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Best Large Grants for Nonprofit Organizations in Oklahoma

Find the perfect Large Grants for Nonprofit Organizations in Oklahoma on Instrumentl. 9,000+ Large Grants for Nonprofit Organizations in Oklahoma in the United States.

9,000+

Available grants

$2.67B

Total funding

$5K

Median grant

9,000+ grants
$2.67B total
$5K median

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9,289 Results based on applied filters

Melanoma: Established Investigator Award

Melanoma Research Foundation
Private
United States
Up to US $125,000
The Melanoma Established Investigator Award offers up to $125,000 annually for two years, aimed at established melanoma researchers or senior researchers transitioning into melanoma research. Eligible applicants include Associate Professors or higher, with both tenured and non-tenured faculty encouraged to apply. U.S. citizenship is not a requirement for this funding opportunity provided by the Melanoma Research Foundation.
Cancer / Oncology Pediatric Cancers Skin Diseases & Dermatology

Demonstration Projects for Whole-Person Health Models for Women Living with HIV in the South

Dept. of Health & Human Services: Centers for Disease Control & Prevention
Federal Government
American Samoa, Guam +7 more
Unspecified amount
This project aims to enhance health outcomes for women living with HIV in the South by integrating HIV care with comprehensive women's health services through coordinated Clinic and Community Collaboratives. By funding organizations to implement targeted strategies such as culturally responsive services and learning collaboratives, the initiative seeks to improve access to essential health services, increase the number of women initiating rapid ART, and foster sustainable healthcare models that address the unique needs of this population.
HIV / AIDS

Fruit of the Vine Scholarship

Napa Valley Community Foundation
Private
United States
US $2,000 - US $4,000

Napa Valley Community Foundation

There are more than 800 Community Foundations in the US, each devoted to a specific region. We operate independently, with a common goal in mind: to be a platform for local people who want to pay it forward. To deliver resources to effective charitable programs. And to make our communities stronger and more successful by doing these two things.

Among our peers, Napa Valley Community Foundation ranks first on several key measures of donor satisfaction and impact, according to a recent donor survey conducted by the Center for Effective Philanthropy. Our donors say that we deeply understand their interests, and deeply understand the needs of Napa Valley. That, in a nutshell, is our job.

Fruit of the Vine Scholarship

The Fruit of the Vine Scholarship Fund benefits graduating Napa County high school seniors and Napa Valley College transfer students who will find the cost of higher education a financial hardship. Consideration is given to applicants who are the first in their family to attend college or are employed (or have a parent or guardian who is employed) in the Napa County wine or grape industry. Recipients of the scholarship will receive funding for up to four years of undergraduate study.

Education - Higher Education Viticulture Academic Scholarship Programs +1 more

MRF Breakthrough Consortium (MRFBC) Young Investigator Team Award to Advance the Field of Translational Immuno-Oncology

Melanoma Research Foundation
Private
United States
Up to US $150,000
The MRFBC Young Investigator Team Award supports innovative research in immuno-oncology for melanoma, offering up to $150,000 annually for two years. This funding targets U.S.-based researchers aiming to enhance clinical outcomes for melanoma patients or deepen the scientific understanding of immuno-oncology. The MRF collaborates with key institutions to address challenges in melanoma research, fostering partnerships that maximize research potential and impact.
Cancer / Oncology Skin Diseases & Dermatology Pediatric Cancers

Scaling Pathways to Homeownership

Capital One Foundation
Corporate
American Samoa, Guam +4 more
US $200,000
  • Innovative: An approach that brings fresh thinking, tools, or models to homeownership in ways that challenge the status quo and demonstrate a disruptive, future-oriented vision with potential to inspire or shift broader field practice.
  • Impactful: A solution with meaningful potential to expand homeownership through knowledge and action, featuring clear and measurable progress indicators that demonstrate capacity to shift trajectories for low- and moderate-income households.
  • Bridge-Building: An initiative that effectively connects and unifies a wide range of stakeholders, fostering meaningful collaboration across sectors or perspectives. The strongest submissions will reflect strong community partnerships across the housing ecosystem.
  • Durable: A sustainable pathway that addresses root causes of homeownership barriers rather than just symptoms, with compelling evidence of potential to elicit robust support from broad private, philanthropic, and public funding sources over time.
Homeownership Equitable & Affordable Housing

NIAID SBIR Phase II Clinical Trial Implementation Cooperative Agreement (U44 Clinical Trial Required) (352061)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
United States
Up to US $3,600,000
The NIAID SBIR Phase II Clinical Trial Implementation Cooperative Agreement (U44) invites small businesses to submit applications for investigator-initiated clinical trials. This program particularly supports high-risk, hypothesis-driven studies that may involve non-routine interventions or unlicensed products. Letters of Intent are encouraged and due 30 days prior to the full proposal deadline. All applications must be submitted by 5:00 PM local time of the applicant organization.
Allergies & Allergic Diseases Infectious & Parasitic Diseases Immune System Diseases

Alliance for Innovation on Maternal Health (AIM) Capacity Program

Health Resources and Services Administration
Federal Government
American Samoa, Guam +4 more
Up to US $230,000
The Alliance for Innovation on Maternal Health (AIM) Capacity Program aims to enhance the capacity of state, territorial, and Tribal entities in the U.S. to implement and sustain AIM Patient Safety Bundles. By promoting evidence-based maternal safety practices, the program strives to improve the quality of maternity care, enhance maternal health outcomes, and significantly reduce preventable maternal mortality and severe morbidity.
Maternal And Perinatal Health Patient Safety

Ryan White HIV/AIDS Program Part D - Women, Infants, Children and Youth Grant Supplemental Funding (363415)

US HHS: Health Resources & Services Administration (HRSA)
Federal Government
American Samoa, Guam +4 more
Up to US $200,000
The Ryan White HIV/AIDS Program Part D provides supplemental funding aimed at enhancing the infrastructure and capacity of organizations to deliver high-quality, family-centered HIV care services. This initiative focuses on two key areas: HIV Care Innovation and Infrastructure Development, ensuring improved access to essential services for women, infants, children, and youth affected by HIV.
HIV / AIDS

Ryan White HIV/AIDS Program Part B AIDS Drug Assistance Program Training and Technical Assistance

US HHS: Health Resources & Services Administration (HRSA)
Federal Government
American Samoa, Guam +4 more
Up to US $750,000
The Ryan White HIV/AIDS Program Part B AIDS Drug Assistance Program Training and Technical Assistance aims to enhance the capacity of ADAPs. By providing essential tools and expert guidance, the program seeks to improve health outcomes for individuals living with HIV in an evolving healthcare landscape. This initiative is funded by the US HHS through the Health Resources & Services Administration, ensuring support and resources are effectively allocated to meet the needs of vulnerable populations.
HIV / AIDS

Troutville Volunteer Fire Department Scholarship Fund

Community Foundation Serving Western Virginia
Private
United States
Approximately US $1,000

Troutville Volunteer Fire Department Scholarship Fund

Fund provides higher educational scholarship assistance to deserving students.

Amount

  • $1,000+
  • non-renewable
Education - Higher Education Emergency Medical Care & Services Career / College Preparation +2 more

NIAMS Clinical Trial Implementation Cooperative Agreement (UG3/UH3 Clinical Trial Required)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Up to US $250,000
The NIAMS Clinical Trial Implementation Cooperative Agreement (UG3/UH3) invites applications for the execution of investigator-initiated, interventional clinical trials across various phases. This program supports researchers in finalizing preparations necessary for trial initiation, including IRB establishment and staffing. Successful UG3 projects may transition to the UH3 phase, emphasizing the need for hypothesis-driven studies with significant clinical impact within NIAMS's research mission.
Skin Diseases & Dermatology Arthritis Musculoskeletal Diseases

Faculty Innovation in Education Award

American Board Of Psychiatry and Neurology, Inc.
Private
United States
Up to US $120,000
The ABPN Faculty Innovation in Education Award aims to support innovative educational projects that enhance residency training and lifelong learning for psychiatrists and neurologists. With a funding potential of $120,000 over two years, the award prioritizes projects focused on Diversity, Equity, and Inclusion, clinical skills evaluations, and professional competence. Applicants must hold a faculty position at an accredited U.S. medical school or submit a validated offer letter. Preference is given to first-time applicants and those at junior or mid-faculty levels.
Neuroscience Neurological Diseases & Disorders Mental Health & Psychiatric Diseases +2 more

ConocoPhillips Charitable Investments: Local Community Giving

ConocoPhillips
Corporate
Anchorage Municipality, Alaska, Australia +7 more
Unspecified amount
ConocoPhillips Charitable Investments focuses on local community giving, emphasizing collaborative problem-solving to address unique community needs. Eligible organizations include 501(c) charities, political subdivisions, and accredited schools. Ineligible entities include those promoting religious worship or political advocacy. Recent funding has supported education and social services, particularly in the Permian region, reflecting ConocoPhillips' commitment to responsible citizenship and community enhancement through targeted charitable investments.
Education Health & Medicine Community / Public Safety +5 more

Mentored Career Development Award to Promote Faculty Diversity in Biomedical Research (K01 Independent Clinical Trial Required)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Up to US $130,000
The Mentored Career Development Award (K01) from the NIH aims to diversify the biomedical research workforce by supporting candidates from underrepresented backgrounds. It provides mentoring and training in research independence, focusing on cardiovascular, pulmonary, hematologic diseases, and sleep disorders. Eligible institutions can guide faculty members in special studies, but applicants should not lead their own clinical trials. This initiative promotes diversity and enhances research capability in health disparities populations.
Cardiovascular Diseases & Systems Hematological Systems Respiratory Diseases & Systems +2 more

Joest, Brian H. Memorial Scholarship

Noble County Community Foundation
Private
United States
US $1,000

About Us

Driving Positive Change in Noble County!

At the Community Foundation of Noble County we are passionate about making Noble County an even better place to call home. Since 1991, area residents have been turning to the Community Foundation of Noble County to make their philanthropic giving as effective as possible, as we see it as our mission to serve as a catalyst for positive change. The Community Foundation of Noble County is a public charity 501 (c) 3 entity.

As a group of invested community members, we identify local current and emerging issues and stimulate resources to address those needs, helping our region prepare for the future. We then leverage gifts and bequests from generous donors like you to drive positive change through grants in such areas as arts and culture, education, health and human services, civic affairs and other charitable areas of interest.

Our Mission

To improve the quality of life in Noble County by serving as catalyst for positive change, enabling donors to carry out charitable intent, and making grants.

Donor Story – Joest, Brian H. Memorial Fund

Brian Henry Joest was born in Lagrange, Indiana in 1957. He grew up on the Atwood family farm that was settled by his ancestors in the mid-1800s. Now a historical Hoosier Homestead, the Atwood Farm provided him with all the outdoor activities possible for a farm boy in northern Indiana. Brian’s love of nature and the outdoors continued throughout his life. After high school, he attended Glen Oaks Community College and then Purdue University, where he earned a Bachelor of Science degree in Agricultural Economics

For decades, Brian went on annual backcountry camping and canoeing trips across the US and Canada. He paddled some of the most beautiful rivers in North America. He took a road trip to remote northern Alaska. He camped out on an active volcano in Guatemala. He explored most of the US National Parks. In his later years, his travels were less rustic but still adventurous as he and his wife, Cindy, checked off many items on his bucket list. They traveled to Paris, Rome, Florence, the Amalfi Coast of Italy, Ireland, and all around the US and Canada.

Brian began his professional career with management positions at Many Glacier Hotel at Glacier National Park in Montana; the Grand Hotel on Mackinac Island, Michigan; the Mountain View Grand Resort in New Hampshire; and Copper Mountain Ski Resort in Colorado. He also worked for Marriott Corporation where he opened new hotels across the Midwest.

Upon the birth of his first child, Brian moved his young family back to Lagrange County so his children could grow up on the Atwood Farm near their family. Brian worked for Life Care Center of Lagrange, was a substitute teacher for the Lakeland School District, and worked for fifteen years for East Noble School Corporation, most recently as an Instructional Assistant for high school students with special needs.

Brian enjoyed doing things for other people and took so much joy in their happiness. His career choices reflected his servant’s heart. He loved working in the hospitality industry and being able to make someone else’s vacation more memorable. He helped the patients and their families at Life Care Center. He spent years making a difference for students in our local schools.

Brian experienced first-hand the unique challenges faced by the families of individuals with special needs. He was a father, stepfather, and step-grandfather to children with different disabilities. He understood the difficulties of navigating support systems and knew there are gaps in these systems that result in unmet needs. At the end of his life, while he was fighting cancer, Brian dreamed of being able to return to the classroom to help special needs students. This was not to be. In 2022, his family created this fund in his honor with the intent of continuing his dream to help improve the lives of individuals with special needs.

Kinesiology & Sports Medicine Speech Rehabilitation Physical Therapy +4 more

Senator Harold “Potch” Wheeler Memorial Scholarship

Community Foundation of Whitley County
Association/Society
United States
Unspecified amount
The Senator Harold "Potch" Wheeler Memorial Scholarship, managed by the Community Foundation of Whitley County, honors the legacy of a dedicated public servant. This competitive scholarship is available annually to high school seniors from Whitley County who plan to pursue college education in public service or within the Indiana Department of Natural Resources. Recipients are chosen based on their embodiment of the ideals and character traits exemplified by Senator Wheeler.
Education - Higher Education Education - High School Academic Scholarship Programs +1 more

Mentored Quantitative Research Development Award (Parent K25 Independent Basic Experimental Studies with Humans Required) (353711)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The Mentored Quantitative Research Development Award (K25) aims to engage skilled professionals in NIH-relevant research, enhancing their expertise in addressing health-related issues. This award supports individuals with backgrounds in quantitative sciences and engineering, providing them with dedicated time for supervised research and study. Key application deadlines span from June 2024 to February 2027, emphasizing the program's commitment to fostering innovative research in health and disease.
Engineering Mathematics Chemistry +8 more

Friends Foundation for the Aging Grant

Friends Foundation for the Aging
Private
United States
Unspecified amount
The Friends Foundation for the Aging Grant supports innovative and impactful programs aimed at addressing the needs of older adults, particularly within underserved populations. This Quaker foundation prioritizes collaboration and sustainability in its funding efforts. Eligible applicants must be 501(c)(3) public charities focused on enhancing the quality of life for aging individuals. Grants are typically awarded for one year and target organizations that align with the foundation's mission and values.
Aging / Gerontology Senior Services Protestantism +1 more

Ryan White HIV/AIDS Program (RWHAP) Integrated HIV/AIDS Planning Resource Allocation Cooperative Agreement

US HHS: Health Resources & Services Administration (HRSA)
Federal Government
American Samoa, Guam +4 more
Up to US $700,000
The Ryan White HIV/AIDS Program (RWHAP) Integrated HIV/AIDS Planning Resource Allocation Cooperative Agreement aims to enhance the effectiveness of HIV prevention and care planning for RWHAP Parts A and B recipients. Through the provision of training, tools, and technical assistance, this initiative seeks to optimize resource allocation and strengthen the overall system of HIV care and treatment, ultimately improving health outcomes for those affected by HIV.
HIV / AIDS

Moody’s Community Impact Grant Program

Moody’s Investors Service, Inc.
Corporate
Argentina, Brazil +21 more
Unspecified amount
The Moody's Community Impact Grant Program supports organizations with tax-exempt status to foster social and economic equality. Established by Moody's Foundation, it prioritizes initiatives that empower underestimated communities and entrepreneurs, driving innovation and ecological restoration. The foundation focuses on inclusive growth, providing resources for small businesses and community resilience. Eligible organizations must be registered charities under U.S. IRS guidelines, while ineligible entities include individuals and those promoting unlawful discrimination.
Business Development Entrepreneurship Habitat & Ecosystem Restoration

AIDS Drug Assistance Program (ADAP) Emergency Relief Funds (ERF) (363159)

US HHS: Health Resources & Services Administration (HRSA)
Federal Government
American Samoa, Guam +4 more
Up to US $10,000,000
The AIDS Drug Assistance Program (ADAP) Emergency Relief Funds aim to provide essential funding to states and territories. This initiative focuses on preventing, reducing, or eliminating waiting lists for ADAP services, ensuring timely access to necessary medications and support for individuals living with HIV/AIDS. This program addresses critical funding shortfalls, enhancing the healthcare infrastructure and improving health outcomes in affected communities.
HIV / AIDS

Ryan White HIV/AIDS Program Part C Capacity Development Program (363166)

US HHS: Health Resources & Services Administration (HRSA)
Federal Government
American Samoa, Guam +4 more
Up to US $150,000
The Ryan White HIV/AIDS Program Part C Capacity Development Program aims to enhance the capabilities of community-based organizations, focusing on improving health outcomes and decreasing HIV transmission. This initiative supports individuals who have not yet accessed regular HIV care, emphasizing innovative care solutions and infrastructure development to address these critical needs.
HIV / AIDS

HIV Care Grant Program - Part B States/Territories Formula and AIDS Drug Assistance Program Formula and AIDS Drug Assistance Program Supplemental Awards

US HHS: Health Resources & Services Administration (HRSA)
Federal Government
American Samoa, Guam +7 more
Unspecified amount
The HIV Care Grant Program, funded by the US HHS: Health Resources & Services Administration (HRSA), aims to enhance access to high-quality HIV care and treatment for low-income individuals. This initiative supports states and territories in developing comprehensive systems to address the needs of those living with HIV. By providing essential resources, the program seeks to improve health outcomes and ensure that vulnerable populations receive the necessary support and services.
HIV / AIDS

Ryan White HIV/AIDS Program Part B States/Territories Supplemental Grant Program (363163)

US HHS: Health Resources & Services Administration (HRSA)
Federal Government
American Samoa, Guam +4 more
Up to US $9,000,000
The Ryan White HIV/AIDS Program Part B Supplemental Grant aims to provide essential funding to support HIV care and treatment services across states and territories. This program supplements existing formula-based funding from the RWHAP Part B and ADAP, improving access to necessary resources for those affected by HIV/AIDS. By enhancing support structures, it addresses critical healthcare needs, ensuring better health outcomes for vulnerable populations.
HIV / AIDS

National Initiatives Advancing Improvements in Care for Older Adults Grant

John A Hartford Foundation
Private
United States
Up to US $300,000

About The John A. Hartford Foundation

The John A. Hartford Foundation, based in New York City, is a private, nonpartisan, national philanthropy dedicated to improving the care of older adults. The leader in the field of aging and health, the foundation has three priority areas: creating age-friendly health systems, supporting family caregivers, and improving serious illness and end-of-life care.

Since 1982, The John A. Hartford Foundation has awarded more than $758 million in grants to enhance the health and well-being of older people.

JAHF New Partners Program Call for Proposals:

National Initiatives Advancing Improvements in Care for Older Adults

The John A. Hartford Foundation (JAHF) is entering a new chapter that builds on its work to improve care for older adults and support family caregivers while bringing new organizations, leaders and ideas into its community of grantees and partners.

Through this funding opportunity, JAHF is seeking proposals from organizations that have not previously received a major grant from the foundation.

Proposed initiatives must have a national or multi-site scope and align with at least one of the foundation's three priority areas:

  • Age-Friendly Health Systems
  • Family Caregiving
  • Serious Illness and End-of-Life Care
Senior Services Aging / Gerontology Caregiver Support / Respite Care +1 more

OREF/Musculoskeletal Transplant Foundation Research Grant Prgram

Orthopaedic Research and Education Foundation
Private
United States
US $100,000
The OREF/MTF Biologics Research Grant encourages innovative research in biologics, focusing on reconstruction, bone regeneration, and transplantation, including stem cells. It is open to licensed U.S. orthopaedic surgeons and PhD researchers with faculty appointments. The grant seeks clinically relevant projects that demonstrate practical applications and multidisciplinary collaboration, promoting excellence in research. New investigators are especially encouraged to apply, ensuring a commitment to advancing orthopaedic science.
Human Genome & Genetics Cell Biology Synthetic Biology +4 more

HIV/AIDS Clinical Trials Network Laboratory Centers

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The National Institute of Allergy and Infectious Diseases (NIAID) is launching a funding opportunity for up to four Clinical Trials Network Laboratory Centers (LCs). These LCs will support HIV prevention and treatment strategies by providing necessary laboratory infrastructure and technologies for clinical trials. They will ensure rigorous laboratory testing and oversight, enhance sample integrity, and utilize advanced data management systems to meet evolving demands in HIV research and testing.
HIV / AIDS

Large Grants for Nonprofit Organizations in Oklahoma Highlights

Looking for large grants for nonprofit organizations in Oklahoma?


Read more about each grant below or start your 14-day free trial to see all large grants for nonprofit organizations in Oklahoma recommended for your specific programs.

Last updated: October 5, 2026. Next update: November 1, 2026.

Grant Insights : Large Grants for Nonprofit Organizations in Oklahoma

Grant Availability

How common are grants in this category?

Common — grants in this category appear regularly across funding sources.

100+ Large Grants for Nonprofit Organizations in Oklahoma grants for nonprofits in the United States, from private foundations to corporations seeking to fund grants for nonprofits.

38 Large Grants for Nonprofit Organizations in Oklahoma over $25K in average grant size

22 Large Grants for Nonprofit Organizations in Oklahoma over $50K in average grant size

19 Large Grants for Nonprofit Organizations in Oklahoma supporting general operating expenses

100+ Large Grants for Nonprofit Organizations in Oklahoma supporting programs / projects

600+ Grants on Instrumentl focused on Food Access & Hunger

1,000+ Grants on Instrumentl focused on Health Care Access & Delivery

Grant Deadline Distribution

Over the past year, when are grant deadlines typically due for Large grants for Nonprofit Organizations in Oklahoma?

Most grants are due in the first quarter.

Q1
33.2%
Q2
21.5%
Q3
22.3%
Q4
23.0%

Typical Funding Amounts

What's the typical grant amount funded for Large Grants for Nonprofit Organizations in Oklahoma?

Grants are most commonly $14,375.

$500 $500 Min.
$14,375 $14.4 K Median
$567,736 $567.7 K Average
$40,331,313 $40.3 M Max.

Average Grant Size

What's the typical amount funded for Oklahoma?

Grants are most commonly $129,467.

$129,467

Total Number of Grants

What's the total number of grants in Large Grants for Nonprofit Organizations in Oklahoma year over year?

In 2024, funders in Oklahoma awarded a total of 21,444 grants.

2022 20,176

2023 20,455

2024 21,444

Top Grant Focus Areas

Among all the Large Grants for Nonprofit Organizations in Oklahoma given out in Oklahoma, the most popular focus areas that receive funding are Education, Philanthropy, Voluntarism & Grantmaking Foundations, and Human Services.

1. Education

2. Philanthropy, Voluntarism & Grantmaking Foundations

3. Human Services

Funding Over Time

How is funding for Large Grants for Nonprofit Organizations in Oklahoma changing over time?

Funding has increased by 12.02%.

2022 $2,400,280,116

2023 $2,453,750,736
2.23%

2024 $2,748,726,489
12.02%

Oklahoma Counties That Receive the Most Funding

How does grant funding vary by county?

Tulsa County, Oklahoma County, and Cleveland County receive the most funding.

County Total Grant Funding in 2024
Tulsa County $859,084,601
Oklahoma County $816,038,760
Cleveland County $278,116,338
Carter County $223,703,650
Payne County $193,389,149