Best Grants for Cancer Nonprofits in Illinois

Childhood Cancer Research

The grant purpose is to fund one awardee or a research project conducted by Illinois researchers on childhood cancer. The grant award must be used to research childhood cancers or expand current childhood cancer research that must be completed by June 30, 2027. Topics may include, but are not limited to, epidemiology, etiology, pathology, social or economic impacts, in-home care, and psychosocial issues. This is a one-year grant award.

Nonprofit 501(c) organizations in Illinois addressing health equity through nutrition, healthcare access, cancer care, STEM education, or environmental health programs can apply for the Community Solutions Challenge, with awards up to US $30,000. Grants from Astrazeneca Foundation help community-based programs serving historically excluded populations, including cancer-focused initiatives and related health disparities work.

Nonprofit and other public or private organizations in Illinois can apply for Illinois Department of Public Health’s Carolyn Adams Ticket for the Cure grants, awarding up to US $300,000 for breast cancer patient navigation and related services. Cancer-focused groups, especially those serving high-mortality counties like Cook, DuPage, Kane, Kankakee, Peoria, and St. Clair, may benefit.

Nonprofit organizations in the greater Chicago metropolitan area working on cancer care or research, education for the underprivileged, or related Catholic charitable activities can seek support through the Guy A. and N. Kay Arboit Charitable Trust. First American Bank administers this trust, which may benefit Illinois cancer nonprofits serving under-resourced communities.

Elderly professional blues musicians in the U.S. facing emergency medical or living expenses can receive $500 in direct creditor payments for care, transportation, utilities, or burial costs. Pinetop Perkins Foundation provides this support nationally, and Illinois artists dealing with cancer-related treatments or other serious health issues may be eligible.

Nonprofit and other eligible U.S. organizations conducting cancer/oncology comparative clinical effectiveness research can apply for up to US $13,000,000 to improve care across the cancer continuum, including in Illinois. With a mission to improve patient-centered outcomes, Patient-Centered Outcomes Research Institute supports projects on screening barriers, treatment delivery, and survivorship follow-up needs.

Illinois cancer and health research organizations can access funding through the Patient-Centered Outcomes Research Institute for retrospective observational comparative effectiveness studies using existing data. Eligible public and private sector entities, including IRS-recognized U.S. organizations, may request up to US $2,000,000 to study cancer or related priority topics and inform patient-centered healthcare decisions.

Cancer research institutions and academic medical centers conducting translational oncology studies in Illinois and nationwide can seek funding to advance organ-specific or biologically related human cancer research. National Institutes of Health SPORE P50 center grants provide US $25,000,000 to support clinical trial–required projects focused on prevention, early detection, diagnosis, and treatment of human cancers.

Graduating high school seniors and healthcare professionals pursuing oncology or hematology education in Central or Southern Illinois can receive tuition or professional development support, including certifications and conferences. Heart of Illinois Community Foundation’s Cancer Care Specialists of Illinois Scholarship serves residents of Macon, Moultrie, or Piatt County with a minimum 3.0 GPA; applications are reviewed monthly through December 1, 2025.

Full-time radiation oncology faculty at U.S. academic institutions or eligible nonprofits conducting cancer research can seek multi-year clinician-scientist career development support through this program, including those based in Illinois. Focused on cancer and radiation oncology, American Society for Radiation Oncology and American Cancer Society provide US $135,000 annually for 3–5 years to help clinicians become independent investigators.

Practicing radiation oncologists in Illinois and across the U.S. can apply for the ACS-ASTRO Felix Feng, MD Clinician Scientist Development Award, which provides US $729,000 for cancer research. This American Society for Radiation Oncology partnership supports clinician-scientists investigating questions across the cancer continuum, which may benefit hospital- or clinic-based cancer programs and nonprofit-affiliated researchers.

Incyte Corporation, a biopharmaceutical leader, offers healthcare sponsorships to support organizations focused on improving patient care and access to healthcare information. Eligible applicants include medical schools, associations, non-profits, advocacy groups, and hospitals. Requests should align with Incyte's commitment to enhancing the lives of patients affected by cancer and other diseases, ensuring compliance with regulatory guidelines. Organizations must enter a written agreement with Incyte to receive funding.

Incyte Corporation invites organizations to submit membership requests aimed at enhancing healthcare access for patients and advocates. As a biopharmaceutical leader, Incyte supports initiatives that align with its mission to improve patient lives through grants and contributions. Eligible entities include medical schools, associations, non-profits, and advocacy groups. Requests should comply with Incyte's regulatory standards and be submitted at least 60 days prior to the required decision date.

The 2026 Radiation Oncology Institute- Innovation Awards aim to advance cancer treatment by integrating radiation therapy with immunotherapy. Researchers are invited to submit proposals that explore optimal combinations of these modalities to enhance patient outcomes. Funding of up to $100,000 over two years will support projects focused on identifying effective treatment strategies, understanding mechanisms of synergy, and improving access to care. This initiative represents a significant opportunity for innovative research in oncology.

The Radiation Oncology Institute (ROI) Innovation Awards, offered by the American Society for Radiation Oncology, aim to accelerate innovative ideas in radiation therapy. Currently accepting applications for the 2026 awards, the program focuses on optimizing the combination of radiation therapy and immunotherapy to enhance cancer treatment outcomes. By supporting practical research, ROI strives to transform clinical practices and improve patient care in the fight against cancer.

Pfizer is offering a grant opportunity for independent medical education initiatives focused on Muscle Invasive Bladder Cancer (MIBC). This program aims to address the current knowledge gaps among healthcare professionals regarding emerging treatment data and its potential impact on clinical practices. By collaborating with Astellas, Pfizer seeks proposals that enhance awareness and understanding of the evolving MIBC landscape, ultimately improving patient outcomes in this critical area of unmet medical need.

The Joyce Bytof Memorial Cancer Survivors Scholarship, established by Joyce Bytof in collaboration with the American Cancer Society, supports childhood cancer survivors graduating from specific Wisconsin high schools. This scholarship aims to assist them in pursuing higher education despite the financial and academic challenges posed by their experiences. Joyce's legacy continues to inspire hope and resilience among young survivors as they strive for academic success and a brighter future.

The AACR-Torrey Coast Foundation Transpacific Gastric and Esophageal Cancer Research Partnership Grant supports innovative research on upper gastrointestinal malignancies, which are responsible for over one million deaths globally in 2023. This grant encourages collaboration between U.S. and Asian institutions, focusing on resistance, metastasis, and novel treatment strategies. Proposals should detail plans for clinical translation and are open to researchers at all career stages, especially those new to upper GI cancer research.

Bristol Myers Squibb Foundation Inc supports independent medical education to enhance healthcare professional competence and improve patient health outcomes. Their mission is to be a global leader in innovative medical education, focusing on evidence-based activities that address critical gaps in knowledge. By fostering excellence in healthcare, they aim to ensure measurable improvements in performance and patient outcomes across various disease areas.

The National Cancer Institute (NCI) invites applications for the validation of biomarkers and assays for cancer detection and treatment. This funding opportunity allows for biphasic or monophasic applications to support both analytical and clinical validation phases. Successful projects will leverage human specimens to develop assays that enhance cancer treatment and prevention, ensuring multidisciplinary collaboration among scientists and clinicians. This initiative aims to improve cancer management through reliable and clinically validated tools.

The American Heart Association is seeking proposals to study the prevalence and treatment of cardiovascular, kidney, and metabolic diseases among cancer patients and survivors. Given the over 16.7 million cancer survivors in the U.S., this research aims to highlight critical health disparities, identify treatment modalities, and explore shared risk factors. Applications focusing on underrepresented populations and utilizing real-world data sources are especially encouraged, aiming to improve health outcomes in this vulnerable group.

The ASCO Clinical Oncology & Research Experience (ASCO CORE) offers medical students immersive exposure to the field of oncology through shadowing experiences in clinical and research settings. With two distinct tracks, participants can gain insights into patient care or research practices, guided by mentors. Eligible students must be enrolled in a U.S. DO or MD program and maintain a good academic record. This program aims to inspire the next generation of oncology professionals.

Grants Program for Penn Investigators - Faculty Awards

Research grant applications in basic science, prevention, disease interception, and early detection that are relevant to the study of BRCA1/2 will be considered. The Basser Cancer Interception Institute focuses on funding new endeavors in emerging, orthogonal fields beyond DNA damage (e.g. mechanisms of haploinsufficiency, cancer evolution and tissue tropism). 

Grants focused on the following are of particular interest:

• Cancer interception and the pre-cancer disease state
• Issues relevant to men (including but not limited to prostate cancer, pancreatic cancer, male breast cancer)
• Potential for translation into clinical practice
• Early detection

Grants that demonstrate a potential for translation into clinical practice will be prioritized for funding.

Faculty Awards

Faculty awards are for two years with a funding level up to $200,000 per year.

Grants Program for Penn Investigators - Early career awards for Fellows, Postdocs and Instructors

Research grant applications in basic science, prevention, disease interception, and early detection that are relevant to the study of BRCA1/2 will be considered. The Basser Cancer Interception Institute focuses on funding new endeavors in emerging, orthogonal fields beyond DNA damage (e.g. mechanisms of haploinsufficiency, cancer evolution and tissue tropism). 

Grants focused on the following are of particular interest:

• Cancer interception and the pre-cancer disease state
• Issues relevant to men (including but not limited to prostate cancer, pancreatic cancer, male breast cancer)
• Potential for translation into clinical practice
• Early detection

Grants that demonstrate a potential for translation into clinical practice will be prioritized for funding.

Early career awards for Fellows, Postdocs and Instructors

Early career awards for Fellows, Postdocs and Instructors up to $100,000 for one year. Grants are eligible for competitive renewal upon reapplication and are contingent on progress the first year.

The CORE Funding: AHNS Presidential Award supports innovative research that integrates emerging technologies in head and neck cancer studies. This initiative aims to address critical gaps in early detection and treatment, especially for patients with advanced disease. By leveraging tools such as AI and advanced imaging, the program seeks to enhance understanding of disease mechanisms and improve patient-centered intervention strategies, ultimately advancing the field of otolaryngology.

The CORE Funding: AHNS Thyroid Cancer Survivors’ Association Award aims to support vital research projects focused on thyroid cancer, encompassing prevention, diagnosis, treatment, and outcomes. This initiative by the American Academy of Otolaryngology - Head and Neck Surgery Foundation promotes advancements in the field through funding opportunities that enhance research capabilities and foster collaboration among researchers. Through the support of this award, significant strides can be made in understanding and combating thyroid cancer.

Improving Metastatic Prostate Cancer (mPCa) Care Through Innovative Strategies

The National Comprehensive Cancer Network® and Pfizer Global Medical Grants (Pfizer) are collaborating to offer a new grant opportunity seeking proposals for investigator-initiated research to improve mPCa care. Pfizer (hereafter, “Grantor”) is providing $1 Million in funding to support quality improvement studies to advance health care quality, the delivery of quality care, and improve health care provider performance in mPCa care. The Grantor will serve as the funding organization. Grants are available to all investigators from institutions within the United States. 

Aim

To promote the advancement of scientific knowledge, health care provider performance, and/or health care quality improvement focused on improving mPCa care.

A total of $1 Million is available to fund all projects. The intent is to fund 2-5 studies. There is a funding cap of $250,000 per study. Exceptional studies with budgets above this amount will be considered based on scientific merit and must contain a robust justification. All budgets must include line-item information and robust justification.