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Best Operating Grants for Nonprofits in Pennsylvania

Find the perfect Operating grants for nonprofits in Pennsylvania on Instrumentl. 10,000+ Operating grants for nonprofits in Pennsylvania in the United States.

10,000+

Available grants

$2.66B

Total funding

$5K

Median grant

10,000+ grants
$2.66B total
$5K median

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AHCJ U.S. Health System Reporting Fellowship

Association of Health Care Journalists (AHCJ)
Association/Society
United States
Up to US $7,500

About

Building a community of journalists committed to better health care reporting.

We believe accurate, contextual and balanced health care reporting is more important than ever.

People depend on health care stories to make life-altering decisions every day.

AHCJ U.S. Health System Reporting Fellowship

This opportunity is for U.S.-based journalists.

Issues with the U.S. health care system are often obvious — from large swaths of uninsured residents and junk insurance plans, to high maternal mortality rates and preventable medical errors. But what is at the root of issues like these? What could an equitable health care system look like? 

Through the U.S. Health System Reporting Fellowship, supported by The Commonwealth Fund, you can pursue a significant reporting project related to the U.S. health care system at the local, regional and/or national level.

This fellowship allows mid-career journalists to maintain their regular employment while working on a major project over a 12-month calendar year. You’ll pursue the projects with the support of your newsrooms or arranged outlets, which commit to publish or air the work.

We believe that issues of health equity impact every facet of the health care system, which is why we’re specifically interested in projects focused on health equity. This might include racial disparities within a community, gaps in public health inclusion, unstable housing, insurance access, food insecurity, violence as a health issue, how health care institutions or systems are applying a racial equity lens to their policies and practices or otherwise addressing inequities or disparities, or other examinations of systemic problems that have become so apparent over the last few years.

Guidance is provided by AHCJ mentors through customized seminars on health care systems, conference calls and email consultations. The fellowship covers the cost of attending the seminars and the annual AHCJ conference, as well as a $2,500 project allowance to defray the cost of field reporting, health data analysis and other project-related research. In addition, you will receive a $5,000 fellowship award upon the successful completion of the project.

Journalism Health Disparities & Social Determinants of Health Health Care Access & Delivery +2 more

Pediatric Visiting Professorship

Rheumatology Research Foundation
Private
United States
Up to US $4,000
The Pediatric Visiting Professorship, funded by the Rheumatology Research Foundation, aims to recognize exceptional scientific abstracts from pediatric rheumatology fellows at ACR Convergence. This award facilitates knowledge sharing and promotes advancements in rheumatic disease care. The professorship spans two to three days and includes diverse teaching formats. Selected fellows receive a $1,000 honorarium for virtual visits or $1,500 for in-person engagements, along with reimbursement for travel expenses, enhancing the future of pediatric rheumatology education.
Musculoskeletal Diseases Arthritis Medical Education & Professional Training +1 more

AHCJ Sunshine Award

Association of Health Care Journalists (AHCJ)
Association/Society
United States
Unspecified amount

About

Building a community of journalists committed to better health care reporting.

We believe accurate, contextual and balanced health care reporting is more important than ever.

People depend on health care stories to make life-altering decisions every day.

Awards, Grants, & Fellowships

Ambitious freelancers who want to tackle an in-depth reporting project often find that the fee from a potential publisher doesn’t come close to covering their costs and time. Grants and fellowships can fill that gap, but freelancers have to know about them in order to apply. In this section, the Freelance Center is compiling a list of non-AHCJ grants, fellowships and awards (for when the hard work is done).

Sunshine Award

Presented by AHCJ’s Right-to-Know Committee

AHCJ’s Right-to-Know Committee established the Sunshine Award at Health Journalism 2026 as a way to elevate the work of journalists like STAT’s Bob Herman who fight for government transparency. We plan to continue this tradition annually from now on. Award winners receive free registration and a one-night hotel stay for our annual conference, a free year of AHCJ membership, a trophy and a certificate.

Journalism Epidemiology & Public Health Health Policy & Advocacy +2 more

Alzheimer’s Association: Center for Dementia Respite Innovation Grant (CDRI)

Alzheimer's Association
Private
United States
US $50,000 - US $100,000
The Alzheimer’s Association's Center for Dementia Respite Innovation Grant (CDRI) supports innovative respite care projects, aiming to improve person-centered dementia care across the U.S. With up to $20 million available over five years, the grant encourages local respite care providers to enhance their services through collaboration and innovative solutions. Recipients will receive training and assistance to ensure their programs are effective and sustainable, addressing the growing need for quality dementia care.
Dementia & Alzheimer’s Disease Caregiver Support / Respite Care

Single Ventricle Research Fund (SVRF) - Independent Investigator Track

Additional Ventures Foundation
Private
Countries
Up to US $600,000
The Single Ventricle Research Fund (SVRF) offers annual grants aimed at enhancing research and care for individuals with single ventricle heart defects. With awards of up to $600,000, the SVRF encourages innovative projects that align with the Additional Ventures Research Roadmap. This initiative not only supports novel treatments but also fosters collaboration across disciplines to address critical challenges in single ventricle heart disease management.
Cardiovascular Diseases & Systems Heart Disease Preventative Healthcare

Limited Competition: Renewal of Existing NINDS-Supported Clinical Trial Cooperative Agreement Awards (U01 - Clinical Trials Required)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Unspecified amount
This funding opportunity invites renewal applications for existing NINDS-supported clinical trial cooperative agreements (U01) that require additional time and resources. The National Institute of Neurological Disorders and Stroke (NINDS) expects applicants to request only what is necessary for trial completion, without introducing new aims. Discussions with NINDS prior to submission are encouraged. Eligible applications must be renewals of previously approved cooperative agreements under specified NIH funding announcements.
Neuroscience Neurological Diseases & Disorders Stroke

CCRP Initiative: NIH Countermeasures Against Chemical Threats (CounterACT) Basic Research on Chemical Threats that Affect the Nervous System (R01 Clinical Trial Not Allowed) (356935)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Up to US $300,000
The CCRP Initiative invites applications for basic research on chemical threats affecting the nervous system, including chemical warfare agents and toxic industrial chemicals. This funding aims to elucidate toxicity mechanisms, explore new toxic exposure manifestations, and identify targets for therapeutic development. Proposals should generate data relevant to understanding these toxic threats, with applications due by 5 PM local time. Optional Letters of Intent are encouraged 30 days prior to the proposal deadline.
Neuroscience Environmental Chemistry & Toxicology Neurological Diseases & Disorders

Troutville Volunteer Fire Department Scholarship Fund

Community Foundation Serving Western Virginia
Private
United States
Approximately US $1,000

Troutville Volunteer Fire Department Scholarship Fund

Fund provides higher educational scholarship assistance to deserving students.

Amount

  • $1,000+
  • non-renewable
Education - Higher Education Emergency Medical Care & Services Career / College Preparation +2 more

Neonatal Research Initiative- RFP

Little Giraffe Foundation
Private
United States
US $5,000 - US $10,000
The Little Giraffe Foundation is dedicated to supporting neonatal health through research grants ranging from $5,000 to $10,000. Since 2011, they have provided substantial resources to hospitals and institutions, focusing on both immediate and long-term health challenges faced by premature infants. Eligible applicants include scientists and healthcare professionals from U.S.-based institutions. The foundation aims to advance research in biological processes, genetics, clinical studies, and more, improving outcomes for vulnerable populations.
Obstetrics & Neonatal Care

National Trappers Foundation Grants

National Trappers Foundation
Association/Society
United States
Unspecified amount
The National Trappers Foundation (NTF) offers grants to individuals and organizations for projects related to furbearers. Founded in 1988, NTF supports educational and conservation initiatives that promote the management and restoration of furbearers and natural resources. Grants are available for research, habitat development, and educational programs. Contributions to NTF are tax-deductible, reflecting its commitment to conservation and community engagement.
Mammalogy

Little Giraffe Foundation: NICU Support Grants

Little Giraffe Foundation
Private
United States
Up to US $2,000
The Little Giraffe Foundation, a national non-profit based in Chicago, provides NICU Support Grants ranging from $100 to $1,000. Since 2011, they have positively impacted countless families by delivering over 32,000 gift bags and funding essential research. These grants aim to enhance the experience for parents and patients in neonatal intensive care units, supporting initiatives like holiday gift bags and resources for bonding with babies. Applications are welcomed from eligible U.S.-based institutions.
Obstetrics & Neonatal Care

Early Stage Investigator HIV/AIDS Research Using Nonhuman Primate (NHP) Models (R21 Clinical Trial Not Allowed) (348960)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Up to US $400,000
This funding opportunity aims to support Early Stage Investigators (ESIs) in conducting preclinical HIV/AIDS research using Nonhuman Primate (NHP) models. Eligible applicants must have at least two years of postdoctoral experience and be within ten years of their terminal degree. The initiative aligns with the NIH Strategic Plan for HIV and HIV-Related Research, targeting the reduction of HIV incidence, development of therapies, and advancement in research areas related to HIV.
HIV / AIDS

Incyte Healthcare Sponsorships

Incyte Corporation
Corporate
United States
Unspecified amount
Incyte Corporation, a biopharmaceutical leader, offers healthcare sponsorships to support organizations focused on improving patient care and access to healthcare information. Eligible applicants include medical schools, associations, non-profits, advocacy groups, and hospitals. Requests should align with Incyte's commitment to enhancing the lives of patients affected by cancer and other diseases, ensuring compliance with regulatory guidelines. Organizations must enter a written agreement with Incyte to receive funding.
Cancer / Oncology Diseases & Conditions Nursing +2 more

CFF Innovation Grants

COLIN FARRELL FOUNDATION
Private
United States
US $10,000 - US $50,000

About Colin Farrell FoundationThe Colin Farrell Foundation is committed to transforming the lives of individuals and families living with intellectual disability through education, awareness, advocacy, and innovative programs. Inspired by his two sons, he is excited and deeply humbled by the hope that the Colin Farrell Foundation can help those who the larger systems of governance have neglected.

CFF Innovation GrantsWe’re looking for bold, scalable solutions focused on one or more of these priority areas:

  • Affordable co-housing models for individuals and families
  • Employer-partnered day programs and inclusive job opportunities
  • Tools and technologies that enhance accessibility at home and in community spaces
  • Cross-sector collaborations between public, private, and nonprofit organizations

Intellectual / Developmental Disabilities Equitable & Affordable Housing Volunteerism & Philanthropy

Grief Reach: Changemaker Supported Community Expansion Cycle - up to $110,000

National Alliance for Children's Grief (NACG)
Private
United States
Up to US $110,000
The Grief Reach: Changemaker Supported Community Expansion Cycle offers up to $110,000 to enhance community programs for grieving children. Organizations are encouraged to innovate and expand their services to better meet community needs. The initiative, in partnership with the Judi’s House/JAG Institute, emphasizes training and resources for effective program evaluation over a three-year period, culminating in impactful community expansion projects.
Children’s Mental Health Mental Health & Psychiatric Diseases Family Services +1 more

Exploratory Clinical Trial Grants in Arthritis and Musculoskeletal and Skin Diseases

National Institutes of Health
Federal Government
American Samoa, Guam +4 more
US $300,000 - US $600,000
The National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) is launching a funding opportunity for Exploratory Clinical Trials Grants. This program aims to support innovative clinical trials that enhance the understanding and treatment of arthritis and other musculoskeletal and skin conditions. Research proposals should focus on early-stage trials, including first-in-human studies, dose-finding, and biomarker evaluation. The initiative encourages the translation of promising laboratory findings into effective clinical practices, ultimately improving patient outcomes.
Musculoskeletal Diseases Skin Diseases & Dermatology Arthritis

Allergic Respiratory Diseases Award

American Lung Association
Private
United States
Up to US $150,000
The Allergic Respiratory Diseases Award, supported by the American Lung Association and the American Academy of Allergy, Asthma & Immunology, aims to bolster research in allergic respiratory diseases. Designed for faculty in Clinical Allergy and Immunology at academic medical centers, this award offers $75,000 annually for up to two years. It seeks to empower researchers at pivotal points in their careers, enhancing understanding and treatment of these conditions while promoting lung health.
Respiratory Diseases & Systems Allergies & Allergic Diseases Immune System Diseases

NIAMS Clinical Trial Implementation Cooperative Agreement

National Institutes of Health
Federal Government
American Samoa, Guam +4 more
More than US $250,000
The National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) is inviting applications for the Clinical Trial Cooperative Agreement Program. This funding opportunity supports investigator-initiated, interventional clinical trials at various phases. Initial funding will facilitate the preparation needed to start trials, with successful milestones leading to further support. NIAMS emphasizes hypothesis-driven trials that promise significant clinical impact within its research mission.
Musculoskeletal Diseases Arthritis Skin Diseases & Dermatology

SAF National Awards Program: Gifford Pinchot Medal

Society of American Foresters (SAF)
Association/Society
United States
More than US $500
The Gifford Pinchot Medal, awarded by the Society of American Foresters, honors exceptional contributions by forestry professionals in North America. Recognizing achievements in administration and practice, this medal is presented every odd-numbered year at the SAF national convention. Recipients receive a $500 honorarium, complimentary registration, and up to $500 for travel expenses. This prestigious award highlights the importance of leadership and innovation in the forestry profession.
Forestry

Virginia Valk Fehsenfeld Scholarship

Grand Rapids Community Foundation
Private
United States
Unspecified amount

Generally the Community Foundation's scholarships are awarded to applicants who have high financial need. Applicants with household income exceeding $100,000 are less likely to be awarded, but applying will allow you to be considered for targeted scholarships.

Virginia Valk Fehsenfeld Scholarship

Open to full time undergraduate students who are Kent County residents studying education, dietetics, nutrition, or human services and have a minimum 3.4 GPA.

Education Teacher Development & Training Education - High School +2 more

SAF National Awards Program: Honorary Membership

Society of American Foresters (SAF)
Association/Society
United States
Unspecified amount
The SAF National Awards Program recognizes exceptional contributions to forestry through its Honorary Membership award. This accolade is presented to individuals whose impact on the field is acknowledged by their peers, highlighting their distinguished service in advancing forestry knowledge and societal awareness. Awardees receive lifetime membership in SAF along with complimentary convention registration. The program seeks to honor those, including non-professional foresters, who have made significant strides in forestry, both domestically and internationally.
Forestry

Scleroderma-Related Lung Disease— The Debra Lurvey Memorial Research Grant

National Scleroderma Foundation
Private
United States
US $200,000
The Scleroderma-Related Lung Disease— The Debra Lurvey Memorial Research Grant, provided by the National Scleroderma Foundation, aims to support research in scleroderma-related lung disease. With a funding amount of $200,000, the grant encourages established investigators to explore innovative solutions and enhance understanding of this condition, ultimately working towards improving the quality of life for affected individuals and advancing medical knowledge in the field.
Rare Diseases Immune System Diseases Interstitial Lung Disease

SAF National Awards Program: John A. Beale Memorial Award

Society of American Foresters (SAF)
Association/Society
United States
More than US $500
The SAF National Awards Program includes the John A. Beale Memorial Award, recognizing exceptional voluntary service in forestry by SAF members. Established to honor John Beale's legacy, this award is presented at the SAF national convention and includes a $500 honorarium, complimentary registration, and up to $500 for travel expenses. Nominees must demonstrate sustained commitment to the SAF and its mission, showcasing leadership and promotion of forestry principles.
Forestry

Survivorship and Supportive Care Research Grant

St Baldricks Foundation Inc
Private
United States
Up to US $50,000

St. Baldrick's Foundation

The St. Baldrick's Foundation is a volunteer and donor powered charity committed to supporting the most promising research to find cures for childhood cancers and give survivors long and healthy lives. It started with a friendly dare: would you shave your head to raise money for kids’ cancer research? What happened next would change the world. This bold act of baldness has gained major momentum, since its start in 2000. Today, we have more than 1,000 head-shaving events taking place around the world at pubs, restaurants, schools, churches, parks, firehouses, military bases – you name it. It is our constituents’ way of changing the world, in a meaningful way. Volunteers also raise funds through athletic challenges, livestream fundraisers and many other activities.

Since the Foundation's first grants as an independent charity in 2005, St. Baldrick's has invested more than $380 million in childhood cancer research grants worldwide.

About Allied World

Allied World Assurance Company Holdings, Ltd, through its subsidiaries, is a global provider of insurance and reinsurance solutions. The company operates under the brand Allied World and has supported clients, cedents and trading partners with thoughtful service and meaningful coverages since 2001. Since the inception of St. Baldrick’s, Allied World has supported childhood cancer research through the Foundation, and it is the largest of many reinsurance company sponsors, making this life-saving mission a top priority.

Survivorship and Supportive Care Research Grant

These grants are for specific one-year research projects which are hypothesis-driven and focus on areas related to survivorship and supportive care of children and adolescents with cancer. Examples include but are not limited to: studies related to the burden of morbidity, cause-specific mortality, understanding the pathogenesis of treatment-related complications, patient-reported outcomes or quality of life, health communication, health promotion, and psychosocial support across the trajectory from diagnosis to survivorship or end-of-life care.

Projects must have direct applicability and relevance to pediatric cancer. They may be in any discipline of basic, clinical, translational, or epidemiological research.

Cancer / Oncology Pediatric Cancers Patient Care & Services

SAF National Awards Program: Young Forester Leadership Award

Society of American Foresters (SAF)
Association/Society
United States
More than US $500
The Young Forester Leadership Award, presented by the Society of American Foresters (SAF), recognizes exceptional leadership from young forestry professionals under 40 years old. This award highlights contributions to forestry through innovative projects and sustained leadership roles. Recipients receive a $500 honorarium, complimentary registration for the SAF national convention, and support for travel expenses up to $500. This prestigious accolade aims to encourage the next generation of forestry leaders to excel in their professional endeavors.
Forestry

Community Care Corps RFP

Community Care Corps
Federal Government
United States
US $30,000 - US $200,000

Request for Proposals

Community Care Corps encourages organizations across the country to apply for 18-month grants ($30,000–$200,000) to develop and scale innovative volunteer programs that provide nonmedical assistance to older adults, adults age 18 and older with disabilities and family caregivers.

Projects funded through this initiative will increase the number of community-based volunteer programs available to provide nonmedical assistance while decreasing the number of older adults, adults with disabilities, and family caregivers who need assistance in maintaining independence in the community but are unable to obtain help. In doing so, the initiative will strengthen community-based supports that help people maintain independence, reduce unmet needs, and improve overall well-being.

Senior Services Caregiver Support / Respite Care Disability Care & Services +1 more

RSLAAIS Leadership Award

American Academy of Allergy, Asthma & Immunology (AAAAI)
Association/Society
United States
Unspecified amount
The RSLAAIS Leadership Award, presented by the American Academy of Allergy, Asthma & Immunology (AAAAI), honors exemplary leaders within state, regional, or local allergy societies. This prestigious award recognizes individuals for their significant contributions to community involvement, clinical education, and the advancement of the AAAAI's mission. Candidates are nominated by the RSLAAIS Board of Governors and must demonstrate a commitment to enhancing their local allergy societies and the broader medical community.
Asthma Vaccines & Immunizations Immune System Diseases

Operating Grants for Nonprofits in Pennsylvania Highlights

Looking for operating grants for nonprofits in Pennsylvania?


Read more about each grant below or start your 14-day free trial to see all operating grants for nonprofits in Pennsylvania recommended for your specific programs.

Last updated: October 5, 2026. Next update: November 1, 2026.

Grant Insights : Operating Grants for Nonprofits in Pennsylvania

Grant Availability

How common are grants in this category?

Common — grants in this category appear regularly across funding sources.

300+ Operating grants for nonprofits in Pennsylvania grants for nonprofits in the United States, from private foundations to corporations seeking to fund grants for nonprofits.

100+ Operating grants for nonprofits in Pennsylvania over $25K in average grant size

88 Operating grants for nonprofits in Pennsylvania over $50K in average grant size

45 Operating grants for nonprofits in Pennsylvania supporting general operating expenses

300+ Operating grants for nonprofits in Pennsylvania supporting programs / projects

600+ Grants on Instrumentl focused on Food Access & Hunger

1,000+ Grants on Instrumentl focused on Education - K through 12

Grant Deadline Distribution

Over the past year, when are grant deadlines typically due for Operating grants for Nonprofits in Pennsylvania?

Most grants are due in the second quarter.

Q1
27.0%
Q2
28.4%
Q3
23.4%
Q4
21.2%

Typical Funding Amounts

What's the typical grant amount funded for Operating Grants for Nonprofits in Pennsylvania?

Grants are most commonly $28,750.

$500 $500 Min.
$28,750 $28.8 K Median
$465,890 $465.9 K Average
$40,331,313 $40.3 M Max.

Average Grant Size

What's the typical amount funded for Pennsylvania?

Grants are most commonly $120,832.

$120,832

Total Number of Grants

What's the total number of grants in Operating Grants for Nonprofits in Pennsylvania year over year?

In 2024, funders in Pennsylvania awarded a total of 114,767 grants.

2022 101,760

2023 105,380

2024 114,767

Top Grant Focus Areas

Among all the Operating Grants for Nonprofits in Pennsylvania given out in Pennsylvania, the most popular focus areas that receive funding are Philanthropy, Voluntarism & Grantmaking Foundations, Education, and Human Services.

1. Philanthropy, Voluntarism & Grantmaking Foundations

2. Education

3. Human Services

Funding Over Time

How is funding for Operating Grants for Nonprofits in Pennsylvania changing over time?

Funding has increased by 39.90%.

2022 $9,486,595,381

2023 $9,869,112,363
4.03%

2024 $13,806,751,647
39.90%

Pennsylvania Counties That Receive the Most Funding

How does grant funding vary by county?

Montgomery County, Philadelphia County, and Allegheny County receive the most funding.

County Total Grant Funding in 2024
Montgomery County $11,058,341,664
Philadelphia County $2,487,099,923
Allegheny County $1,915,534,930
Chester County $846,675,579
Centre County $563,407,306