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Best Quality of Life Grants in South Carolina

Find the perfect Quality of Life Grants in South Carolina on Instrumentl. 9,000+ Quality of Life Grants in South Carolina in the United States.

9,000+

Available grants

$2.62B

Total funding

$5K

Median grant

9,000+ grants
$2.62B total
$5K median

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Store-Based Giving Program Grant

Ross Stores Foundation
Private
United States
US $300 - US $500
The Store-Based Giving Program by Ross Stores Foundation supports socioeconomically disadvantaged youth by providing gift cards for school or professional clothing. Organizations must be federal tax-exempt and serve at least 60% low-income youth. Eligible programs include academic achievement and life skills initiatives. Award amounts typically range from $300 to $500, depending on budget and mission alignment. Applications are not accepted from organizations that have received donations within the past 12 months.
Youth Services Financial Literacy Career / College Preparation +2 more

HIV/AIDS Clinical Trials Network Leadership and Operations Centers

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The National Institute of Allergy and Infectious Diseases (NIAID) is calling for applications for four Leadership and Operations Centers (LOCs) as part of its HIV/AIDS Clinical Trials Network initiative. These LOCs will guide research on HIV therapeutics, prevention, and treatment strategies across diverse populations. The initiative aims to enhance evidence-based practices and improve health outcomes for individuals affected by HIV, ultimately contributing to the goal of ending the HIV epidemic.
HIV / AIDS

ASSP Foundation Academic Scholarships

American Society of Safety Professionals (ASSP) Foundation
Association/Society
United States
Unspecified amount
The ASSP Foundation Academic Scholarships provide vital financial support to students in environmental health and safety programs. With over $6 million awarded since 1990, the foundation aims to enhance career prospects through education and leadership development. In the 2024-2025 academic year, $215,000 was allocated to 117 recipients, fostering a sustainable talent pipeline in EHS. This initiative not only promotes the profession but also ensures a safer future for workers by encouraging new talent to enter the field.
Occupational Health & Safety Environmental Health Workforce Preparation & Job Readiness +1 more

Survivorship and Supportive Care Research Grant

St Baldricks Foundation Inc
Private
United States
Up to US $50,000

St. Baldrick's Foundation

The St. Baldrick's Foundation is a volunteer and donor powered charity committed to supporting the most promising research to find cures for childhood cancers and give survivors long and healthy lives. It started with a friendly dare: would you shave your head to raise money for kids’ cancer research? What happened next would change the world. This bold act of baldness has gained major momentum, since its start in 2000. Today, we have more than 1,000 head-shaving events taking place around the world at pubs, restaurants, schools, churches, parks, firehouses, military bases – you name it. It is our constituents’ way of changing the world, in a meaningful way. Volunteers also raise funds through athletic challenges, livestream fundraisers and many other activities.

Since the Foundation's first grants as an independent charity in 2005, St. Baldrick's has invested more than $380 million in childhood cancer research grants worldwide.

About Allied World

Allied World Assurance Company Holdings, Ltd, through its subsidiaries, is a global provider of insurance and reinsurance solutions. The company operates under the brand Allied World and has supported clients, cedents and trading partners with thoughtful service and meaningful coverages since 2001. Since the inception of St. Baldrick’s, Allied World has supported childhood cancer research through the Foundation, and it is the largest of many reinsurance company sponsors, making this life-saving mission a top priority.

Survivorship and Supportive Care Research Grant

These grants are for specific one-year research projects which are hypothesis-driven and focus on areas related to survivorship and supportive care of children and adolescents with cancer. Examples include but are not limited to: studies related to the burden of morbidity, cause-specific mortality, understanding the pathogenesis of treatment-related complications, patient-reported outcomes or quality of life, health communication, health promotion, and psychosocial support across the trajectory from diagnosis to survivorship or end-of-life care.

Projects must have direct applicability and relevance to pediatric cancer. They may be in any discipline of basic, clinical, translational, or epidemiological research.

Cancer / Oncology Pediatric Cancers Patient Care & Services

Fiscal Year (FY) 2027 Service Area Competition (SAC) (363777)

US HHS: Health Resources & Services Administration (HRSA)
Federal Government
American Samoa, Guam +7 more
US $650,000 - US $1,500,231
The FY 2027 Service Area Competition (SAC) funding aims to enhance health services in underserved communities across the U.S. by providing grants for comprehensive preventive and primary care. This initiative allows for a competitive selection of service areas, ensuring that health centers can effectively deliver high-quality healthcare. Additional service areas may be announced throughout the year to accommodate changes in service availability, supporting continuous care for those in need.
Epidemiology & Public Health Health Care Access & Delivery Preventative Healthcare +2 more

Accelerating Research and Development of Next Generation Malaria Vaccines Against Malaria – A Model for Mosquito-Borne Diseases

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The NIAID is focused on advancing the research and development of next-generation malaria vaccines, aiming to leverage innovative vaccine design techniques. This initiative not only aims to enhance malaria prevention but also serves as a model for combating other mosquito-borne diseases. By utilizing cutting-edge methods such as structure-based immunogen design and combination vaccines, the program seeks to significantly reduce both parasite infection rates and the overall disease burden associated with malaria.
Malaria Tropical Diseases

Corporate Giving - Charitable Contributions

McCormick & Company, Inc
Corporate
United States
Unspecified amount
McCormick & Company, Inc. actively supports charitable contributions through its Charitable Donations Committee (CDC), which prioritizes donations to non-profit organizations that enhance education, health, environment, and culture. The CDC focuses on organizations that benefit communities where McCormick employees live and work, ensuring a positive impact. Eligible groups must be tax-exempt and demonstrate a commitment to non-discrimination. However, donations are not made to individuals, political organizations, or entities that conflict with corporate values.
Environment Art & Culture Health & Medicine +4 more

Never Let Go Fund

Emporia Community Foundation
Private
United States
Up to US $2,000

About the Emporia Community Foundation

Our Mission

To connect caring people with causes that build stronger communities within the Emporia area which includes Chase, Coffey, Greenwood, Lyon, Morris, Osage and Wabaunsee counties.

Never Let Go Fund

The purpose of the Never Let Go Fund is to provide funds to qualified individuals to cover expenses related to the treatment of childhood cancer. Grant requests will be considered for children under the age of 18.

Health Care Access & Delivery Cancer / Oncology Children’s Health & Pediatrics +1 more

United States Adult Cystic Fibrosis Association (USACFA): Higher Education Scholarship

United States Adult Cystic Fibrosis Association (USACFA)
Association/Society
United States
Up to US $2,500
The United States Adult Cystic Fibrosis Association (USACFA) offers a Higher Education Scholarship, honoring Lauren Melissa Kelly. This scholarship awards up to $2500 to two adults with cystic fibrosis pursuing various educational paths. Applicants must show proof of enrollment for the relevant academic year and can cover education-related costs, including tuition and materials. This initiative not only supports education but also commemorates Lauren's legacy, inspiring others to pursue their dreams despite challenges.
Cystic Fibrosis Academic Scholarship Programs Education - Higher Education +1 more

21st Century Museum Professionals Program (2027)

Institute of Museum and Library Services
Federal Government
American Samoa, Guam +7 more
US $100,000 - US $500,000
The 21st Century Museum Professionals (21MP) Program, funded by the Institute of Museum and Library Services, aims to enhance career pathways and professional networks in the museum sector. This initiative focuses on developing current museum staff, recruiting new professionals, and fostering partnerships that promote effective workforce training. By emphasizing peer learning and alternative career pathways, the program seeks to create a robust and diverse museum workforce across the nation.
Education - Higher Education Workforce Preparation & Job Readiness Museums & Cultural Institutions +1 more

HEAL Initiative: Integrative Management of Chronic Pain and Opioid Use Disorder (OUD) for Whole Recovery: Health Systems

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The HEAL Initiative aims to address the complex interplay between chronic pain and opioid use disorder (OUD), affecting 40-60% of OUD patients. Through the IMPOWR initiative, this funding opportunity seeks to develop integrated care strategies that enhance treatment delivery at health systems levels. By identifying effective interventions and collaborative care models, the initiative strives to improve patient outcomes in managing both chronic pain and OUD, while emphasizing the roles of various healthcare professionals in this integrated approach.
Epidemiology & Public Health Addiction & Substance Use Disorders Health Care Access & Delivery +3 more

Native Performing Arts Live Production Grant (LPG)

First Peoples Fund
Private
United States
US $30,000
The Native Performing Arts Live Production Grant (LPG) supports Native artists and organizations in staging live performances, fostering cultural expression. With a $30,000 grant for one year, this initiative prioritizes projects that actively engage Native performers, enhancing their artistic skills and community connections. By addressing the unique needs of Native creators, the program aims to empower them with resources, mentorship, and equitable opportunities in the performing arts landscape.
Music Theater Dance +1 more

Wild Animal Initiative: Seed Grants

Wild Animal Initiative
Private
Afghanistan, Albania +189 more
Up to US $30,000
The Wild Animal Initiative offers Seed Grants to support innovative projects in wild animal welfare research. These grants aim to facilitate early-career researchers and established scientists in testing new techniques and approaches that incorporate welfare assessments into ecological studies. The program emphasizes cost-effective solutions, focusing on improving the welfare of wild animals. Successful proposals will explore diverse themes such as wild fish welfare and near-term welfare interventions to address urgent animal welfare challenges.
Wildlife Health Ichthyology (Fish)

Geoff Richter Performing Arts Award

Foundation For Jewish Philanthropies
Private
United States
US $2,000

Our Mission

Empower donors to fulfill their passions and dreams by establishing charitable vehicles designed to create a positive and enduring impact on Jewish Buffalo, Western New York and the World.

Geoff Richter Performing Arts Award

The Geoff Richter Performing Arts Award Committee announces the availability of an Award up to $2,000! The GRPAA was founded in memory of Geoff Richter, Western New York Musician and Educator of the Arts.

About Geoff Richter

A native of Eden, New York, Geoff received his Bachelor of Music degree with a Performer’s Certificate in trumpet and a Master’s with a Performers Fellowship, from the Eastman School of Music.

Geoff played trumpet professionally with the Rochester, San Antonio, and Buffalo Philharmonic Orchestras and Niagara Falls, Binghamton, Chautauqua, Orchard Park, Clarence, Cheektowaga, and Amherst Symphony Orchestras. He co-founded the Buffalo Brass Quintet, the Buffalo Niagara Concert Band, and The Frankfurters, an internationally known Bavarian show band. He also acted as the summer/pops conductor of the Erie County Wind Ensemble and the Amherst Symphony Orchestra.

After retiring from a long career at Williamsville North High School, Geoff started working part time as director of the orchestra for musicals at St. Joseph Collegiate Institute. He also worked with the Mount Saint Mary Academy band and recruited and directed the orchestra for the annual school musical.

Performing Arts Education - Higher Education Music +2 more

The Anne and Tony Hillerman Scholarship

Albuquerque Community Foundation
Private
New Mexico, United States
Unspecified amount
The Anne and Tony Hillerman Scholarship, part of the New Mexico Press Women Scholarship Fund, supports New Mexico students pursuing undergraduate or graduate degrees in journalism or communications. Established in 2023, the fund promotes ethical journalism and offers networking opportunities through the NMPW Annual Conference. Eligible applicants must be enrolled in a relevant program, provide a portfolio of work, and submit a personal essay detailing their interests and career goals. This scholarship fosters the next generation of communicators and advocates for First Amendment rights.
Education - Higher Education Vocational & Trade Education Career / College Preparation +3 more

Kiwanis Club of Albuquerque Scholarship Fund

Albuquerque Community Foundation
Private
United States
Up to US $1,000
The Kiwanis Club of Albuquerque Scholarship Fund, established in 1948, supports graduating seniors from Albuquerque metro area high schools who demonstrate strong academic performance and community service. Annually, one to four scholarships of up to $1,000 are awarded to students pursuing careers in child development and teaching. The fund emphasizes the importance of community involvement and academic excellence, encouraging students to share their career goals and financial needs through an essay as part of their application.
Education - Higher Education Vocational & Trade Education Career / College Preparation +3 more

Community Care Corps RFP

Community Care Corps
Federal Government
United States
US $30,000 - US $200,000

Request for Proposals

Community Care Corps encourages organizations across the country to apply for 18-month grants ($30,000–$200,000) to develop and scale innovative volunteer programs that provide nonmedical assistance to older adults, adults age 18 and older with disabilities and family caregivers.

Projects funded through this initiative will increase the number of community-based volunteer programs available to provide nonmedical assistance while decreasing the number of older adults, adults with disabilities, and family caregivers who need assistance in maintaining independence in the community but are unable to obtain help. In doing so, the initiative will strengthen community-based supports that help people maintain independence, reduce unmet needs, and improve overall well-being.

Senior Services Caregiver Support / Respite Care Disability Care & Services +1 more

Promoting a Basic Understanding of Chemical Threats to Skin (R01 Clinical Trial Not Allowed)

National Institutes of Health
Federal Government
American Samoa, Guam +4 more
US $2,500,000
The National Institutes of Health is launching a funding opportunity to explore the mechanisms of skin injuries caused by toxic chemicals. This initiative aims to understand the common pathways of injury from various harmful substances, facilitating the discovery of therapeutic targets. Researchers are encouraged to collaborate and apply their expertise in cutaneous wound healing. The goal is to develop broad-spectrum medical countermeasures for mass casualty events involving toxic exposures, enhancing public health safety.
Cell Biology Environmental Chemistry & Toxicology Wounds & Injuries +1 more

Trail Accelerator Grants- Spring Cycle Planning and Design

International Mountain Bicycling Association
Private
United States
US $10,000 - US $30,000
The Trail Accelerator Grants aim to enhance mountain bike trail communities by providing essential planning and design services. With funding between $10,000 to $30,000, these grants support local organizations in creating sustainable trail systems. The initiative encourages projects that increase access and promote community engagement, particularly focusing on diversity and inclusion. Applicants must demonstrate the capacity to match funds, ensuring collaborative efforts to improve trail networks and experiences for all riders.
Trail Creation & Maintenance Biking Pedestrian & Bike-Friendly Infrastructure

Early Stage Investigator HIV/AIDS Research Using Nonhuman Primate (NHP) Models (R21 Clinical Trial Not Allowed) (348960)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Up to US $400,000
This funding opportunity aims to support Early Stage Investigators (ESIs) in conducting preclinical HIV/AIDS research using Nonhuman Primate (NHP) models. Eligible applicants must have at least two years of postdoctoral experience and be within ten years of their terminal degree. The initiative aligns with the NIH Strategic Plan for HIV and HIV-Related Research, targeting the reduction of HIV incidence, development of therapies, and advancement in research areas related to HIV.
HIV / AIDS

Capacity Building for National Immunization Programs in the Eastern Mediterranean Region (363749)

Dept. of Health & Human Services: Centers for Disease Control & Prevention
Federal Government
American Samoa, Guam +4 more
Unspecified amount
This grant aims to enhance national immunization programs in the Eastern Mediterranean Region by focusing on capacity building, disease control, and outbreak response. It seeks to eliminate vaccine-preventable diseases, reduce morbidity and mortality, and improve access for under-immunized populations. The initiative will promote sustainability through evidence-based decision-making and program evaluation, aligning with CDC goals to address public health threats and improve overall immunization impact in the region.
Epidemiology & Public Health Infectious & Parasitic Diseases Health Care Access & Delivery +2 more

New Mexico Veterans Memorial Scholarship

Albuquerque Community Foundation
Private
United States
Unspecified amount
The New Mexico Veterans Memorial Scholarship, established in 2024, supports graduating high school seniors in New Mexico who embody the Medal of Honor Core Values: Courage, Sacrifice, Integrity, Commitment, Patriotism, and Citizenship. This scholarship encourages students to explore and reflect on these values through a personal essay and community service. Preference is given to students from Albuquerque High Schools, fostering a commitment to excellence and civic duty among the youth.
Education - Higher Education Vocational & Trade Education Career / College Preparation +3 more

Grief Reach: Changemaker Supported Community Expansion Cycle- up to $160,000

National Alliance for Children's Grief (NACG)
Private
United States
Up to US $160,000
The Grief Reach grant program, supported by the New York Life Foundation and the National Alliance for Children's Grief, invites innovative community expansion proposals to better serve grieving children. Eligible organizations can apply for funding up to $160,000 to enhance their programs, focusing on unique community needs. By collaborating with the Judi's House/JAG Institute, participants will receive essential training and resources for impactful program evaluation, fostering a supportive environment for children and families facing grief.
Mental Health & Psychiatric Diseases Youth Services Family Services +1 more

Harry Kramer Memorial Fund Grant

Harry Kramer Memorial Fund
Private
Israel, United States
US $10,000 - US $25,000
The Harry Kramer Memorial Fund Grant supports U.S. charitable organizations that assist individuals and institutions in Israel, focusing on welfare, healthcare for the sick and aged, and education in South Florida. Founded by Harry A. Kramer, a successful entrepreneur and veteran, the fund reflects his deep commitment to charitable causes. Organizations must qualify under Section 501(c)(3) and meet specific eligibility criteria to apply for funding, ensuring that aid reaches those in need.
Jewish Culture Senior Services Religion & Spirituality +4 more

Grief Reach: Changemaker Supported Community Expansion Cycle - up to $110,000

National Alliance for Children's Grief (NACG)
Private
United States
Up to US $110,000
The Grief Reach: Changemaker Supported Community Expansion Cycle offers up to $110,000 to enhance community programs for grieving children. Organizations are encouraged to innovate and expand their services to better meet community needs. The initiative, in partnership with the Judi’s House/JAG Institute, emphasizes training and resources for effective program evaluation over a three-year period, culminating in impactful community expansion projects.
Children’s Mental Health Mental Health & Psychiatric Diseases Family Services +1 more

Burger Family Foundation: Pens Pearls Grant Program

Burger Family Foundation
Private
United States
Unspecified amount

Burger Family Foundatio

Our Mission

Inspired by our daughter Penelope and the powerful symbolism of the extra 21st chromosome, our foundation is dedicated to creating opportunities for individuals with Down syndrome and their families. Through direct financial assistance, therapy, community, and the healing power of ranch life, we’re building spaces that foster hope, purpose, and belonging.

Pens Pearls

Named after Penelope, Pens Pearls is the financial support arm of our foundation, providing direct assistance to families navigating the unique joys and challenges of raising a child with a disability. From therapy grants to life-changing opportunities, we’re here to lighten the load and ensure every child has the resources they need to thrive.

Through Pens Pearls, eligible families can apply for funding to help cover essential needs, services, or opportunities that make a meaningful impact in their lives. The Burger Family Foundation is a 501(c)(3) organization, and this program is one of the ways we work to create lasting change—one story at a time.

Qualifications for Pens Pearls Grant Program, are deemed by the strict bylaws of the Burger Family Foundation. Funds are paid directly to provider. 

Down Syndrome Children With Disabilities Intellectual / Developmental Disabilities

NIAMS Clinical Trial Implementation Cooperative Agreement

National Institutes of Health
Federal Government
American Samoa, Guam +4 more
More than US $250,000
The National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) is inviting applications for the Clinical Trial Cooperative Agreement Program. This funding opportunity supports investigator-initiated, interventional clinical trials at various phases. Initial funding will facilitate the preparation needed to start trials, with successful milestones leading to further support. NIAMS emphasizes hypothesis-driven trials that promise significant clinical impact within its research mission.
Musculoskeletal Diseases Arthritis Skin Diseases & Dermatology

Quality of Life Grants in South Carolina Highlights

Looking for quality of life grants in South Carolina?


Read more about each grant below or start your 14-day free trial to see all quality of life grants in South Carolina recommended for your specific programs.

Last updated: October 5, 2026. Next update: November 1, 2026.

Grant Insights : Quality of Life Grants in South Carolina

Grant Availability

How common are grants in this category?

Common — grants in this category appear regularly across funding sources.

200+ Quality of Life Grants in South Carolina grants for nonprofits in the United States, from private foundations to corporations seeking to fund grants for nonprofits.

53 Quality of Life Grants in South Carolina over $25K in average grant size

40 Quality of Life Grants in South Carolina over $50K in average grant size

32 Quality of Life Grants in South Carolina supporting general operating expenses

100+ Quality of Life Grants in South Carolina supporting programs / projects

2,000+ Grants on Instrumentl focused on Art & Culture

3,000+ Grants on Instrumentl focused on Education

Grant Deadline Distribution

Over the past year, when are grant deadlines typically due for Quality of Life grants in South Carolina?

Most grants are due in the first quarter.

Q1
28.9%
Q2
25.2%
Q3
24.8%
Q4
21.1%

Typical Funding Amounts

What's the typical grant amount funded for Quality of Life Grants in South Carolina?

Grants are most commonly $15,000.

$500 $500 Min.
$15,000 $15 K Median
$535,356 $535.4 K Average
$40,331,313 $40.3 M Max.

Average Grant Size

What's the typical amount funded for South Carolina?

Grants are most commonly $74,506.

$74,506

Total Number of Grants

What's the total number of grants in Quality of Life Grants in South Carolina year over year?

In 2024, funders in South Carolina awarded a total of 24,410 grants.

2022 21,855

2023 21,722

2024 24,410

Top Grant Focus Areas

Among all the Quality of Life Grants in South Carolina given out in South Carolina, the most popular focus areas that receive funding are Education, Philanthropy, Voluntarism & Grantmaking Foundations, and Human Services.

1. Education

2. Philanthropy, Voluntarism & Grantmaking Foundations

3. Human Services

Funding Over Time

How is funding for Quality of Life Grants in South Carolina changing over time?

Funding has increased by 22.06%.

2022 $1,534,818,247

2023 $1,485,349,233
-3.22%

2024 $1,813,067,383
22.06%

South Carolina Counties That Receive the Most Funding

How does grant funding vary by county?

Greenville County, Richland County, and Charleston County receive the most funding.

County Total Grant Funding in 2024
Greenville County $580,646,902
Richland County $413,417,941
Charleston County $355,724,083
Spartanburg County $325,246,878
Pickens County $159,596,081

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