Best Operating Grants for Nonprofits in Puerto Rico

Our Mission

We strengthen our community for current and future generations by helping people make a difference in the lives of all.

We believe in our community’s lasting goodness. In fact, making sure our community is always a special place for us to live is why we’re here.

Scholarships

Through the generosity of our donors, we have more than $2 million in scholarships available in 2025 to students from more than 60 high schools. We offer scholarships to high school seniors, college and nontraditional students, and K-12 art and music camps and lessons.

The Academy Martial Arts Leadership Scholarship

Background

The Academy Martial Arts Leadership has been serving families in the Fox Cities since 1995. As the founders/owners, Jeff & Amanda Denu have been passionate about making our community stronger one Black Belt at a time teaching martial arts, while reinforcing respect, self-discipline, integrity, and excellence. Their passion with community involvement and creating a positive learning environment inspires others to be their personal best, and to make a difference every day.

The Day-End Dough-Nation® Program by Panera Bread exemplifies community generosity through the donation of unsold bakery products to local charities. This impactful initiative supports various organizations that distribute food to those in need, including shelters, health centers, and youth programs. By partnering with thousands of non-profits nationwide, Panera Bread not only reduces food waste but also plays a crucial role in addressing hunger and promoting equality within communities.

Bristol Myers Squibb Foundation Inc supports independent medical education to enhance healthcare professional competence and improve patient health outcomes. Their mission is to be a global leader in innovative medical education, focusing on evidence-based activities that address critical gaps in knowledge. By fostering excellence in healthcare, they aim to ensure measurable improvements in performance and patient outcomes across various disease areas.

The Gerber Foundation's Novice Researcher Grant aims to enhance the quality of life for infants and young children by funding innovative research in health and nutrition. With a focus on practical solutions that can be rapidly implemented, the grant supports projects addressing everyday challenges faced by young children and their caregivers. Eligible applicants include early-career researchers, with grants capped at $30,000, making it accessible for those looking to contribute to significant advancements in pediatric care.

The Mutual Self-Help Housing Technical Assistance Grants in Puerto Rico provide essential support to organizations aiding low-income families in constructing their own homes. These grants enable recipients to offer technical guidance and supervision, facilitating community-driven housing projects. Eligible entities include government non-profits and federally recognized tribes, while funding cannot be used for direct construction labor or purchasing materials. This program fosters self-sufficiency and strengthens community ties in rural areas.

Mission

The Foundation was established in December 2013 by Kathryn B. McQuade, after retiring from 33 years of working in the business community. I was blessed to have been born into a loving middle class family. My father worked very hard to insure that all of his children were given an opportunity for a good education and my mother, “a stay at home Mom’ was always there for us. My world was safe and comfortable. My life is in stark contrast to how much of the rest of the world lives. I continue to read of the terrible injustices waged against women and children globally and hope that this foundation can provide them the opportunity and resources to succeed. We will support organizations that help us achieve our goal of Striving to make sustainable improvements in women and children’s rights education and welfare.

Kathryn McQuade Foundation Grant

The Foundation will make timely decisions on your grant request and provide clear communications on our expectations of reporting progress.

Women

The Foundation’s goal is to provide women assistance and provide them an opportunity to succeed. Assistance can take many forms, however our goal is to help them become self sufficient and enable them to lift themselves out of poverty and provide for their children. Access to education, job training and professional skills, even access to capital in order to build a business are possible ways we will consider helping women to succeed. Grant requests should focus on enabling the women to sustain financial independence.

We look forward to hearing of the many creative ways organizations are working on helping women succeed through out the world. To help women is to help their children and the communities they live in.

Children

Too many children in the US and across the world live in poverty and lack the access to education. Education and/or appropriate skills training are necessary to break the cycle of poverty and crime. While the assistance to women may take many forms, the foundation’s focus for children will target education and/ or skills training. The Foundation is open to many ideas on how to accomplish this goal and look forward to receiving proposals to help all children achieve their potential.

The Live Your Dream Awards, sponsored by Soroptimist International of the Americas, empower women by providing vital monetary assistance for their education and training. Each year, over $3 million is awarded to more than 2,300 women who are the primary financial support for their families. This initiative supports those overcoming significant challenges like poverty and domestic violence, ensuring they have the resources to achieve their dreams and live fulfilling lives.

The Pathways to Enable Secure Open-Source Ecosystems (PESOSE) program, funded by the National Science Foundation, aims to transform open-source research into sustainable ecosystems that tackle national and societal challenges. This initiative promotes innovation across various sectors, including AI and cybersecurity, by fostering strong governance and broad user engagement. PESOSE invites proposals to establish and enhance open-source ecosystems, ensuring their safety, security, and effectiveness in meeting emergent needs.

The Bear Paw Resort Scholarship, offered by the Community Foundation for the Fox Valley Region, supports graduating seniors from White Lake High School who plan to pursue post-secondary education. With over $2 million available for scholarships in 2025, this initiative aims to empower students in their educational journeys. The scholarship is designed to assist with tuition costs, payable after the completion of the first semester, thereby encouraging academic success and community development.

The National Center for Construction Safety and Health Research and Translation (U54) aims to enhance worker safety in the construction industry through innovative research and intervention strategies. By fostering partnerships and focusing on evidence-based solutions, the Center will address critical safety and health challenges faced by construction workers. The initiative aligns with NIOSH's strategic objectives, promoting collaboration among academic institutions and organizations to improve health outcomes and reduce the occupational health burden in this vital sector.

The National Institute on Aging (NIA) is set to issue a Notice of Funding Opportunity (NOFO) for randomized controlled trials examining the long-term effects of nutritional interventions on risk factors for age-related chronic conditions. This initiative seeks to enhance understanding of how various dietary practices can influence health throughout the life span, emphasizing the need for studies with at least five years of follow-up. Researchers are encouraged to prepare collaborative proposals in response to this upcoming funding opportunity.

The Raftelis Leadership Scholarship, offered by the American Water Works Association, supports undergraduate and graduate students pursuing a consulting career in water utilities. With a value of $5,000, this scholarship aims to foster relationships with diverse, promising students who demonstrate leadership and strong academic performance. Applicants from various academic backgrounds, including business and finance, are encouraged to apply, emphasizing initiative and a desire to contribute positively to the community.

The Wold Foundation Grant, established in 1985, aims to support charitable, scientific, literary, and educational projects primarily benefiting Wyoming citizens and youth. It prioritizes initiatives in education, human services, cultural activities, healthcare, and scientific endeavors that promote conservation and outdoor recreation. Eligible organizations must be 501(c)(3) classified and operate in the U.S. The foundation does not fund individuals or projects that discriminate based on sex, age, or religion.

The NIH Director’s Transformative Research Award supports individual scientists or groups of scientists proposing bold, groundbreaking, exceptionally innovative, original, and/or unconventional research with the potential to create new scientific paradigms, establish entirely new and improved clinical approaches, or develop transformative technologies. Applications in any area within the biomedical sciences are welcome. No preliminary data are required. Projects must clearly demonstrate, based on the strength of the logic, a compelling potential to produce a major impact in a broad area of relevance to the NIH. The NIH Director’s Transformative Research Award is a component of the High-Risk, High-Reward Research (HRHR) Program of the NIH Common Fund.

The Institute of Education Sciences (IES) offers the Statistical and Research Methodology in Education grant (84.305D) to enhance education research through improved statistical methods and tools. This program invites applications focused on Core Grants for developing new methodologies or Toolkits for compiling existing research into user-friendly resources. The initiative aims to ensure these products are rigorously tested and disseminated widely to support effective education research practices.

The Institute of Education Sciences (IES) supports state agencies in utilizing their longitudinal data systems to inform educational policies and program decisions. This grant aims to enhance access to high-quality education and improve academic performance among learners. By empowering local education agencies with data-driven insights, IES fosters evidence-based practices that can lead to significant advancements in educational outcomes. This initiative is essential for shaping effective education strategies across states.

The NIH Instrumentation Grant Program for Resource-Limited Institutions supports the acquisition of advanced scientific instruments. This initiative aims to bolster biomedical research capabilities and educational opportunities at institutions that typically receive limited NIH Research Project Grant funding. By facilitating access to modern technology, the program enhances research quality and fosters innovation in healthcare and related fields.

The U.S. Department of Energy (DOE) plans to issue a Notice of Funding Opportunity (NOFO) titled "Accelerating Scale-up and Pre-piloting of Emerging Chemical Technologies (ASPECT)." This initiative aims to support financial assistance applications from entities focusing on innovative chemical technologies that enhance supply chain resiliency and reduce costs. The program seeks to advance the production of chemicals from alternative and waste feedstocks, fostering domestic manufacturing and improving environmental safety.

The National Institutes of Health (NIH) is set to announce a Notice of Funding Opportunity (NOFO) for multi-site investigator-initiated clinical trials. This initiative aims to support a range of clinical trials addressing efficacy and implementation research. The funding mechanism includes a two-phase approach (UG3/UH3), with a total award duration of up to seven years. Investigators are encouraged to prepare proposals that demonstrate scientific rationale and operational plans for these important studies.

The Cellular Senescence Network (SenNet) aims to establish a Data Coordination and Integration Center (DCIC) to enhance data management and accessibility within the NIH Common Fund. This initiative focuses on the submission, harmonization, and dissemination of SenNet-generated data, ensuring high-quality integration and usability. The DCIC will support both Stage 1 and Stage 2 outputs, fostering organizational outreach activities and promoting cross-study comparability through robust data infrastructure and tools.

This Request for Information (RFI) seeks input on the urgent need for gigawatt-scale electricity generation and transmission due to rapid demand growth from data centers and advanced manufacturing. The U.S. electric grid faces significant challenges, including limited capacity and aging infrastructure, which could hinder timely interconnection of new energy sources. Stakeholders are invited to provide feedback on overcoming regulatory and operational barriers to meet this escalating demand.

The Alvah H. and Wyline P. Chapman Foundation offers grants to support charitable, educational, and community-focused initiatives, primarily in Florida and Georgia. Eligible applicants must be IRS-recognized 501(c)(3) organizations. The foundation prioritizes projects that address children's welfare, education, multicultural understanding, substance abuse prevention, and homelessness. Grants typically do not exceed $15,000, and proposals must be endorsed by a Foundation Director. Interested parties should submit a Letter of Inquiry for consideration.

The NIH Director's Early Independence Award encourages exceptional early-career researchers to embark on independent research immediately after completing their doctoral degree or clinical training. This initiative accelerates the transition to independent research careers while supporting innovative projects across all areas of biomedical sciences. It is part of the NIH Common Fund's High-Risk, High-Reward Research program, aiming to foster groundbreaking discoveries.

The NIH Director's Pioneer Award Program aims to support exceptionally creative scientists who propose innovative research projects with the potential to significantly impact biomedical sciences. The program encourages bold ideas that diverge from existing research trajectories and welcomes applications across all areas of the biomedical field. As part of the High-Risk, High-Reward Research Program, this award fosters pioneering efforts that may lead to transformative advancements in health and medicine.

The ACS Local Section Innovative Project Grant Program aims to empower local sections of the American Chemical Society to devise and execute innovative projects that enhance community engagement and chemistry literacy. By fostering collaboration and inclusiveness, this program encourages sections to implement new initiatives inspired by successful practices from other groups. The goal is to strengthen member involvement and promote sustainable activities that contribute positively to the community's scientific culture.

The NSF SBIR/STTR programs are launching a pilot emphasis on advancing scientific instrumentation and enabling technologies to drive innovation and economic growth in the U.S. This initiative supports startups and small businesses developing critical scientific equipment and platforms, with funding opportunities up to $2 million for R&D. By prioritizing next-generation instrumentation, NSF aims to enhance the scientific enterprise and foster breakthroughs essential for the future of AI-driven discoveries and broader scientific advancements.

The Senior Chemists Mini Grant for Local Sections, offered by the American Chemical Society, is designed to support local events that engage senior members in innovative activities. Grants are available on a first-come, first-serve basis, and funding can be used for various events including recognition luncheons, mentoring for undergraduates, collaborative activities with younger chemists, and community support events such as science fairs.