Best Small Grants for Nonprofits in Puerto Rico

The OVC FY 2026 Services for Victims of Human Trafficking aims to enhance victim service programs across the United States. This initiative supports victims by providing critical services to address their diverse needs, including mental health support and assistance with legal challenges. By funding comprehensive programs, the Office for Victims of Crime seeks to combat human trafficking effectively and promote recovery for affected individuals, ensuring their rights and well-being are prioritized.

The RNomics Outreach and Coordination (ROC) Center, established by the NIH Common Fund, aims to enhance understanding of RNA molecules through integrated analysis. This center will serve as a hub for data management and community engagement, developing a central data portal, supporting data standards, and coordinating consortium-wide analyses. By fostering collaborations and providing training, the ROC Center seeks to ensure the long-term availability of essential RNomics resources, ultimately advancing health and disease research.

The OVC FY 2026 Integrated Services for Minor Victims of Human Trafficking aims to enhance the availability and quality of services for minor victims. This funding opportunity reflects the commitment of the U.S. Department of Justice to combat human trafficking and provide critical resources to support law enforcement and service organizations. Applications must be submitted in JustGrants by October 5, 2026, ensuring timely access to vital funding for enhancing victim support services.

The BK℠ Scholars Program, initiated by the Burger King Foundation, provides scholarships ranging from $1,000 to $60,000 to support high school seniors, restaurant team members, and their dependents in pursuing post-secondary education. Established in 2000, the program aims to empower individuals through education, encouraging leadership and civic engagement while also offering emergency assistance to employees facing hardships. This initiative reflects the Foundation's commitment to education and community empowerment across North America.

The Indian Environmental General Assistance Program (GAP), administered by the U.S. Environmental Protection Agency (EPA), provides crucial funding to tribal governments and intertribal consortia for developing environmental protection programs. Since 1992, GAP has focused on remediation of pollutants and, more recently, supports climate adaptation initiatives. The program emphasizes tribal sovereignty while aiding in capacity building, policymaking, and establishing joint EPA-Tribal Environmental Plans to effectively address environmental challenges faced by tribal communities.

The NIH HEAL Initiative PainCare Clinician Training Program (PCTP) aims to develop a new generation of independent investigators in patient-oriented research focused on pain management. This K23 award provides essential funding to support early-career researchers, enabling them to establish independent research programs aligned with the NIH HEAL Initiative. Key application deadlines span from October 2024 to June 2027, ensuring opportunities for renewals and resubmissions. This program is vital for advancing pain management research.

The E.B. Henderson Award, presented by SHAPE America, honors minority members who have demonstrated exceptional commitment to scholarship, mentorship, and advocacy for ethnic minorities within health and physical education. Established in 1885, SHAPE America serves over 200,000 professionals, promoting high-quality education standards. The award recognizes individuals who have significantly contributed to increasing the participation of underserved populations in the field. Limited to two awards annually, it highlights the importance of diversity and inclusion in health education.

The Deana and Paul Strunk Military Veterans Scholarship Program offers financial aid ranging from $2,500 to $5,000 for veterans and military dependents pursuing geoscience degrees at accredited institutions. This program facilitates educational opportunities and aids in the transition of veterans to civilian careers. Eligible applicants must provide proof of military service and demonstrate financial need, along with academic excellence and a commitment to geoscience. This initiative aims to support both active service members and veterans in their educational journeys.

The HEAL Initiative Whole Joint Health Program aims to advance research on the biological mechanisms of joint pain by exploring the interactions of various tissues within the joint. This innovative program will support clinical studies that focus on non-pharmacological interventions to enhance healing and improve quality of life for individuals suffering from chronic joint pain. By fostering a comprehensive understanding of joint health, the initiative aligns with the NIH's broader goals to reduce chronic pain and opioid dependency.

The Rural Housing Preservation Grant (HPG) program, administered by the USDA's Rural Housing Service, offers funding to support very low- and low-income homeowners in rural areas. This program also assists rental property owners and cooperative housing complexes in making necessary repairs and renovations, ensuring that housing remains accessible to those in need. Preapplications must be submitted by September 8, 2026, to comply with regulatory requirements.

The Gerber Foundation offers grants for pediatric research focusing on environmental hazards that affect infants and young children. The foundation seeks projects that provide innovative solutions to health and nutritional challenges faced by this vulnerable population. Grant applications are encouraged from organizations recognized as tax-exempt under Internal Revenue Code 501(c)(3), with an emphasis on research that produces new information to improve practices in infant care and development.

The AAUW Community Action Grants provide up to $75,000 to support nonprofits and educational institutions that empower girls in grades K–12 to succeed in STEM fields. By fostering hands-on learning, mentorship, and family involvement, these grants aim to build confidence and skills among girls, especially those from underrepresented communities. AAUW believes that immersive STEM environments and relatable role models can inspire lasting interest and help close the gender gap in leadership and careers.

The Equitable Excellence Scholarship® Program, administered by Scholarship America, provides 100 annual scholarships of $5,000 to high school seniors with financial need. This program aims to support students as they pursue higher education, with scholarships renewable for up to four years, totaling $20,000 per recipient. Eligible applicants must demonstrate ambition and reside in the U.S. This initiative promotes educational access and equity, celebrating 23 years of empowering students to achieve their dreams.

The Advancing Research Careers (ARC) Predoctoral to Postdoctoral Transition Award (F99/K00) supports late-stage graduate students from diverse backgrounds in transitioning to postdoctoral positions. This phased award aims to facilitate doctoral dissertation completion and subsequent career development in biomedical research. Participants will engage in mentoring, networking, and professional development activities, preparing them for impactful careers that often require postdoctoral training. Key deadlines for applications span from February 2025 to January 2028.

The National Cancer Institute's Youth Enjoy Science Research Education Program (R25) aims to enhance educational opportunities in biomedical research for underrepresented students in grades 6-12 and undergraduates. By fostering diverse participation, the program seeks to inspire interest in cancer research careers and strengthen essential research skills through hands-on experiences. This initiative aligns with the NIH's mission to support education and training in health sciences, ultimately contributing to a more inclusive research community.

The NIH Common Fund is launching the RNomics program to advance RNA research through innovative technologies. This initiative focuses on developing tools for comprehensive analysis of RNA molecules, addressing current methodological limitations. Key priorities include sequencing RNA, detecting modifications, and studying RNA function across various biological contexts. The program encourages high-risk, early-stage projects that demonstrate potential for significant impact. Successful Phase 1 projects may transition to Phase 2, aimed at delivering validated resources for the research community.

The RNomics Technology Enhancement Centers, supported by the NIH Common Fund, aim to enhance tools for comprehensive RNA analysis, facilitating insights into health and disease. This initiative focuses on developing technologies for RNA sequencing, modification mapping, and functional testing. By fostering collaborations and strengthening existing resources, RTECs will advance the study of RNA molecules, ensuring broad community access to improved experimental and computational methods.

BASF Corporation, a leading chemical company based in Florham Park, New Jersey, is committed to charitable giving that aligns with its corporate social responsibility goals. The focus areas include science education, environmental sustainability, and health and safety. Donations are only made to eligible non-profit organizations under the U.S. Internal Revenue Code, ensuring that contributions support initiatives that enhance the quality of life in BASF communities and promote a sustainable future.

This grant opportunity from the NIH aims to enhance mechanistic research on precision probiotic therapies through a biphasic R61/R33 award mechanism. It encourages innovative studies to identify specific biological factors influencing probiotic responses, thereby improving clinical outcomes. The program supports up to five years of research, with the initial phase focused on discovering unique host characteristics and the second phase assessing improvements in probiotic efficacy through rigorous studies.

The Institutional Translational Research Training Program (T32) aims to prepare trainees for advancing basic research into clinical applications. This program focuses on developing essential skills in experimental design, statistical analysis, and effective science communication. Participants, including advanced predoctoral students and postdoctoral fellows, will engage in a two-year training program that fosters collaboration among neuroscientists and clinicians, ultimately equipping them to tackle basic research challenges and translate discoveries into viable therapies.

This funding opportunity aims to support innovative mechanistic research that enhances precision probiotic therapies. It encourages studies that identify person-specific features influencing probiotic responses, focusing on the variability among individuals. The goal is to develop strategies to improve probiotic clinical outcomes by understanding the biological patterns linked to probiotic effectiveness. Applications should demonstrate rigorous mechanistic studies and preliminary data supporting the correlation between host biology and probiotic response.

The Rural Residency Planning and Development (RRPD) Program enhances rural healthcare access by establishing sustainable residency programs for physicians. Focused on training in accredited rural settings, the program addresses physician shortages by providing start-up funding for various medical specialties, including family medicine and psychiatry. This initiative aims to ensure long-term sustainability through stable funding sources like Medicare and Medicaid, ultimately preparing physicians to serve rural communities effectively.

The FY 2027 State and Regional Primary Care Association (PCA) Cooperative Agreements aim to enhance the technical assistance provided to Health Center Program award recipients and look-alikes. This initiative focuses on improving access to preventive and primary health care, managing chronic diseases, and ensuring a capable health center workforce. By implementing value-based care strategies and leveraging data for operational improvements, the program seeks to support the health of vulnerable communities effectively.

The National Institute of Dental and Craniofacial Research (NIDCR) is inviting innovative research applications on the causal relationships between human behaviors and oral-systemic health impacts, particularly for people with chronic conditions. This funding opportunity encourages the exploration of biological, environmental, and psychosocial factors contributing to health outcomes. Projects should aim for translation into clinical trials to manage dental and craniofacial conditions effectively. Collaboration among diverse health experts is strongly encouraged.

The NIH HEAL Initiative PainCare Clinician Training Program (PCTP) offers Mentored Clinical Scientist Development Awards (K08) to nurture new independent investigators. This program is pivotal in providing early-career researchers with the necessary NIH support to establish their research programs in pain management. Key deadlines for applications span from October 2024 to June 2027, including provisions for renewals and resubmissions, ensuring ongoing support for innovative research in this critical area.

The SHAPE America: Mentor of the Year Award recognizes an exemplary role model committed to fostering student engagement in professional activities. Candidates must have a minimum of three years of membership in SHAPE America and serve as full-time faculty at a higher education institution. This award emphasizes mentorship through professional behavior, involvement in student projects, and providing academic guidance, ensuring that students are well-prepared for their future careers.

The Innovative Programs to Enhance Research Training (IPERT) initiative by the NIH aims to support innovative educational activities that enhance the skills of participants across various career stages in the biomedical research field. This program focuses on courses for skills development, mentoring activities, and curriculum or methods development, ensuring a robust structure for leadership, recruitment, and evaluation.