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Best Seed Grants for Nonprofits in Puerto Rico

Find the perfect Seed grants for nonprofits in Puerto Rico on Instrumentl. 9,000+ Seed grants for nonprofits in Puerto Rico in the United States.

9,000+

Available grants

$2.55B

Total funding

$5K

Median grant

9,000+ grants
$2.55B total
$5K median

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8,956 Results based on applied filters

NCI Pathway to Independence Award for Early-Stage Postdoctoral Researchers (K99/R00 - Independent Clinical Trial Required)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Up to US $249,000
The NCI Pathway to Independence Award (K99/R00) supports early-stage postdoctoral researchers transitioning to independent faculty positions. This funding opportunity encourages talented individuals with clinical or research doctoral degrees to lead independent clinical trials. Applicants should aim to foster research careers in cancer control, prevention, and data sciences. This initiative provides essential support during the transition from mentored positions to independent research roles, enhancing the pool of independent investigators in cancer research.
Medical Education & Professional Training Biology Science +2 more

Air Dominance Broad Agency Announcement (BAA)

US DOD: Dept. of the Air Force, Materiel Command
Federal Government
American Samoa, Guam +4 more
Up to US $750,000,000
The Air Dominance Broad Agency Announcement (BAA) invites proposals for research aimed at enhancing national security through scientific study and experimentation. Managed by the Air Force Research Laboratory, this unrestricted acquisition encourages small businesses to participate. Proposals must demonstrate substantive research results and comply with federal regulations, ensuring a competitive selection process. The BAA supports exploratory and advanced development programs, with a focus on practical applications and potential experimental testing.
Emerging Technology Development Domestic / Homeland Security Aerospace Engineering +1 more

Building Communities of Recovery (363810)

Substance Abuse and Mental Health Services Adminis
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The Building Communities of Recovery program aims to enhance access to long-term recovery support for individuals facing substance use disorders and co-occurring mental health issues. By empowering organizations to mobilize community resources, this initiative fosters a collaborative environment that promotes sustained recovery. Funded by the Substance Abuse and Mental Health Services Administration, the program emphasizes the importance of community connections in the recovery process, ensuring that individuals receive the support they need to thrive.
Community Services Mental Health & Psychiatric Diseases Addiction & Substance Use Disorders +1 more

NCI Pathway to Independence Award for Early-Stage Postdoctoral Researchers (K99/R00 - Independent Clinical Trial Not Allowed)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Up to US $249,000
The NCI Pathway to Independence Award (K99/R00) supports early-stage postdoctoral researchers aiming to transition to independent faculty positions. It encourages candidates with doctoral degrees in research or clinical fields to apply, particularly those in cancer control and prevention. This funding opportunity facilitates a quick shift from mentored research to independent careers, providing essential support for awardees to establish competitive research programs without leading their own clinical trials.
Medical Education & Professional Training Biology Science +2 more

Small Business Innovation Research Program (SBIR) Phase II (363967)

US HHS: Administration for Community Living (ACL)
Federal Government
American Samoa, Guam +4 more
US $280,000 - US $287,500
The Small Business Innovation Research Program (SBIR) Phase II aims to enhance technological innovation in the private sector, focusing on improving the lives of individuals with disabilities through research and development. Administered by the US HHS Administration for Community Living, this program supports small businesses in addressing the needs of these individuals. Grants are available for a 24-month project period, allowing projects to expand upon Phase I results to achieve greater commercial application and societal impact.
Disability Care & Services Medical Rehabilitation Emerging Technology Development +1 more

Authority to Accept Unsolicited Proposals for Research Partnerships Notice of Intent (NOI)

US HUD: Office of Policy Development and Research (PD&R)
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The U.S. Department of Housing and Urban Development (HUD) is inviting eligible organizations to submit unsolicited research proposals targeting key areas like housing affordability and homelessness. This initiative aims to foster high-quality research that informs housing policies and programs. Projects must secure matching funds of at least 50% of the total cost and align with HUD's research priorities to qualify for cooperative agreements, ensuring ongoing collaboration throughout the research process.
Community Services Equitable & Affordable Housing

Affordable Rural Cooperative (ARC) Energy Program

Rural Utilities Service
Federal Government
American Samoa, Guam +4 more
Up to US $20,000,000
The Affordable Rural Cooperative (ARC) Energy Program, initiated by the Rural Utilities Service (RUS), aims to enhance rural electric systems through substantial funding of approximately $175 million. This initiative focuses on increasing emission-free nuclear power and improving transmission infrastructure efficiency, promoting long-term reliability and affordability. Eligible entities include electric cooperatives serving rural areas and their subsidiaries. The program aligns with the Inflation Reduction Act (IRA) to achieve significant reductions in greenhouse gas emissions, thus fostering a sustainable energy future.
Energy Rural Development Public Infrastructure +1 more

Museums for America (2027)

Institute of Museum and Library Services (IMLS)
Federal Government
American Samoa, Guam +7 more
US $5,000 - US $350,000
The Museums for America (MFA) program, funded by the Institute of Museum and Library Services (IMLS), supports museums across the nation in enhancing their educational programs, community partnerships, and collection stewardship. This initiative aims to serve diverse audiences through experiential learning, address community needs, and ensure the proper management of collections. By investing in museums of all sizes, the MFA program plays a vital role in preserving America's cultural heritage for future generations.
Art & Culture Community Culture & Heritage Education +2 more

National Leadership Grants for Museums (2027)

Institute of Museum and Library Services (IMLS)
Federal Government
American Samoa, Guam +7 more
US $50,000 - US $750,000
The National Leadership Grants for Museums, offered by the Institute of Museum and Library Services, support innovative projects addressing critical needs in the museum sector. These grants aim to enhance museum services for the public by fostering the development and replication of effective practices, tools, and collaborations, particularly leveraging new technologies. Eligible projects can significantly advance the professional field, ensuring museums remain vital community resources.
Art & Culture Community Culture & Heritage Community Development & Revitalization +2 more

Pilot Projects Investigating Understudied Proteins Associated with Rare Diseases (R03 Clinical Trial Not Allowed) (356879)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Up to US $100,000
This funding opportunity invites applications for pilot projects focused on understudied proteins linked to rare diseases. The goal is to generate preliminary data and tools related to these proteins, which belong to druggable families with known rare disease associations. By supporting innovative research, this initiative aims to facilitate the characterization of these proteins, ultimately contributing to advancements in understanding and treating rare diseases.
Human Genome & Genetics Rare Diseases

Advanced Rehabilitation Research Training (ARRT) Program - Health and Function (363965)

US HHS: Administration for Community Living (ACL)
Federal Government
American Samoa, Guam +4 more
US $245,000 - US $250,000
The Advanced Rehabilitation Research Training (ARRT) Program, funded by the US HHS: Administration for Community Living, aims to enhance the capabilities of individuals with advanced degrees in conducting high-quality research focused on health and function outcomes for people with disabilities. The program offers advanced training opportunities over a 36-month period, specifically targeting rehabilitation researchers, including those with disabilities, to foster multidisciplinary approaches in disability and rehabilitation research.
Medical Rehabilitation Medical Education & Professional Training Disability Rights & Justice

Jazz Road Tours Grants

South Arts, Inc.
Private
American Samoa, Guam +5 more
Up to US $15,000
Jazz Road Tours Grants provide financial support for emerging and mid-career jazz artists to develop tours across communities in the U.S. Grants up to $15,000 facilitate three-to-six site tours, focusing on underserved areas. This program, funded by the Doris Duke Charitable Foundation and the Mellon Foundation, aims to enhance artists' income opportunities while promoting jazz in diverse venues. Applications are encouraged from individual artists, with deadlines throughout 2024 and 2025 for various tour periods.
Music Festivals

Catalyze Product Definition Medical Device prototype design/testing and disease target identification and assay development (R61/R33 - Clinical Trial Not Allowed)

National Institutes of Health
Federal Government
American Samoa, Guam +4 more
Up to US $4,466,000
The NHLBI Catalyze program aims to transition basic science discoveries into effective treatments for diseases under the NHLBI mission. This initiative supports early-stage product definition, prototype design, and assay development for HLBS disorders. The R61 phase focuses on initial designs and experimental setups, while the R33 phase extends support for prototype testing and user feedback. Successful completion prepares products for in vivo testing, enhancing health and societal outcomes with NIH and other support.
Respiratory Diseases & Systems Sleep Medical Technology, Devices, and Equipment

Integration of Imaging and Fluid-Based Tumor Monitoring in Cancer Therapy (R01 Clinical Trial Optional) (357003)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Up to US $2,500,000
The Integration of Imaging and Fluid-Based Tumor Monitoring in Cancer Therapy (R01 Clinical Trial Optional) aims to enhance cancer treatment by integrating imaging and liquid biopsy assays. This initiative, led by the National Cancer Institute (NCI), encourages grant applications focused on assessing therapy responses and resistance emergence in patients. Key deadlines for submissions span from February 2025 to January 2028, providing ample opportunities for researchers to contribute to this vital area of cancer research.
Cancer / Oncology Biomedical Imaging

DoW Bone Marrow Failure, Investigator-Initiated Research Award

US DOD: U.S. Army Medical Command
Federal Government
American Samoa, Guam +4 more
Up to US $1,250,000
The DoW Bone Marrow Failure Investigator-Initiated Research Award supports innovative research aimed at advancing the understanding and treatment of bone marrow failure. This funding opportunity encourages applications for translational and clinical studies, requiring preliminary data to strengthen proposals. Unique features include the ability for a partnering Principal Investigator to contribute to the research, thereby fostering collaboration while maintaining a focus on significant advancements in patient care.
Skeletal Diseases Myeloma

DoW Bone Marrow Failure, Idea Development Award

US DOD: U.S. Army Medical Command
Federal Government
American Samoa, Guam +4 more
Up to US $800,000
The DoW Bone Marrow Failure Idea Development Award supports innovative, high-impact research aimed at understanding and curing bone marrow failure diseases. This grant is available to both Established Investigators and Early-Career Investigators, with no preliminary data required for applications. Reviewers assess proposals based on specific criteria tailored to the investigator's career stage. The focus is on achieving interpretable results that contribute significantly to the field.
Skeletal Diseases Myeloma

Craft Artists Emergency Relief Grant

Craft Emergency Relief Fund Inc
Private
American Samoa, Guam +4 more
US $1,000
The Craft Artists Emergency Relief Grant provides $3,000 to U.S.-based individual craft artists aged 18 and older who are facing recent, unforeseen emergencies. Established by the Craft Emergency Relief Fund (CERF+) in 1985, this grant aims to empower artists during critical times, allowing them to use the funds as needed for recovery. Applications are accepted on a rolling basis, ensuring timely support for artists in distress.
Folk Art / Traditional Art Visual Arts Textile & Fiber Arts

OJJDP FY 2026 Second Chance Act Youth Reentry Program

US Department of Justice: Bureau of Justice Assistance
Federal Government
American Samoa, Guam +4 more
Up to US $750,000
The OJJDP FY 2026 Second Chance Act Youth Reentry Program aims to provide critical support for moderate- to high-risk youth transitioning back into their communities after confinement. This funding opportunity encourages collaboration among state agencies, local governments, Tribes, and community organizations to deliver comprehensive reentry services and assist youth in overcoming challenges related to recidivism. Applications are due by November 9, 2026, at 8:59 p.m. ET.
Youth Services Crime & Justice Youth Development & Leadership

Catholic School Leadership Development Grant

Catholic Extension
Association/Society
Acadia Parish, Louisiana, Accomack County, Virginia +994 more
Unspecified amount
The Catholic School Leadership Development Grant Program aims to cultivate and retain promising leaders within the Catholic school system. In partnership with Loyola Marymount University, this initiative offers a graduate-level online Certificate in Catholic School Administration, covering 80% of tuition costs and providing funding for essential travel. The one-year program focuses on mission effectiveness, operational management, and instructional leadership, requiring participants to serve two years in their diocese post-completion, thereby enhancing local educational leadership.
Education - K through 12 Catholicism Religious / Theological Education

NIDCR Drug, Biologic, Device and/or Procedure Intervention Clinical Trial Planning and Implementation Cooperative Agreement (UG3/UH3 Clinical Trial Required)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The NIDCR Drug, Biologic, Device and/or Procedure Intervention Clinical Trial Planning and Implementation Cooperative Agreement (UG3/UH3) is designed to support clinical trial planning and implementation for dental, oral, and craniofacial conditions. This funding opportunity encourages applications that propose innovative research strategies within the NIDCR mission. Key deadlines span from February 2025 to January 2028, with emphasis on milestone-driven planning phases leading into possible clinical trial phases.
Dental Health Pharmacology Drug Safety +1 more

OJJDP FY 2026 Internet Crimes Against Children (ICAC) Task Force Program Support

US DOJ: Office of Juvenile Justice & Delinquency Prevention (OJJDP)
Federal Government
American Samoa, Guam +4 more
Up to US $1,200,000
The OJJDP FY 2026 Internet Crimes Against Children (ICAC) Task Force Program Support aims to fortify a national network of 61 multiagency task forces dedicated to combating child sexual exploitation facilitated by technology. This funding opportunity enhances training, prevention, and outreach efforts while fostering collaboration among law enforcement entities. Applications are due in JustGrants by November 9, 2026, at 8:59 p.m. ET, ensuring timely support for critical initiatives to protect children.
Youth Services Crime & Justice Crime Victim Services +1 more

Women's Initiative for Screening and Health (WISH) (361882)

US HHS: Health Resources & Services Administration (HRSA)
Federal Government
American Samoa, Guam +4 more
Up to US $1,000,000
The Women's Initiative for Screening and Health (WISH) aims to enhance women's health by improving access to preventive services. It focuses on updating HRSA-supported guidelines, increasing awareness of these guidelines, and promoting their adoption in clinical practice. By collaborating with healthcare providers, academic institutions, and patient organizations, WISH strives to implement a comprehensive strategy that benefits women's health across their lifespan.
Women's Health Preventative Healthcare

Clinical Trials in Organ Transplantation in Children and Adults

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The National Institute of Allergy and Infectious Diseases (NIAID) is advancing organ transplantation outcomes through the Clinical Trials in Organ Transplantation in Children and Adults (CTOT-CA) program. This initiative supports multicenter clinical trials and mechanistic studies related to heart, lung, kidney, liver, and intestinal transplants, as well as non-hematopoietic cellular transplantation. By exploring immune mechanisms and innovative therapies, the program aims to enhance the success and efficacy of organ transplantation.
Infectious & Parasitic Diseases Organ And Tissue Banks

Southeastern Region- Colleen Callahan Professional Development Award

Costume Society of America
Association/Society
Alabama, Arkansas +12 more
US $250 - US $1,000

About

The Costume Society of America (CSA) is a 501(c)(3) non-profit organization founded on March 23, 1973, and incorporated in the state of New York on September 12, 1973. CSA serves it members, and promotes its goals with national symposia and publications including the journal Dress and its monthly electronic newsletter CSA e-News.

The organization began forming regional groups in 1978. There are six regional groups in the United States and Canada, and one international group. Individual regions hold annual meetings, sponsor programs and publish newsletters.

Our Mission

The Costume Society of America fosters an understanding of appearance and dress practices of people across the globe through research, education, preservation, and design. Our network of members studies the past, examines the present, and anticipates the future of clothing and fashion.

Colleen Callahan Professional Development Award

Members are invited to apply for the Professional Development Grant offered by Southeastern Region of the Costume Society of America. Awards will be made at a minimum of $250 with the total award not to exceed $1000. Your project may be on any aspect of costume, any technical skill, or any administrative expertise which will further the mission and purposes of the Costume Society of America. The grant money may be applied to research, a course, workshop fees, or travel.

Visual Arts Textile & Fiber Arts Artist Training & Development

DoW Military Burn, Discovery Award

US DOD: U.S. Army Medical Command
Federal Government
American Samoa, Guam +4 more
Up to US $200,000
The FY26 Military Burn Research Program (MBRP) Discovery Award aims to support groundbreaking research in combat-relevant burn care. This award encourages innovative and exploratory studies that provide new insights and foundational data for future clinical research. The focus is on novel approaches that lay the groundwork for scientific advancements and product development in burn care, ensuring robust preliminary data generation for subsequent research initiatives.
Burn Care

Translational Transplantation Tolerance Cooperative Study Group

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The Translational Transplantation Tolerance Cooperative Study Group, supported by the National Institute of Allergy and Infectious Diseases, aims to advance transplant tolerance strategies that promote long-term graft survival without lifelong immunosuppression. This initiative focuses on developing, optimizing, and evaluating methods to induce immune tolerance in allogeneic transplants through collaborative efforts across multiple centers, utilizing translationally relevant models to ensure effective outcomes.
Infectious & Parasitic Diseases Organ And Tissue Banks

Collaborative Network for Clinical Research on Immune Tolerance

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The National Institute of Allergy and Infectious Diseases (NIAID) is advancing research on immune tolerance through its Collaborative Network. This program aims to clarify the mechanisms of immune tolerance and develop interventions for related diseases, including transplant rejection and autoimmune disorders. Key objectives include conducting clinical trials on tolerogenic strategies and refining immune assays. This initiative is supported by regulations under the Public Health Service Act, ensuring a structured approach to improving patient outcomes.
Infectious & Parasitic Diseases Immune System Diseases

Seed Grants for Nonprofits in Puerto Rico Highlights

Looking for seed grants for nonprofits in Puerto Rico?


Read more about each grant below or start your 14-day free trial to see all seed grants for nonprofits in Puerto Rico recommended for your specific programs.

Last updated: October 5, 2026. Next update: November 1, 2026.

Grant Insights : Seed Grants for Nonprofits in Puerto Rico

Grant Availability

How common are grants in this category?

Quite common — grants in this category are more prevalent than in others.

800+ Seed grants for nonprofits in Puerto Rico grants for nonprofits in the United States, from private foundations to corporations seeking to fund grants for nonprofits.

500+ Seed grants for nonprofits in Puerto Rico over $25K in average grant size

400+ Seed grants for nonprofits in Puerto Rico over $50K in average grant size

16 Seed grants for nonprofits in Puerto Rico supporting general operating expenses

500+ Seed grants for nonprofits in Puerto Rico supporting programs / projects

600+ Grants on Instrumentl focused on Food Access & Hunger

1,000+ Grants on Instrumentl focused on Workforce Preparation & Job Readiness

Grant Deadline Distribution

Over the past year, when are grant deadlines typically due for Seed grants for Nonprofits in Puerto Rico?

Most grants are due in the first quarter.

Q1
31.5%
Q2
23.7%
Q3
19.8%
Q4
25.0%

Typical Funding Amounts

What's the typical grant amount funded for Seed Grants for Nonprofits in Puerto Rico?

Grants are most commonly $318,750.

$375 $375 Min.
$318,750 $318.8 K Median
$1,385,019 $1.4 M Average
$80,000,000 $80 M Max.

Average Grant Size

What's the typical amount funded for Puerto Rico?

Grants are most commonly $104,638.

$104,638

Total Number of Grants

What's the total number of grants in Seed Grants for Nonprofits in Puerto Rico year over year?

In 2024, funders in Puerto Rico awarded a total of 1,758 grants.

2022 1,942

2023 1,805

2024 1,758

Top Grant Focus Areas

Among all the Seed Grants for Nonprofits in Puerto Rico given out in Puerto Rico, the most popular focus areas that receive funding are Education, Human Services, and Human Service Organizations.

1. Education

2. Human Services

3. Human Service Organizations

Funding Over Time

How is funding for Seed Grants for Nonprofits in Puerto Rico changing over time?

Funding has increased by 15.38%.

2022 $135,836,997

2023 $159,254,276
17.24%

2024 $183,744,801
15.38%

Puerto Rico Counties That Receive the Most Funding

How does grant funding vary by county?

San Juan County, Dorado County, and Loiza County receive the most funding.

County Total Grant Funding in 2024
San Juan County $85,833,046
Dorado County $27,296,199
Loiza County $11,736,039
Bayamon County $11,338,985
Vega Alta County $9,404,211