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Best Santa Cruz County Grants for Nonprofits in Arizona

Looking for grants for 501(c)(3) nonprofit organizations working in Santa Cruz County, Arizona? Find the perfect grant for your nonprofit on Instrumentl.

9,000+

Available grants

$2.71B

Total funding

$5K

Median grant

9,000+ grants
$2.71B total
$5K median

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9,212 Results based on applied filters

NLM Grants for Scholarly Works in Biomedicine and Health (G13 Clinical Trial Not Allowed) (363939)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
US $10,000 - US $80,000
The NLM Grants for Scholarly Works in Biomedicine and Health (G13) program invites applications to support the creation of book-length manuscripts and scholarly works that are vital for U.S. health professionals and scientists. This initiative aims to foster critical reviews and analytical syntheses that enhance understanding of biomedical and public health challenges, ultimately contributing valuable resources for education, research, and clinical practice.
Health & Medicine Epidemiology & Public Health

LeverAging StraTegies to Maximize ImpLementation and Effectiveness for HIV (LAST MILE)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The LAST MILE program, initiated by the NIAID, aims to enhance the implementation and effectiveness of HIV prevention and treatment strategies through real-world effectiveness trials. By fostering collaborations and focusing on diverse populations, this initiative seeks to translate clinical findings into practical applications. The program supports research across various disciplines, aligning with the NIH's mission to improve HIV/AIDS outcomes and address associated comorbidities. This multifaceted approach promises to bridge the gap between clinical trials and community-based interventions.
Epidemiology & Public Health Infectious & Parasitic Diseases Health Care Access & Delivery +1 more

Continuation of the Exceptional Longevity Data Management and Coordinating Center (EL DMCC) (U24 Clinical Trial Not Allowed)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The National Institute on Aging (NIA) is announcing a funding opportunity to support the Exceptional Longevity Data Management and Coordinating Center (EL DMCC). This initiative aims to enhance the management of large, diverse datasets and facilitate collaborative research across NIA projects. Core functions include data integration, AI/ML infrastructure development, and maintaining the ELITE Portal for secure data access. This NOFO encourages innovative approaches to longevity research, though applications are not currently being solicited.
Biology Genetics & Genomics Emerging Technology Development

Partnerships for Advancing Development of Diagnostics for Infectious Diseases

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The National Institute of Allergy and Infectious Diseases (NIAID) aims to enhance the development of diagnostic tests for infectious diseases through strategic partnerships between academia and industry. By fostering collaborations, NIAID seeks to overcome barriers to commercialization, ensuring promising diagnostics reach the market effectively. This initiative aligns with NIH's mission to advance innovative technologies that improve treatment and prevention strategies for infectious diseases, ultimately contributing to public health advancements.
Infectious & Parasitic Diseases Emerging Technology Development Allergies & Allergic Diseases

BJA FY 2026 Prosecuting Cold Cases Using DNA

US DOJ: OJP Bureau of Justice Assistance
Federal Government
American Samoa, Guam +4 more
Up to US $750,000
The BJA FY 2026 Prosecuting Cold Cases Using DNA program aims to enhance public safety and justice by supporting prosecutors in the investigation and prosecution of violent cold case crimes with developed DNA profiles. This funding opportunity, provided by the US DOJ's OJP Bureau of Justice Assistance, facilitates crucial investigative and forensic activities to increase successful prosecutions and provide resolution for victims and their families. Full applications are due by November 5, 2026.
Crime & Justice Community / Public Safety Crime Victim Services

BJA FY 2026 Veterans Treatment Court Program

Bureau of Justice Assistance
Federal Government
American Samoa, Guam +4 more
Up to US $2,500,000
The BJA FY 2026 Veterans Treatment Court Program aims to enhance operations for veterans in the criminal justice system, focusing on reducing substance use, including opioids and alcohol. It integrates treatment for substance use and mental health disorders within a judicial framework, targeting high-risk veterans. This initiative not only addresses public safety concerns but also aims to provide necessary support and resources for veterans dealing with issues like PTSD and traumatic brain injury, fostering rehabilitation and recovery.
Military & Veterans Services Mental Health & Psychiatric Diseases Crime & Justice +1 more

OJJDP FY 2026 Juvenile Drug Treatment Court Program

US Department of Justice: Bureau of Justice Assistance
Federal Government
American Samoa, Guam +4 more
Up to US $1,000,000
The OJJDP FY 2026 Juvenile Drug Treatment Court Program aims to enhance juvenile drug treatment courts (JDTCs) across the U.S. by supporting states, local courts, and Tribal governments. This initiative focuses on improving outcomes for youth dealing with substance use disorders or co-occurring mental health issues. The program underscores the commitment of the Office of Justice Programs to strengthen community safety and provide vital resources for effective intervention and support.
Mental Health & Psychiatric Diseases Youth Services Crime & Justice +1 more

OJJDP FY 2026 Missing and Exploited Children Training and Technical Assistance

US DOJ: Office of Juvenile Justice & Delinquency Prevention (OJJDP)
Federal Government
American Samoa, Guam +4 more
Up to US $1,200,000
The OJJDP FY 2026 Missing and Exploited Children Training and Technical Assistance program aims to enhance the ability of state, Tribal, and local agencies to effectively address cases of missing and exploited children. This initiative will support multidisciplinary teams, including law enforcement and child protection personnel, to improve investigations and prosecutions. By providing essential resources and training, the program seeks to strengthen responses to protect vulnerable children and combat related public safety issues.
Youth Services Crime & Justice Crime Victim Services

OJJDP FY 2026 Community and Schools Youth Drug Prevention Program

US Department of Justice: Bureau of Justice Assistance
Federal Government
American Samoa, Guam +4 more
Up to US $750,000
The OJJDP FY 2026 Community and Schools Youth Drug Prevention Program aims to combat youth substance use through comprehensive prevention strategies. This initiative invites applications from states, local governments, and nonprofit organizations to develop programs that educate and support youth in schools and community settings. By fostering collaboration with law enforcement and community coalitions, the program seeks to build capacity and implement effective interventions to protect the well-being of American youth.
Youth Services Addiction & Substance Use Disorders Preventative Healthcare

Fiscal Year (FY) 2027 Department of War (DoW) Multidisciplinary Research Program of the University Research Initiative (MURI)

US DOD: Dept. of the Air Force, Materiel Command
Federal Government
American Samoa, Guam +4 more
Up to US $15,000,000
The FY 2027 Department of War Multidisciplinary Research Program of the University Research Initiative (MURI) aims to fund U.S. academic teams conducting innovative research to tackle complex challenges for the Department of War. Established in 1985, MURI promotes collaboration among diverse scientific disciplines, enhancing the defense workforce and addressing critical areas of interest through multidisciplinary research efforts at U.S. universities.
Engineering Education - Higher Education Science +1 more

BJA FY 2026 National Center for Veterans Justice

Bureau of Justice Assistance
Federal Government
American Samoa, Guam +4 more
Up to US $4,000,000
The BJA FY 2026 National Center for Veterans Justice aims to enhance support for veterans in the criminal justice system. By providing specialized training and resources to law enforcement and service providers, the center will address critical gaps in veteran identification and coordination among agencies. This initiative seeks to improve outcomes for veterans experiencing issues like PTSD and military sexual trauma, ultimately strengthening public safety and ensuring effective responses to their unique needs.
Military & Veterans Services Mental Health & Psychiatric Diseases Crime & Justice

BJA FY 2026 Paul Coverdell Forensic Science Improvement- Competitive Grants Program

US Department of Justice: National Institute of Justice (NIJ)
Federal Government
American Samoa, Guam +4 more
Up to US $500,000
The BJA FY 2026 Paul Coverdell Forensic Science Improvement- Competitive Grants Program aims to enhance forensic science and medical examiner/coroner services across the U.S. This funding opportunity supports state and local government laboratories in improving their capabilities to ensure justice and public safety. Applications are due by November 5, 2026, at 8:59 p.m. ET, promoting advancements in forensic practices to better serve law enforcement and communities.
Crime & Justice Community / Public Safety

BJA FY26 Paul Coverdell Forensic Science Improvement - Formula Grants Program

US Department of Justice: National Institute of Justice (NIJ)
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The BJA FY26 Paul Coverdell Forensic Science Improvement - Formula Grants Program supports state agencies in enhancing forensic science capabilities. The program aims to improve public safety by funding initiatives that strengthen forensic science and support law enforcement efforts. Eligible applicants can submit their full applications through JustGrants by November 6, 2026. This funding is crucial for addressing ongoing challenges in the justice system, including violent crime and public safety concerns.
Crime & Justice Community / Public Safety

OJJDP FY 2026 Multistate Mentoring Programs

US DOJ: Office of Juvenile Justice & Delinquency Prevention (OJJDP)
Federal Government
American Samoa, Guam +4 more
US $1,000,000 - US $4,000,000
The OJJDP FY 2026 Multistate Mentoring Programs aims to provide crucial mentoring services to at-risk youth, helping them avoid delinquency and victimization. This funding opportunity emphasizes the importance of one-on-one, group, and peer mentoring approaches. The program aligns with the U.S. Department of Justice's commitment to public safety and juvenile justice reform, addressing the needs of vulnerable populations and fostering positive youth development.
Youth Services Crime & Justice Youth Development & Leadership +1 more

OJJDP FY 2026 Strengthening Internet Crimes Against Children (ICAC) Technological Investigative Capacity

US DOJ: Office of Juvenile Justice & Delinquency Prevention (OJJDP)
Federal Government
American Samoa, Guam +4 more
Up to US $675,000
The OJJDP FY 2026 Strengthening Internet Crimes Against Children (ICAC) program aims to enhance the technological investigative capacity of ICAC task forces nationwide. Through this funding opportunity, the program will support the development and refinement of investigative tools and methods to combat child sexual abuse material, exploitation, and trafficking. The deadline for application submission is November 5, 2026, at 8:59 p.m. ET, emphasizing the urgency of addressing these critical issues.
Crime & Justice Human Trafficking Crime Victim Services +1 more

Fiscal Year (FY) 2027 Department of War (DoW) Multidisciplinary Research Program of the University Research Initiative (MURI) (363905)

US DOD: U.S. Army Materiel Command
Federal Government
American Samoa, Guam +4 more
Up to US $7,500,000
The FY 2027 Department of War Multidisciplinary Research Program (MURI) funds U.S. academic teams engaged in innovative basic research addressing future defense challenges. Established in 1985, MURI emphasizes collaboration across multiple scientific disciplines to tackle complex, DoW-relevant issues. By fostering partnerships among faculty, postdoctoral researchers, and students, the program aims to advance the U.S. defense industrial base and nurture a skilled scientific workforce, contributing to significant breakthroughs in military technology and economic growth.
Engineering Science Workforce Preparation & Job Readiness +1 more

OJJDP FY 2026 Victims of Child Abuse Act Training and Technical Assistance for Child Abuse Professionals

US DOJ: Office of Juvenile Justice & Delinquency Prevention (OJJDP)
Federal Government
American Samoa, Guam +4 more
Up to US $2,850,000
The OJJDP FY 2026 Victims of Child Abuse Act Training and Technical Assistance program aims to enhance the skills of child abuse professionals. This initiative will promote coordinated investigations and improve intervention strategies for child abuse victims. By providing essential training on effective interviewing, investigative techniques, and interagency collaboration, the program seeks to elevate the quality of care and support available to affected children and families. Applications are due by November 5, 2026.
Youth Services Crime & Justice Crime Victim Services

BJA FY 2026 Rural Violent Crime Reduction Initiative

Bureau of Justice Assistance
Federal Government
American Samoa, Guam +4 more
Up to US $250,000
The BJA FY 2026 Rural Violent Crime Reduction Initiative aims to empower local law enforcement in rural areas to combat violent crime effectively. This funding opportunity provides resources for personnel, technology, and data analytics to enhance crime prevention strategies. Eligible applicants can utilize updated equipment and training to address specific violent crime challenges, ensuring safer communities through innovative approaches and strategic resource allocation. Applications are due by November 6, 2026.
Crime & Justice Rural Development Community / Public Safety +1 more

Fiscal Year (FY) 2027 Department of War Multidisciplinary Research Program of the University Research Initiative (MURI)

US DOD: Dept. of the Navy, Office of the Chief of Naval Research
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The Fiscal Year 2027 Department of War Multidisciplinary Research Program aims to fund innovative research teams from U.S. universities. Established in 1985, this initiative addresses complex challenges faced by the Department of War, fostering collaboration across various scientific disciplines. By integrating world-class faculty and graduate students, the program seeks to cultivate a skilled workforce poised to enhance the U.S. defense capabilities and contribute to the advancement of the defense industrial base.
Engineering Education - Higher Education Science +1 more

BJA FY 2026 Students, Teachers, and Officers Preventing (STOP) School Violence Program

US DOJ: Office of Justice Programs
Federal Government
American Samoa, Guam +4 more
Up to US $2,000,000
The BJA FY 2026 Students, Teachers, and Officers Preventing (STOP) School Violence Program aims to enhance school safety by funding initiatives that train staff and students, develop threat assessment teams, and implement technology solutions like anonymous reporting systems. This program supports effective strategies to identify and mitigate risks of school violence, ensuring students have the tools necessary to foster a secure learning environment while adhering to the guidelines set forth by the STOP School Violence Act.
Community / Public Safety Violence Prevention School Safety +1 more

FY23- Bellows Falls Intermodal Center Rehabilitation

DOT - Federal Railroad Administration
Federal Government
American Samoa, Guam +4 more
Up to US $1,800,000
The FY23 Bellows Falls Intermodal Center Rehabilitation grant aims to restore the passenger station to a state of good repair, enhancing its appeal and functionality as an intermodal transportation hub. This initiative will not only improve transit services but also play a pivotal role in the economic revitalization of the surrounding community. The grant will be administered by the Vermont Agency of Transportation, ensuring effective utilization of funds for community development.
Economic Services & Development Public Transportation & Mass Transit Systems

State Biomonitoring Cooperative Agreement

Dept. of Health & Human Services: Centers for Disease Control & Prevention
Federal Government
American Samoa, Guam +4 more
US $750,000 - US $900,000
The State Biomonitoring Cooperative Agreement aims to enhance public health laboratories' ability to conduct biomonitoring and assess human exposure to environmental chemicals. This funding opportunity emphasizes community investigations, state-level studies, and emerging chemicals not covered in the National Exposure Report. By improving laboratory capacity and fostering collaboration, the initiative seeks to identify harmful exposures and evaluate intervention effectiveness over a three-year period.
Epidemiology & Public Health Environmental Contamination & Pollution Environmental Health

Multiple Sclerosis (MS) Grant

Patient Advocate Foundation
Private
U.S. Territories, United States
US $3,000 - US $8,000

About Patient Advocate Foundation

Patient Advocate Foundation is the nation’s most comprehensive nonprofit dedicated to helping patients navigate, access, and afford the care they need—while improving the healthcare system for all.

Who we are and our impact

Patient Advocate Foundation provides financial assistance to help patients afford treatment and cost of living needs, personalized case management to navigate complex healthcare and social needs challenges, and a wide array of resources to empower people to take charge of their health. Since our founding in 1996—and joining forces with the PAN Foundation in 2026—we have helped 3.8 million patients navigate and access care, granted over $7 billion in financial assistance, served 350,000 people through personalized case management and elevated the patient’s voice to drive improvements in the healthcare system.

Multiple sclerosis (MS)

Help with healthcare costs for Multiple sclerosis (MS)

This TotalAssist fund helps you pay for out-of-pocket healthcare costs, including medication copays, coinsurance, and deductibles, health insurance premiums, and other expenses.

About the disease

Multiple sclerosis (MS) is a potentially disabling disease of the central nervous system in which the insulating covers of the nerve cells in the brain and spinal cord are damaged. MS is a chronic disease that affects the nervous system.

Health Care Access & Delivery Chronic Illnesses Health Disparities & Social Determinants of Health +1 more

Multiple Sclerosis (MS) Health Equity Grant

Patient Advocate Foundation
Private
U.S. Territories, United States
US $3,000 - US $8,000

About Patient Advocate Foundation

Patient Advocate Foundation is the nation’s most comprehensive nonprofit dedicated to helping patients navigate, access, and afford the care they need—while improving the healthcare system for all.

Who we are and our impact

Patient Advocate Foundation provides financial assistance to help patients afford treatment and cost of living needs, personalized case management to navigate complex healthcare and social needs challenges, and a wide array of resources to empower people to take charge of their health. Since our founding in 1996—and joining forces with the PAN Foundation in 2026—we have helped 3.8 million patients navigate and access care, granted over $7 billion in financial assistance, served 350,000 people through personalized case management and elevated the patient’s voice to drive improvements in the healthcare system.

Multiple sclerosis (MS) health equity

Help with healthcare costs for multiple sclerosis (health equity)

This TotalAssist fund helps you pay for out-of-pocket healthcare costs, including medication copays, coinsurance, and deductibles, health insurance premiums, and other expenses.

Health Equity Funds offer help to eligible patients living in areas identified as having increased social and financial needs, as well as higher rates of chronic conditions. Eligibility is determined in part by home address zip code. 

About the disease

Multiple sclerosis (MS) is a potentially disabling disease of the central nervous system in which the insulating covers of the nerve cells in the brain and spinal cord are damaged. MS is a chronic disease that affects the nervous system.

Health Care Access & Delivery Multiple Sclerosis Chronic Illnesses +1 more

Paroxysmal Nocturnal Hemoglobinuria (PNH) Grant

Patient Advocate Foundation
Private
U.S. Territories, United States
US $6,900 - US $9,500

About Patient Advocate Foundation

Patient Advocate Foundation is the nation’s most comprehensive nonprofit dedicated to helping patients navigate, access, and afford the care they need—while improving the healthcare system for all.

Who we are and our impact

Patient Advocate Foundation provides financial assistance to help patients afford treatment and cost of living needs, personalized case management to navigate complex healthcare and social needs challenges, and a wide array of resources to empower people to take charge of their health. Since our founding in 1996—and joining forces with the PAN Foundation in 2026—we have helped 3.8 million patients navigate and access care, granted over $7 billion in financial assistance, served 350,000 people through personalized case management and elevated the patient’s voice to drive improvements in the healthcare system.

Paroxysmal Nocturnal Hemoglobinuria (PNH)

Help with healthcare costs for Paroxysmal Nocturnal Hemoglobinuria (PNH)

This TotalAssist fund helps you pay for out-of-pocket healthcare costs, including medication copays, coinsurance, and deductibles, health insurance premiums, and other expenses.

About the disease

Paroxysmal Nocturnal Hemoglobinuria (PNH), also known as Marchiafava– Micheli syndrome, is a rare disease that is characterized by impaired bone marrow function and destruction of red blood cells. PNH is a rare disease that affects the circulatory system.

Rare Diseases Health Care Access & Delivery Health Disparities & Social Determinants of Health +1 more

Periodic Paralysis Grant

Patient Advocate Foundation
Private
U.S. Territories, United States
US $750 - US $1,500
The Periodic Paralysis Grant, offered by the Patient Advocate Foundation, assists individuals diagnosed with periodic paralysis in managing out-of-pocket healthcare costs. Eligible applicants must be in treatment or planning to begin treatment for this rare muscle disease. The fund covers various expenses, including medication copays and insurance premiums, ensuring that patients can afford essential care. With a mission to empower and support patients, this grant plays a crucial role in navigating healthcare challenges.
Rare Diseases Health Care Access & Delivery Health Disparities & Social Determinants of Health +1 more

Philadelphia Chromosome Negative Myeloproliferative Neoplasms (MPN) Grant

Patient Advocate Foundation
Private
U.S. Territories, United States
US $4,000 - US $9,500
The Philadelphia Chromosome Negative Myeloproliferative Neoplasms (MPN) Grant, offered by the Patient Advocate Foundation, provides crucial financial assistance to patients facing this cancer type. It covers out-of-pocket healthcare costs, including medication copays and insurance premiums, ensuring those affected can access necessary treatments. With a focus on personalized case management, the foundation has supported millions in navigating their healthcare needs, emphasizing the importance of timely and affordable care for patients diagnosed with MPN.
Health Care Access & Delivery Health Disparities & Social Determinants of Health Cancer / Oncology +2 more

Santa Cruz County Grants for Nonprofits Highlights

Looking for Santa Cruz County grants for nonprofits?


Read more about each grant below or start your 14-day free trial to see all Santa Cruz County grants recommended for your specific programs in Arizona.

Last updated: October 5, 2026. Next update: November 1, 2026.

Grant Insights : Grant Funding Trends in Arizona

Average Grant Size

What's the typical amount funded for Arizona?

Grants are most commonly $116,794.

$116,794

Total Number of Grants

What's the total number of grants in Santa Cruz County Grants for Nonprofits year over year?

In 2024, funders in Arizona awarded a total of 32,255 grants.

2022 28,693

2023 30,847

2024 32,255

Top Grant Focus Areas

Among all the Santa Cruz County Grants for Nonprofits given out in Arizona, the most popular focus areas that receive funding are Education, Human Services, and Philanthropy, Voluntarism & Grantmaking Foundations.

1. Education

2. Human Services

3. Philanthropy, Voluntarism & Grantmaking Foundations

Funding Over Time

How is funding for Santa Cruz County Grants for Nonprofits changing over time?

Funding has increased by 18.51%.

2022 $3,028,974,870

2023 $3,163,785,616
4.45%

2024 $3,749,331,047
18.51%

Arizona Counties That Receive the Most Funding

How does grant funding vary by county?

Maricopa County, Pima County, and Coconino County receive the most funding.

County Total Grant Funding in 2024
Maricopa County $2,601,929,541
Pima County $787,444,349
Coconino County $236,303,583
Yavapai County $81,123,787
Gila County $64,666,331