Best Large Grants for Nonprofit Organizations in North Dakota

The Patient-Centered Outcomes Research Institute (PCORI) Funding Announcement aims to enhance methods for conducting patient-centered comparative clinical effectiveness research. This initiative seeks to address critical methodological gaps, focusing on improving the use of artificial intelligence in clinical research, study design, data research networks, and ethical protections in patient-centered CER. With a budget of up to $750,000, successful proposals will contribute to the quality and strength of evidence generated in CER studies.

The NIH Science Education Partnership Award (SEPA) fosters innovative educational initiatives aimed at pre-college students, promoting their interest in STEM fields, especially in biomedical and behavioral sciences. This program supports both classroom projects and informal science education activities, such as after-school programs and library events. Emphasizing the development of quantitative and computational skills, SEPA seeks to inspire the next generation of scientists and thinkers through engaging educational experiences.

The Patient-Centered Outcomes Research Institute (PCORI) is funding Cycle 3 to enhance patient-centered comparative clinical effectiveness research (CER). This initiative targets critical methodological gaps, focusing on improving the use of artificial intelligence, study design, data research networks, and ethical protections. By addressing these areas, PCORI aims to strengthen the quality of evidence in CER, thus promoting better outcomes in healthcare decision-making.

The National Cancer Institute (NCI) invites applications for the Toward Translation of Nanotechnology Cancer Interventions (TTNCI) program. This funding opportunity focuses on advanced pre-clinical research aimed at developing nanotechnology-based cancer diagnostics and therapeutics. TTNCI awards will support the maturation of innovative nanomedicines using nanoparticles and nano-devices, enhancing cancer treatment efficacy. Successful projects will progress towards further NCI translational programs, such as the NExT initiative.

Excellence in Medicine Awards

The AMA Foundation’s Excellence in Medicine Awards honor physicians and medical advocates who exemplify the highest values of the profession—volunteerism, community engagement, leadership, and service to underserved populations. Each recipient is recognized at a ceremony during the AMA Annual Meeting in Chicago and receives a $2,500 grant honorarium directed to a nonprofit health organization of their choice. Since 2005, more than 100 honorees have been celebrated through this program, with over $250,000 awarded to strengthen community health and advance equitable care nationwide. 

Excellence in Medicine Awards- Dr. Debasish Mridha Spirit of Medicine Award

Recognizes the work of U.S. physicians who demonstrate altruism, compassion, integrity, leadership and personal sacrifice while providing quality health care to destitute, distressed or marginalized populations in impoverished communities.

Made possible by Debasish Mridha, MD

Better World Scholarship Fund

The scholarship encourages women to acquire a degree in a science, technology, engineering, or math (STEM) field. The donor’s bachelor’s degree is in mathematics, followed 15 years later with a master’s degree in business administration. Her degree in mathematics provided opportunities for jobs in software development and application, medical research, technical documentation, organizational education and training, scientific research, and business. Her career was challenging, dynamic, encouraged creativity, never boring, offered schedule flexibility that allowed her to parent her four children, provided career choice independence, and was lucrative. Go STEM Girls!

Award Amount:

• Minimum $1,000

The Robert P. Wadell Transportation Engineering Scholarship, established in 2022 by Robert P. Wadell, P.E., MSCE, F.ASCE, supports undergraduate students in civil engineering with a focus on transportation. Funded through the ASCE Foundation, the scholarship aims to aid up to two deserving students annually with tuition and fees. Eligible applicants must be U.S. citizens enrolled in an ABET-accredited program and members of the ASCE. Preference is given to those in their final two years of study.

The Dairy Health, Efficiency & Resource Dynamics Initiative Grant seeks innovative research proposals to enhance animal health, economic viability, and environmental outcomes in the U.S. dairy industry. A partnership between FFAR, Dairy Management Inc., and Zoetis, this initiative aims to explore the interconnections between dairy health, welfare, economics, and environmental sustainability, addressing critical gaps in understanding the impacts of improved animal health on dairy production.

Excellence in Medicine Awards

The AMA Foundation’s Excellence in Medicine Awards honor physicians and medical advocates who exemplify the highest values of the profession—volunteerism, community engagement, leadership, and service to underserved populations. Each recipient is recognized at a ceremony during the AMA Annual Meeting in Chicago and receives a $2,500 grant honorarium directed to a nonprofit health organization of their choice. Since 2005, more than 100 honorees have been celebrated through this program, with over $250,000 awarded to strengthen community health and advance equitable care nationwide. 

Excellence in Medicine Awards- Dr. Edmond and Rima Cabbabe Dedication to the Profession Award

Honors physicians who are committed to expanding knowledge through teaching, conducting research and publishing. Other qualifying virtues include leadership, volunteerism and philanthropic activities in medical and other civic organizations.

Made possible by Edmond Cabbabe, MD, and Rima Cabbabe

The GoodRx Helps Community Catalyst Grants support community-led nonprofits dedicated to enhancing health and well-being for under-resourced groups. This funding aims to improve healthcare access, education, and essential services, addressing systemic barriers faced by these communities. Eligible organizations must demonstrate a commitment to community empowerment and possess a minimum annual operating budget of $250K. This initiative underscores the importance of fostering sustainable health improvements through targeted, inclusive support.

This FOA is intended for proposals related to basic and applied research in the STEM categories, and not related to the development of a specific system or hardware procurement.The proposal submission process has two stages:I. Applicants are encouraged to submit a white paper first to Grants@NPS.edu, ; andII. Applicants must submit a full proposal through Grants.gov (do not submit white papers through Grants.gov, only full proposals)Applicants are encouraged to submit a White Paper in advance of a Full Proposal to minimize the labor and other costs associated with the production of detailed full proposals that have little chance of being selected for funding. Based on an assessment of the white papers, the responsible Research Program Officer will provide informal feedback notification to the prospective awardees to encourage or discourage submission proposals. The Research Program Officer may also, on occasion, provide feedback encouraging re-work to strengthen a proposal. White Papers may be submitted at any time during the open period of this FOA. A separate White Paper is required for each research proposal.

The John K. Fairbank Prize in East Asian History, awarded by the American Historical Association, recognizes exceptional scholarly work in the history of East Asia, particularly focusing on books published after 1800. Eligible works must demonstrate high literary merit and can be nominated by authors or publishers. The prize aims to highlight significant contributions to the historical disciplines, with recipients announced in October 2025 and honored at the January 2026 AHA annual meeting in Chicago.

The Robert B. B. and Josephine N. Moorman Scholarship, established in 2008 by the American Society of Civil Engineers (ASCE), provides financial support for undergraduate students pursuing degrees in civil engineering or related fields. This scholarship honors Robert B.B. Moorman, a dedicated civil engineering professor. Eligible applicants must be enrolled in an ABET-accredited program and maintain good standing with ASCE. This award aims to alleviate tuition costs for deserving students committed to the civil engineering profession.

The ACS-Hach High School Chemistry Classroom Grant aims to enhance chemistry education by providing funding for innovative teaching ideas. Since its inception in 2008, over 700 teachers have benefited from grants of up to $1,800. Eligible applicants are U.S. high school chemistry educators, and the funding can be used for laboratory supplies, instructional materials, professional development, and student-led field studies, fostering a deeper understanding of chemistry.

The Garden Club of Houston, established in 1924, promotes gardening and environmental conservation through various community initiatives. Their funding supports nonprofit organizations and government entities, focusing on projects that enhance public landscapes, educational resources, and community gardens. Grants are not awarded for operating funds or endowments, with preference given to projects within the greater Houston area. This commitment to civic improvement underscores their mission to foster a love of gardening and environmental stewardship.

The Congressional Science Fellowship Program offers a unique opportunity for Ph.D. holders to work at the intersection of science and government in Washington D.C. This prestigious fellowship, sponsored by ASA, CSSA, and SSSA, allows participants to apply their expertise as special assistants to Congress members. The fellowship begins in September 2025 and concludes in August 2026, providing an annual stipend and relocation expenses. Ideal for early to mid-career scientists, it encourages the use of scientific knowledge in public policy.

The Community Foundation of Shelby County

Our Mission

To inspire donor generosity and transform it into meaningful, lasting impact through charitable gifts.

Our Vision

To be the primary partner for donors who want to advance the community’s quality of life and capacity for excellence.

Ginny and Jim Thompson Scholarship

Selection based upon (in order of priority):

Financial need, academic ability, recommendations, and an essay, “Why is education important to me?”

Awards

• One $1,000 scholarship

The Edward C. Roy Jr. Award for Excellence in K-8 Earth Science Teaching, established by the American Geosciences Institute, honors educators who demonstrate exceptional leadership in earth science education. This prestigious award includes a $2500 prize for the winning teacher and a $1500 grant to attend the National Science Teaching Association's annual conference. The award celebrates the legacy of Dr. Edward C. Roy Jr., promoting innovation and excellence in teaching for future generations.

The OpenAI A People-First AI Fund supports U.S.-based nonprofits with 501(c)(3) status, focusing on AI literacy, community innovation, and economic opportunity. It aims to enhance public understanding of AI, promote participatory design in AI applications by communities, and expand access to meaningful work through inclusive practices. Organizations at all stages of AI adoption are encouraged to apply, especially those addressing the needs of traditionally marginalized populations. This initiative emphasizes equitable distribution of AI benefits.

NRA Range Grant Program

General Provisions

The following guidelines govern the award of all grants made under the auspices of the NRA Range Grant Program. Please read this entire document prior to completing a grant application. The NRA Range Grant Program was established in September 2000 by a resolution of the NRA Board of Directors. This resolution also dissolved a separate account established by the Board of Directors known as the Range Loan Fund. A portion of the endowment's earnings are used to award grants for purposes consistent with the endowment's objectives. The amount distributed annually is limited to the lesser of the endowment's prior year's net earnings or 5% of the endowment's fair value as of December 31 of the previous year. Range Grant funds are made available at the NRA's sole discretion to qualifying NRA-affiliated clubs and associations by approval of the Range Development Committee - a standing committee of the NRA Board of Directors.

AmeriCorps Vista

AmeriCorps is the federal agency that improves lives, strengthens communities, and fosters civic engagement through service and volunteering. AmeriCorps brings people together to tackle the country’s most pressing challenges through national service and volunteerism. AmeriCorps members and AmeriCorps Seniors volunteers serve with organizations dedicated to the improvement of communities and those serving. AmeriCorps helps make service a cornerstone of our national culture.

Founded in 1965, AmeriCorps VISTA is a federal anti-poverty national service program designed to provide resources to nonprofit organizations and public agencies to strengthen efforts to address poverty and poverty-related problems in the United States. In 1993, VISTA was incorporated into the AmeriCorps network of national service programs administered by the Corporation for National and Community Service, now known as AmeriCorps.

AmeriCorps VISTA Request for Concept Paper

Projects must be developed in accordance with AmeriCorps VISTA core principles:

• an anti-poverty focus
• community empowerment
• sustainable solutions
• capacity building

Project applications must address one of the following areas:

• Economic Opportunity
• Healthy Futures
• Education
• Veteran and Military Families

The Civic Experiment Grant by the Trust for Civic Life supports innovative, community-driven projects aimed at enhancing civic engagement. It focuses on rural areas, empowering local leaders to tackle challenges collaboratively. Grants up to $25,000 are available for organizations that are non-partisan and primarily serve rural communities, emphasizing inclusivity and sustainable impact. The next nomination period begins in early 2026, following a closed cycle for 2025. This initiative fosters long-term civic infrastructure and community resilience.

The Diana and Leon Feffer Scholarship Fund, administered by the Community Foundation of Western Massachusetts, provides financial support to residents of Franklin, Hampden, and Hampshire Counties. Eligible students include undergraduates and graduates attending accredited institutions in the U.S. Students can receive up to $3,000, which may affect financial aid. Scholarships can cover tuition and other educational costs, and recipients should confirm tax implications with their colleges or tax advisors.

American Physical Society

The American Physical Society is a nonprofit membership organization working to advance physics by fostering a vibrant, inclusive, and global community dedicated to science and society. APS represents more than 50,000 members, including physicists in academia, national laboratories, and industry in the United States and around the world.

APS Honors recognizes and celebrates the accomplishments of the global physics community. Guided by our core values, APS Honors encourages nominations that reflect the full range of talent, distinction, and experience in our field, and supports broad canvassing for professional achievement across diverse backgrounds, perspectives, and expertise.

Joseph A. Burton Forum Award

The Joseph A. Burton Forum Award recognizes outstanding contributions to the public understanding or resolution of issues involving the interface of physics and society. The award consists of $5,000, a certificate citing the contributions of the recipient, and an allowance for travel to the meeting of the Society at which the award is presented. It will be awarded annually.

Nominations will be considered for three review cycles provided the nominator re-certifies the nomination before the next deadline.

The Paul Purcell "Kids Win!" Annual Baird Education Grant honors the legacy of former Baird CEO Paul E. Purcell, who dedicated his life to educational causes. Established in 2020, this grant supports 501(c)(3) organizations that ensure all children, regardless of circumstances, have access to quality education. Funded by Baird and its associates, it prioritizes programs serving diverse and underserved populations, embodying Purcell's belief that every child deserves the opportunity to succeed.

The Lenora Jane Perdue Scholarship, offered by the North East Community Foundation, supports graduating seniors from Westfield Academy, Ripley Central School, and North East High School pursuing a degree in education. Applicants must maintain a GPA of 3.0 or higher. This scholarship aims to encourage and assist students dedicated to a career in teaching, fostering the next generation of educators in their community.

Native Forward awards are allocated based on the financial aid information provided by the institution’s Financial Aid Office. Awards can vary, ranging from $100 to $30,000 per academic year.

Native Forward Scholars Fund members of federally and state-recognized Tribes as well as first and second-generation descendants. However, Native Forward Scholars Fund scholarship opportunities have different Tribal eligibility requirements and can be determined by submitting a Tribal Eligibility Certificate.

Jeanette Elmer Scholarship

This opportunity is provided to honor the life and legacy of Jeanette Elmer.

The purpose of the Jeanette Elmer Scholarship program is to provide financial assistance to eligible American Indian and Alaska Native graduate students pursuing degrees full-time at an accredited institution in library science.

This opportunity is a need-based award.