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Search Through Puerto Rico Grants for Nonprofits in the U.S.

Find the perfect Puerto Rico grants for nonprofits on Instrumentl. 800+ Puerto Rico grants for nonprofits in the United States

800+ grants

$621.2M total

$250K median

800+
Available grants

$621.2M
Total funding amount

$250K
Median grant amount

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Last updated: April 6, 2026. Next update: May 3, 2026.

Rolling deadline

Unspecified amount

The Amgen Foundation, established in 1990, focuses on enhancing science education and strengthening communities. It supports nonprofit organizations that align with its mission, emphasizing teacher development and hands-on science experiences. Grants are awarded annually, with a commitment of $180 million to impactful programs. Eligible organizations include public schools and libraries, while ineligible requests involve individual support, religious organizations, and political activities. This approach aims to inspire the next generation of innovators through quality educational opportunities.

Rolling deadline

US $5,000 - US $15,000

The Auto Club Group Foundation focuses on creating a positive impact through grants that enhance traffic safety, driver education, and financial literacy across 14 U.S. states and two territories. With a mission rooted in community service, the foundation supports nonprofit organizations and government entities that align with its goals. Grants typically range from $5,000 to $15,000, addressing crucial areas such as traffic safety initiatives, financial literacy for K-12 students, and equitable access to driver education programs.

Rolling deadline

Unspecified amount

The Disaster Recovery Fund Grant aims to assist cooperatives and their members in recovering from natural disasters and emergencies. With nearly $750,000 allocated over the past four years, the fund supports essential aid such as food, clothing, housing repairs, and medical assistance. It covers uninsured expenses for cooperatives to regain viability. All applications are reviewed by the Executive Director and, for amounts over $1,000, by the CDF Board, ensuring a thorough evaluation process.

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Rolling deadline

Unspecified amount

The Amgen Foundation Inc focuses on non-healthcare donations and sponsorships that target humanitarian, social, educational, and community programs. They offer support to organizations outside the U.S. healthcare community, particularly those recognized as tax-exempt public charities. Eligible organizations must serve specific Amgen communities throughout the U.S. This initiative aims to enhance health outcomes and address critical societal needs, thereby reducing the burden of disease and improving lives.

Rolling deadline

Unspecified amount

The Republic Services Community Grant Program supports local nonprofit organizations focused on neighborhood revitalization, safety, disaster relief, and social services. Eligible 501(c)(3) organizations can apply once annually through an online application process. The program emphasizes a non-discrimination policy, ensuring services are provided without bias. However, funding is not available for individuals, government entities, schools, or religious organizations. This initiative reflects Republic Services' commitment to community engagement and support.

Rolling deadline

Up to US $250,000

The Social Impact Fund - Nationwide Grant supports innovative solutions addressing health care access, food security, and economic empowerment. Funded by the American Heart Association, this grant prioritizes community-led projects from organizations with under $10M in revenue. Eligible entities include both for-profit and nonprofit organizations based in the U.S. and Puerto Rico. Grants can provide up to $250,000 to initiatives that demonstrate measurable impact, fostering sustainable change in health and wellness.

Full proposal due Apr 24, 2026

US $20,001 - US $75,000

The National Film Preservation Foundation (NFPF) offers Matching Grants to support the preservation of significant American films. Nonprofit and public institutions can apply for projects involving complex preservation efforts, with cash stipends ranging from $20,001 to $75,000. Grants require a matching contribution of one-fifth of the project costs. Since its inception, the NFPF has aided numerous organizations in preserving culturally important films, ensuring their accessibility for future generations.

Full proposal due May 2, 2026

US $2,500 - US $20,000

The Syringe Service Program Grant, offered by The Comer Family Foundation, aims to enhance harm reduction initiatives by funding syringe access programs across the U.S. These programs provide sterile syringes, education, and support services to mitigate the risks associated with drug use, including HIV and hepatitis transmission. Priority is given to organizations in underserved areas and those led by marginalized communities. Grants are available for operational costs, program development, and staff training, with a focus on sustainability and local partnerships.

Pre proposal due May 8, 2026

US $5,000 - US $50,000

The Avant-Garde Masters Grants, provided by the National Film Preservation Foundation, support the preservation of significant American avant-garde films. Targeting public and nonprofit archives, these grants facilitate laboratory work to maintain artistic expressions that often defy mainstream distribution. Eligible projects should demonstrate the historical significance of the films, which must not have been preserved commercially. Funding ranges from $5,000 to $50,000, promoting the accessibility of American experimental film heritage.

Applications due May 18, 2026

US $20,000

The Region 2 Emergency Preparedness and Response Award aims to enhance community resilience against natural disasters and emergencies. It encourages projects focused on preparedness, mitigation, and recovery, addressing issues from weather disasters to local violence. Eligible applicants include organizations from Alabama, Florida, and other states in Region 2, prioritizing initiatives that support underserved communities and promote effective use of National Library of Medicine resources for health information access.

Applications due May 19, 2026

US $10,000 - US $40,000

The Abbey Mural Prize, established in 1932, supports the creation and restoration of public murals across the United States. This prestigious award, administered by the National Academy of Design since 1940, emphasizes projects that enhance community engagement and social activism through art. Grants typically range from $10,000 to $40,000, with a total annual funding cap of $125,000. Eligible applicants include artists, architects, and nonprofit organizations committed to impactful mural projects.

Applications due Jun 30, 2026

Up to US $30,000

The ACT on Health Equity Community Solutions Challenge Grant, backed by the Astrazeneca Foundation, aims to enhance health equity by funding community-based nonprofit programs. Since its inception in 2021, it has allocated over $2.6 million to initiatives addressing nutrition, healthcare access, and lung health for historically marginalized populations. Eligible US-based 501(c) organizations can apply, with a focus on projects serving underserved communities and improving health outcomes through targeted support.

Applications due Jul 3, 2026

US $100,000 - US $500,000

The Home Depot Foundation's Veteran Housing Grants Program aims to enhance the lives of U.S. veterans by funding the construction or rehabilitation of supportive housing. Grants, ranging from $100,000 to $500,000, are awarded to 501(c)(3) nonprofit organizations with experience in veteran housing. Since 2011, the Foundation has committed over $550 million to veteran causes and seeks to invest an additional $750 million by 2030, focusing on projects in major cities across the U.S.

Pre proposal due Aug 21, 2026

US $10,000 - US $40,000

The AIDS United Harm Reduction Futures Fund aims to combat the HIV epidemic by supporting organizations that provide syringe services and harm reduction programs. This initiative focuses on reducing health disparities for people who use drugs, promoting community-driven solutions, and ensuring equitable access to health services. Grants ranging from $10,000 to $40,000 will support organizations led by and serving Black, Indigenous, and other People of Color, especially in underserved areas. Direct service applications are currently prioritized.

Applications due Aug 31, 2026

Unspecified amount

The Mano Amiga Program, initiated by the Plaza Las Américas Foundation and the Plaza Del Caribe Foundation, aims to enhance social conditions in Puerto Rico. This program supports non-profits in key areas such as education, arts, health, and women's empowerment. The upcoming edition in August 2025 will focus on non-profits providing educational support, artistic training, health interventions for chronic diseases, and programs aimed at empowering women survivors of violence, fostering community resilience and growth.

Full proposal due Sep 1, 2026

Unspecified amount

The Bayer Fund Health & Wellness Grant Program aims to support organizations that provide education and resources for patients and caregivers facing cancer and cardiovascular diseases. Grants focus on assisting communities, particularly the African American population, in managing these health issues. Funding covers educational services, disease awareness, and access to care, with all activities to commence post-funding decisions. Eligible organizations must hold a 501(c)(3) status and operate within 55 miles of Bayer sites.

Applications due Sep 30, 2026

Up to US $50,000

The Encompass Health Therapy Grant offers up to $50,000 for research on the effectiveness of therapies in inpatient rehabilitation facilities. This funding aims to enhance understanding of neurological impairments and improve patient outcomes through evidence-based practices. Eligible projects must be conducted in the U.S. or Puerto Rico, require a defined research protocol, and adhere to ethical standards. The grant prioritizes studies on therapy impact, implementation science, and caregiver education, contributing to the advancement of rehabilitation care.

Applications due Oct 1, 2026

Up to US $1,080,000

The Hanna H. Gray Fellows Program, supported by the Howard Hughes Medical Institute, aims to enhance diversity in the academic research community. It provides funding of $250,000 and a $20,000 annual expense allowance for early-career researchers committed to fostering an inclusive scientific culture. Eligible applicants must hold a PhD or MD, commit to at least 75% research effort, and have no more than 24 months of postdoctoral experience. This initiative empowers fellows to become leaders in science.

Applications due Feb 24, 2027

US $10,000 - US $50,000

The Recordings at Risk Grant, administered by CLIR, supports the preservation of rare audio and audiovisual media of scholarly value through digital reformatting. With funding from The Andrew W. Mellon Foundation, the program aims to award $6.75 million across twelve competitions, offering grants between $10,000 and $50,000. It encourages U.S. nonprofit institutions to preserve vulnerable media, helping them to develop strategies for effective digital reformatting and promoting best preservation practices.

Applications due Feb 28, 2027

US $750

The AAFP Foundation offers Family Medicine Chapter Engagement Grants to support the philanthropic initiatives of its constituent chapters. Each chapter or chapter foundation can receive $750 to highlight programs focused on Student/Resident education, Member Outreach, or Public Health. This initiative not only showcases the impactful work being done at the chapter level but also aids in fundraising efforts, fostering stronger community connections and improving health outcomes.

Applications due Mar 1, 2027

Unspecified amount

The AAFP Family Medicine Chapter Alliance Grant Awards support the philanthropic efforts of AAFP Constituent Chapters and Chapter Foundations. Since 2006, these grants have been designed to fund activities that align with specific priority areas including education, outreach, and public health initiatives. Eligible applicants include AAFP Chapters and Foundations, focusing on projects that promote community health and wellness.

Applications due Mar 4, 2027

Up to US $25,000

The AARP Community Challenge Grant supports projects that enhance community living for residents aged 50 and older. With a focus on immediate improvements and long-term progress, grants range from $10,000 to $25,000, covering areas like public spaces, transportation, and digital literacy. Since 2017, AARP has awarded over $20.1 million through more than 1,700 grants across the U.S. Eligible organizations include nonprofits and government entities committed to serving the needs of older adults.

Applications due Mar 12, 2027

US $75,000 - US $115,000

The Climate Smart Communities Initiative (CSCI) Grant supports US-based projects aimed at enhancing community resilience against climate change. With a budget of $1.5-2 million, grants typically range from $75,000 to $115,000. CSCI prioritizes projects that focus on historically disinvested populations facing climate vulnerabilities, emphasizing equity, nature-based solutions, and community capacity building. The initiative encourages collaboration between climate adaptation practitioners and local government entities to address climate impacts effectively.

Applications due Mar 23, 2027

US $10,000

The NALAC Fund for the Arts offers organization grants focused on supporting Latinx artists and arts organizations in the U.S. and Puerto Rico. This funding initiative has invested over $6 million in the arts community, nurturing creativity and social change. Eligible applicants include organizations with a mission centered on Latinx arts. The program aims to enhance artistic excellence and community engagement, making it a vital resource for cultural production and social justice efforts.

Applications due Mar 23, 2027

US $1,500 - US $8,000

The Performing Arts Global Exchange Grant (PAGE) fosters international performing arts in the U.S., promoting cultural understanding through diverse programming. It offers support to nonprofit presenters who engage artists from a curated roster, focusing on underrepresented regions like Morocco and South Africa. Grants require public performances and community interaction, emphasizing outreach to underserved areas. PAGE is supported by Mid Atlantic Arts and the National Endowment for the Arts, aiming to enhance accessibility to global artistic expressions.

Applications due Apr 1, 2027

US $500 - US $5,000

The Bicycle Advocacy Grants Program, supported by New Belgium Brewing Co, aims to foster community engagement through bicycle projects. With over $11.3 million donated since its inception in 1995, the program focuses on breaking down barriers to cycling and promoting accessibility for all. Projects targeting increased ridership and addressing systemic inequities are prioritized. This initiative reflects New Belgium's commitment to sustainability and social equity, enhancing community connections through the joy of cycling.

Applications due Apr 2, 2027

Up to US $350,000

The Sex Worker Giving Circle Grant, launched by the Third Wave Fund, prioritizes funding for grassroots movements led by individuals directly impacted by gender oppression, especially within the sex work community. With a commitment to gender justice, the grant supports organizations that operate with a participatory approach to grantmaking, enabling them to address systemic inequalities. In recent years, the fund has distributed significant resources to empower and sustain these vital movements across the United States.

Showing 27 of 800+ results.

Puerto Rico Grants for Nonprofits Highlights

Puerto Rico grants for nonprofits provide funding to support education, disaster recovery, public health, and cultural preservation. The following grants empower organizations to address critical challenges, promote resilience, and foster sustainable development across Puerto Rico.

Search Instrumentl's Puerto Rico Grants Database

Find 800+ funding opportunities for nonprofits in Puerto Rico, with $621.2M available. Instrumentl helps organizations discover funding sources through automated deadline tracking, curated grant searches, and research-driven funder insights to drive local progress.

Last updated: April 6, 2026. Next update: May 3, 2026.