Best Small Grants for Nonprofits in Pennsylvania

The Marcy Shulman Memorial Organization Grant Program, established by the Colburn-Keenan Foundation, supports organizations improving the lives of individuals with chronic illnesses, particularly within the bleeding disorders community. Proposals should enhance health and quality of life, with examples including educational programs and facility upgrades. Only 501(c)3 organizations are eligible, and they may receive one grant per cycle. Applications must be submitted at least two months prior to the project start date.

The Retina Society, Inc.

The Retina Society was founded in 1968 exclusively for educational and scientific purposes concerning the diagnosis, care and treatment of diseases and injuries to the retina. The Retina Society began as an outgrowth of alumni meetings of Retina Associates, a retina practice founded in Boston in 1951 by Charles L. Schepens. Dr. Schepens is credited with establishing retina surgery as a sub-specialty.  

Our mission is to reduce worldwide visual disability and blindness by promoting the education and professional interaction of vitreoretinal specialists, providing optimal care for patients with vitreoretinal diseases, and encouraging, through clinical and basic research, the discovery and development of new means to further patient care.

Retina Society Underrepresented in Medicine (RESOURCE) Mentoring Program

The Retina Society Underrepresented in Medicine (RESOURCE) Mentoring Program was created to engage and interest ophthalmology residents from underrepresented populations* in research and in pursuing careers in the retina subspecialty through dedicated mentoring exposure. The program will pair ophthalmology residents from underrepresented backgrounds with Retina Society mentors, with the goal of providing the residents with research and career mentorship.

*The American Association of Medical Colleges definition of underrepresented in medicine is: "Underrepresented in medicine means those racial and ethnic populations that are underrepresented in the medical profession relative to their numbers in the general population." We define the following groups as underrepresented: Black (African American or African), Latino/Hispanic, American Indian, Alaska Native, Native Hawaiian or Pacific Islander. We will also be considering applicants from LGBTQIA+ and socioeconomically underprivileged backgrounds.

Mentors will work with their designated mentees on research projects that will be presented at the Retina Society Annual Meeting in 2027 and submitted for publication consideration. Mentors and mentees will be acknowledged at the Retina Society Annual Meeting.

The A. O. Smith Foundation, established in 1955, provides grants to support charitable, educational, and human services organizations primarily in communities where A. O. Smith Corporation operates. With a mission focused on enhancing community well-being, the Foundation promotes education, arts, culture, and health initiatives. It encourages employees to engage in volunteerism, fostering a culture of community involvement. Notably, the Foundation does not fund politically active organizations or those primarily aiming to influence legislation.

BrightFocus Foundation offers Alzheimer's Disease Research Grants to support innovative research aimed at understanding, preventing, and treating Alzheimer's disease. These grants encourage applications from diverse backgrounds, fostering creativity in scientific research. The program includes Standard Awards for early investigators with a maximum funding of $300,000 for three years and Postdoctoral Fellowship Awards for young researchers at $200,000 for two years, promoting the development of independent research careers.

About

What is FOXG1 Syndrome?

FOXG1 syndrome is a rare genetic neurodevelopmental disorder caused by a mutation in the FOXG1 gene. FOXG1 gene is one of the first and most important genes for early brain development and when impaired, causes developmental disabilities as well as medical complexities, including epilepsy.

Every child born with FOXG1 syndrome is unique as FOXG1 manifests as a spectrum where symptoms and severity vary between individuals. Our patient data shows characteristics of children with FOXG1 syndrome include: non-speaking, non-ambulatory, experience seizures, feeding problems, cortical vision impairment, movement disorders, and developmental delays. Less-severely-affected FOXG1 children often present with (ASD) Autism Spectrum Disorder as FOXG1 is an autism related gene. FOXG1 syndrome is found equally among both females and males and is geographically more prevalent where diagnostic testing is more advanced. 

Our Story & Mission

When our children were diagnosed with FOXG1 syndrome, we were told there was nothing we could do. No treatments, no concerted research underway, no roadmap. Just a devastating diagnosis for a disorder few had ever heard of.

But we refused to accept that. 

Research Assets & Grants

FOXG1 Scientific Research Project Grants

The FOXG1 Research Foundation is providing grants to scientists to deepen the understanding of the biology of FOXG1 with the goal of identifying innovative therapeutic strategies and finding a cure.

For the next few years, these are the strategic focus areas:

• Experiments designed to understand when, where, and levels of FOXG1 needed for normal brain development in mice
• Experiments designed to understand the biophysical properties of FOXG1 mutations
• Experiments designed to gain insights into the molecular and cell biological pathways regulated by FOXG1  

Retina Research Foundation

Across the nation, there were only a handful of voluntary groups with the will and the means to tackle retinal disdorders. Retina Research Foundation, established in 1969, was one of those organizations. By the 1980s, RRF had become a voice for retina research in an effort to reduce the incidence of retinal disease, which was fast becoming the leading cause of blindness in developing countries.

Undaunted, the Foundation steadily raised funds each year for vision scientists who were nationally recognized for their work in retina research. Government funding for eye research increased dramatically, and the field of retina research matured. As this body of knowledge grew, RRF programs were expanded to include major awards that recognize established retina scientists and contribute to their ongoing research. The Foundation also developed scientific exchange programs to disseminate knowledge of the dramatic advances that were being made in the laboratory.

RRF Pilot Study Grants

The mission of the Retina Research Foundation is to reduce retinal blindness worldwide by funding programs in research and education. As a public charity, RRF raises funds from the private sector and the investment of its endowment funds.

RRF is currently welcoming pilot study grant applications for the 2027 grant period. Each grant application must be signed by the principal investigator and either their Department Chair or Dean of Research.

The Land Trust Bird Conservation Initiative, led by the Cornell Lab of Ornithology, aims to support land trusts in conserving private lands for bird protection. With funding for up to fourteen grants, the initiative encourages capacity building and management projects that enhance bird habitats. Eligible organizations can apply for grants to expand conservation efforts through collaboration and innovative strategies, fostering partnerships that leverage additional funding and community support. This initiative highlights the importance of birds in land stewardship and conservation.

The Gupta Family Foundation Grant aims to empower disadvantaged individuals by providing financial support to organizations that foster self-reliance. Headquartered in Herndon, Virginia, the foundation offers grants ranging from $5,000 to over $250,000, prioritizing smaller organizations with a strong commitment to their missions. Eligibility typically includes US-based IRS 501(c)(3) entities, with operations extending to countries like India and Kenya. The foundation emphasizes mission alignment and effective resource allocation to ensure maximum impact.

The AAD Shade Structure Grant Program provides funding up to $8,000 for non-profit organizations and public schools to install shade structures, promoting sun safety for children and teenagers. Applicants must demonstrate a commitment to sun safety, including a year-long awareness program, and submit a letter of recommendation from an AAD dermatologist. The program aims to enhance outdoor safety, supported by donations from members and organizations.

The Emergency Department Alternatives to Opioids Program aims to implement practices that offer alternatives to opioid treatments in hospitals. This initiative focuses on reducing the harmful consequences of opioid use for pain management, promoting safer treatment options, and minimizing the risk of opioid misuse and overdose. Specifically, it targets healthcare organizations to enhance their pain care strategies, ultimately contributing to better patient safety and health outcomes.

American Psychiatric Association Foundation

There is no health without mental health. The APA Foundation is working in your community to provide the support and resources we all need to prioritize mental wellbeing where you live, learn, work, worship, and play.

Backed by the medical expertise of the APA and industry-leading strategic partners, we administer community-changing programs, public education campaigns, grants, and awards aimed at increasing mental health literacy, connecting individuals to needed care, and shifting attitudes toward mental health.

Our Mission is to promote the mental health and well-being of individuals and communities. Our Vision is a mentally healthy nation for all – where we live, learn, work, worship, and play.

Diversity Leadership Fellowship

The Diversity Leadership Fellowship identifies and motivates minority psychiatry residents or those interested in minority and vulnerable populations to become well equipped to teach, administer, and provide culturally competent, evidence based mental health and substance abuse services to diverse minority groups and at-risk populations. These populations include—but are not limited to—American Indians/Native Alaskans, Asian Americans/Native Hawaiians/Native Pacific Islanders, Blacks/African Americans, Hispanics/Latinos, LGBTQ, and religious minorities. Program Benefits:

• Sponsorship to attend a minimum of four APA meetings:
  • Two APA Annual Meetings
  • Two Fellowship Forums
• Develop leadership skills in the field of psychiatry and advance understanding of the life experiences of racial ethnic minority communities
• Gain an understanding of APA/APAF Governance through observation and service on an APA Council, Committee, or APAF initiative
• Have the opportunity to sit on the APAF Board of Directors as a non-voting member (one Diversity Leadership fellow allowed)
• Cultivate a professional network with psychiatrists interested in minority mental health and services through exclusive events and engagements with APA leaders. Establish relationships and peer-mentorship with a diverse group of resident fellows with similar career interests and goals

The Ittleson Foundation Environmental Program Grants support innovative projects that enhance environmental activism through education and grassroots efforts. In 2025, grants will focus on initiatives that strengthen environmental movements and engage new constituencies, particularly in environmental equity. The Foundation has provided resources since 1932 to improve public policy and community welfare, alternating its grantmaking focus annually between mental health and environmental initiatives.

The Majestic Realty Foundation, established in 2002, champions active philanthropy by addressing critical community needs across eight regions in the U.S. Focused on youth, education, health, family support, and violence prevention, the Foundation fosters sustainable community development. Through initiatives like the Los Angeles Youth Leadership Council, it empowers young leaders while encouraging employee volunteerism. By partnering with local nonprofits, the Foundation strengthens community ties, ensuring lasting impact against challenges such as homelessness and youth violence.

The Conservation Service Corps Grants, funded by Great Outdoors Colorado, support outdoor recreation and natural resource projects by hiring youth and veterans through conservation service corps. Annually, $1.5 million is allocated for these initiatives, enabling crews to tackle various projects like trail maintenance, invasive species mitigation, and wildlife habitat improvement. This program not only enhances natural resources but also provides job training and leadership skills to over 1,700 young participants each year.

The Ross Wagner Foundation Scholarship offers significant financial support for students pursuing degrees in various engineering fields, including civil, mechanical, and electrical engineering. With awards up to $25,000 annually, students can receive up to $100,000 over four years. Applicants must maintain a B average, work in engineering labs, and be enrolled in top-ranked engineering schools in the U.S. and Canada. This scholarship honors Ross Wagner's legacy, promoting excellence in engineering education.

The MBF Small Grants Program supports conservation projects for monarch butterflies and their habitats, primarily in Mexico. It aims to fund initiatives focusing on habitat conservation, scientific research, education, and sustainable development. Grants are primarily awarded to Mexican organizations and individuals, with a preference for those with relevant experience. Projects should enhance local livelihoods and promote environmental awareness within the Monarch Butterfly Biosphere Reserve.

About us

SIR Foundation is a scientific foundation dedicated to fostering research in interventional radiology for the purposes of advancing scientific knowledge, increasing the number of skilled investigators, and developing innovative therapies that lead to improved patient care and quality of life. The foundation is committed to fostering the development and enhancement of innovative, minimally invasive, image-guided therapies from inception to mature clinical application and to conduct educational programs in the service of its mission.

Excellence in Innovation Award

Fund compelling, novel ideas that lead to improved health outcomes in IR.

About

Interventional radiologists create and introduce novel, minimally invasive procedures and devices that help solve some of our toughest medical challenges. To continue this rich history of innovation in IR, the purpose of this award is to fund compelling, novel ideas that lead to improved health outcomes in IR.

Innovation, for this purpose, is broadly defined as any use of emerging methods, new devices, new procedures or new technologies, such as artificial intelligence and nanotechnology, that display an exceptional degree of potential for transforming and advancing the specialty of interventional radiology.

The Annual Meeting Research Award Committee selects one recipient for this award each year.

The recipient will receive:

• Complimentary annual meeting registration
• Travel stipend up to $1,000
• The opportunity to present their research as well as meet peers, network with senior scientists and participate in learning opportunities at the SIR Annual Scientific Meeting
• Recognition during the SIR Annual Scientific Meeting

The Global Down Syndrome Foundation's Education Awards support innovative educational programs aimed at enhancing the lives of individuals with Down syndrome. This initiative encourages applications for workshops, conferences, and webinars focused on research and medical advancements. Eligible applicants must be members of the foundation or recognized 501(c)(3) organizations, ensuring impactful contributions that benefit the Down syndrome community. With no funding limits for consecutive years, this program promotes significant educational outreach and advocacy.

About Pfizer Grants

Pfizer supports the global healthcare community’s independent initiatives (e.g., research, quality improvement or education) to improve patient outcomes in areas of unmet medical need that are aligned with Pfizer’s medical and/or scientific strategies.

Interventional Research Studies of Brentuximab Vedotin-Based Novel Combinations in AITL and PTCL-NOS

This competitive program is designed to support interventional InvestigatorSponsored Research aimed at generatin clinical evidence for brentuximab vedotin in novel combination approaches in angioimmunoblastic T-cell lymphoma (AITL) and peripheral T-cell lymphoma–not otherwise specified (PTCL-NOS).

Project Types and Area of Interest

Studies considered for Pfizer support should address key clinical and scientific gaps in the use of brentuximab vedotin in AITL and PTCL-NOS irrrespective of CD30 expression, with a focus on evaluating the safety and efficacy of novel brentuximab vedotin–based combinations with therapies available for PTCL treatment that are supported by a clear scientific rationale grounded in mechanism of action and/or disease biology.

Better Food Policy Fund 

Since its inception, the Better Food Policy Fund has set its strategic direction in a participatory fashion. We are intentionally building capacity for engagement to ensure the Fund aligns with the needs of food policy council stakeholders.   

Thus far, the Fund has engaged 300+ food policy council stakeholders to help co-develop the Fund. We are immensely grateful for the individuals who helped shape the initial direction of this fund. We view this growing stakeholder audience as the people to whom the Fund’s governing body, the Independent Advisory Committee, is ultimately accountable.

Grantmaking

The Better Food Policy Fund invests in US-based food policy councils, empowering community and government collaboration for progressive food policy. We utilize participatory processes to enhance equity and redistribute power in the funding landscape. We seek to celebrate and uplift the work of food policy councils, and believe every food policy council is worthy of financial support.

We define “food policy councils” as councils, networks, coalitions, or other groups working across boundaries at the tribal, municipal, county, state, or regional level.  

We support actions aimed at ensuring an enabling environment for policy change, such as: 

• increasing levels of inclusive and equitable stakeholder engagement in public processes
• engaging systems thinking when tackling complex food system challenges
• facilitating collaboration with and across local government agencies and departments 
• developing or revising local policies and plans  

We define “better food policy” as practices, procedures, ordinances, laws, etc. of governing institutions which strengthen community-based food systems.

We define “civic collaboration” as people joining together at the intersection of community and government to address public issues.

The Young Investigator Grant from Alex's Lemonade Stand Foundation supports early career researchers in pediatric oncology. This grant, offering up to $50,000 per year for three years, aims to cultivate promising researchers and encourage innovative research ideas. With a commitment to changing the lives of children with cancer, ALSF plays a crucial role in funding impactful research and empowering the next generation of scientists dedicated to this vital cause.

The Early Career Research Programs: 'A' Award Grant by Alex's Lemonade Stand Foundation aims to support promising early career scientists in pediatric oncology. This grant fosters innovation in childhood cancer research by funding original projects that are not currently financed. Applicants must demonstrate a commitment to pediatric cancer investigation and provide a solid career development plan with mentorship. The funding can reach up to $800,000 over four years, with a maximum of $200,000 available annually.

The Society of Toxicology offers the Supplemental Training for Education Program (STEP), which provides up to $1,000 to support graduate students in toxicology seeking additional training to address skill gaps. Eligible applicants must be PhD students who have completed coursework and passed comprehensive exams. The funding covers workshops or courses not available through their graduate program, enhancing career prospects in toxicology.

The A Woman’s Work Founders Scholarship, provided by the Longmont Community Foundation, supports women in the Longmont and St. Vrain Valley area who demonstrate financial need and a commitment to their education. With awards ranging from $500 to $5,000, this scholarship prioritizes applicants who have shown resilience in overcoming challenges. By empowering women, the scholarship aims to foster individual achievement and strengthen the community, creating pathways to sustainable futures.

The Braly Trade / Vocational Scholarship, offered by the Longmont Community Foundation, supports individuals over 21 pursuing a trade or vocational education. This one-time award of $5,000 is allocated for tuition, fees, books, and other educational expenses. The scholarship honors the Braly family’s legacy in trades and aims to empower recipients to positively impact their communities. Applicants must be high school graduates or hold a GED and plan to attend an accredited institution in the U.S.

The Drs. James and Wanda Trefil Science Scholarship, offered by the Kosciuszko Foundation, supports undergraduate students majoring in natural sciences such as physics, biology, and chemistry. This competitive scholarship awards $5,000 and is available to U.S. citizens of Polish descent who maintain a GPA of 3.5 or higher. Applicants must be full-time students and can only receive the scholarship once, with a deadline for letters of recommendation set for March 3, 2026.

Community Foundation for Mason County, MI

The mission of the Community Foundation is to engage donors and connect them with opportunities to make a lasting impact, build community endowment, provide leadership on key issues, and make grants that reflect the communities we serve.

Scholarships

If you’re a high school or homeschooled senior, current college student, early college senior, or a student pursuing a master’s or doctoral degree, the Community Foundation for Mason County may have a scholarship for you.

Marlene Schoenberger Scholarship

This scholarship has been made possible by the generosity of Tamar Schoenberg, who established the Marlene Schoenberger Scholarship Fund of the Community Foundation for Mason County in memory of her mother, Marlene. This scholarship is presented to Mason County students pursuing Fine Arts and Performing Arts.