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Find the perfect Operating grants for nonprofits in South Dakota on Instrumentl. 9,000+ Operating grants for nonprofits in South Dakota in the United States.
9,000+
Available grants
$2.62B
Total funding
$5K
Median grant
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About Patient Advocate Foundation
Patient Advocate Foundation is the nation’s most comprehensive nonprofit dedicated to helping patients navigate, access, and afford the care they need—while improving the healthcare system for all.
Who we are and our impact
Patient Advocate Foundation provides financial assistance to help patients afford treatment and cost of living needs, personalized case management to navigate complex healthcare and social needs challenges, and a wide array of resources to empower people to take charge of their health. Since our founding in 1996—and joining forces with the PAN Foundation in 2026—we have helped 3.8 million patients navigate and access care, granted over $7 billion in financial assistance, served 350,000 people through personalized case management and elevated the patient’s voice to drive improvements in the healthcare system.
Paroxysmal Nocturnal Hemoglobinuria (PNH)
Help with healthcare costs for Paroxysmal Nocturnal Hemoglobinuria (PNH)
This TotalAssist fund helps you pay for out-of-pocket healthcare costs, including medication copays, coinsurance, and deductibles, health insurance premiums, and other expenses.
About the disease
Paroxysmal Nocturnal Hemoglobinuria (PNH), also known as Marchiafava– Micheli syndrome, is a rare disease that is characterized by impaired bone marrow function and destruction of red blood cells. PNH is a rare disease that affects the circulatory system.
Mission
To empower worthy nonprofits by providing critically needed, unrestricted funding that helps them fulfill their missions with confidence and sustainability.
How We Serve Nonprofits
AmFund partners with nearly 800 organizations annually—supporting causes related to health, education, the arts, human services, animal welfare, and more. We’re known for our:
Request Support
Our model is built on relationship, trust, and results. Every trip sold, every service provided, and every donor interaction is designed to maximize your fundraising impact—without adding burden to your team.
Danny Did Foundation
The Danny Did Foundation is a not-for-profit corporation organized in the state of Illinois and recognized by the Internal Revenue Service as a 501©(3) tax-exempt organization.
Founded by Chicagoans Mike and Mariann Stanton in January 2010 after the death of their four-year-old son Danny, the Danny Did Foundation works toward its mission to prevent deaths caused by seizures with these main goals in mind: advancing public awareness of Sudden Unexpected Death in Epilepsy (SUDEP), enhancing SUDEP education and disclosure between medical professionals and families afflicted by seizures, and the mainstreaming of seizure detection and prediction devices that may assist in preventing seizure-related deaths.
Danny Did Foundation Reimbursement Grant
The Danny Did Foundation (“Foundation”) strives to assist individuals and families living with seizures. With an approved Request for Funding, the Foundation will provide monetary funding to the Grantee so they may gain access to a particular device or technology (“Device”) that the Grantee, in collaboration with the Grantee’s medical providers and professionals, independently deem appropriate. This money shall be defined as “Funds” and the spending of any Funds shall be at the sole discretion of the Grantee. The Foundation does not direct, limit, participate, or manage the decision-making or purchase of any specific Device.
While no Device has been proven to prevent epilepsy-related mortality (including SUDEP), the Danny Did Foundation is devoted to seeking out resources that may assist families living with epilepsy.
Reimbursement Grant: Danny Did will consider partial reimbursement for device purchases made in the last 30 days. I have already purchased the epilepsy device. I am seeking reimbursement and will provide receipt of purchase to the Danny Did Foundation to be considered for funding.
Powering Economic Opportunity Fund
Converting America's economic transformation into lasting earnings gains for workers — by backing the employer-side job designs and workplace practices that a durable payer will carry forward.
Across the United States, the modernization of energy systems, physical infrastructure, and advanced manufacturing is creating sustained demand for skilled workers — electricians, welders, energy technicians, construction managers, and industrial specialists — even as the broader labor market has slowed. The Bureau of Labor Statistics projects that energy-related occupations will be among the fastest-growing through 2034, and critical trades face significant shortages as experienced workers retire.
Geopolitical uncertainty and conflicts only accelerate these trends and the need to focus on energy security. At the same time, AI-driven disruption continues to displace entry-level knowledge roles, creating a strong and underserved candidate pool for durable trade pathways.
Investments are expanding access to skilled trades training, but a critical gap remains between funding workforce programs and achieving lasting employment outcomes. Too many workers complete training without staying in quality jobs, and too few investments address the employer practices that improve retention, advancement and long-term earnings.
As part of our multiyear partnership with Families and Workers Fund, GitLab Foundation is pleased to announce a $4M open call for the Powering Economic Opportunity Fund — flexible grants of up to $500,000 supporting organizations that partner directly with employers, unions and industry to strengthen work-based learning, improve job quality and connect workers to durable, living-wage careers. Round 2 invests in employer-side practice change — the job designs and workplace practices that help workers stay, advance, and build careers — and in the durable financing that sustains those practices after the grant ends.
Our Mission
The Sundance Institute is a nonprofit organization dedicated to the discovery and development of independent artists and audiences. Through its programs, the Institute seeks to discover, support, and inspire independent film and media artists from the United States and around the world, and to introduce audiences to their new work.
Sally Menke Editing Fellowship
Description of Fellowship
The Sally Menke Editing Fellowship will include the following elements:
Danny Did Foundation
The Danny Did Foundation is a not-for-profit corporation organized in the state of Illinois and recognized by the Internal Revenue Service as a 501©(3) tax-exempt organization.
Founded by Chicagoans Mike and Mariann Stanton in January 2010 after the death of their four-year-old son Danny, the Danny Did Foundation works toward its mission to prevent deaths caused by seizures with these main goals in mind: advancing public awareness of Sudden Unexpected Death in Epilepsy (SUDEP), enhancing SUDEP education and disclosure between medical professionals and families afflicted by seizures, and the mainstreaming of seizure detection and prediction devices that may assist in preventing seizure-related deaths.
Danny Did Foundation Hardship Grant
The Danny Did Foundation (“Foundation”) strives to assist individuals and families living with seizures. With an approved Request for Funding, the Foundation will provide monetary funding to the Grantee so they may gain access to a particular device or technology (“Device”) that the Grantee, in collaboration with the Grantee’s medical providers and professionals, independently deem appropriate. This money shall be defined as “Funds” and the spending of any Funds shall be at the sole discretion of the Grantee. The Foundation does not direct, limit, participate, or manage the decision-making or purchase of any specific Device.
While no Device has been proven to prevent epilepsy-related mortality (including SUDEP), the Danny Did Foundation is devoted to seeking out resources that may assist families living with epilepsy.
Hardship Grant: I am unable to make a purchase for the epilepsy related resource I seek therefore I am requesting a hardship grant. If I am approved for funding, I agree to provide a receipt for the resource I purchase to the Danny Did Foundation within 14 days of receiving the grant check, or I will return the funds to the Danny Did Foundation.
About Us
The Soil and Water Conservation Society (SWCS) is the premier international organization for professionals who practice and advance the science and art of natural resource conservation.
SWCS Emerging Leaders Program Alumni Award
The Emerging Leader Alumni Award recognizes outstanding alumni of the Emerging Leaders Program (ELP) who have demonstrated a commitment to conservation leadership and active participation in the Soil and Water Conservation Society (SWCS). Three $500 cash awards will be granted to support professional development, Society membership, conference fees, or other career-enhancing opportunities.
About Us
We are YOUR Community Foundation! Our mission is to bring people and resources together to strengthen the quality of life, both now and in the future, for the residents of Randolph County.
The Community Foundation of Randolph County, Inc. is here to make our community the very best place to live, work, and raise a family. As a non-political private organization, we are uniquely able to provide grant money for innovative projects that have a major impact on our community.
Donald Forrest Hahn & Wilma Fraley Hahn Memorial Scholarship Fund
Donald Forrest Hahn and Wilma (Fraley) Hahn were high school sweethearts in Hollandsburg, Ohio where they graduated in 1941. Don enrolled at Earlham College, but was drafted into the Army to serve in World War II. He was part of the 3rd Army under the command of General Patton and his unit fought at Normandy Beach on D-Day, in the Battle of the Bulge, and in the battle for the Remagen Bridge. Don received a Silver Star, two Bronze Stars, one with clusters and a purple heart for shrapnel wounds. Don was a member of the Honor Guard for General Patton’s funeral. Wilma obtained her nursing degree from Reid Memorial Hospital. When Don returned from the war in 1946, they married and moved to 298 No. Jackson Street in Winchester where they lived as man and wife for 70 years in that same house. Don passed away on December 24, 2016 and just 30 hours later Wilma died on December 25. Wilma worked as an emergency room nurse from 1946-1949 and then was employed by the Randolph County Hospital from 1950-1968. From 1968 until her retirement in 1986 Wilma was Randolph Central School corporation’s nurse. Don farmed, was a rural route mail carrier, a member of the Lion’s Club and served on the school board for the Randolph Central School Corporation. He was on the board when the new high school was built. Don and Wilma were members of the First United Methodist Church of Winchester for 70 years. Both Don and Wilma were awarded Sagamores of the Wabash. They had three children, Greg, Randy and LeighAnne. Both Don and Wilma valued public school education and held higher education as a priority.
Awarded to a Randolph County, Indiana High School graduate with a financial need. Preference to be given to a student(s) pursuing a degree in Agriculture or Nursing.
About Scholarships
Through the incredible generosity of our donors, the Community Foundation of South Puget Sound manages 26 scholarship funds that offer a wide range of scholarship awards and encourage students of all backgrounds and educational interests to apply. We also want to extend a sincere thank you to our many scholarship donors, advisors, and scholarship committee members for their investment in our student's bright futures this year and for many years to come!
Learning Seed Foundation Scholarship
The Learning Seed Foundation Scholarship Fund was established by the Learning Seed Foundation to assist graduating high school seniors in Thurston and Pierce counties in obtaining a higher education. This scholarship is designed to benefit primarily students of color who have overcome significant obstacles and demonstrate a commitment to others. The scholarship has the potential to be renewed for up to an additional 3 years of undergraduate education. Reapplication each year is required.
Syndax Pharmaceuticals, Inc.
At Syndax, we are determined to realize a future in which people with cancer live longer and better than ever before. We believe that it takes a community to build a great medicine, and that is why we are working to set the new standard for developing medicines in the field of oncology – one that revolves around collaboration, shared learning, and excellence.
Syndax’s mission is to obtain regulatory approval and commercialize drugs that extend and improve the lives of cancer patients by drawing on the newest scientific research and advances, collaborating with determined problem solvers, and identifying value in overlooked aspects of science.
Educational Funding
At Syndax, we are committed to the goal of supporting objective, balanced and scientifically rigorous education that furthers improvements in science, medicine, and patient care. We accomplish this goal, in part, by providing grants for independent medical education (IME) programs. These can include live, online, and/or enduring programs that educate healthcare providers (HCPs), patients, or caregivers. Programs that are funded via Syndax medical education grants must be primarily dedicated, in both effort and time, to medical, health or scientific topics that are objective, balanced, unbiased, and scientifically rigorous. Medical education grants must never be made with the intent to directly or indirectly reward, influence or encourage the recipient to prescribe, purchase, sell or arrange for any Syndax product.
Looking for operating grants for nonprofits in South Dakota?
Read more about each grant below or start your 14-day free trial to see all operating grants for nonprofits in South Dakota recommended for your specific programs.
How common are grants in this category?
Uncommon — grants in this category are less prevalent than in others.
Over the past year, when are grant deadlines typically due for Operating grants for Nonprofits in South Dakota?
Most grants are due in the first quarter.
What's the typical grant amount funded for Operating Grants for Nonprofits in South Dakota?
Grants are most commonly $10,000.
What's the typical amount funded for South Dakota?
Grants are most commonly $110,621.
What's the total number of grants in Operating Grants for Nonprofits in South Dakota year over year?
In 2024, funders in South Dakota awarded a total of 6,460 grants.
Among all the Operating Grants for Nonprofits in South Dakota given out in South Dakota, the most popular focus areas that receive funding are Education, Human Services, and Philanthropy, Voluntarism & Grantmaking Foundations.
1. Education
2. Human Services
3. Philanthropy, Voluntarism & Grantmaking Foundations
How is funding for Operating Grants for Nonprofits in South Dakota changing over time?
Funding has increased by 17.48%.
How does grant funding vary by county?
Minnehaha County, Lake County, and Pennington County receive the most funding.
| County | Total Grant Funding in 2024 |
|---|---|
| Minnehaha County | $176,653,145 |
| Lake County | $117,647,066 |
| Pennington County | $90,630,616 |
| Brookings County | $75,457,854 |
| Todd County | $56,559,538 |