Best Operating Grants for Nonprofits in South Dakota

The CareQuest Emergent & Relief Fund aims to address the unique challenges faced by historically underserved communities in the healthcare system, particularly in oral health. This fund supports innovative approaches, urgent clinical responses, and immediate relief efforts for community crises. Grants are targeted at organizations demonstrating commitment to equity in health services, ensuring that aid reaches those most in need. With a focus on transformative change, this initiative seeks to enhance access and improve health outcomes across diverse populations.

Tom and Betty Herold Scholarship

This scholarship is made possible by the generosity of Thomas M. and Elizabeth L. Herold.

The Herold Scholarship is to be awarded to high school graduate(s) from a Randolph County, Indiana high school. The scholarship is awarded annually to one of the high schools on a rotational basis in the following order (or in the school consolidated), and then repeated: Randolph Central School Corporation (Winchester Community High School), Randolph Eastern School Corporation (Union City Jr./Sr. High School), Randolph Southern School Corporation, Monroe Central Jr./Sr. High School, Union School Corporation. Students must be pursuing a two- or four- year secondary degree.

The Medical Student Research Award, funded by the American College of Gastroenterology, offers U.S. and Canadian medical students a unique opportunity for summer research experiences in gastroenterology and hepatology. This award promotes interest in these fields through mentored projects, covering living expenses and travel to the ACG Annual Scientific meeting. Since 1994, over $31.89 million has been awarded, supporting more than 745 recipients, making it a vital program for aspiring researchers.

The NIH Common Fund is launching the RNomics program to advance RNA research through innovative technologies. This initiative focuses on developing tools for comprehensive analysis of RNA molecules, addressing current methodological limitations. Key priorities include sequencing RNA, detecting modifications, and studying RNA function across various biological contexts. The program encourages high-risk, early-stage projects that demonstrate potential for significant impact. Successful Phase 1 projects may transition to Phase 2, aimed at delivering validated resources for the research community.

Alice O. Rydell Interior Design Scholarship

Graduating senior or graduating early college student who attends public, private, or home school in the primary service area of the Community Foundation.

Foundation

The Bureau County Farm Bureau Foundation was established in 1991 by members of the Bureau County Farm Bureau. The mission of the Farm Bureau Foundation is “To carry out charitable, scientific, literary and educational work that benefits Bureau County farm families and agriculture.”

The Foundation supports agricultural programs aimed at:

• Scholarship
• Education
• Leadership
• Research

Bureau County College Student Agricultural Scholarship

To provide for persons studying agriculture and agriculture-related fields including but not limited to education, vet medicine, and leadership development.

The Community Foundation of Shelby County

Our Mission

To inspire donor generosity and transform it into meaningful, lasting impact through charitable gifts.

Our Vision

To be the primary partner for donors who want to advance the community’s quality of life and capacity for excellence.

Betty Lee Riggs Hughes Nursing Scholarship

A Shelby County resident pursuing a Registered Nursing degree. 

Selection based upon (in order of priority):

• Demonstrate the empathy, compassion, and requisite patience in order to enjoy and devote oneself to a long and fruitful nursing career, financial need, academic ability, recommendations, demonstrated community and school service.

Awards

• One $1,000 scholarship

William C. and Anna Rose Chamberlain Memorial

The fund was established in 1926 "for the propagation of the Gospel of Jesus Christ," to be used to educate those interested in the ministry; or as a missionary; or ordained professional minister of the Christian Church (Disciples of Christ); or for some definite religious work in connection with the church. Priority is given to members or former members of Gender Road Christian Church (formerly known as Southeast Christian Church).

Award Amount:

• Minimum $500

The Community Foundation of Shelby County

Our Mission

To inspire donor generosity and transform it into meaningful, lasting impact through charitable gifts.

Our Vision

To be the primary partner for donors who want to advance the community’s quality of life and capacity for excellence.

Catherine Moloney Nursing Scholarship

A Shelby County resident pursuing a Registered Nursing degree. 

Selection based upon:

• Financial need; academic ability; demonstrated “empathy which is necessary, the compassion which is required, and the requisite patience in order to enjoy and devote oneself to a long and fruitful nursing career.”

Awards

• One $1,000 scholarship

The Clifford D. Grim and Virginia S. Grim Educational Fund offers scholarships to deserving students from Winchester/Frederick and Clark Counties, VA. Facilitated by the Center for Scholarship Administration, Inc., the fund provides financial support for students enrolled full-time in accredited colleges. Applicants must demonstrate financial need and have a minimum GPA of 2.5. Scholarships are renewable for up to four years, contingent upon reapplication each year.

The Community Foundation of Shelby County

Our Mission

To inspire donor generosity and transform it into meaningful, lasting impact through charitable gifts.

Our Vision

To be the primary partner for donors who want to advance the community’s quality of life and capacity for excellence.

Bruce and Lynn Lindsey Skills Scholarship

Adults or graduating seniors from Lehman Catholic High School, Sidney Christian Academy, and Sidney High School who are enrolling in an accredited adult educational program or trade school or pursuing an Associate’s Degree.

Selection based upon (in order of priority):

• Demonstrated interest and passion for a specific career path, demonstrated work experience, demonstrated community or school service, and recommendations. Preference given to applicants seeking a career in HVAC, plumbing or electrical.

Awards

• Two $2,000 scholarships

Northern Chautauqua Community Foundation

Vision: We envision a vibrant, prosperous northern Chautauqua community, rich in opportunity today and tomorrow.

Our Mission

To realize our vision we focus on:

• strategic and responsive grant making
• encouraging local philanthropy and building permanent endowments for the future
• actively serving as a community leader and partner for the benefit and enrichment in our community.

Scholarships

Northern Chautauqua Community Foundation proudly manages over 200 individual scholarship funds,

Alice Reding Connell Nursing Scholarship

The Alice Reding Connell Nursing Scholarship is offered to graduating seniors in northern Chautauqua County who are pursuing a career in registered nursing.

William D. and Sallye T. Coleman Memorial Scholarship

This fund provides financial scholarships to deserving young men and women who attend public high school in Roanoke City and members of High Street Baptist Church.

Amount

Amount

• $ 1000+
• non-renewable

The Macy Faculty Scholars Program, funded by the Josiah Macy Jr. Foundation, supports early-career educators in medicine and nursing, promoting their development as future leaders. Scholars receive substantial financial support, mentorship, and access to educational resources, including funding for professional development activities and participation in a Harvard Macy Institute course. This initiative aims to enhance the educational landscape by nurturing diverse talent in the healthcare education field.

DeKalb County Farm Bureau Foundation

Mission – The Foundation’s mission is to broaden awareness and understanding of agriculture through outreach and education.

Scholarships

The DeKalb County Farm Bureau Foundation for Agriculture is proud to offer numerous scholarships for high school seniors and college students. Preference will be given to applicants of Farm Bureau members or their children with certain eligibility requirements.

College Students Scholarships 

The DeKalb County Farm Bureau Foundation endeavors to recognize students for their academic, school and community performance while in college. The recognition is in the form of a scholarship to the student’s school of choice. The scholarship award will be sent directly to the recipient’s school to be applied toward college costs. 

Russell & Berni Schelkopf Ag Scholarship

The Schelkopf family created this scholarship in 2022 to honor their parents, Russell and Berni, and their contributions to the agricultural industry. This scholarship is designed for a college student majoring in an ag-related field of study. One, $2,000 scholarship will be awarded annually to a sophomore, junior or senior in college.

DeKalb County Farm Bureau Foundation

Mission – The Foundation’s mission is to broaden awareness and understanding of agriculture through outreach and education.

Scholarships

The DeKalb County Farm Bureau Foundation for Agriculture is proud to offer numerous scholarships for high school seniors and college students. Preference will be given to applicants of Farm Bureau members or their children with certain eligibility requirements.

College Students Scholarships 

The DeKalb County Farm Bureau Foundation endeavors to recognize students for their academic, school and community performance while in college. The recognition is in the form of a scholarship to the student’s school of choice. The scholarship award will be sent directly to the recipient’s school to be applied toward college costs. 

Raymond & Frances Katz Ag Scholarship

Established in memory of Raymond & Frances Katz, this scholarship is open to students enrolled at the University of Illinois as an Agricultural and Consumer Economics (ACE) major (accounting, agribusiness, farm management, finance, consumer economics, environmental economics, or policy). One $2,000 scholarship will be given annually to a sophomore, junior or senior at Illinois.

DeKalb County Farm Bureau Foundation

Mission – The Foundation’s mission is to broaden awareness and understanding of agriculture through outreach and education.

Scholarships

The DeKalb County Farm Bureau Foundation for Agriculture is proud to offer numerous scholarships for high school seniors and college students. Preference will be given to applicants of Farm Bureau members or their children with certain eligibility requirements.

College Students Scholarships 

The DeKalb County Farm Bureau Foundation endeavors to recognize students for their academic, school and community performance while in college. The recognition is in the form of a scholarship to the student’s school of choice. The scholarship award will be sent directly to the recipient’s school to be applied toward college costs. 

Orville A. Olson Ag Scholarship

Established in memory of Orville A. Olson, this scholarship is available to college juniors and seniors majoring in an agriculture-related degree and seeking a career in a field of agriculture. One $1,200 ag scholarship will be awarded.

DeKalb County Farm Bureau Foundation

Mission – The Foundation’s mission is to broaden awareness and understanding of agriculture through outreach and education.

Scholarships

The DeKalb County Farm Bureau Foundation for Agriculture is proud to offer numerous scholarships for high school seniors and college students. Preference will be given to applicants of Farm Bureau members or their children with certain eligibility requirements.

College Students Scholarships 

The DeKalb County Farm Bureau Foundation endeavors to recognize students for their academic, school and community performance while in college. The recognition is in the form of a scholarship to the student’s school of choice. The scholarship award will be sent directly to the recipient’s school to be applied toward college costs. 

Leonard & Vivian Nelson Ag Scholarship

Family members established this scholarship in memory of Leonard and Vivian Nelson to benefit agricultural students. One $2,000 scholarship will be awarded to a student majoring in an agriculture-related field of study in their sophomore, junior or senior year of college.

DeKalb County Farm Bureau Foundation

Mission – The Foundation’s mission is to broaden awareness and understanding of agriculture through outreach and education.

Scholarships

The DeKalb County Farm Bureau Foundation for Agriculture is proud to offer numerous scholarships for high school seniors and college students. Preference will be given to applicants of Farm Bureau members or their children with certain eligibility requirements.

College Students Scholarships 

The DeKalb County Farm Bureau Foundation endeavors to recognize students for their academic, school and community performance while in college. The recognition is in the form of a scholarship to the student’s school of choice. The scholarship award will be sent directly to the recipient’s school to be applied toward college costs. 

DeKalb Ag Scholarship

The DeKalb Ag Scholarship was established in tribute to the DeKalb Ag company which originated in DeKalb, Illinois. Initial donations to this scholarship were provided by the DeKalb Ag Alumni Association and members. This $1,200 scholarship is for college students in their sophomore, junior, or senior year with an agriculture-related degree and eventually a career in agriculture.

The Professional & Technical Training Scholarships, offered by 10,000 Degrees, aim to support Marin County students facing financial challenges. These scholarships are designed for individuals enrolled in vocational programs that lead to a license or certificate. Eligibility includes being a Marin resident, attending an accredited institution, and having a GED or high school diploma. Preference is given to residents of Southern Marin, ensuring that local students receive the assistance they need to pursue their career goals.

Chautauqua Region Community Foundation

Mission: In partnership with our community, we ignite positive change and create a legacy of impact.

Scholarships

The Chautauqua Region Community Foundation annually awards more than $2 million in scholarships to students pursuing higher education, job training and certification. The Foundation hosts several different scholarship opportunities throughout the year. 

Music Scholarships

Open to Chautauqua County students (K-11) to assist with the cost of music instruction, or high school seniors and college students from Chautauqua County majoring in music. 

The Domestic Violence Prevention (DVP) grant from the IHS aims to enhance the capacity of Tribes and Urban Indian Organizations to combat domestic and sexual violence. This initiative promotes culturally appropriate, trauma-informed services, focusing on victim advocacy and collaboration across sectors. It addresses critical issues like human trafficking and child maltreatment, ensuring long-term sustainability through evidence-based practices and data sharing, ultimately improving community health and safety for AI/AN populations.

Community Foundation of Henderson County

Community Foundation of Henderson County was incorporated in 1982 by a group of fourteen dedicated and compassionate local leaders with the immediate need to manage two funds - the William C. Armstrong Scholarship Fund and the Charlie Renfrow Scholarship Fund, in addition to providing a permanent vehicle for citizens to give back to their community.

Our Mission is to help people who care make lasting contributions to causes that matter. The Community Foundation of Henderson County is a highly visible, philanthropic leader directed by an engaged and committed board, staffed by qualified employees, empowering donors at all levels to invest in professionally managed charitable funds that address community needs.

American Legion, Post 77, Hubert M. Smith Scholarship

The applicant must be the son, daughter, grandson, granddaughter or stepchild of a current member in good standing for 12 months prior to the scholarship deadline, or of a deceased member in good standing at the time of his death, of Hubert M. Smith, Post 77, American Legion. The applicant must be age 23 or less at the time of the application and be a graduating senior or graduate of a public, parochial or private school who intends to enroll in a two-year or four-year degree granting program.

The Canine Cancer Immunotherapy Network (K9CIN) aims to advance canine cancer treatments through innovative clinical trials, paralleling the development of human therapies. This initiative is vital as pet dogs naturally develop cancer, mirroring human responses to treatments. By leveraging NIH support, K9CIN will facilitate research to enhance immunotherapeutic strategies for both dogs and humans, fostering a collaborative environment for veterinary and human medical advancements. Ultimately, this funding opportunity promotes ethical research that benefits both species.

The Columbus Foundation

In 1943, during the darkness of World War II, a group of passionate citizens, led by Columbus businessman Harrison M. Sayre, envisioned a way to improve the well-being of the community and the quality of life in central Ohio. With little more than this sound idea and faith, The Columbus Foundation was established.

Our Mission

To assist donors and others in strengthening and improving our community for the benefit of all its residents.

McGuire-Holcomb Scholarship Fund

The scholarship was established in memory of the donor’s brother, William F. McGuire; mother, Ruth H. Holcomb; and stepfather Kenneth P. Holcomb. The scholarship provides tuition and books for the education of students who have a physical disability.

The OJJDP FY 2026 Missing and Exploited Children Training and Technical Assistance program aims to enhance the ability of state, Tribal, and local agencies to effectively address cases of missing and exploited children. This initiative will support multidisciplinary teams, including law enforcement and child protection personnel, to improve investigations and prosecutions. By providing essential resources and training, the program seeks to strengthen responses to protect vulnerable children and combat related public safety issues.

The Valley Foundation Grant aims to enhance the quality of life in Santa Clara County and beyond by supporting qualified 501(c)(3) organizations. Focused on educational, historical, and preservation initiatives, the Foundation provides essential funding to groups dedicated to societal improvement. By fostering partnerships with like-minded entities, The Valley Foundation strives to create lasting positive change through its grant-making efforts.