Best Quality of Life Grants in Northern Mariana Islands

This NOFO invites applications for innovative research aimed at developing and implementing interventions to prevent and treat substance use disorders (SUDs) and overdose. It encourages studies that can rapidly advance candidate solutions towards regulatory approval or clinical use, while also addressing co-morbid SUDs. The initiative supports a wide range of research including basic, clinical, translational, and implementation strategies to tackle drug misuse and related health issues, such as HIV/AIDS.

The NIDA Research Education Program (R25) aims to enhance the training of a workforce skilled in biomedical, behavioral, and clinical research, particularly regarding substance use disorders. This program supports educational activities that prepare clinicians and clinical researchers. Applications are due by 5:00 PM local time, with optional Letters of Intent encouraged 30 days prior to the full proposal deadline. This initiative does not fund non-research-related clinical training.

The Rapid Response Opioid and Pain Management ECHO Funding Opportunity by the Association of State and Territorial Health Officials (ASTHO) aims to enhance clinician training in effective pain management strategies. This initiative focuses on non-opioid treatments, substance use screening, and risk reduction counseling, promoting compassionate care while addressing public health challenges and ensuring continuity for patients affected by prescription disruptions. The program seeks to improve overall health outcomes and reduce risks associated with opioid use.

The Desalination and Water Purification Research Program, led by the Bureau of Reclamation, aims to enhance water supply through innovative research in water treatment technologies. This initiative seeks proposals for laboratory and pilot-scale projects that demonstrate significant benefits and commercialization pathways. By addressing cost and energy barriers, the program aligns with federal priorities to improve resource management and support the development of sustainable water solutions for the American public.

This funding opportunity encourages applications for clinical observational studies focused on musculoskeletal, rheumatic, and skin diseases. It aims to gather essential data for designing future clinical studies, enhancing understanding of disease symptoms, progression, and patient outcomes. Observational studies supported by this initiative will contribute to the development of objective biomarkers and effective outcome measures. Applicants are invited to address key challenges in clinical project design, ensuring a robust foundation for subsequent clinical trials.

The Title XVI Water Reclamation and Reuse Projects, funded by the US Department of the Interior's Bureau of Reclamation, invites proposals for innovative water reuse solutions. This program enhances water supply reliability and supports sustainable practices for urban and agricultural communities. By leveraging Federal and non-Federal resources, the initiative aims to address water scarcity and improve hydropower reliability, aligning with national priorities for energy and resource management.

The National Estuarine Research Reserve System (NERRS) Land Acquisition and Construction Program for Fiscal Year 2026, funded by NOAA, aims to enhance research and education by supporting land acquisition and construction projects. With approximately $8.5 million available, the program prioritizes strategic expansions of Reserve boundaries and facility enhancements, ensuring sustainable design standards. Funding will support 5-20 projects over 12-36 months, with potential extensions for complex projects, contingent on available funds and negotiations.

The Jobs Plus NOFO for FY2026, issued by the US HUD's Office of Public and Indian Housing, aims to enhance job opportunities for public housing residents. This initiative encourages innovative programs that prepare individuals for employment in high-demand fields, ultimately fostering economic stability within communities. By focusing on workforce development, this funding opportunity seeks to empower residents through education and training, paving the way for long-term success and self-sufficiency.

The USDA Forest Service's Invasive Species Program funding opportunity invites proposals aimed at enhancing invasive species prevention. By leveraging existing research and knowledge, projects can create actionable solutions to protect American agriculture. This initiative seeks to connect scientific insights with practical regulatory improvements, thereby reducing the introduction and establishment of new invasive pests. Previous research, including horizon scanning and monitoring sentinel trees, serves as a foundation for developing effective strategies.

The NIAAA Integrative Neuroscience Initiative on Alcoholism (INIA) aims to renew support for two research consortia focusing on the biological mechanisms of excessive alcohol consumption and Alcohol Use Disorder (AUD). By utilizing advanced technologies and fostering collaboration across multiple sites, this initiative seeks to standardize neurofunctional measures and enhance reproducibility in findings. Investigators are encouraged to prepare for future applications to this NOFO, which will utilize the U24 activity code.

The Affirm Cares Employee Foundation Grant, established by Affirm, aims to support non-profit organizations making a significant impact in financial literacy, community enrichment, and technology education. Grants range from $1,000 to $10,000, focusing on sustainable initiatives that empower communities and alleviate housing insecurity. Eligible applicants must be 501(c)(3) designated non-profits operating within the U.S. The foundation prioritizes measurable outcomes in its funding efforts, fostering civic engagement and vibrant communities.

The Exploratory Clinical Trial Grants in Arthritis and Musculoskeletal and Skin Diseases (R61 Clinical Trial Required) aim to support clinical trials that can be completed within a limited timeframe. This funding opportunity encourages a variety of exploratory studies that align with the NIAMS mission, focusing on interventions such as drugs, biologics, devices, and various therapies. Applications are due by 5:00 PM local time of the applicant organization.

The FY26 Bureau of Land Management Forest and Woodlands Resource Management program aims to enhance forest health and promote sustainable management practices. It supports initiatives under Executive Order 14225 and The One Big Beautiful Bill, focusing on fire resiliency, habitat conservation, and recovery from pests and diseases. Activities may include tree planting, thinning, and vegetation control, alongside necessary planning and analysis for compliance with environmental regulations.

The NIDA Mentored Clinical Scientist Development Program Award aims to foster research independence in clinician scientists by providing intensive supervised research training and career development in the field of substance use and substance use disorder. Applications are due by 5:00 PM local time of the applicant organization, ensuring timely submission for this essential funding opportunity.

The Maine Cancer Foundation is seeking proposals for cancer screening initiatives aimed at early detection and prevention. This RFP focuses on screenings for breast, cervical, colorectal, lung, prostate, and skin cancers. Proposals should align with evidence-based practices endorsed by the CDC and U.S. Preventive Services Task Force. Interested applicants are encouraged to consult with MCF prior to submission to discuss project concepts and receive feedback on draft applications.

The FY26 Bureau of Land Management Invasive and Noxious Plant Management program focuses on preventing and controlling invasive species that threaten public lands and native plant communities. These invasive plants impose significant economic burdens and disrupt ecosystems. The program aims to enhance detection, rapid response, and education on invasive species, while also promoting rehabilitation efforts and biological control to protect valuable resources on public lands.

The HEAL Initiative: Pain Research Enhancement Program (PREP) supports R15-eligible Principal Investigators in conducting innovative pain research. This program encourages interdisciplinary partnerships and aims to enhance the research environment for health professional trainees. Key application deadlines include November 19, 2024, and October 28, 2025, with specific dates for AIDS-related applications. By fostering collaboration, the initiative seeks to advance understanding and treatment of pain.

The U.S. Fish and Wildlife Service's Coastal Program offers vital technical and financial support for projects aimed at protecting and restoring fish and wildlife habitats in priority coastal ecosystems. Collaborating with conservation partners, the program ensures that all projects are scientifically sound and align with the missions of the Department of the Interior. Applicants must contact a local office for guidance before applying, ensuring projects meet strategic conservation goals.

The Applied Drug Policy Research Experiences project aims to provide graduate students and recent post-graduates with hands-on research opportunities to support the National Drug Control Strategy. Through rigorous studies and data analyses, this initiative will explore the evolving dynamics of illicit drug supply and usage, assisting public health and safety officials in anticipating drug-related issues and crafting effective responses to safeguard the American public.

The NIAID Career Transition Award (K22) supports postdoctoral fellows transitioning to independent research positions, fostering their development into successful biomedical scientists. Key deadlines for applications span from February 2025 to June 2027, including specific dates for standard, renewal, and AIDS-related grants. This initiative, funded by the NIH, aims to enhance the career trajectory of emerging researchers in clinical and biomedical fields, ensuring a robust pipeline of innovative scientific talent.

The WKKF Grant, offered by the W.K. Kellogg Foundation, is dedicated to fostering a future where every child and family thrives. With a focus on nurturing early education, accessible healthcare, and equitable food systems, this grant supports initiatives that empower communities across the U.S. and parts of Mexico and Haiti. Organizations meeting IRS regulations and being legal entities, particularly 501(c)(3) nonprofits, are encouraged to apply for funding to create lasting impacts in their communities.

The Drug-Free Communities (DFC) Support Program aims to foster collaboration among community coalitions to combat youth substance use. Established by the Drug-Free Communities Act of 1997, it encourages partnerships among various stakeholders, including governmental and non-profit agencies. The program focuses on reducing substance use among youth and promoting protective factors within communities. This funding opportunity is available for those who have completed the initial funding cycle or experienced funding interruptions, supporting their ongoing efforts to create a healthier environment for youth.

The Drug-Free Communities (DFC) Support Program, initiated by the Drug-Free Communities Act of 1997, aims to bolster community coalitions dedicated to preventing youth substance use. Funded by the US HHS's Substance Abuse and Mental Health Services Administration (SAMHSA), this program focuses on collaboration among various stakeholders, including government and non-profit entities, to effectively reduce substance abuse among youth and promote protective factors within communities.

The National Institute on Drug Abuse (NIDA) is launching a specialized entrepreneurship program aimed at life science researchers in the field of substance use disorders (SUD). This initiative will equip researchers with essential skills to transform their innovative ideas into viable products, focusing on aspects such as market evaluation, customer discovery, and intellectual property. The course will be delivered in a hybrid format to engage US-based SUD researchers effectively, fostering collaboration and advancing the field.

Lilly Foundation

To extend Lilly’s charitable reach and impact, the Eli Lilly and Company Foundation (Lilly Foundation) was established in 1968 and is supported by donations from Eli Lilly and Company.

The Foundation is a tax-exempt, private foundation supporting programs that align with its philanthropic priorities.

Grantmaking Approach

The Lilly Foundation’s work is guided by a charitable vision of a world where every person has an opportunity to live their healthiest life. Through grantmaking focused on Lilly Foundation’s charitable vision, grants can serve as a catalyst for closing gaps and empowering individuals and communities to thrive.

All proposals should demonstrate clear alignment with at least one focus area and include charitable outcomes that are measurable and consistent with the Foundation’s long-term charitable goals.

Global Health, K-12 STEM Education and Economic Mobility Grant

Focus Areas

Global Health

Lilly Foundation, through its charitable grants, aims to support permissible charitable efforts to improve access to quality healthcare for resource-limited communities in low- and lower-middleincome countries (L/LMICs) and in the United States. Strengthening access to care is essential for enhancing community well-being and supporting economic stability in resource-limited settings.

The Global Health focus area aims to close gaps in quality healthcare by supporting charitable solutions that improve access, bring care closer to where people live, and address the high burden of non-communicable diseases (NCDs) in resource-limited settings. To the extent permissible, the Foundation prioritizes charitable efforts related to cardiometabolic health in resource-limited settings.

K-12 STEM Education

The K-12 STEM Education focus area aims to close the gaps for students from low-income communities by supporting programs that foster new pathways and pipelines to STEM education through focused K-12 efforts, concentrating on the critical middle school years. The Foundation’s K-12 STEM Education grants are focused on initiatives that benefit Marion County, Indiana.

Economic Mobility

The Economic Mobility focus area supports charitable and educational programs that strengthen workforce readiness, postsecondary and skills-based educational pathways, and housing stability to promote long-term prosperity. This support is focused on Marion County, Indiana, with the goal of improving economic opportunity for low-income communities and advancing community well-being.

The Looking Out Foundation Grant supports social justice and humanitarian initiatives, having donated nearly $6 million to various causes globally. With an average donation of $25 per campaign, it aids organizations focused on disaster relief, racial justice, and support for marginalized communities. Eligible applicants must be tax-exempt public charities under Section 501(c)(3). The foundation prioritizes diverse funding sources and encourages organizations to adapt to changing needs, with grant allocations ranging from $5,000 to $25,000.

The WaterSMART Applied Science Grants aim to enhance water management and supply reliability through innovative research and data utilization. By inviting qualified entities to apply for funding, the program focuses on improving hydrologic data access, forecasting capabilities, and modeling tools. This initiative aligns with federal priorities to optimize resources, ensuring water managers can effectively address future demands and adapt to climate challenges, thus fostering resilience in water operations across the nation.