Best Seed Grants for Nonprofits in South Dakota

The ROSES 2025: D.4 program by NASA focuses on enhancing theoretical and computational astrophysics through collaborative networks. It aims to address grand challenges in Time Domain Multi-Messenger Astrophysics by integrating diverse expertise from various fields. Researchers from U.S. institutions are encouraged to propose innovative tools for modeling complex multi-messenger phenomena, fostering interdisciplinary collaboration across academic, national laboratory, and private sectors to prepare the next generation of scientists.

The NIH Mentored Research Scientist Development Award (K01) supports early-career scientists with up to five years of protected time for intensive research training in biomedical, behavioral, or clinical sciences. This award is tailored for those pursuing independence in research and is particularly beneficial for individuals transitioning fields or returning from a hiatus. Importantly, applicants must not lead independent clinical trials but may participate in trials overseen by mentors.

The Science Ambassador Scholarship, funded by Cards Against Humanity, offers full tuition for women and non-binary students pursuing degrees in STEM fields. This scholarship is open to undergraduate students and high school seniors, regardless of U.S. citizenship, as long as they plan to attend college in the United States or its territories. Eligible applicants must major in science, technology, engineering, or math.

The EA Infrastructure Fund Grant supports projects that enhance effective altruism by improving access to talent, capital, and knowledge. With grants typically ranging from $5,000 to $200,000, it welcomes applications from individuals, nonprofits, and academic institutions worldwide. However, individuals must ensure their projects conclude by August 31, 2025. The fund aims to amplify the impact of direct charitable work and foster a community committed to effective altruism principles.

The NIH Mentored Research Scientist Development Award (K01) aims to support emerging scientists by providing protected time for career development in biomedical, behavioral, or clinical sciences. This award, effective for three to five years, encourages research independence and may be beneficial for those transitioning fields or returning from a hiatus due to personal circumstances. Deadlines for applications vary, with important dates set for standard, renewal, and AIDS-related submissions.

The Procter & Gamble Strategic Fund Grant aims to enhance lives through impactful initiatives such as infant development, hygiene, and oral care. As a highly competitive fund, it supports IRS-designated 501(c)(3) organizations that provide national programs where P&G can uniquely add value. Interested applicants should carefully assess their eligibility and align with the grant's specific focus areas before applying.

The ISF Public Interest Legal Fellowship empowers American Muslims by providing opportunities in public interest law. This fellowship offers a salary of $70,000, professional development workshops, and mentorship to help fellows advance their careers. Applicants must be active members of the Muslim community, have graduated from law school within the last three years, and have secured a host organization for their project proposal. This initiative aims to increase representation and influence in policy-making.

 Parkston Area Foundation 

The Parkston Area Foundation (PAF) is a tax-exempt organization developed in 2004. Our mission is to promote philanthropy and support a wide range of social, economic, and charitable needs in the greater Parkston area.

The purpose of the PAF Board is to raise funds to create a community savings account which will grow and benefit the communities of Dimock, Milltown, Hillside, and Parkston. The funds are deposited with the South Dakota Community Foundation which invests the dollars and annually returns earned interest to the PAF for grant distributions. The Parkston Area Foundation has been annually awarding grants to support the community since 2007.

Grants

Since 2007, the Parkston Area Foundation has combined efforts with the Opie R. Benson and Helen A. Benson Community Improvement Foundation as well as the Avera St. Benedict Foundation in awarding grants every year. In 2007, the three foundations pooled monies and granted a total of $10,000 in funds. Since 2008, the foundations have continued to work together giving out grants each year, but have since each designated specific amounts to recipients.

Parkston Area Foundation Grant

Qualification

Purpose of the project should fulfill a community need and should involve a tangible and measurable means of evaluation.

Volunteerism

Projects that involve significant and continuous community volunteer support will be favorably considered.

Innovation

The Parkston Area Foundation (PAF) funds ongoing, well-established projects as well as innovative projects designed to address existing community needs in innovative ways.

Discrimination

Applications from persons and/or agencies offering services exclusively to one gender, age group, or race will be closely scrutinized for discriminatory practices. Funding will be based on the needs of the individuals being served.

Continued Funding

No guarantee of continued funding will be communicated until subsequent grant applications are reviewed. However, once initiated under foundation funding, projects with a good track record will be considered favorably in subsequent grant decisions. No more than three years of sequential grant funding shall be awarded to any one grantee for the same purpose.

Challenge Grants

The PAF encourages matching funds from all grant applicants. When the board perceives the need for more local involvement and support of a given project, it may issue challenge grants in any proportion. Funding may be contingent upon acquisition of the required matching money. There may be times when the PAF perceives a need in the community currently not being met. The board then may issue a challenge grant to the community or request a proposal to address that particular need.

The Sharing Language Diversity Fellowship supports Ph.D. students engaged in Indigenous language documentation and data archiving. Funded by the Endangered Language Fund, it encourages sustainable public sharing of linguistic materials, aiming for equitable access to research. With grants up to $30,000, recipients must publicly archive documentation materials within three years, ensuring compliance with community wishes and best practices. This initiative fosters a culture of Open Access in linguistics, benefiting both scholars and Indigenous communities.

The Lenora Jane Perdue Scholarship, offered by the North East Community Foundation, supports graduating seniors from Westfield Academy, Ripley Central School, and North East High School pursuing a degree in education. Applicants must maintain a GPA of 3.0 or higher. This scholarship aims to encourage and assist students dedicated to a career in teaching, fostering the next generation of educators in their community.

Committee of 100 Academic Scholarship

Awards:

• One time award of $5,000.

Self-Defense Grants for MMIR Day

Facilitators, educators, organizers — May 5th is the Day of Awareness for Missing & Murdered Indigenous Women, Girls and Relatives. In honor of that day, we are offering mini grants to host a self-defense workshop for Indigenous girls and gender-expansive youth.

Why self-defense?

• Native women are murdered at 10x the national rate
• 84% experience violence in their lifetime
• Over 5,700 Native girls go missing each year

We also name the invisible crisis:

• Indigenous people from Mexico & Central America (Maya, Nahua, Zapotec, Mixtec, Lenca, and others) living in the U.S. face detention, deportation, and disappearances that are rarely counted in MMIR data.
• When a Tzotzil 18 year old like Royer Perez Jimenez dies in ICE custody, the silence is deafening.

Self-defense must include all Indigenous relatives.

XCNC has:

• $500 mini grants for stipends, space, supplies, and translation.

What we ask:

• Plan a workshop between May 5–31, 2026, rooted in community care.

The Kazanjian Economics Foundation Grant focuses on enhancing economic literacy across various educational settings. With a history of over 70 years, the foundation supports projects that deliver economic education to youth, particularly in non-school environments. It emphasizes teacher training and initiatives for underserved communities, while also promoting behavioral economics and entrepreneurship. The foundation welcomes letters of interest year-round, with recommended deadlines of March 10th and September 10th for grant cycles.

The Community Foundation of Shelby County

Our Mission

To inspire donor generosity and transform it into meaningful, lasting impact through charitable gifts.

Our Vision

To be the primary partner for donors who want to advance the community’s quality of life and capacity for excellence.

Ginny and Jim Thompson Scholarship

Selection based upon (in order of priority):

Financial need, academic ability, recommendations, and an essay, “Why is education important to me?”

Awards

• One $1,000 scholarship

Investing in research and healthcare to prevent, treat, and heal firearm-related harms

Kaiser Permanente Center for Gun Violence Research and Education

Kaiser Permanente established this Center in 2022 to scale its longstanding commitment to help communities prevent, treat, and heal from firearm-related injuries or death. The Center’s focus on violence prevention is rooted in healthcare, care delivery, and clinical interventions.

The Center is coordinated in collaboration with the Health Alliance for Violence Intervention (HAVI).

Research to support more effective health interventions

The Center funds research to test and expand health interventions that treat and prevent firearm injuries and deaths. This approach uses the same rigor and expertise that has helped treat and prevent other leading health concerns and causes of death, such as stroke, cancer, and heart disease. Funding supports projects to:

• Identify and evaluate health system strategies to address firearm injury and death, especially in communities that are most impacted.
• Test clinical interventions to prevent, treat, and heal trauma caused by firearm injuries and death.
• Assess pathways to implement and scale clinical interventions for firearm injury prevention in various healthcare settings.
• Improve healthcare identification and engagement of individuals at high risk of firearm injury or death.

Since its inception, the Center has awarded more than $8.5 million through 49 grants across 25 states and Washington, D.C., to advance research, capacity building, narrative change, and education.

Funding Opportunity

The call is open to applicants at varying stages of the research continuum. It is expected that central to all proposed initiatives are efforts to meaningfully engage communities that have been the most impacted by firearm violence.

What Work Will Be Considered for Funding?

Funding is currently available in two categories: Category 1 - Research Capacity Building; Category 2 - Pilot or Formative Healthcare Research

Category 1: Research Capacity Building

Up to two (2) projects will be selected, each receiving up to $100,000 over two (2) years.

Build capacity within the organization, institution, and/or clinical care setting to conduct research on healthcare approaches to addressing firearm violence or firearm suicide.

American Physical Society

The American Physical Society is a nonprofit membership organization working to advance physics by fostering a vibrant, inclusive, and global community dedicated to science and society. APS represents more than 50,000 members, including physicists in academia, national laboratories, and industry in the United States and around the world.

APS Honors recognizes and celebrates the accomplishments of the global physics community. Guided by our core values, APS Honors encourages nominations that reflect the full range of talent, distinction, and experience in our field, and supports broad canvassing for professional achievement across diverse backgrounds, perspectives, and expertise.

Joseph A. Burton Forum Award

The Joseph A. Burton Forum Award recognizes outstanding contributions to the public understanding or resolution of issues involving the interface of physics and society. The award consists of $5,000, a certificate citing the contributions of the recipient, and an allowance for travel to the meeting of the Society at which the award is presented. It will be awarded annually.

Nominations will be considered for three review cycles provided the nominator re-certifies the nomination before the next deadline.

About Spirit of Blue

Our Vision

To become the nation’s leading supplemental provider of law enforcement safety equipment and training across the county.

Our Mission

Spirit of Blue is dedicated to the enhancement of officer safety throughout the law enforcement community by fulfilling unfunded safety equipment and training needs.

Safety Grant Program

Spirit of Blue’s primary initiative is the granting of safety equipment and training to municipal, county and state law enforcement agencies in an effort to protect their sworn personnel. 

Most grants are 100% funded, meaning that no match is required. In the majority of cases, Spirit of Blue conducts the procurement of the goods or services being granted so that the recipient agency isn’t burdened with having to negotiate prices, place orders or track delivery. Rarely, if ever, does Spirit of Blue provide cash awards. Once selected, Spirit of Blue will provide the recipient agency with an official grant award letter outlining everything that is contained in the award. The recipient agency must gain acceptance of the grant, whether on the authority of their agency head or by working with their local governing authority as their policy may dictate. There are no reporting requirements after the award of the grant, but agencies are asked to submit a photo to be used in the announcement of their grant.

Grant Application

The Spirit of Blue Safety Grant Program is designed to award equipment, or in some cases training, that will protect officers serving on duty. You should only request items that you can articulate will have a positive impact on officer safety.

The Chan Zuckerberg Initiative is calling for transformative research proposals through the Advancing Technologies for Spatiotemporal Omics in Live Tissue program. This initiative seeks to combine innovative engineering with biological research to explore the complex molecular dynamics of health and disease. By fostering collaboration among scientists and AI experts, this funding aims to unlock new high-precision interventions, significantly advancing our understanding and management of health issues.

The Radiation Exposure Screening and Education Program aims to support organizations in their efforts to screen and educate individuals who have been exposed to radiation from uranium mining and U.S. nuclear weapons testing. This initiative emphasizes the importance of awareness and education in mitigating health risks associated with radiation exposure, ensuring affected communities receive the necessary resources and support for health management.

The Capacity Accelerator for Tribal Offshore Wind Engagement, launched by the U.S. Department of Energy, aims to empower Tribal Nations in offshore wind energy decision-making. This initiative offers up to $7.1 million in cash prizes and technical assistance through three phases: Capacity Needs, Capacity Development, and Engagement. Each phase is designed to support Tribes in outlining their priorities, building capacity, and implementing impactful projects in offshore wind energy.

Community Foundation of the Holland/Zeeland Area

Our Mission

The Community Foundation of the Holland/Zeeland Area seeks to ensure that our community thrives today, tomorrow, and forever by building our Community’s Endowment to support high impact charitable projects, helping donors achieve their charitable goals, and leading and partnering in community-level initiatives.

Scholarships

CFHZ awards over $1 million in scholarships each year for students to attend schools of higher education throughout the nation. Our scholarships are possible thanks to the generosity of donors who invest in our community’s future by furthering the education of others.

All Holland/Zeeland area individuals interested in post-secondary education are encouraged to apply for CFHZ scholarships.

The Foundation proudly administers over 100 scholarships, each with unique eligibility criteria that must be met before a candidate can be considered.

Peter and Huberdina Weller Scholarship

• Graduating senior, graduating early college student, or current college student from a high school within the greater Community Foundation service area
• Enrolling/enrolled at an accredited post-secondary school within the United States
• Financial need (must submit the page of the FAFSA Submission Summary showing the Student Aid Index amount)
• GPA of 3.0 or greater
• Intention to pursue educational opportunities and a career in horticulture or the biological sciences with an emphasis on botany
• All other qualifications being equal, tie-breaking consideration will be given to students of color
• Previous recipients of the award are encouraged to reapply.

Investing in research and healthcare to prevent, treat, and heal firearm-related harms

Kaiser Permanente Center for Gun Violence Research and Education

Kaiser Permanente established this Center in 2022 to scale its longstanding commitment to help communities prevent, treat, and heal from firearm-related injuries or death. The Center’s focus on violence prevention is rooted in healthcare, care delivery, and clinical interventions.

The Center is coordinated in collaboration with the Health Alliance for Violence Intervention (HAVI).

Research to support more effective health interventions

The Center funds research to test and expand health interventions that treat and prevent firearm injuries and deaths. This approach uses the same rigor and expertise that has helped treat and prevent other leading health concerns and causes of death, such as stroke, cancer, and heart disease. Funding supports projects to:

• Identify and evaluate health system strategies to address firearm injury and death, especially in communities that are most impacted.
• Test clinical interventions to prevent, treat, and heal trauma caused by firearm injuries and death.
• Assess pathways to implement and scale clinical interventions for firearm injury prevention in various healthcare settings.
• Improve healthcare identification and engagement of individuals at high risk of firearm injury or death.

Since its inception, the Center has awarded more than $8.5 million through 49 grants across 25 states and Washington, D.C., to advance research, capacity building, narrative change, and education.

Funding Opportunity

The call is open to applicants at varying stages of the research continuum. It is expected that central to all proposed initiatives are efforts to meaningfully engage communities that have been the most impacted by firearm violence.

What Work Will Be Considered for Funding?

Funding is currently available in two categories: Category 1 - Research Capacity Building; Category 2 - Pilot or Formative Healthcare Research

Category 2 - Pilot or Formative Healthcare Research

Up to two (2) projects will be selected, each receiving up to $250,000 over two (2) years.

Expand or pilot new research on evidence-informed healthcare practice or clinical care models that address firearm violence or firearm suicide.

Steven Thayer Hopi Scholarship

This scholarship was established by the family of Steven Thayer to provide scholarship funding for young Hopi artists to develop their talents and artistic skill.

The Warren Alpert Foundation aims to enhance public health by funding medical research, education, and basic human services. With grants under $25,000, it supports initiatives that advance medical treatments and health education. The foundation is committed to fostering innovative research and solutions in healthcare, making a significant impact on community health and well-being.

Chautauqua Region Community Foundation

Mission: In partnership with our community, we ignite positive change and create a legacy of impact.

Scholarships

The Chautauqua Region Community Foundation annually awards more than $2 million in scholarships to students pursuing higher education, job training and certification. The Foundation hosts several different scholarship opportunities throughout the year. 

Space Camp Scholarship

Open to students (grades 4-12) or adults from Chautauqua County, NY or Warren County, PA to support the cost of attending U.S. Space Camp. 

The AWWA Scholarship Program, specifically the Neptune Technology Group Scholarship, offers a $5,000 award to undergraduate students pursuing degrees in mechanical, electrical, computer, or software engineering. This initiative, supported by the American Water Works Association, highlights the importance of investing in the future workforce of the water industry, fostering education and innovation among aspiring professionals.

The Louisville Institute offers the Grant for Researchers to support academic research in North American Christianity and related fields. Grants of up to $55,000 are available for sabbatical leaves, research projects, and necessary resources. This flexible program combines previous grants to meet contemporary academic needs. Applicants can apply individually or as teams of up to three, provided they are based in the U.S. or Canada. Projects bridging scholarship and church life are of particular interest.