Best Rock County Grants for Nonprofits in Wisconsin

The National Institutes of Health (NIH) is continuing support for the Network for Excellence in Neuroscience Clinical Trials (NeuroNEXT), which focuses on clinical trials and biomarker validation studies for neurological disorders. This initiative aims to foster innovation in neurotherapeutics by providing essential infrastructure and expertise. The program encourages the establishment of Clinical Coordinating Centers (CCC) and Data Coordinating Centers (DCC) to enhance collaborative efforts. Note that applications are not currently being solicited.

The Undiagnosed Diseases Network (UDN) Clinical and Data Coordinating Center aims to enhance diagnosis and research for individuals with undiagnosed diseases. This initiative focuses on engagement, education, and innovative diagnostic approaches. The center will oversee recruitment, participant support, and data management while fostering collaboration among various stakeholders. NINDS seeks proposals demonstrating the necessary infrastructure and partnerships to ensure effective implementation of the UDN's mission and transfer successful diagnostic methods into mainstream healthcare.

The Undiagnosed Diseases Network (UDN) Diagnostic Research Innovation Center (DRIC), supported by NINDS, aims to enhance diagnostic capabilities for UDN participants. This initiative will foster collaboration among clinical networks and stakeholders to develop innovative diagnostic tools and strategies. The DRIC will also focus on the systematic evaluation of unresolved UDN cases, advancing genomic and non-genomic diagnostics, and discovering novel disease-associated genes. This forecast allows potential applicants to prepare and collaborate effectively for future projects.

The NIH Stroke Clinical Trials Network (StrokeNet) aims to enhance stroke treatment through regional clinical enrollment coordinating centers (RCCs). Supported by the National Institute of Neurological Disorders and Stroke (NINDS), this initiative promotes collaboration for clinical trials that focus on acute stroke treatment, prevention, and rehabilitation. While applications are not currently being solicited, this notice serves to prepare potential applicants for future opportunities in advancing stroke care.

The Undiagnosed Diseases Network (UDN) aims to enhance diagnostic excellence through multiple clinical Networks of Diagnostic Excellence (NODEs). These NODEs will operate as regional networks, leveraging partnerships with various healthcare facilities to provide participant-centered evaluations for complex conditions. They will also engage in research and training to improve diagnostic tools and strategies. This initiative encourages collaboration and aims to improve the overall experience and access for participants in need of specialized care.

The National Institutes of Health (NIH) is continuing its support for the NeuroNEXT initiative, which focuses on conducting clinical trials and biomarker validation studies for neurological disorders. This infrastructure aims to foster innovation and enhance the development of effective neurotherapeutics for both adult and pediatric populations. While applications for network clinical research sites are not currently being solicited, this notice allows potential applicants to prepare collaborative and responsive applications.

The Homeless Veterans' Reintegration Program (HVRP) aims to assist veterans experiencing homelessness by providing tailored employment services. This federal initiative focuses on helping veterans transition to stable employment through job training, case management, and connections to local supportive services. HVRP aligns with national priorities to enhance career outcomes for veterans, ensuring they receive the necessary tools and resources for sustainable employment and integration into the workforce.

The Native Public Health Resilience (NPHR) program is a new funding opportunity aimed at supporting Tribes and Tribal Organizations in delivering essential public health services. Sponsored by the Indian Health Service, this initiative seeks to bolster public health infrastructure and resilience within tribal communities, ensuring they have the necessary resources to address health challenges effectively. Eligible applicants will receive financial assistance to enhance their public health capabilities and improve community health outcomes.

The NIH Stroke Clinical Trials Network (StrokeNet) aims to enhance stroke treatment and recovery through a robust national infrastructure. Funded by the National Institutes of Health, this initiative focuses on clinical trials that evaluate innovative therapies for stroke patients and those at risk. The program is currently not soliciting applications but encourages the development of collaborations to support the national coordinating center and data management efforts, ultimately improving outcomes for individuals affected by stroke.

The NIDA Avenir Program aims to cultivate innovative leaders in addiction science by funding exceptional early stage investigators (ESIs) embarking on pioneering research. Launched in 2015, this initiative encourages high-risk, high-reward mechanistic studies related to Substance Use Disorders (SUDs) across diverse scientific domains. Applications from new investigators and those outside addiction research are welcomed, fostering interdisciplinary approaches that enhance understanding of SUD mechanisms. The program supports ESIs who may lack preliminary data but demonstrate potential for impactful contributions.

The BRAIN Initiative aims to advance innovative neurotechnologies by funding early-stage clinical studies for devices that record or stimulate the human central nervous system. This initiative encourages collaborations between clinical researchers and device manufacturers to facilitate groundbreaking studies. By addressing the challenges of obtaining safety and utility data, this program supports both non-invasive and significant risk devices, providing essential insights into their functionality and design. Applications are currently not being solicited, allowing time for meaningful project development.

The BRAIN Initiative, led by the NIH, aims to advance neurotechnologies at institutions with limited NIH funding. This funding opportunity encourages collaboration and knowledge transfer to integrate innovative neurotechnologies into research and training programs. While applications are currently not being solicited, potential applicants should start developing partnerships and projects in preparation for future submissions. This initiative will enhance the dissemination of BRAIN technologies and support novel research practices.

Stars, Stripes & Skilled Trades

General Motors invites eligible 501(c)(3) nonprofit organizations to submit proposals for Stars, Stripes & Skilled Trades, a workforce development initiative designed to support veterans, transitioning service members, and military-connected family members—including spouses—in building lasting careers in manufacturing, automotive, and skilled trades. GM is seeking scalable, results-driven programs that create clear pathways to quality careers while recognizing the experience and leadership that veterans and military families bring to American industry. 

We're looking for existing initiatives that:

• Serve career-transitioning service members, veterans, and military-connected family members
• Provide industry-recognized training, certifications, or credentials
• Connect participants to mentorships, quality jobs, and long-term career pathways in manufacturing, automotive technician roles, or skilled trades.

Grant Range

• $100,000 | $250,000 | $500,000

Mellon Foundation

The Andrew W. Mellon Foundation was established in 1969 to strengthen, promote, and defend the arts and humanities as essential to democratic societies. Throughout our history, Mellon has held true to our founding commitments, secure in our conviction that the arts and humanities are essential to the health of a multivocal and democratic society. From our earliest days, we have aspired to build partnerships with our grantees, offering expertise and counsel in addition to funding

In recent years, Mellon has expanded on these core principles by actively prioritizing social justice across all of our grantmaking. This strategic shift builds on our long history of advocating for and investing in expanded access to higher education, humanities, and the arts, and addressing historical inequities in these fields. Our vision for Mellon’s future includes a focus on justice for all in all that we do—rooted in the Foundation’s long-held historic belief in the impact and power of the arts and humanities. At Mellon, we make grants to actively support communities and ideas that unlock the power in the arts and humanities that helps connect us all.

Humanities in Place Grant Program

The Andrew W. Mellon Foundation actively works with our grantee partners and we are deeply immersed in the fields in which we invest. Our grants are designed to activate the spirit of learning through the creation and sharing of bold new ideas and the inspiration felt in art, expression, spaces, and scholarship. 

From Alaska to Guam and the Borderlands to the Midwest, America is a constellation of unique heritages, traditions, and stories. In communities of all sizes, people are striving to expand the ways we can understand and authentically engage with the history that is all around us. Our Humanities in Place grants fund place keepers, artists, institutions, and storytellers who shine a spotlight on historically overlooked sites, and the communities and stories that surround them. In doing so, they help broaden our shared understanding and open new paths to discover what unites us, what makes us unique, and what we can learn from one another.

Melton Foundation

The Melton Foundation is an international 501(c)(3) non-profit organization registered in the USA, and a leading proponent of Global Citizenship education and practice worldwide. Established nearly thirty years ago with the credence that collaborations across boundaries can forge sustainable solutions to the world’s most pressing challenges, today, our programs reach millions of young leaders, having crystallized into a network of over 750 life-long Melton Fellows spread across 40+ countries. Our primary operations are in Chile, China, Germany, Ghana, India, and the United States of America, with legal subsidiaries in Bangalore, India; Jena, Germany; Temuco, Chile; and Accra, Ghana. 

Through our fellowship and collaborative programs we promote and enable global citizenship as a way for individuals and organizations to work together across boundaries of place and identity to solve challenges in an interconnected world.

Melton Foundation Action Grants

The Melton Foundation offers grants year-round to support Melton Fellows in developing skills, perspective and wider networks to further their capacity as global citizens and contribute towards building an equitable, sustainable, and peaceful world.

In almost 10 years of granting, more than 100 Fellows’ initiatives have been awarded with a Melton Foundation grant to

• Build awareness and/or further awareness raising around global issues and the Sustainable Development Goals (SDGs),
• Develop individual and collective responsibility for sustained, collaborative action,
• Grow capacity to collaboratively drive and sustain social impact at the local and/or global level,
• Further the design, implementation and evaluation of collaborative actions that embody the spirit of global citizenship practice and further social impact, or
• Support coordinated social-impact efforts in a particular or across (emerging) Melton Foundation Hub regions to promote global citizenship practice (s) and the organization’s mission.

The Climate Program Office (CPO) FY2026 Earth System Science and Services Partnership (ESSSP) aims to enhance NOAA's mission through collaborative research and activities. It focuses on understanding changes in Earth's systems and their impacts on ecosystems and communities. Eligible applicants include academic institutions offering doctoral degrees in NOAA-related sciences. The total funding available is approximately $10 million, supporting initiatives that encompass research, data evaluations, and stakeholder engagement.

The R3PEATS Grassroots Rigor Projects, funded by the NIH, aim to enhance research practices through two project types: Metascience and Laboratory Capacity-Building. Metascience projects focus on creating tools and metrics to promote high-quality research, while Laboratory Capacity-Building projects help labs adopt new techniques and share data that influence research outcomes. This initiative is part of a broader effort to improve rigor, replicability, and reproducibility in scientific research.

The R3PEATS Multi-Team Triangulation initiative supports collaborative research teams to explore a central biomedical question using diverse methods and model systems. It emphasizes the importance of identifying biological variability and ensuring the robustness of findings through replication strategies. This program is part of the NIH Common Fund's Rigor, Replicability, & Reproducibility to Promote Excellence in Science, aiming to enhance the accuracy and translation of scientific discoveries.

Homeless Case Management Services Grant (HCMS)The Homeless Case Management Services (HCMS) grant provides intensive case management services to eligible families experiencing homelessness. The program is funded through the Temporary Assistance for Needy Families (TANF) block grant program and created through Wisconsin Act 59, statue §16.3085. All HCMS funds must be administered in accordance with applicable TANF requirements, rules, and regulations.

HCMS supports shelter facilities and motel voucher programs serving families experiencing homelessness. ​The HCMS program helps eligible families experiencing homelessness receive intensive case management services designed to support housing stability. Services focus on practical areas that can help families move towards stability.

Ignite WisconsinThis program is designed to increase entrepreneurial density and strengthen startup ecosystems across Wisconsin. Dense, well-connected ecosystems—where entrepreneurs, institutions and support organizations collaborate seamlessly and productively—are proven to catalyze innovation, reduce barriers to entry, and accelerate learning. These ecosystems also elevate regional and sector-based reputations, attracting talent, capital, and additional entrepreneurial activity.The program supports the development of collaborative, founder-centric ecosystems that enable scalable, high-growth startups. It prioritizes strategic investment, coordination, and capacity-building to ensure startups have access to the networks, capital, and technical assistance required to thrive. This program requires a consortium-based model to align with a broad range of partners including higher education, industry, and support organizations. The consortium-based model fosters shared vision, coordinated efforts, expanded capacity, and collective impact.

​Comprehensive Opioid, Stimulant, and Substance Use SiteBased Program (COSSUP) Wisco​nsin Deflection Initiative (WDI) Technology Implementation 2024(2026) 

This competitive grant provides funding to sites participating in the Wisconsin Deflection Initiative (WDI) to modernize deflection program processes through technology implementation. ​

Funds will support software, applications, and equipment to increase the efficiency of deflection screening, mobile case management of participants, and participant engagement and interaction. Technology implementation will improve program effectiveness, enhance data collection, and create operational efficiencies for deflection program staff.

Anticipated Funding Amount

$500,000 is available through this initiative. Individual awards are available for up to $50,000 for an initial project period. Project start dates and periods will vary depending on when applications are submitted and approved. Sites ready to begin immediately may receive funding as early as April 1, 2026, while applications will be accepted through August 31, 2026. Project budgets should reflect the specific project period based on anticipated start date.

Wisconsin Department of Health Services

The Department of Health Services (DHS) is one of the largest state agencies in Wisconsin, with an annual budget of roughly $15 billion and more than 6,700 employees. DHS is committed to protecting and promoting the health and safety of the people of Wisconsin, making sure everyone can live their best life.

Wisconsin’s Site Evaluation Program: Mini-Grants

The Wisconsin Site Evaluation Program (SEP) at the Wisconsin Department of Health Services (DHS) is seeking applications from Tribal health departments and Tribal organizations interested in addressing environmental health hazards and their impact on housing in their communities. We are offering mini-grants of up to $30,000 each to help Tribal health departments and Tribal organizations implement new, innovative, expanded, or enhanced interventions to increase tenant and homeowner environmental health literacy. The awarded Tribal health departments and Tribal organizations will build upon existing relationships they have with communities and will use or adapt strategies to meet the unique identified needs of each community.

These grant funds are intended to be used for education, community engagement, collaboration, or other forms of outreach that increase the knowledge of tenants and homeowners to identify and protect themselves from environmental hazards. Hazards addressed under this grant must relate to one or more of the following:

• Indoor air quality
• Water quality
• Soil contamination

Wisconsin Department of Natural Resources

In keeping with our mission, the Department of Natural Resources is dedicated to working with Wisconsinites while preserving and enhancing the natural resources of Wisconsin. In partnership with individuals and organizations, DNR staff manage fish, wildlife, forests, parks, air and water resources while promoting a healthy, sustainable environment and a full range of outdoor opportunities.

Urban Forestry Catastrophic Storm Grant

This grant is for tree repair, removal or replacement within urban areas following a catastrophic storm event for which the governor has declared a state of emergency under s. 323.10, Wis. Stats. A catastrophic storm means damage to urban forests caused by snow, ice, hail, wind or tornado. Catastrophic storm does not include insect infestation or disease, forest fire, drought or water saturation due to flooding.

For this grant program, no local share (also called match) is required. Grant recipients may request 50% advance payment of estimated project costs. Applications must be postmarked no later than 60 days from the date of emergency declaration. Projects must be completed within 365 days after the governor’s emergency declaration.

The Wisconsin Disaster Fund (WDF) is a state-funded reimbursement program that allows local governmental units – namely, counties, cities, townships, villages, and tribal units of government – to recoup costs incurred while responding to and recovering from disaster incidents. The state reimburses 70% of eligible costs after the local governmental unit submits a complete WDF application. The fund does not cover individuals, businesses, the agricultural sector, costs associated with snowstorms, damages covered by insurance, nor does it provide funds for mitigation activities. The fund does reimburse public disaster costs under three categories of work: Category A Debris Clearance, Category B Protective Measures, and Category C Road and Bridge Repair. The application process for WDF has two stages. The first is completed by the county/tribal emergency manager within 30 days and the second stage is completed by the applicant within EM Grants Pro (“Pro”) within 60 days of the end of the incident. The Applicant will then have 30 days to submit any additional required information or documentation.

KBF Ski Racing Safety

The KBF helps alpine ski clubs around the country purchase safety equipment like netting and padding, and also contributes to venue improvement initiatives. Funding requests are reviewed through an annual grant cycle with an application process. Over the past decade, the Kelly Brush Foundation has purchased thousands of rolls of b-netting, supported trail widening projects, and helped with the purchase of other safety equipment. 

KBF Ski Racing Safety Equipment Grants are all matching grants–meaning that any grant awarded by the Kelly Brush Foundation will need to be matched by the ski club. We expect that clubs will join us in making safety a priority by fundraising or finding room in their budget for safety.

The BJA FY 2026 Second Chance Act Community-based Reentry Program aims to support community organizations and tribal governments in providing essential mentoring and transitional services for individuals returning from correctional facilities. This initiative targets those assessed as moderate to high risk for recidivism, addressing their needs both pre-and post-release. By fostering successful reintegration into society, the program contributes to public safety and reduces recidivism rates, aligning with the mission of the U.S. Department of Justice.

The BJA FY 2026 Capital Case Litigation Initiative aims to enhance legal representation in state capital cases. By providing essential funding, this initiative supports both prosecutors and defense attorneys to ensure equitable legal processes for indigent defendants. The U.S. Department of Justice emphasizes the importance of upholding the rule of law and protecting citizens' rights. Applications are due by November 5, 2026, at 8:59 p.m. ET, marking a critical opportunity for improvement in capital case litigation.