Best Operating Grants for Nonprofits in South Dakota

The Genesis Mission Graduate Fellowship Pilot aims to empower American scientists and engineers in the super intelligence (SI) revolution by inviting applications from U.S. higher education institutions. This initiative focuses on developing innovative doctoral training programs integrating SI with other scientific disciplines. Participants will gain valuable research experience through collaborations with DOE National Laboratories and industry, preparing them as the next generation of skilled Ph.D. scientists and engineers to tackle pressing national science and technology challenges.

Confederated Tribes of Siletz Indians

The Confederated Tribes of Siletz Indians is a sovereign nation and has three main branches of government – Judicial, Executive, and Legislative. One of our most important resources is our people.

Education

The Confederated Tribes of Siletz seeks to provide opportunities for Tribal members to reach potential, establish independence and improve quality of life through lifelong learning and education.

Cathern Tufts Memorial Scholarship

Cathern Tufts, affectionately known as “Cat” in the offices of the CTSI administrative offices and Tribal elder woodcuts, was the Tribal Attorney for fourteen and a half years until she passed in 2018 following a short illness. She was a Siletz Tribal member who graduated from Arizona State University School of Law. She served an internship in Washington D.C. prior to going to work as an attorney. Her parents and friends wished to honor her life and achievements through this memorial scholarship. This scholarship is for students in pre-law, law, or in a natural resource field.

The AAAE Diversity, Equity & Inclusion Scholarship, provided by the AAAE Foundation, supports ethnic diversity students pursuing aviation studies in the U.S. or Canada. With two awards of $5,000 each, recipients are chosen based on their academic achievements, financial need, and community involvement. Eligible applicants include college juniors, seniors, or graduate students with a minimum GPA of 3.0. This scholarship aims to foster future leaders in the aviation industry, enhancing diversity and inclusion.

Don and Bern Holcomb Memorial Scholarship

This scholarship was created in memory of Don and Bern Holcomb and is for high school students from any school in Cattaraugus or Allegany county who plans to attend an accredited post-secondary institution, with a preference for a student majoring in an agricultural or conservation-related field or a female pursuing an engineering degree.

The Tribal Institutional Review Board Establishment and Enhancement (TIRBEE) award aims to assist federally recognized AI/AN Tribes, Tribal colleges and universities, and Tribal health organizations in creating or enhancing Institutional Review Boards (IRBs). This initiative is crucial for ensuring ethical research practices within Tribal communities, fostering cultural sensitivity in research, and protecting the rights of AI/AN participants. Applications must be submitted by 5:00 PM local time of the applicant organization.

The Alfred P. Sloan Foundation Research Fellowship supports innovative and fundamental research by early-career scientists across various fields. This prestigious two-year fellowship offers $75,000 in a lump sum, allowing recipients to allocate funds towards research-related expenses. Eligible candidates must hold a Ph.D. and be tenure-track faculty at U.S. or Canadian institutions. The fellowship aims to nurture the next generation of leaders in research and academia.

The Mercer Vu Farms/Ron and Judy Hissong Scholarship for Agriculture Fund honors Ron Hissong, a dedicated dairy farmer. Established by his family, this scholarship supports students from the Tuscarora School District pursuing education in agriculture or related fields, ensuring they can continue Ron's legacy of community contribution. Applicants must demonstrate financial need and a commitment to agriculture, making this opportunity vital for aspiring agricultural professionals.

The Master's Degree Scholarship Program for Under-Represented Minority Students, offered by the Environmental Engineering and Science Foundation, provides three scholarships of $2,500 each. These scholarships aim to support students from diverse backgrounds who are pursuing a Master's Degree in Environmental Engineering or a related field. Applicants must demonstrate academic excellence with a minimum GPA of 3.0 and must identify as part of specific under-represented groups.

The Stanford Children's Health Center for IBD and Celiac Disease offers Intramural Seed Grants to promote innovative research in pediatric diseases. This program supports high-risk, high-reward projects, encouraging multi-PI collaborations across disciplines. Awards of up to $100,000 per year for two years are available, aimed at generating preliminary data for future funding applications. Eligible applicants include Stanford faculty holding specific university positions. Proposals should focus on advancing understanding of pediatric IBD and celiac disease through various research approaches.

The HEAL Initiative aims to address the significant overlap between chronic pain (CP) and opioid use disorder (OUD), with 40-75% of individuals affected by both. The IMPOWR project focuses on testing innovative interventions and implementation strategies to integrate care for CP and OUD across various health systems. The BEACON Center will enhance network coordination, build capacity, and develop resources to address barriers in service delivery, ultimately improving sustainability and scalability of evidence-based practices.

Patagonia supports environmental organisations with bold, direct-action agendas and a commitment to long-term change.

We support innovative work that addresses the root causes of the environmental crisis and seeks to protect both the environment and affected communities. We focus on places where we’ve built connections through outdoor recreation and through our network of retail stores, nationally and internationally.

We believe local battles to protect a specific stand of forest, a stretch of river, an indigenous wild species or a community from a polluting refinery build public support and confront larger, more complex issues like climate change, biodiversity loss and environmental justice.

We encourage work that brings underrepresented communities to the forefront of the environmental movement and defends communities whose health and livelihoods are threatened by environmental exploitation.

We support multipronged campaigns that push for greater environmental protections and force the government to abide by its own laws.

We fund work that:

• builds an equitable, inclusive and diverse environmental movement
• confronts systemic bias, discrimination and injustice in environmental policy or outdoor spaces
• is action-oriented
• focuses on root causes
• has a clear strategy
• identifies specific goals and objectives that can be effectively measured to evaluate success
• builds public involvement and civic engagement

Patagonia believes that the most direct path to real change is through building grassroots momentum.

Our funding focuses on organisations that have or can create a strong base of support. Because we’re a privately held company, we have the freedom to fund risk-taking, off-the-beaten-track groups, and that’s where we believe our small grants are most effective.

The Stanford Medicine Children’s Health Center for IBD and Celiac Disease offers funding for postdoctoral fellows and instructors to conduct innovative research focused on pediatric IBD and celiac disease. This initiative aims to nurture future researchers and prepare them for independent funding opportunities. Eligible research includes basic, clinical, epidemiological, and health policy studies related to maternal and child health. Funding supports substantial salary and benefits, ensuring commitment to impactful research in this critical area.

The Teresa and David R. Schmidt, M.D. Scholarship Fund, managed by the San Antonio Area Foundation, supports high school seniors pursuing careers in the medical field. Eligible applicants must demonstrate financial need and maintain full-time enrollment at accredited institutions. This renewable scholarship assists with tuition, fees, and books for students from specific Texas counties, fostering community growth and educational opportunities in healthcare since 1964.

The Environmental Engineering and Science Foundation offers six Master's Degree scholarships of $2,500 each for students pursuing advanced studies in Environmental Engineering or related fields. Eligible candidates must be U.S. citizens or permanent residents, have a strong academic record with a minimum GPA of 3.0, and be accepted into an accredited graduate program. This initiative aims to support future leaders in environmental engineering and science.

The Ruth Goldstein Memorial Music Scholarship supports graduating seniors from Capital Region high schools who plan to pursue music education or performance. Offered by The Community Foundation for the Greater Capital Region, this scholarship prioritizes students specializing in woodwind instruments, piano accompaniment, or those demonstrating financial need. Since 1968, the foundation has empowered the community through generous giving opportunities, enhancing the quality of life for all residents.

The Periodic Paralysis Grant, offered by the Patient Advocate Foundation, assists individuals diagnosed with periodic paralysis in managing out-of-pocket healthcare costs. Eligible applicants must be in treatment or planning to begin treatment for this rare muscle disease. The fund covers various expenses, including medication copays and insurance premiums, ensuring that patients can afford essential care. With a mission to empower and support patients, this grant plays a crucial role in navigating healthcare challenges.

The BIE Professional Examination Funding, provided by Native Forward Scholars Fund in partnership with BIE, offers financial assistance to support Native students in taking professional examinations, including Bar Examination funding. This award covers registration fees, preparatory course costs, and other exam-related expenses. Applicants must have graduated within one year and can only receive assistance for one exam. This initiative aims to empower Native scholars and enhance their professional visibility and opportunities.

The Dr. Chao-ying & Sue Wu Early Learning Scholarship, established by the Chuckanut Health Foundation in 2022, honors the vital contributions of Dr. Chao-ying and Sue Wu to the health and education of Whatcom youth. This scholarship aims to eliminate financial barriers for local students pursuing careers in early learning, reflecting the Foundation's commitment to investing in community potential and fostering opportunities for future generations.

The Hypercholesterolemia Grant by the Patient Advocate Foundation offers financial assistance to individuals diagnosed with hypercholesterolemia, helping cover out-of-pocket healthcare costs such as medication copays and insurance premiums. This nonprofit aims to improve patient access to necessary care while supporting over 3.8 million patients since its inception. Eligible applicants must have health insurance and meet specific income requirements to receive assistance in managing their healthcare expenses effectively.

The Robert B. Taylor Fund, managed by the San Antonio Area Foundation, supports students pursuing higher education in vocational fields or those seeking associate degrees. Available to high school seniors, college students, and adult learners, it emphasizes financial need and academic performance, specifically a minimum GPA of 2.5. Preference is given to Black or African American students and those enrolled in Alamo Community Colleges. This fund aims to enhance educational opportunities and community growth.

The Native Forward Community Impact Research Funding supports doctoral candidates conducting research that addresses issues affecting Indian Country. This initiative provides essential financial assistance for data collection, analysis, and research travel, ensuring that Native perspectives are included in academic discourse. By fostering the next generation of Native leaders, this funding aims to empower scholars and enhance community impact through education and advocacy, ultimately preserving and enriching Native cultures.

The NRF Foundation Retail Management Scholarship, in partnership with CVS Health, is designed to inspire undergraduate students to pursue careers in retail leadership. Eligible candidates can receive a $10,000 scholarship and attend the NRF Foundation Student Program in NYC in January 2026. This program provides networking opportunities with top retail executives and recruiters, along with insights into career pathways in the retail industry, making it a valuable experience for aspiring leaders.

The Public Health Nursing initiative aims to enhance the health and wellness of American Indian and Alaska Native men by implementing a culturally sensitive case management model. Through this program, Public Health Nurses will provide preventive health services, facilitate access to care, and encourage healthy lifestyle choices. By promoting early identification and management of health issues, the initiative strives to improve overall community health outcomes through targeted, collaborative interventions.

The DHQP Global NOFO aims to enhance the CDC's mission against antimicrobial resistance (AR) by integrating non-research implementation with focused research. This initiative addresses urgent global threats posed by various pathogens and healthcare-associated infections (HAIs). By leveraging existing CDC networks, the NOFO seeks to improve detection, surveillance, and infection control measures, ultimately reducing illness and mortality while protecting healthcare workers and patients, especially in low and middle-income countries.

Community Foundation of the Fox River Valley

The Community Foundation of the Fox River Valley is a collection of individual funds and resources given by local citizens to enhance and support the quality of life in the Fox River Valley of Illinois.

We are a tax-exempt public charity that allows individuals, businesses, and non-profit organizations to establish permanent endowments and temporary funds within the confines of one large foundation.

Foundation funds are used to provide grants to non-profit organizations and scholarships to area students. The Foundation also hosts a Youth Engagement in Philanthropy (YEP) program, which helps high school students learn more about philanthropy and empowers them to make a difference in the community.

The Community Foundation of the Fox River Valley serves the City of Aurora, Kane County, and Kendall County within the State of Illinois.

Robert J. O’Connor Memorial Scholarship Fund

The Robert J. O’Connor Memorial Scholarship Fund was created as a way to honor his long-standing relationship with the Community Foundation and the passion he held for helping local students pursue their educational goals. Bob’s connection to the Community Foundation started when he was the recipient of a scholarship as a 1962 graduate of East Aurora High School. He would later serve nine years as a Foundation Board member.

The Hyperkalemia Grant, provided by the Patient Advocate Foundation, offers crucial financial assistance to patients struggling with hyperkalemia. This grant covers out-of-pocket healthcare costs, including medication copays and health insurance premiums. Eligible applicants must have a confirmed diagnosis and meet specific income and residency requirements. Since its inception, the foundation has supported millions of patients, ensuring they can access the necessary treatment and resources for their health needs.

The Louis Stokes Alliances for Minority Participation (LSAMP) Bridge to Doctorate Scholars Program, funded by the National Science Foundation, aims to recruit and retain minority graduate students in STEM fields. This program offers significant benefits, including a $32,000 annual stipend and $12,000 educational allowance for two years, fostering a supportive community through monthly dinners for Indigenous graduate students. Eligible applicants must be U.S. citizens, identify as American Indian or Alaska Native, and have participated in an LSAMP program.