Upcoming Webinar
How Funders Feel About AI, and What Keeps Them Saying Yes.
Wed, Oct 14 @ 2PM ET

Skip to main content
Main content

Best Grants for Grassroots Organizations in South Dakota

Find the perfect Grants for Grassroots Organizations in South Dakota on Instrumentl. 9,000+ Grants for Grassroots Organizations in South Dakota in the United States.

9,000+

Available grants

$2.62B

Total funding

$5K

Median grant

9,000+ grants
$2.62B total
$5K median

Skip the search. Get matched with grants that fit your non-profit.

Skip the search.

Get matched with grants that actually fit.

Smart recommendations based on your profile — in minutes.

Find me grants

Filters

9,210 Results based on applied filters

The Save Mart Companies CARES Foundation Grant

Save Mart Cares
Private
California, Oregon +2 more
US $500 - US $10,000

About

With deep roots in California’s Central Valley, The Save Mart Companies and its family of stores prides itself in being a part of neighborhoods and putting people first. Our dedication to customers is reflected in the connections we’ve made in the communities we’ve served for more than 70 years.

The Save Mart Companies CARES Foundation

In 2000, we established The Save Mart Companies CARES Foundation, our philanthropic, non-profit organization, supporting programs and organizations that provide vital resources for children and families in the communities we serve. The CARES Foundation focuses on building stronger communities through fresh foods, accessibility, and programs that support youth and helping them to thrive. Annually, The CARES Foundation contributes approximately $500,000 in small grants to support community-based, non-profit organizations.

The Save Mart Companies CARES Foundation Grant

The CARES Foundation’s focus is building stronger communities through fresh foods, access to food, and programs that support youth and helping them thrive.

The CARES Foundation will review, on a quarterly basis, among other things, the breadth of the audience served; the likely impact in the community; the importance of the need to be addressed in the community; and the community reputation, service history, and financial stability of the group or program seeking funds. No one of these or other factors will necessarily be weighted more heavily than another. Instead, each group or program will be measured against all groups and 2 programs seeking funding at the time. For example, a program serving a small segment of the community but that addresses an especially important community need, and thus has the potential for a strong and meaningful impact, would be favored over a group serving a wider clientele but that fills a less important community need. Requests for Grants should be a minimum of $500.00 up to $10,000.00. Programs and organizations requesting smaller grants should contact the Store Manager of the nearest Save Mart Companies’ store location for request consideration.

Recipients that receive grants for more than one year must demonstrate meaningful outcomes for the previous investment made by The CARES Foundation.

Food Access & Hunger Youth Services Family Services +1 more

Corporate Giving - Charitable Contributions

McCormick & Company, Inc
Corporate
United States
Unspecified amount
McCormick & Company, Inc. actively supports charitable contributions through its Charitable Donations Committee (CDC), which prioritizes donations to non-profit organizations that enhance education, health, environment, and culture. The CDC focuses on organizations that benefit communities where McCormick employees live and work, ensuring a positive impact. Eligible groups must be tax-exempt and demonstrate a commitment to non-discrimination. However, donations are not made to individuals, political organizations, or entities that conflict with corporate values.
Environment Art & Culture Health & Medicine +4 more

Impact of Immunotherapies on CNS Outcomes in People with HIV: Potential Benefits, Challenges and Risks

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Up to US $2,000,000
The upcoming National Institute of Mental Health (NIMH) funding opportunity aims to explore the effects of HIV immunotherapies on central nervous system (CNS) outcomes. It seeks to identify mechanisms, benefits, and risks associated with these therapies, focusing on overcoming CNS-specific barriers. The initiative encourages collaborations to develop strategies for achieving sustained virologic remission and improving neurological outcomes for individuals with HIV, particularly targeting neurotoxicity and neuroinflammation.
HIV / AIDS

Single Program Grants

Reader's Digest Partner for Sight Foundation
Private
United States
US $25,000 - US $50,000
The Reader’s Digest Partners for Sight Foundation offers Single Program Grants to support impactful programs for individuals who are blind or visually impaired. These grants, ranging from $25,000 to $50,000, prioritize initiatives that enhance independence and service delivery. Eligible organizations must be US 501(c)(3) non-profits, and unsolicited proposals are not accepted. The foundation emphasizes community-based solutions and invites qualified applicants to submit a Letter of Inquiry followed by a full proposal.
Workforce Preparation & Job Readiness Vision Impairment Care & Services Business Development +1 more

Small Discretionary Grants

Reader's Digest Partner for Sight Foundation
Private
United States
US $5,000 - US $10,000

Reader’s Digest Partners for Sight Foundation

The Reader’s Digest Partners for Sight Foundation is a philanthropic organization dedicated to improving the lives of individuals who are blind or visually impaired by fostering independence and self-sufficiency. Its mission is to support programs that help people with vision loss lead independent, productive lives, while its vision is an accessible and inclusive world where individuals have the tools, resources, and opportunities to fully participate in society.

The Foundation’s funding priorities focus on supporting nonprofit organizations and initiatives that provide education, training, and rehabilitation services, assistive technology innovations, vision care and access to aids, and capacity building for professionals serving the visually impaired community. It also invests in programs that enhance employment opportunities, promote independence, and improve service delivery systems for people with vision loss, emphasizing practical, community-based solutions and long-term impact.

Small Discretionary Grants

The Reader’s Digest Partners for Sight Foundation (RDPFS) Track #3 Small Discretionary Grants provide flexible, year-round funding for smaller-scale initiatives that support individuals who are blind or visually impaired. Grant requests are accepted on a rolling basis and awarded at the discretion of the Executive Director. Awards are made until available funds are exhausted, allowing the Foundation to respond to timely or emerging needs.
Workforce Preparation & Job Readiness Vision Impairment Care & Services Business Development +1 more

Mastercard Innovation Fund

Mastercard Center for Inclusive Growth
Corporate
United States
US $200,000 - US $250,000
The Mastercard Strive USA 2025 Innovation Fund aims to enhance the financial health of small businesses across the U.S. by providing up to $250,000 in grants to organizations developing innovative solutions. This initiative focuses on addressing challenges such as limited access to financial resources and vulnerability to economic shocks, ultimately fostering resilience and growth within the small business sector.
Entrepreneurship Business Education Business Development +2 more

Hays, Karla, Loving Heart, Scholarship

Beatrice Educational Foundation
Association/Society
United States
Up to US $1,000
The Hays, Karla, Loving Heart Scholarship offers financial support to graduating seniors of Beatrice High School, with one to three scholarships available totaling up to $1,000. Administered by the Beatrice Educational Foundation, this initiative aims to assist deserving students in pursuing higher education. The foundation, established in 1987, supports academic achievement and civic involvement in the community. Eligible students must maintain a minimum GPA of 3.0 and demonstrate ethical scholarship application practices.
Education - Higher Education Academic Scholarship Programs Music +2 more

Women's Club of Grand Haven Grant

Grand Haven Area Community Foundation
Private
United States
Unspecified amount
The Women's Club of Grand Haven Grant, established in 2001, offers scholarships to non-traditional students from the Tri-Cities seeking further education. Funded through community efforts such as an annual Used Book Sale, this grant prioritizes financial need and is open to applicants residing in Northern Ottawa County or those who graduated from local school districts. Preference is given to female applicants aged 21 and older, supporting educational advancement for those whose academic journeys have been interrupted.
Education - Higher Education Educational Access & Equity Adult Education +3 more

Jurgens, Virgil, Scholarship

Beatrice Educational Foundation
Association/Society
United States
US $375
The Jurgens, Virgil Scholarship, funded by the Beatrice Educational Foundation, offers a $375 award to a Beatrice High School senior who excels in baseball and ranks in the top 25% of their class. The Foundation, established in 1987, provides financial support for educational opportunities. This scholarship aims to assist deserving students in pursuing higher education, emphasizing the importance of academic achievement and community involvement.
Education - Higher Education Academic Scholarship Programs Baseball & Softball +2 more

Ronald Barnes Memorial Grant

Guild of Carillonneurs in North America
Private
North America
Up to US $14,254
The Ronald Barnes Memorial Grant, offered by The Guild of Carillonneurs in North America, supports North Americans pursuing studies in carillon performance, composition, music history, or instrument design. Established in 1998 to honor Ronald Barnes, a significant figure in carillon music, the grant has awarded over US$140,000 since 2007. For the 2025 cycle, grants of up to US$14,138 are available, depending on the number of successful applicants, promoting education in this unique art form.
Music Classical Music Music Education

Navigator Emergency Department Diversion Models for Non-Urgent Mental Health Concerns (R34 Clinical Trial Required)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Up to US $450,000
This NOFO aims to enhance research on the effectiveness and implementation of family navigation models that divert non-urgent mental health concerns from emergency departments. It will focus on tools for triaging mental health acuity, engaging families with necessary services, and addressing barriers to help-seeking. Important deadlines for grant applications range from February 2025 to October 2027, with optional Letters of Intent encouraged thirty days prior to each due date.
Mental Health & Psychiatric Diseases Children’s Mental Health Emergency Medical Care & Services

Navigator Emergency Department Diversion Models for Non-Urgent Mental Health Concerns (R01 Clinical Trial Required)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Unspecified amount
This grant opportunity from the US Department of Health and Human Services, specifically the National Institutes of Health, aims to examine the effectiveness of family navigation models that divert non-urgent mental health concerns from emergency departments. The initiative seeks to enhance mental health service engagement, provide necessary resources, and support families in overcoming barriers to help-seeking. Key deadlines for applications range from February 2025 to October 2027.
Mental Health & Psychiatric Diseases Children’s Mental Health Emergency Medical Care & Services

Siemens: Sponsorships

Siemens Medical Solutions USA, Inc.
Corporate
United States
Unspecified amount
Siemens Healthineers USA offers sponsorships to support healthcare initiatives across the U.S. They emphasize funding for healthcare organizations and related events, ensuring that requests comply with eligibility criteria. The company prioritizes diagnostic imaging, laboratory diagnostics, cardiology, and oncology. Applications must be submitted at least 45 days prior to the event, and funding is not available for sole sponsorships or certain excluded initiatives. For more information, visit Siemens Healthineers' official site.
Biomedical Imaging Patient Care & Services Cardiovascular Diseases & Systems +1 more

Siemens: Charitable or Product Donations

Siemens Medical Solutions USA, Inc.
Corporate
United States
Unspecified amount
Siemens Healthineers supports charitable donations that align with its focus areas, including diagnostic imaging and oncology. They prioritize well-rated organizations that allocate a significant portion of donations to clinical efforts rather than administrative costs. Events must ensure at least 65% of funds go to the intended cause. Local chapters of national nonprofits should coordinate with their national teams for requests, as Siemens typically does not entertain separate local requests.
Biomedical Imaging Patient Care & Services Cardiovascular Diseases & Systems +1 more

NHLBI SBIR Phase IIB Bridge Awards to Accelerate the Commercialization of Technologies for Heart, Lung, Blood, and Sleep Disorders and Diseases (R44 Clinical Trial Optional) (357230)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Up to US $3,500,000
The NHLBI SBIR Phase IIB Bridge Awards aim to accelerate the commercialization of innovative technologies targeting heart, lung, blood, and sleep disorders. This funding supports small businesses in later-stage research and development, bridging the gap between SBIR Phase II awards and commercialization. Projects must align with NHLBI's mission and demonstrate potential for clinical relevance, emphasizing partnerships with investors to secure necessary funding for regulatory approval.
Medical Technology, Devices, and Equipment Cardiovascular Diseases & Systems Hematological Systems +2 more

Single Cell Opioid Responses in the Context of HIV (SCORCH) Program: Phase 2

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The SCORCH Program: Phase 2 aims to enhance the understanding of single cell biology in the context of HIV and Substance Use Disorder (SUD). Building on previous research, this initiative will explore new single cell approaches to investigate the interactions between SUD and HIV progression at various biological levels. By leveraging advanced techniques, the program seeks to identify candidate mechanisms and potential therapeutic targets, ultimately contributing to innovative solutions for SUDs and HIV-related challenges.
HIV / AIDS

NHLBI SBIR Phase IIB Small Market Awards to Accelerate the Commercialization of Technologies for Heart, Lung, Blood, and Sleep Disorders and Diseases (R44 Clinical Trial Optional) (357231)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Up to US $3,500,000
The NHLBI SBIR Phase IIB Small Market Awards aim to bridge the funding gap for small businesses developing technologies for heart, lung, blood, and sleep disorders. This initiative supports later-stage research and development for projects addressing rare diseases or pediatric populations. By promoting partnerships with investors and advocacy organizations, the program seeks to facilitate regulatory approval and commercialization of innovative biomedical solutions, ultimately enhancing public health outcomes.
Medical Technology, Devices, and Equipment Cardiovascular Diseases & Systems Hematological Systems +2 more

F26AS00071 Cooperative Endangered Species Conservation Fund: Habitat Conservation Plan Land Acquisition Grants

US Department of the Interior: Fish and Wildlife Service (FWS)
Federal Government
American Samoa, Guam +4 more
US $10,000 - US $26,000,000
The Cooperative Endangered Species Conservation Fund supports habitat conservation through land acquisition grants. Established in 1997, this program aims to minimize conflicts between listed species conservation and land use. The U.S. Fish and Wildlife Service provides matching grants to state agencies for projects that ensure the long-term protection of habitats. By acquiring land or conservation easements, this initiative facilitates species recovery and helps prevent future listings under the Endangered Species Act, enhancing overall ecosystem health.
Environmental Conservation Habitat & Ecosystem Restoration Land / Habitat Conservation

F26AS00105 National Fish Passage Program

Fish and Wildlife Service
Federal Government
American Samoa, Guam +4 more
Up to US $1,000,000
The National Fish Passage Program (NFPP) offers vital assistance for removing barriers to aquatic life, enhancing safety, and promoting local economies. By investing in projects like culvert replacements and floodplain restorations, the program not only supports native fish populations but also delivers significant economic benefits, estimated at $1.5 million for every $1 million invested. With a recent allocation of $15 million, including $5 million for specific restoration initiatives, NFPP continues to advance aquatic connectivity nationwide.
Habitat & Ecosystem Restoration Ichthyology (Fish) Fish Conservation

Charles and Joan Hermanowski Family Foundation Grant

Charles And Joan Hermanowski Family Foundation Inc
Private
United States
Up to US $10,000
The Charles and Joan Hermanowski Family Foundation aims to enhance the lives of children and young adults in the U.S. by providing financial support to 501(c)(3) organizations focused on arts, education, health, and welfare. Grants, capped at $10,000, must be utilized within one year and are not automatically renewable. The foundation seeks to support smaller charities that may not receive broad public backing, thus creating a more significant impact on individual communities.
Youth Development & Leadership Youth Involvement in the Arts Youth Services +3 more

Special Wildlife Funds - Duck Stamp Grants - Canada

Canada Department Of Natural Resources
State/Local Government
Canada, United States
Up to US $500,000
The Special Wildlife Funds - Duck Stamp Grants program in Canada focuses on the development of waterfowl propagation areas specifically for the Mississippi Flyway. It supports projects in Manitoba and Saskatchewan aimed at enhancing breeding populations of migratory waterfowl. This initiative is funded through the sale of State Migratory Waterfowl Stamps and is targeted at not-for-profit organizations dedicated to the conservation and promotion of wild waterfowl, ensuring sustainable habitats and effective management practices.
Water Resource Management

CFF Innovation Grants

COLIN FARRELL FOUNDATION
Private
United States
US $10,000 - US $50,000

About Colin Farrell FoundationThe Colin Farrell Foundation is committed to transforming the lives of individuals and families living with intellectual disability through education, awareness, advocacy, and innovative programs. Inspired by his two sons, he is excited and deeply humbled by the hope that the Colin Farrell Foundation can help those who the larger systems of governance have neglected.

CFF Innovation GrantsWe’re looking for bold, scalable solutions focused on one or more of these priority areas:

  • Affordable co-housing models for individuals and families
  • Employer-partnered day programs and inclusive job opportunities
  • Tools and technologies that enhance accessibility at home and in community spaces
  • Cross-sector collaborations between public, private, and nonprofit organizations

Intellectual / Developmental Disabilities Equitable & Affordable Housing Volunteerism & Philanthropy

Survivorship and Supportive Care Research Grant

St Baldricks Foundation Inc
Private
United States
Up to US $50,000

St. Baldrick's Foundation

The St. Baldrick's Foundation is a volunteer and donor powered charity committed to supporting the most promising research to find cures for childhood cancers and give survivors long and healthy lives. It started with a friendly dare: would you shave your head to raise money for kids’ cancer research? What happened next would change the world. This bold act of baldness has gained major momentum, since its start in 2000. Today, we have more than 1,000 head-shaving events taking place around the world at pubs, restaurants, schools, churches, parks, firehouses, military bases – you name it. It is our constituents’ way of changing the world, in a meaningful way. Volunteers also raise funds through athletic challenges, livestream fundraisers and many other activities.

Since the Foundation's first grants as an independent charity in 2005, St. Baldrick's has invested more than $380 million in childhood cancer research grants worldwide.

About Allied World

Allied World Assurance Company Holdings, Ltd, through its subsidiaries, is a global provider of insurance and reinsurance solutions. The company operates under the brand Allied World and has supported clients, cedents and trading partners with thoughtful service and meaningful coverages since 2001. Since the inception of St. Baldrick’s, Allied World has supported childhood cancer research through the Foundation, and it is the largest of many reinsurance company sponsors, making this life-saving mission a top priority.

Survivorship and Supportive Care Research Grant

These grants are for specific one-year research projects which are hypothesis-driven and focus on areas related to survivorship and supportive care of children and adolescents with cancer. Examples include but are not limited to: studies related to the burden of morbidity, cause-specific mortality, understanding the pathogenesis of treatment-related complications, patient-reported outcomes or quality of life, health communication, health promotion, and psychosocial support across the trajectory from diagnosis to survivorship or end-of-life care.

Projects must have direct applicability and relevance to pediatric cancer. They may be in any discipline of basic, clinical, translational, or epidemiological research.

Cancer / Oncology Pediatric Cancers Patient Care & Services

IDNR: State Duck Stamp Funding

Illinois Department of Natural Resources
State/Local Government
Canada, United States
Up to US $500,000
The IDNR: State Duck Stamp Funding program supports the development of waterfowl propagation areas in the Mississippi Flyway. Funded by sales of State Migratory Waterfowl Stamps, it focuses on projects in Canada and the U.S. that enhance waterfowl populations. Eligible applicants include not-for-profit organizations aiming to implement the North American Waterfowl Management Plan. This initiative not only fosters wildlife conservation but also strengthens ecological sustainability in the region.
Habitat & Ecosystem Restoration Land / Habitat Conservation Ornithological Conservation

Never Let Go Fund

Emporia Community Foundation
Private
United States
Up to US $2,000

About the Emporia Community Foundation

Our Mission

To connect caring people with causes that build stronger communities within the Emporia area which includes Chase, Coffey, Greenwood, Lyon, Morris, Osage and Wabaunsee counties.

Never Let Go Fund

The purpose of the Never Let Go Fund is to provide funds to qualified individuals to cover expenses related to the treatment of childhood cancer. Grant requests will be considered for children under the age of 18.

Health Care Access & Delivery Cancer / Oncology Children’s Health & Pediatrics +1 more

CCRP Initiative: NIH Countermeasures Against Chemical Threats (CounterACT) Basic Research on Chemical Threats that Affect the Nervous System (R01 Clinical Trial Not Allowed) (356935)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Up to US $300,000
The CCRP Initiative invites applications for basic research on chemical threats affecting the nervous system, including chemical warfare agents and toxic industrial chemicals. This funding aims to elucidate toxicity mechanisms, explore new toxic exposure manifestations, and identify targets for therapeutic development. Proposals should generate data relevant to understanding these toxic threats, with applications due by 5 PM local time. Optional Letters of Intent are encouraged 30 days prior to the proposal deadline.
Neuroscience Environmental Chemistry & Toxicology Neurological Diseases & Disorders

Capacity Building for National Immunization Programs in the Eastern Mediterranean Region (363749)

Dept. of Health & Human Services: Centers for Disease Control & Prevention
Federal Government
American Samoa, Guam +4 more
Unspecified amount
This grant aims to enhance national immunization programs in the Eastern Mediterranean Region by focusing on capacity building, disease control, and outbreak response. It seeks to eliminate vaccine-preventable diseases, reduce morbidity and mortality, and improve access for under-immunized populations. The initiative will promote sustainability through evidence-based decision-making and program evaluation, aligning with CDC goals to address public health threats and improve overall immunization impact in the region.
Epidemiology & Public Health Infectious & Parasitic Diseases Health Care Access & Delivery +2 more

Grants for Grassroots Organizations in South Dakota Highlights

Looking for grants for grassroots organizations in South Dakota?


Read more about each grant below or start your 14-day free trial to see all grants for grassroots organizations in South Dakota recommended for your specific programs.

Last updated: October 5, 2026. Next update: November 1, 2026.

Grant Insights : Grants for Grassroots Organizations in South Dakota

Grant Availability

How common are grants in this category?

Uncommon — grants in this category are less prevalent than in others.

100+ Grants for Grassroots Organizations in South Dakota grants for nonprofits in the United States, from private foundations to corporations seeking to fund grants for nonprofits.

30 Grants for Grassroots Organizations in South Dakota over $25K in average grant size

23 Grants for Grassroots Organizations in South Dakota over $50K in average grant size

23 Grants for Grassroots Organizations in South Dakota supporting general operating expenses

91 Grants for Grassroots Organizations in South Dakota supporting programs / projects

600+ Grants on Instrumentl focused on Food Access & Hunger

1,000+ Grants on Instrumentl focused on Workforce Preparation & Job Readiness

Grant Deadline Distribution

Over the past year, when are grant deadlines typically due for grants for Grassroots Organizations in South Dakota?

Most grants are due in the first quarter.

Q1
34.7%
Q2
24.6%
Q3
19.8%
Q4
21.0%

Typical Funding Amounts

What's the typical grant amount funded for Grants for Grassroots Organizations in South Dakota?

Grants are most commonly $10,000.

$250 $250 Min.
$10,000 $10 K Median
$89,650 $89.7 K Average
$1,250,000 $1.3 M Max.

Average Grant Size

What's the typical amount funded for South Dakota?

Grants are most commonly $110,621.

$110,621

Total Number of Grants

What's the total number of grants in Grants for Grassroots Organizations in South Dakota year over year?

In 2024, funders in South Dakota awarded a total of 6,460 grants.

2022 6,268

2023 6,140

2024 6,460

Top Grant Focus Areas

Among all the Grants for Grassroots Organizations in South Dakota given out in South Dakota, the most popular focus areas that receive funding are Education, Human Services, and Philanthropy, Voluntarism & Grantmaking Foundations.

1. Education

2. Human Services

3. Philanthropy, Voluntarism & Grantmaking Foundations

Funding Over Time

How is funding for Grants for Grassroots Organizations in South Dakota changing over time?

Funding has increased by 17.48%.

2022 $638,830,994

2023 $606,495,212
-5.06%

2024 $712,509,384
17.48%

South Dakota Counties That Receive the Most Funding

How does grant funding vary by county?

Minnehaha County, Lake County, and Pennington County receive the most funding.

County Total Grant Funding in 2024
Minnehaha County $176,653,145
Lake County $117,647,066
Pennington County $90,630,616
Brookings County $75,457,854
Todd County $56,559,538