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The NIH invites applications to study environmental factors affecting animal research rigor and reproducibility. This initiative encourages core facilities and investigators to enhance scientific understanding through modern equipment that measures various biological and behavioral variables. Proposed research must align with NIH's mission, addressing critical processes impacting multiple organ systems. The goal is to improve the reliability of animal studies by systematically evaluating extrinsic influences in biological contexts.

This funding opportunity aims to enhance the development of a diverse workforce skilled in translational research related to Alzheimer's disease and related dementias. It supports institutional training programs at both predoctoral and postdoctoral levels, encouraging interdisciplinary approaches integrating data science and clinical research. By fostering knowledge in essential areas such as disease biology and drug discovery, this initiative aims to equip researchers with the skills necessary for impactful contributions in the field.

The Innovation Grants to Nurture Initial Translational Efforts (IGNITE) support the development of assays and screening processes to identify potential therapeutic agents for neurological disorders and non-opioid analgesics. Sponsored by the NIH, this initiative seeks to foster collaborations and projects that utilize innovative methodologies. Although applications are not currently being solicited, interested parties are encouraged to prepare meaningful proposals that align with the goals of the NIH Helping to End Addiction Long Term initiative.

The Innovation Grants to Nurture Initial Translational Efforts (IGNITE) program, supported by the National Institutes of Health, aims to fund pharmacodynamic and pharmacokinetic studies. These studies will assess the biological activity of therapeutic agents, including small molecules and biologics, for diseases prioritized by participating institutes. The initiative emphasizes the development of non-opioid analgesics with minimal addiction risks. Although applications are not currently solicited, this notice encourages potential applicants to prepare collaborative projects.

The NIDA Core "Center of Transformative Science" Grant Program aims to enhance research on substance use, addiction, and HIV by fostering collaboration among NIH-funded researchers. Centers are expected to innovate and extend existing research through shared resources and support for new investigators. This initiative encourages interdisciplinary work and aims to transform the scientific landscape by promoting data sharing and collaborative opportunities. Applications should focus on integrating research within a specific thematic framework to maximize impact.

The Intervention Research to Improve Native American Health (IRINAH), led by the National Institute on Drug Abuse, focuses on enhancing health outcomes in Native populations. It supports research to identify causes of health issues, develop and test effective interventions, and implement strategies that promote sustainability. Emphasizing community strengths, the initiative aims to rigorously evaluate solutions to reduce health disparities, ensuring interventions can be adapted and shared across diverse communities.

The NIH Mentored Patient-Oriented Research Career Development Award (K23) aims to enhance the career development of clinical doctoral degree holders dedicated to patient-oriented research. It supports individuals in their commitment to focus their research efforts on improving patient outcomes. The award has multiple application deadlines, including June 12, 2024, and October 12, 2024, among others, catering to various grant types, including standard, renewal, and AIDS-related applications.

The NIH Mentored Patient-Oriented Research Career Development Award (K23) is designed to support the career development of individuals with clinical doctoral degrees committed to patient-oriented research. Key deadlines for standard applications include June 12, October 12, and February 12 from 2024 to 2027. Renewal and AIDS-related grant applications also have specific deadlines. This initiative aims to enhance research focused on improving patient care.

The NIH Mentored Patient-Oriented Research Career Development Award (K23) aims to support healthcare professionals with a clinical doctoral degree in their pursuit of patient-oriented research. This award is essential for those committed to advancing their research careers, ensuring they focus on enhancing patient care. Key application deadlines for standard and renewal submissions span from June 2024 to February 2027, providing ample opportunity for interested candidates to apply.

The NIA Genetics of Alzheimer’s Disease Data Storage Site (NIAGADS) aims to create a secure, scalable cloud platform for genetic data related to Alzheimer’s disease. This initiative will enhance data accessibility, promote interoperability, and support rigorous research practices. By facilitating collaboration and providing robust analytical tools, the platform will maximize the scientific impact of AD/ADRD research, aligning with NIH goals for transparent and reproducible science, while addressing recommendations for broad access to high-value datasets.

The Northeast Sea Grant Consortium and NOAA’s Northeast Fisheries Science Center invite proposals to explore the interactions between fishing communities and offshore wind development in the U.S. Northeast. This initiative aims to enhance understanding of community resilience and economies, while fostering collaborative research that informs decision-making. Proposals should utilize qualitative and quantitative methods and involve at least one Co-PI from the six states of the NESGC, with a requirement for a 25% non-federal match.

The NIH Blueprint Initiative aims to enhance neuroscience research by funding the development and application of germline and somatic gene-editing techniques. This initiative builds on existing marmoset gene-editing frameworks and integrates New Approach Methodologies (NAMs) to improve understanding of human brain function and disease. High-priority areas include complex conditions like autism and schizophrenia. The initiative emphasizes the use of appropriate models to address critical questions in neuroanatomy, cognition, and behavior related to human brain health.

The NIH Support for Conferences and Scientific Meetings (R13) provides funding for high-quality conferences that align with public health and scientific missions. Key deadlines for applications include April 12, August 12, and December 12 for the years 2024 through 2026, with specific deadlines for AIDS-related grants as well. This funding opportunity aims to foster collaboration and dissemination of important research findings in relevant fields.

The Medical Scientist Training Program (MSTP) aims to cultivate a diverse group of physician-scientist leaders to address the nation's biomedical research needs. This program supports institutions in creating integrated dual-degree training that results in both medical and research doctorate degrees. By combining clinical practice with scientific research, MSTP graduates will advance health-related research, focusing on improving training effectiveness, alumni retention in research careers, and workforce diversity. NIGMS emphasizes comprehensive training elements for impactful careers.

The DoW Toxic Exposures Investigator Initiated Research Award aims to fund critical studies addressing diseases linked to military-related toxic exposures. This award supports a wide range of research phases, from basic laboratory investigations to translational research involving both animal models and human subjects. Projects may also explore New Approach Methodologies, enhancing our understanding and treatment options for affected individuals. By facilitating innovative research, this initiative seeks to improve patient care and outcomes.

The FY26 Toxic Exposures Research Program (TERP) Clinical Trial Award supports clinical trials aimed at addressing health issues from military-related toxic exposures. This initiative encourages collaboration through a Partnering Principal Investigator Option, enhancing interdisciplinary research efforts. Projects range from early-phase trials to large-scale studies, focusing on innovative treatments and management strategies for affected populations. The goal is to expedite the translation of research findings into effective clinical applications.

The DoW Toxic Exposures Translational Research Award aims to foster translational research that bridges military-related toxic exposure studies and clinical applications. This program encourages innovative collaborations by allowing for a Partnering Principal Investigator Option, enhancing interdisciplinary partnerships. By integrating basic science with clinical insights, the initiative seeks to expedite the development of impactful health care products and interventions to address toxic exposures faced by military personnel.

The U.S. Fish and Wildlife Service's Coastal Program offers vital technical and financial support for projects aimed at protecting and restoring fish and wildlife habitats in priority coastal ecosystems. Collaborating with conservation partners, the program ensures that all projects are scientifically sound and align with the missions of the Department of the Interior. Applicants must contact a local office for guidance before applying, ensuring projects meet strategic conservation goals.

The NIDCR Predoctoral to Postdoctoral Transition Award aims to enhance the diversity of the dental, oral, and craniofacial research workforce. This program supports exceptional graduate students from underrepresented backgrounds as they transition from PhD or dual degree programs (F99) to mentored postdoctoral positions (K00). Key deadlines for applications span from August 2024 to April 2027, ensuring ample opportunities for eligible candidates to apply.

The National Cancer Institute (NCI) is inviting applications for the Specialized Programs of Research Excellence (SPOREs) in Human Cancers for 2027-2029. This funding opportunity supports innovative translational research aimed at improving prevention, detection, and treatment of organ-specific cancers. Eligible projects may address related cancer types from the same organ system or focus on common biological mechanisms. The program emphasizes research that translates findings into clinical applications, with the goal of achieving a human endpoint during the grant period.

The Nutrition Obesity Research Centers (NORCs) program, funded by the National Institutes of Health, invites applications for core centers that enhance nutrition and obesity research. It supports research core services, pilot and feasibility programs, and enrichment activities, aiming to improve research efficiency and productivity. This funding opportunity encourages multidisciplinary approaches to tackle obesity and nutrition issues, ultimately contributing to a healthier population.

The NIH StrokeNet initiative invites applications for multi-site exploratory and confirmatory clinical trials targeting interventions for stroke prevention, treatment, and recovery. This includes biomarker validation studies and ancillary studies to enhance active research. Successful applicants will collaborate within the NIH StrokeNet framework, with support from the National Coordinating Center and Data Management Center to ensure efficient study implementation and robust statistical analysis. Key deadlines for application submissions span from March 2024 to November 2026.

The Autism Centers of Excellence R01 aims to advance research in autism through collaborative networks, enhancing the past 23 years of progress. This initiative encourages innovative methods and technologies, inviting experts to consider applying for future funding opportunities. Although applications are not currently solicited, potential applicants are urged to form meaningful collaborations. This funding opportunity reflects a commitment to improving research in autism, leveraging diverse scientific expertise to address critical challenges in the field.

The NIH R25 program aims to enhance inclusivity in research education by supporting activities that encourage individuals from diverse backgrounds to pursue careers in substance use and addiction sciences. This initiative focuses on skills development courses and research experiences, particularly targeting underrepresented groups in biomedical and behavioral sciences. Applications are due by 5:00 PM local time of the applicant organization, with optional Letters of Intent encouraged 30 days prior to the full proposal deadline.

The NINDS Exploratory Clinical Trials for Small Business (R41/R42) program supports Small Business Concerns in conducting investigator-initiated exploratory clinical trials. This funding opportunity emphasizes projects that align with the NINDS mission, evaluating diverse products including drugs, biologics, and devices. Only STTR Phase II and Fast-Track applications are eligible, fostering innovation in neurological disorder treatments. Applications are due by 5:00 PM local time, with optional Letters of Intent encouraged 30 days prior to the deadline.

The NINDS Exploratory Clinical Trials for Small Business (R43/R44 Clinical Trial Required) grant supports small businesses in conducting innovative clinical trials relevant to neurological disorders. This funding opportunity encourages investigator-initiated projects evaluating drugs, devices, and therapies aligned with NINDS goals. Applications are accepted only from SBIR Phase II and Fast-Track applicants, with a submission deadline of 5:00 PM local time. Letters of Intent are encouraged 30 days prior to the full proposal deadline.

The Miniaturization and Automation of Tissue Chip Systems (MATChS) initiative by the NIH aims to advance biomedical research through the development of automated tissue chip platforms. This program encourages small businesses to propose innovative technologies that enhance data acquisition and analysis while minimizing manual handling. Funded projects will create efficient, miniaturized systems vital for drug development and other research applications. Collaboration with NIH staff is expected to ensure milestones and commercial pathways are effectively established.