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Best Grants for New Nonprofits in South Dakota

Find the perfect Grants for New Nonprofits in South Dakota on Instrumentl. 9,000+ Grants for New Nonprofits in South Dakota in the United States.

9,000+

Available grants

$2.62B

Total funding

$5K

Median grant

9,000+ grants
$2.62B total
$5K median

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9,206 Results based on applied filters

NIH StrokeNet Clinical Trials and Biomarker Studies for Stroke Treatment, Recovery, and Prevention (UG3/UH3 Clinical Trial Optional) (357256)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The NIH StrokeNet initiative invites applications for clinical trials and biomarker studies aimed at stroke treatment, recovery, and prevention. This funding opportunity encourages collaborative projects that validate promising interventions and scientific aims within the NIH StrokeNet framework. Key deadlines for submissions span from February 2025 to November 2026, with support provided by the National Coordinating Center and Regional Coordinating Centers to ensure efficient study implementation and participant recruitment.
Stroke

Capacity Building for Global, Regional, and National Immunization Programs (363591)

Dept. of Health & Human Services: Centers for Disease Control & Prevention
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The Capacity Building for Global, Regional, and National Immunization Programs aims to enhance immunization efforts in key countries, focusing on the prevention and control of vaccine-preventable diseases like polio and measles. By strengthening immunization services and surveillance systems, the program will better address emerging health threats and reach under-immunized populations. Additionally, it will support sustainable practices through National Immunization Technical Advisory Groups and manage the National Stop Transmission of Polio program in Pakistan.
Preventative Healthcare Vaccines & Immunizations

PCRF: Translational Research Grant

Pediatric Cancer Research Foundation
Private
United States
Up to US $100,000
The Pediatric Cancer Research Foundation (PCRF) is dedicated to funding innovative research aimed at curing childhood cancer. With a focus on collaborative efforts, PCRF has contributed over $51 million since 1982, significantly improving survival rates for childhood cancers. The Translational Research Grant supports cutting-edge clinical trials and therapeutic approaches, enhancing the journey from laboratory discoveries to patient care. This initiative underscores the urgent need for effective treatments, offering hope for children diagnosed with cancer and their families.
Pediatric Cancers

Applied regulatory science research to evaluate and treat cardiotoxicity of oncology therapeutics

US Department of Health & Human Services: Food and Drug Administration (FDA)
Federal Government
United States
Unspecified amount
This grant aims to enhance applied regulatory science research for the evaluation and treatment of cardiotoxicity associated with oncology therapeutics. The initiative will facilitate collaboration with the FDA to develop effective methodologies and solutions, ensuring that research outcomes are directly relevant to regulatory decision-making. Key activities include regular communication with funded investigators and a focus on improving detection and management of cardiotoxicity, ultimately leading to impactful publications and presentations.
Cancer / Oncology Drug Safety

Robert C. Weaver Memorial Scholarship Fund

Idaho Community Foundation (ICF)
Private
United States
Unspecified amount

Idaho Community Foundation

The Idaho Community Foundation distributes millions annually in grants and scholarships across the state. These awards are made possible by individuals, families, businesses, affiliates, giving circles, and everyday Idahoans who care for their community.Robert C. Weaver Memorial Scholarship FundEstablished by Neola Weaver in memory of her late husband, residents or former residents of Buhl are eligible for scholarship support as either traditional or nontraditional students. For part-time or full-time traditional or nontraditional students pursuing post high school vocational or academic training. 

Education - Higher Education College Success / Persistence Vocational & Trade Education

ADDF-Harrington Scholar Program

Alzheimers Drug Discovery Foundation
Private
Canada, United Kingdom +1 more
Up to US $600,000
The ADDF-Harrington Scholar Program aims to transform academic discoveries into effective treatments for Alzheimer’s disease and related dementias. With funding of up to $600,000 annually, this program prioritizes innovative drug targets and supports research from hit-to-lead optimization to IND-enabling studies. Eligible applicants include academic investigators with a strong potential to advance meaningful therapeutics. The program emphasizes collaboration with industry experts, making it a significant opportunity for advancing dementia research.
Dementia & Alzheimer’s Disease

NEI Postbaccalaureate Opportunities in Vision Science (POVS) Research Education Program (R25 Clinical Trial Not Allowed)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Up to US $2,000,000
The NEI Postbaccalaureate Opportunities in Vision Science (POVS) Research Education Program aims to enhance the training of a diverse workforce in biomedical research. This NIH-funded initiative focuses on providing intensive, hands-on research experiences for recent college graduates from various backgrounds, preparing them for doctoral programs in biomedical fields. The program encourages participation from individuals without prior research opportunities in vision sciences, fostering a nationally recruited cohort for substantial impact in the field.
Eye Diseases & Disorders Vision Impairment Care & Services

Trans Justice Funding Project Grants

Trans Justice Funding Project
Association/Society
American Samoa, Guam +4 more
Unspecified amount
The Trans Justice Funding Project (TJFP) provides grants to grassroots trans-led organizations in the U.S. and territories, focusing on those with budgets under $250,000. TJFP supports initiatives that address varying needs within trans communities, including health, legal aid, and mutual aid projects. The organization prioritizes groups led by trans people of color and emphasizes the importance of centering marginalized voices in the fight for trans justice.
Intersex & Transgender Rights

Alzheimer's Drug-Development Program (U01 Clinical Trial Optional)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The National Institute on Aging (NIA) is inviting applications for the Alzheimer's Drug-Development Program (U01 Clinical Trial Optional). This initiative seeks to support pre-clinical and early-stage clinical development of innovative drug candidates aimed at preventing Alzheimer's disease or treating its symptoms. The program encourages collaboration among researchers and aims to enhance the therapeutic pipeline for AD through targeted approaches. This notice allows potential applicants time to prepare robust projects.
Dementia & Alzheimer’s Disease

Shubert Foundation: Arts Related Organizations Grants

The Shubert Foundation
Private
United States
Unspecified amount
The Shubert Foundation provides unrestricted grants to not-for-profit professional theatre and dance companies in the U.S. Its focus is on organizations with a proven track record in artistic and administrative excellence. Eligible applicants must have a minimum annual budget of $150,000 and demonstrate financial stability, strong community engagement, and the ability to generate income. The foundation does not fund individuals, project-specific requests, or organizations without 501(c)(3) status.
Theater Dance

Jim & Betty Lilly Scholarship Fund

Stanislaus Community Foundation
Private
United States
US $1,000

Stanislaus Community Foundation provides scholarship opportunities for students in order to help them achieve their educational and career goals. We believe that by investing in our students, we are investing in a brighter future for Stanislaus.

Jim & Betty Lilly Scholarship Fund

Open to students from Stanislaus and Calaveras County who have attended a continuation high school, including those who have returned to and graduated from traditional high schools or attending a Vocational School.

Award Amount:

  • $1,000
Education - Higher Education Career / College Preparation Vocational & Trade Education

Aim High Grant Program: One-Year Grants

New York Life Foundation
Corporate
United States
US $20,000
The Aim High Grant Program offers one-year grants of $20,000 to support out-of-school time programs for middle school youth. Funded by the New York Life Foundation, this initiative aims to enhance students' transition to high school by providing essential skills and guidance. Programs must demonstrate effective engagement strategies and serve low-income communities. This grant represents a vital investment in the future of young people, helping them develop academically, socially, and emotionally.
After School / Summer Educational Programs Education - Middle School

Terry Linda Potter Scholarship

Grand Haven Area Community Foundation
Private
United States
Unspecified amount
The Terry Linda Potter Scholarship, awarded by the Grand Haven Area Community Foundation, supports students from Northwest Ottawa County pursuing health-related degrees. Established in memory of Terry Linda Potter, this scholarship prioritizes financial need and academic performance. Applicants must demonstrate a commitment to further education and submit necessary documentation, including transcripts and recommendation letters. This fund honors Terry's legacy, providing vital financial assistance to aspiring healthcare professionals in the Tri-Cities area.
Education - Higher Education Educational Access & Equity Medical Education & Professional Training

VFW Post 2326 Ward-Goff Memorial Scholarship

Grand Haven Area Community Foundation
Private
United States
Unspecified amount
The VFW Post 2326 Ward-Goff Memorial Scholarship, established by Mr. and Mrs. Elgin Ward and Mr. and Mrs. Richard Goff, honors their sons who served in the Vietnam War. This scholarship provides financial assistance to children and grandchildren of active military personnel and veterans. Applicants must maintain a minimum 3.0 GPA and submit necessary documents, including transcripts. The scholarship emphasizes financial need and aims to support outstanding students pursuing their educational goals.
Education - Higher Education Educational Access & Equity Military & Veterans Services

Friends of Reservoirs: Small Grant

Friends of Reservoirs
Private
United States
More than US $3,500
The Friends of Reservoirs: Small Grant program offers annual grants of $2,000 to member organizations of Friends of Reservoirs, with additional product donations bringing the total value over $3,500. This initiative, supported by generous sponsors, aims to enhance reservoir fisheries habitats. Applicants should note a $25 application fee, which contributes directly to the grant fund. This program focuses on fostering community engagement and improving aquatic ecosystems.
Fisheries

CART Fund Grant

CART Fund
Private
United States
Up to US $500,000
The CART Fund Grant supports innovative Alzheimer’s Disease research projects in the U.S. with funding up to $500,000 for a two-year period. It invites full-time faculty from public and private institutions to submit Letters of Intent, emphasizing novel concepts that advance biomedical knowledge. Selected finalists will be invited to apply for standard grants. The initiative aims to foster groundbreaking research initiatives lacking extensive preliminary data, ensuring a focus on projects with transformative potential.
Dementia & Alzheimer’s Disease

Tucker Baptist Association Scholarship

Community Foundation of South Georgia
Private
United States
Unspecified amount

Who We Are

Founded in 1996, the Community Foundation of South Georgia is a 501(c)(3) nonprofit organization committed to making South Georgia a better place to live through effective philanthropy. We help individuals, families, nonprofit organizations and businesses establish and manage charitable funds that carry out their philanthropic interests. Serving a geographic area of 35 counties in South Georgia, we facilitate our donors’ charitable plans and goals by creating custom designed funds that meet their specific interests and ensure solid financial management and administration for each fund. 

Tucker Baptist Association Scholarship

For a high school graduate who is also a member of a church which is part of the Tucker Baptist Association. The applicant must be enrolled in a seminary, Bible college, or other educational institution where they are training for a Christian gospel ministry vocation. This may include but is not limited to, training as a pastoral minister, youth minister, music minister, educational minister, or foreign or home missionary. The training may be a degree program such as a Masters of Divinity, etc., or the training may be a seminar or educational course related to ministry development.

Education - Higher Education Baptist Faith Religious / Theological Education

Classics for Kids Matching Grant Program

Classics for Kids
Private
United States
Unspecified amount
The Classics for Kids Matching Grant Program, established by the Classics for Kids Foundation, aims to enhance music education for at-risk and rural youth by providing matching grants for fine stringed instruments. Since 1998, over $2 million has been allocated to support more than 300 programs across all 50 states. Schools and non-profits demonstrating need and commitment are encouraged to apply, fostering lifelong benefits of music participation and education.
Classical Music

LUNGevity Career Development Award

LUNGevity Foundation Inc
Private
United States
US $100,000 - US $300,000
The LUNGevity Career Development Award supports emerging research leaders focused on lung cancer. It funds innovative projects aimed at enhancing early detection and personalized treatments, including targeted therapies and immunotherapy. With a maximum award of $300,000 over three years, this opportunity is limited to US applicants. The funding is contingent upon annual progress reviews, with the first payment expected after November 1, 2025. This award aims to foster groundbreaking advancements in lung cancer research.
Lung Cancer

Integration of Imaging and Fluid-Based Tumor Monitoring in Cancer Therapy (R01 Clinical Trial Optional) (357003)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Up to US $2,500,000
The Integration of Imaging and Fluid-Based Tumor Monitoring in Cancer Therapy (R01 Clinical Trial Optional) aims to enhance cancer treatment by integrating imaging and liquid biopsy assays. This initiative, led by the National Cancer Institute (NCI), encourages grant applications focused on assessing therapy responses and resistance emergence in patients. Key deadlines for submissions span from February 2025 to January 2028, providing ample opportunities for researchers to contribute to this vital area of cancer research.
Cancer / Oncology Biomedical Imaging

AHS Investigator-Initiated Research Awards

American Headache Society (AHS)
Association/Society
United States
Up to US $50,000

American Headache Society

The American Headache Society (AHS) is a professional society of healthcare providers dedicated to the study and treatment of headache and face pain. The Mission of the AHS is to improve the lives of people impacted by migraine and other headache disorders. AHS advocates for those impacted by headache and the headache field, to meet our core objectives. AHS provides educational courses, scientific meetings, a journal, research support, career development opportunities, Special Interest Groups, advocacy training, and a professional community. The AHS strives to meet its objectives while fostering an inclusive sense of belonging and community.

AHS Investigator-Initiated Research Awards

Empowering Innovation in Headache Research

The American Headache Society (AHS) Investigator-Initiated Research Awards support AHS members conducting pre-clinical and clinical research in headache and migraine. With a focus on early-career investigators, the program funds investigator-driven projects that advance scientific understanding and improve patient care.

Projects should contribute to the core goal of the AHS – improving the lives of people impacted by migraine and other headache disorders. 

Funding may be used for:

  • Investigator effort (limited to 25% of the budget for PI salary support).
  • Experimental costs, data collection, supplies, and statistical analysis.
  • Other research-related expenses as appropriately justifie
Neurological Diseases & Disorders Chronic / Acute Pain

Molecular Imaging of Inflammation in Cancer (R01 Clinical Trial Not Allowed) (357002)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Up to US $2,500,000
This funding opportunity invites applications for R01 grants focused on molecular imaging methods to explore cancer inflammation in vivo. It aims to enhance understanding of dynamic interactions between inflammation and cancer through innovative imaging techniques. The initiative encourages collaborations between cancer researchers and imaging scientists to leverage molecular imaging for identifying cellular physiology changes in response to treatment. Deadline dates for applications range from February 2025 to October 2027, emphasizing timely submission for prospective researchers.
Cancer / Oncology Biomedical Imaging

Kent A. & Diana C. Morgan Family Scholarship

Marion Community Foundation
Private
United States
Unspecified amount

Marion Community Foundation

Since 1998, area residents have been turning to Marion Community Foundation to make their philanthropic giving as effective as possible. We are a public charity serving thousands of people who share a common concern … improving the quality of life in Marion County. We use distributions from the more than 500 charitable funds — created by generous, local donors — to award more than $2.5 million in grants and scholarships each year to many of the humanitarian, educational and cultural organizations in this remarkable community we call home.

Marion Community Foundation is the area’s leading philanthropic organization, providing charitable donors the opportunity to easily create endowment funds to benefit and support our community through grants and scholarships. We serve communities throughout Marion County through philanthropy, leadership, and civic engagement.

Kent A. & Diana C. Morgan Family Scholarship

The Kent A. & Diana C. Morgan Family Scholarship Fund was established in 2019 as a legacy fund. It will provide scholarships for Marion County high school seniors and graduates pursuing a degree in the field of education, with special consideration given to applicants who demonstrate, through the applicant’s application, extraordinary financial need.

Academic Scholarship Programs College Success / Persistence Education - Higher Education

AHS Headache & Migraine Competitive Grant Program - Adult Population RFP

American Headache Society (AHS)
Association/Society
Canada, United States
Up to US $250,000

American Headache Society

The American Headache Society (AHS) is a professional society of healthcare providers dedicated to the study and treatment of headache and face pain. The Mission of the AHS is to improve the lives of people impacted by migraine and other headache disorders. AHS advocates for those impacted by headache and the headache field, to meet our core objectives. AHS provides educational courses, scientific meetings, a journal, research support, career development opportunities, Special Interest Groups, advocacy training, and a professional community. The AHS strives to meet its objectives while fostering an inclusive sense of belonging and community.

Headache & Migraine Competitive Grant Program

The Headache & Migraine Competitive Grant Program stands at the forefront of advancing headache medicine by funding groundbreaking quality improvement initiatives. This highly competitive grant program, offered through the collaboration between the American Headache Society and Pfizer, supports projects that have the potential to reshape the field by creating widely applicable tools and driving measurable improvements in patient care. 

Adult Population  RFP (Quality Improvement Solutions for the Diagnosis and Management of Migraine and Headache Disorder)

Seeking projects that drive meaningful impact in headache care through advancements in safety, clinical effectiveness, timely diagnosis, and equitable, patient-centered treatment. Submissions should feature bold, practical solutions in primary care and non-headache specialty settings, supporting adult populations with scalable, real-world innovations. 

Chronic / Acute Pain Neurological Diseases & Disorders

Beattie Family Foundation: Educational Scholarship

Beattie Family Foundation
Private
United States
US $2,000 - US $5,000
The Beattie Family Foundation offers educational scholarships aimed primarily at medical and nursing students facing financial challenges. These scholarships, ranging from $2,000 to $5,000, support individuals currently enrolled in accredited institutions who demonstrate strong academic capabilities. Additionally, limited funds are available for vocational or trade school tuition for those aspiring to enter skilled labor professions. The foundation prioritizes applicants based on financial need and academic performance.
Nursing Medical Education & Professional Training Vocational & Trade Education

NIDCD Research Dissertation Fellowship for Au.D. Audiologists (F32) (358114)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The NIDCD Research Dissertation Fellowship for Au.D. Audiologists (F32) supports rigorous biomedical research training and dissertation research for doctoral candidates in clinical, behavioral, or biomedical sciences. Funded by the NIH, this fellowship aims to enhance research capabilities and knowledge in the field of audiology. Key deadlines for applications include April 8, August 8, and December 8 for the years 2025 to 2027, ensuring timely opportunities for aspiring researchers.
Hearing Disorders & Audiology

AMD Resident Research Grant

Association of Migraine Disorders (AMD)
Association/Society
United States
Up to US $12,000
The AMD Resident Research Grant aims to foster innovative research projects related to migraine, encouraging residents to explore diverse topics that are scientifically sound. Applicants, who must be enrolled in accredited training programs, can collaborate with preceptor investigators and receive support from their institutions. The grant is open to all residents without country restrictions, promoting advancements in migraine understanding and treatment.
Neurological Diseases & Disorders Neuroscience

Grants for New Nonprofits in South Dakota Highlights

Looking for grants for new nonprofits in South Dakota?


Read more about each grant below or start your 14-day free trial to see all grants for new nonprofits in South Dakota recommended for your specific programs.

Last updated: October 5, 2026. Next update: November 1, 2026.

Grant Insights : Grants for New Nonprofits in South Dakota

Grant Availability

How common are grants in this category?

Uncommon — grants in this category are less prevalent than in others.

100+ Grants for New Nonprofits in South Dakota grants for nonprofits in the United States, from private foundations to corporations seeking to fund grants for nonprofits.

30 Grants for New Nonprofits in South Dakota over $25K in average grant size

23 Grants for New Nonprofits in South Dakota over $50K in average grant size

23 Grants for New Nonprofits in South Dakota supporting general operating expenses

91 Grants for New Nonprofits in South Dakota supporting programs / projects

3,000+ Grants on Instrumentl focused on Education

2,000+ Grants on Instrumentl focused on Human & Social Services

Grant Deadline Distribution

Over the past year, when are grant deadlines typically due for grants for New Nonprofits in South Dakota?

Most grants are due in the first quarter.

Q1
34.7%
Q2
24.6%
Q3
19.8%
Q4
21.0%

Typical Funding Amounts

What's the typical grant amount funded for Grants for New Nonprofits in South Dakota?

Grants are most commonly $10,000.

$250 $250 Min.
$10,000 $10 K Median
$89,650 $89.7 K Average
$1,250,000 $1.3 M Max.

Average Grant Size

What's the typical amount funded for South Dakota?

Grants are most commonly $110,621.

$110,621

Total Number of Grants

What's the total number of grants in Grants for New Nonprofits in South Dakota year over year?

In 2024, funders in South Dakota awarded a total of 6,460 grants.

2022 6,268

2023 6,140

2024 6,460

Top Grant Focus Areas

Among all the Grants for New Nonprofits in South Dakota given out in South Dakota, the most popular focus areas that receive funding are Education, Human Services, and Philanthropy, Voluntarism & Grantmaking Foundations.

1. Education

2. Human Services

3. Philanthropy, Voluntarism & Grantmaking Foundations

Funding Over Time

How is funding for Grants for New Nonprofits in South Dakota changing over time?

Funding has increased by 17.48%.

2022 $638,830,994

2023 $606,495,212
-5.06%

2024 $712,509,384
17.48%

South Dakota Counties That Receive the Most Funding

How does grant funding vary by county?

Minnehaha County, Lake County, and Pennington County receive the most funding.

County Total Grant Funding in 2024
Minnehaha County $176,653,145
Lake County $117,647,066
Pennington County $90,630,616
Brookings County $75,457,854
Todd County $56,559,538