Best Operating Grants for Nonprofits in Puerto Rico

The FY26 Traumatic Brain Injury and Psychological Health Research Program (TBIPHRP) aims to support impactful health services research that connects research, practice, and policy. It emphasizes building real-world evidence for interventions and clinical guidelines tailored to specific populations. Key features include requirements for clinical trials, preliminary data, and community-based participatory research approaches. The program also offers an Early-Career Investigator Partnering Option to foster collaboration between seasoned and emerging researchers.

The National Institutes of Health (NIH) invites applications for clinical trials and ancillary studies within its funded research networks. This program supports multi-center trials, emphasizing collaborations and responsive projects. The UG3/UH3 cooperative agreement will fund an initial 2-year planning phase, with a potential 5-year implementation phase. This notice is to prepare applicants for future submissions, as applications are currently not being solicited. Prioritization will be given to studies aligned with network capabilities.

The NCI Research Specialist Award (R50) supports clinician scientists involved in NCI-funded clinical trials. This funding opportunity encourages the development of stable research careers by providing salary support and autonomy, allowing clinician scientists to contribute to national clinical trial development and implementation. They play a critical role in sustaining the NCI clinical trials network without serving as principal investigators. This award aims to ensure continuity in cancer research careers.

The Center on Knowledge Translation for Disability and Rehabilitation Research (KTDRR Center) aims to enhance the use of relevant disability and rehabilitation research through effective knowledge translation. Serving as a key resource for NIDILRR grantees and the general public, the KTDRR Center's initiatives will support high-quality research dissemination. The project spans 60 months, including five 12-month budget periods, ensuring ongoing support for researchers and stakeholders in the field.

The Research With Activities Related to Diversity (ReWARD) program by the NIH aims to enhance research diversity and inclusion across the United States. It supports scientists contributing to Diversity, Equity, Inclusion, and Accessibility (DEIA) who lack current NIH funding. The program funds both scientific research and DEIA activities, addressing the needs of various NIH Institutes and Centers to foster a more diverse biomedical research landscape.

The National Center for Complementary and Integrative Health (NCCIH) seeks to fund interdisciplinary research on non-addictive natural products for chronic pain management. This initiative supports the NIH HEAL Initiative by emphasizing safe, prevention-oriented strategies. Research should focus on the holistic effects of natural products across various biological systems, optimizing dosages, and identifying optimal intervention timing to enhance therapeutic outcomes. The goal is to generate foundational insights that will guide future translational research for effective pain management.

The Rauschenberg Medical Emergency Grants, administered by the New York Foundation for the Arts, provide one-time funding up to $5,000 for artists facing unexpected medical emergencies. This program aims to alleviate financial burdens caused by medical costs, ensuring that artists can receive necessary care without delay. Eligible applicants must be practicing artists in visual arts, film, or choreography, and demonstrate financial need. This initiative supports artists of color, LGBTQ+ individuals, and those outside major coastal cities.

The Environmental Health Sciences Core Centers Program (P30) invites grant applications to support innovative research in environmental health. These centers serve as critical hubs for advancing the goals of the 2025-2029 NIEHS Strategic Plan, providing essential infrastructure and resources for collaborative research. By fostering community engagement and translational research, the program aims to enhance understanding of the connections between environmental factors, human biology, and disease, ultimately improving public health outcomes.

The Rehabilitation Research and Training Center (RRTC) focuses on enhancing the lives of parents with disabilities through research, training, and technical assistance. This initiative aims to develop evidence-based services and supports that empower parents in their caregiving roles. Funded by the US HHS: Administration for Community Living (ACL), the project spans 60 months with a commitment to fostering inclusive environments for families. The RRTC will explore innovative interventions and technologies to better support these parents in their daily challenges.

The Republic Services Community Grant Program supports local nonprofit organizations focused on neighborhood revitalization, safety, disaster relief, and social services. Eligible 501(c)(3) organizations can apply once annually through an online application process. The program emphasizes a non-discrimination policy, ensuring services are provided without bias. However, funding is not available for individuals, government entities, schools, or religious organizations. This initiative reflects Republic Services' commitment to community engagement and support.

The NIDCR Predoctoral to Postdoctoral Transition Award aims to enhance the diversity of the dental, oral, and craniofacial research workforce. This program supports exceptional graduate students from underrepresented backgrounds as they transition from PhD or dual degree programs (F99) to mentored postdoctoral positions (K00). Key deadlines for applications span from August 2024 to April 2027, ensuring ample opportunities for eligible candidates to apply.

The Mobile Learning Fund provides grants to adult literacy programs in the U.S. and Canada, enabling access to digital learning solutions. These grants support various online learning tools, such as New Readers Press, Learning Upgrade, and EnGen, aimed at enhancing literacy, math, and digital skills. Eligible programs must implement the solutions within 30 days and ensure active learner engagement. This initiative empowers educators to expand their reach and improve student outcomes through innovative digital resources.

The National Institute on Aging is announcing a Notice of Funding Opportunity for the Claude D. Pepper Older Americans Independence Centers (OAICs) award. This initiative aims to establish centers of excellence in geriatrics research and education to enhance the independence of older adults. Applicants are encouraged to identify a research focus that fosters collaboration and education in aging. Though applications are not currently being accepted, this notice allows potential applicants to prepare meaningful projects. The P30 activity code will be utilized.

The BJA FY 2026 John R. Justice Formula Grant Program offers loan repayment assistance to local and state prosecutors and public defenders who commit to three years of service. Administered by state agencies, this program aims to alleviate the financial burden on legal professionals dedicated to public service. Applications are due by November 10, 2026, providing a crucial opportunity for eligible beneficiaries to secure support for their educational loans.

The NIH Specialized Center Grant (Parent P50) aims to support multidisciplinary research programs with a specific scientific theme. Applicants must include an administrative core, research projects, and at least one resource core, demonstrating collaborative impact and synergy. This funding opportunity encourages innovative approaches to address major scientific objectives, fostering long-term research initiatives aligned with the NIH's mission. Applications should emphasize how their projects interconnect to achieve goals beyond individual efforts.

About Us

advancing the science of water ®

Who We Are

The Water Research Foundation (WRF) is the leading research organization advancing the science of all water to meet the evolving needs of its subscribers and the water sector. WRF is a 501(c)(3) nonprofit, educational organization that funds, manages, and publishes research on the technology, operation, and management of drinking water, wastewater, reuse, and stormwater systems—all in pursuit of ensuring water quality and improving water services to the public.

5418 - Optimizing PFAS Treatment Systems for Multi-contaminant Removal and Operational Benefits

Project Objectives

The DoW Spinal Cord Injury Translational Research Award supports innovative research to transform promising spinal cord injury findings into clinical applications. It features an Early-Career Partnership Option, requiring at least one early-career principal investigator. Collaborations with SCI community partners are essential for providing guidance throughout the project. This funding opportunity aims to enhance the effectiveness of spinal cord injury interventions and improve patient outcomes.

The FY26 Spinal Cord Injury Research Program Clinical Translation Research Award funds innovative clinical research aimed at bridging the gap to larger clinical trials. It focuses on accelerating the application of new techniques and improving patient outcomes through effective diagnosis and rehabilitation strategies. Key features include an Early-Career Partnership Option for principal investigators and a requirement for community partner involvement, ensuring collaborative research that meets real-world needs.

The NICHD Resource Program Grants in Bioinformatics aim to support the operation and enhancement of vital bioinformatics databases for research on animal models of embryonic development. These grants promote user training, data curation, and interoperability with NIH resources, ensuring wide dissemination of critical tools and resources to the research community. Applications are due by 5:00 PM local time, with optional Letters of Intent encouraged 30 days prior to the proposal deadline.

The FY26 Spinal Cord Injury Research Program Clinical Trial Award supports innovative clinical trials aimed at significantly improving spinal cord injury treatment. This funding opportunity encourages collaboration by allowing two Principal Investigators, including an early-career investigator, to drive the research forward. Applicants must partner with at least two SCI community members, ensuring that the project is informed by lived experiences and community needs throughout its development and implementation.

The Limited Competition: NIGMS Mature Synchrotron Resources for Structural Biology program aims to support advanced technologies at synchrotron facilities, providing biomedical researchers with cutting-edge X-ray beamlines, user training, and expert assistance. This initiative intends to continue funding through a reissued Notice of Funding Opportunity, inviting eligible organizations to apply. Applications will undergo NIH standard peer-review processes to ensure only the most meritorious proposals are funded.

The Francis Grants, established by Catholic Extension, offer funding for significant events in poor mission dioceses, such as the ordination of new Bishops, anniversaries, or papal visits. These grants also support educational endeavors for Bishops. Named in honor of Francis Clement Kelly, Francis Cardinal George OMI, and Pope Francis, the program aims to strengthen the Catholic faith across the U.S. Since 1905, Catholic Extension has invested over $500 million to assist communities in need.

The Land and Water Conservation Fund's Outdoor Recreation Legacy Partnership Program aims to enhance recreational opportunities in underserved communities through significant funding. Offering matching grants up to 50%, with awards ranging from $300,000 to $15,000,000, this program encourages applicants to connect with the Connecticut Department of Energy and Environmental Protection early in the application process for guidance. This initiative supports large-scale projects that improve access to recreational facilities.

The NCI Research Specialist Award (R50) supports non-tenure track scientists in cancer research who provide essential contributions within laboratories and core facilities. This award aims to enhance research careers for skilled scientists who do not seek independent investigator funding. Eligible candidates must possess an advanced degree, have at least two years of contribution to NCI-funded research, and dedicate a significant portion of their time to this work. The R50 offers salary support and travel funds to recognize and stabilize these vital roles in cancer research.

The NIH Mentored Patient-Oriented Research Career Development Award (K23) is designed to support the career development of individuals with clinical doctoral degrees committed to patient-oriented research. Key deadlines for standard applications include June 12, October 12, and February 12 from 2024 to 2027. Renewal and AIDS-related grant applications also have specific deadlines. This initiative aims to enhance research focused on improving patient care.

The Mission Boost Grants (MBG) by the American Cancer Society aim to enhance cancer research by funding projects that translate into human testing. These grants support investigators at all levels, offering resources for innovative clinical projects. The program consists of two funding stages: Stage I focuses on developing clear milestones for new treatments, while Stage II supports patient testing, ultimately contributing to advancements in cancer care and treatment.