carolina?
Most grants are due in the first quarter.
What's the typical amount funded for North Carolina?
Grants are most commonly $131,121.
What's the total number of grants in Operating Grants for Nonprofits in North Carolina year over year?
In 2024, funders in North Carolina awarded a total of 70,602 grants.
Among all the Operating Grants for Nonprofits in North Carolina given out in North Carolina, the most popular focus areas that receive funding are Education, Human Services, and Philanthropy, Voluntarism & Grantmaking Foundations.
1. Education
2. Human Services
3. Philanthropy, Voluntarism & Grantmaking Foundations
How is funding for Operating Grants for Nonprofits in North Carolina changing over time?
Funding has increased by 15.49%.
How does grant funding vary by county?
Durham County, Orange County, and Mecklenburg County receive the most funding.
| County | Total Grant Funding in 2024 |
|---|---|
| Durham County | $2,942,551,198 |
| Orange County | $2,549,339,233 |
| Mecklenburg County | $1,468,677,341 |
| Wake County | $1,122,908,782 |
| Buncombe County | $444,853,701 |