Best Private Grants for Nonprofits in North Carolina

About the Foundation

Our Mission

Beyond Batten Disease Foundation was established to eradicate juvenile Batten disease by raising awareness and funds to accelerate research for a treatment or cure.

About Funding

BBDF is dedicated to collaboratively developing, funding, and managing fundamental, preclinical, IND-enabling, translational and clinical research to improve the lives of children and young adults with CLN3 disease. Since 2008, BBDF has been the largest funder of juvenile Batten (CLN3) disease research, ranging from basic discovery research to translation into therapies. To inform our research initiatives, BBDF gathers information from one-on-one meetings, broad group discussions, scientific peer-reviewed publications, conference proceedings, drug pipelines, and tailored merit reviews into the foundation’s decision-making processes. Input comes from across the Research and Development spectrum including academia, biotechnology, the pharmaceutical sector, and clinicians, caregivers, and patients.

Our research funding decisions are based on these research objectives:

1) Supporting basic research to discover new mechanisms of disease, targets, and treatments

2) Supporting projects which facilitate execution of clinical trials such as expanding patient registries

3) Identifying biomarkers and other innovative clinical endpoints

4) Supporting projects that de-risks pharmaceutical investments in Batten disease

Foundation-Directed Research

The largest portion of the foundation’s portfolio is directed research. The foundation fills gaps in juvenile Batten disease research by funding high-impact projects and breakthrough technologies that will lead to disease mitigation and cure.

BBDF’s Principal Scientist regularly interacts with leaders in research and development across the entire therapeutic pipeline for Batten, as well as for adult forms of neurodegeneration (e.g., Alzheimer’s and Parkinson’s disease), and other related rare genetic diseases. To supplement this dialogue, BBDF creates specialty boards and steering committees to lead the development of its projects. A specialty board typically comprises ~200 years of combined experience specific to the proposed activity.

Investor-Initiated Research (Applying for a research grant)

In addition to directed research, BBDF accepts and awards research proposals. Because great ideas do not follow a schedule, we do this on a rolling submission basis. All budgets are carefully reviewed along with the proposed body of work. Applicants may be asked to revise their budgets and/or allow BBDF to share a summary of the proposal with other funders for the purpose of gathering additional support. Sometimes, the foundation will offer the applicant additional funding to incorporate additional expertise or methods into his or her plan.

The Francis R. Dewing Foundation Grant provides seed money to support innovative projects in early childhood education, benefiting children up to sixth grade. Founded by Frances R. Dewing in 1963, the foundation aims to stimulate intellectual growth in young children through unique educational methods. Grants typically range from $1,000 to $25,000, with a focus on projects that demonstrate a broad impact on the educational community. Applications are accepted from 501(c)(3) nonprofit organizations and government entities across the United States.

The WGPF: National Register Signage Grant Program, administered by the William G Pomeroy Foundation, aims to support public properties and historic districts in the U.S. that are listed on the National Register of Historic Places. By providing grants for signage, the program helps these sites commemorate their historic significance and share their achievements with the community, fostering awareness and appreciation for the nation's heritage.

The Warren L. and Florence W. Calvert Memorial Scholarship Fund, established in 1974, supports deserving geological students pursuing graduate studies in Economic Geology. Awarded first in 1978, the fund is sustained by contributions from HGS members and investment returns. Recipients, selected based on academic merit and endorsements from Earth Science professionals, must carry a minimum of 9 credit hours and can renew for subsequent years with satisfactory progress.

The Established Clinician Investigator Award to Support Mentoring (KS1) is designed to provide established clinician investigators with dedicated time for mentoring early-career clinician research scientists. This initiative by the US Dept. of Health & Human Services: National Institutes of Health (NIH) aims to enhance the quality of mentorship, fostering the development of future leaders in clinical research. It supports a sustained commitment to training and guidance, ensuring a robust pipeline of skilled professionals.

The Mentored Career Transition Award (KT1/R00) offers a biphasic funding opportunity for up to 5 years, supporting the transition of postdoctoral researchers to independent faculty positions. The first phase provides 1-2 years of mentored career development, while the second phase grants up to 3 years of independent research support, contingent upon satisfactory progress and faculty appointment. This grant aims to enhance the capacity of early-career researchers in achieving research-intensive roles.

The Mentored Clinician Research Scientist Career Development Award (KC1) from the NIH supports clinician research scientists for up to five years, providing dedicated time for intensive research career development. This award aims to guide candidates with clinical doctoral degrees towards achieving research independence by pairing them with experienced mentors who can help navigate their career paths.

The Mentored Research Scientist Career Development Award (KR1) offers crucial support for researchers aiming for independence. Funded by the US Dept. of Health & Human Services through the NIH, this award allows candidates to engage in intensive research training under a mentor's guidance for up to five years. It is designed for those with research doctoral degrees, facilitating their transition into independent research roles and enhancing their contributions to the scientific community.

The Rural Health Network Development Planning Program aims to enhance rural health care by fostering integrated health care networks. It focuses on collaboration among entities to bolster local capacity and improve care coordination in underserved areas. By achieving efficiencies and expanding access to essential services, the program seeks to strengthen the overall rural health system while promoting the use of health information technology and exploring innovative care delivery models.

The Rural Health Network Development Program aims to enhance health care access in rural areas by supporting integrated health care networks. It offers two funding tracts: the Network Advancement Tract for established networks to overcome operational barriers and the Network Development Tract for early-stage networks to plan and expand services. Both tracts focus on improving care coordination, health outcomes, and operational efficiency, thereby strengthening the rural health care system.

Helen Frankenthaler Foundation Inc

The Helen Frankenthaler Foundation supports the artist’s legacy through a variety of initiatives, including exhibitions, loans of artworks, research and publications, conservation, grants, educational programs for the public and the scholarly community, and the publishing of a catalogue raisonné. It is dedicated to promoting greater public interest in and understanding of the visual arts.

Established and endowed by the artist during her lifetime (1928-2011), the Foundation became active in 2013, on the closing of Frankenthaler’s estate. As the principal beneficiary of Frankenthaler’s estate, the Foundation maintains an extensive collection of her work in a variety of mediums, as well as her collection of works by other artists and original papers and materials pertaining to her life and work.

Cultural Resilience Grant

The Helen Frankenthaler Foundation supports public engagement with the visual arts through philanthropic, educational, curatorial, and research initiatives. It has expanded its grantmaking to sustain museums and visual arts institutions, supporting exhibitions, scholarship, and education across the field. The Foundation’s grantmaking priorities are currently organized across three areas:

• Climate Action and Sustainability
• Visual Arts & Education
• Cultural Resilience
  • Unrestricted support to sustain institutional capacity and core programming across the visual arts field. 
  • The Foundation provides unrestricted support to organizations whose core work is centered in the visual arts. These grants are intended to sustain exhibitions, programs, and institutional activities; support staffing, operations, and organizational capacity; and to maintain continuity during periods of reduced public funding and broader pressures affecting the arts and culture sector.
    • Cultural Resilience support is not project-based and does not require a defined initiative. 

The NSF MPS Chemistry Research Programs support groundbreaking research in chemical sciences, encompassing areas such as chemical catalysis, measurement, imaging, and theory. This initiative encourages innovative proposals that can lead to transformative advancements, without the necessity of immediate commercial applications. Researchers interested in exploring foundational concepts that could shape the future of chemistry are invited to submit their ideas for funding.

The ONR FY27 Young Investigator Program invites cutting-edge research proposals in priority areas that align with the interests of ONR Program Officers. This federal funding opportunity aims to support innovative projects led by early-career researchers, fostering advancements in science and technology relevant to the Navy. Interested applicants can find detailed eligibility criteria and contact information on the ONR website, encouraging collaboration and engagement in impactful research.

About Us

For over three decades, the Hamilton Education Foundation (HEF) has been sparking innovation and expanding horizons within our classrooms. Since 1991, this community-powered non-profit has channeled more than $2.5 million from passionate individuals, local businesses, and forward-thinking organizations directly into the hands of Hamilton’s students and teachers. 

By funding transformative workshops, creative projects, and classroom grants, HEF doesn't just support education—it inspires students to dream bigger, rewards academic excellence, and builds a stronger, more vibrant community.

Our Vision

The vision of the Hamilton Education Foundation is to assist in achieving creative and academic excellence for the 21st Century through funding activities and projects for students and educators in the Hamilton School District.

Our Mission

Our mission, in partnership with the community, is to fund, Enhanced, Extended, and Enriched learning opportunities for students and educators in the Hamilton School District.

Student Grants

Evaluation Factors

Applications are reviewed based on:

About Panorama GlobalPanorama Global is a social impact nonprofit that empowers changemakers through radical collaboration. We help our partners navigate the winding path from vision to impact. 

What We Do

• Collaboratives - Hosting and supporting collaborative efforts to achieve common goals.
• Fiscal Sponsorship - Financial and administrative support providing lean operating models to jumpstart projects.
• Funds - Philanthropic vehicles to manage and distribute funds that fuel global initiatives.

About  Innovative Postsecondary Models Fund

The Innovative Postsecondary Models (IPM) Fund supports innovative postsecondary education models that are rethinking how education is designed, delivered, financed, and assessed for learners in the United States.

The Fund is interested in innovations that benefit all learners, but especially learners whom the data show encounter the greatest obstacles to opportunity. The goal of this Fund is not only to provide funding to innovative models, but also to learn from selected grantees on how to reduce barriers to postsecondary access and increase student success outcomes to help inform the role philanthropy can play in supporting higher education innovation.

What We're Funding

We are seeking innovative postsecondary education models that demonstrate, or have the potential to demonstrate, meaningful improvements in how learners access, experience, and benefit from postsecondary education. We seek approaches with the potential to scale, influence the field, and inform how postsecondary education evolves nationally.

To help illustrate the types of innovations we hope to support, we have organized this opportunity around four broad themes. These themes reflect key dimensions of postsecondary innovation that have the potential to improve learner outcomes and inform broader systems change.

All four themes are grounded in a shared principle: student-centeredness. Truly innovative postsecondary models must be designed around learner needs, especially the needs of learners whom the data show face the greatest barriers to access and success in traditional postsecondary education.

Applicants are not expected to address all four themes, but should demonstrate strong alignment with at least one of the following:

Reimagining Instructional Design, Delivery, Assessment, and Student Support

• What success might look like:
  • Innovative instructional models improve student persistence, completion, and post-completion success, particularly for historically underserved learners, while maintaining or reducing costs.
  • Learners benefit from personalized, adaptive instruction and competency-based assessments that enable them to demonstrate and document skills in ways that are recognized by employers and other educational institutions.

Advancing Affordability and Financial Sustainability

• What success might look like:
  • Learners spend less overall, face reduced financial risk, and access high-quality education pathways that lead to credentials supporting economic mobility.
  • Successful models demonstrate affordability not only through reducing costs for learners, but also by maintaining or reducing the cost of delivering high-quality education through sustainable, efficient approaches.

Career and Workforce Alignment

• What success might look like:
  • Work and learning are more demonstrably connected and flexible, with evidence that skills are more directly tied to credentials and real career opportunities.

Removing Barriers for Underserved Learners

• What success might look like:
  • More learners from backgrounds and communities who the data show have faced the greatest barriers to accessing postsecondary education are able to access, complete, and benefit from high-quality credentials.

The Pets in the Classroom Grant Program provides financial support to educators in the US and Canada, enabling them to incorporate small animals into their classrooms. This initiative aims to enhance students' educational and personal development through direct interaction with pets. The program, established by the Pet Care Trust, invites applications from teachers, librarians, and other school staff who support student learning, fostering a nurturing environment for young learners.

The Bright Ideas Education Grants program, supported by North Carolina’s Electric Cooperatives, empowers K-12 teachers to implement innovative projects in classrooms. With applications open from April to September, educators can seek funding for creative learning initiatives. Annually, around 600 grants are awarded, enhancing educational experiences across diverse disciplines. This initiative not only enriches classroom instruction but also strengthens community ties, demonstrating the cooperatives' commitment to improving quality of life for local students.

The National Geographic Content Scholarship, offered by the United Negro College Fund, supports juniors and seniors from Historically Black Colleges and Universities. Recipients receive a $10,000 award and participate in a one-week immersion program with National Geographic, gaining valuable industry experience and mentorship. This program seeks passionate individuals interested in creative storytelling and environmental advocacy, promoting diversity and inclusion within the media field.

The U.S. Embassy in Tokyo is launching a competition to promote study abroad programs for Japanese students seeking graduate education in the United States. This initiative invites proposals from American and Japanese non-profit organizations to create innovative programs aimed at increasing enrollment of Japanese students in U.S. graduate schools across various fields, enhancing cross-cultural exchange and educational opportunities.

The Lemelson Foundation Grant supports initiatives in invention education and entrepreneurship, aiming to empower young inventors and foster innovation. With over $300 million provided since its inception, the Foundation focuses on strengthening ecosystems for invention in the U.S. and developing countries. Organizations interested in aligning with their mission are encouraged to take an eligibility quiz and submit inquiries through their contact form. This commitment is crucial for driving impactful solutions to global challenges.

The Kids to Parks Day School Grants Program offers funding up to $1,000 for Title I schools in the U.S. to enhance student engagement with parks and public lands. This initiative encourages hands-on learning experiences through outdoor activities and stewardship projects, promoting environmental education and healthy lifestyles. Eligible classrooms can apply, emphasizing student involvement in the application process. The program aims to empower students and teachers to foster a deeper connection with nature and their communities.

Dennis Van der Meer Tennis Foundation

A 2021 International Tennis Hall of Famer, Dennis was the founder of the Professional Tennis Registry Foundation (PTR Foundation), now called Dennis Van der Meer Tennis Foundation, Professional Tennis Registry (PTR), and the Van Der Meer Tennis University.

Dennis Van der Meer Tennis Foundation is a nonprofit organization exempt from federal income tax under Section 501(c)(3) of the Internal Revenue Code. The Dennis Van der Meer Tennis Foundation provides support to deserving individuals and organizations globally. The foundation is also focused on bringing tennis within reach to countless people worldwide.

Natural Disaster Relief Request

The Foundation stands with tennis professionals affected by the devastating hurricanes and other natural disasters in the U.S. in 2024. If you are a tennis pro facing hardships due to recent storms, we are here to help you get back on your feet. Our assistance program provides relief and resources specifically for tennis professionals affected by these events. Together, we can rebuild stronger.

The Toshiba America Foundation offers grants to K-5 teachers in public and nonprofit private schools, funding innovative projects in math and science education. Designed to support teachers in implementing hands-on learning experiences, these grants encourage creativity and community involvement. Applicants can propose projects that enhance student engagement and foster scientific inquiry. The foundation prioritizes teacher-led initiatives, making it a valuable resource for educators aiming to enrich their classrooms and inspire young learners.

The National Institute of Mental Health (NIMH) is launching a funding opportunity to establish a research network focused on rapid-acting psychotropic interventional drugs (RAPIDs), including ketamine and psilocybin. This initiative seeks to generate real-world evidence on the effectiveness and safety of these treatments for serious mental illnesses. By addressing critical questions around their implementation in clinical practice, the NIMH aims to facilitate the safe integration of RAPIDs into healthcare, ultimately improving mental health outcomes.

The BJA FY 2026 Capital Case Litigation Initiative aims to enhance legal representation in state capital cases. By providing essential funding, this initiative supports both prosecutors and defense attorneys to ensure equitable legal processes for indigent defendants. The U.S. Department of Justice emphasizes the importance of upholding the rule of law and protecting citizens' rights. Applications are due by November 5, 2026, at 8:59 p.m. ET, marking a critical opportunity for improvement in capital case litigation.

The Carol Ann and Ralph V. Haile Jr. Scholarship Program, established by the Carol Ann and Ralph V. Haile Jr. Foundation in partnership with UNCF, supports students attending UNCF member institutions, HBCUs, or other accredited four-year colleges. This renewable merit-based scholarship aims to enhance educational opportunities for residents of specific counties in Kentucky, Ohio, and Indiana, particularly focusing on those majoring in education or STEM fields.

The BJA FY 2026 Adult Treatment Court Program aims to enhance Adult Treatment Court operations, focusing on preventing overdoses and reducing substance use among high-risk adults in the criminal justice system. The program integrates judicial supervision, substance use disorder treatment, and recovery support services to improve outcomes for participants. This funding opportunity from the U.S. Department of Justice highlights the commitment to public safety and addressing critical issues like the opioid crisis.