Best Grants for Nonprofit Healthcare Programs in Illinois

CommonSpirit Health offers the Community Health Improvement Grant to enhance health equity and service systems for underserved populations. Through collaborative efforts with 501(c)(3) organizations, this initiative provides financial support for essential health projects. Grant amounts range from $19,500 for small grants to $150,000 for standard grants, varying by hospital. Participating hospitals include those under Catholic Health Initiatives and Dignity Health, aimed at addressing significant community health needs.

The Cleveland-Cliffs Foundation, established in 1962, focuses on enhancing educational opportunities, environmental protection, and community health in the regions it operates. As a leading steel manufacturer, Cleveland-Cliffs is committed to sustainability and responsible corporate citizenship. The foundation supports 501(c)(3) organizations that address key challenges in education, the environment, and community well-being, ensuring impactful investments that help communities thrive across North America.

The L.B. Research and Education Foundation Grant Program supports U.S.-based nonprofits focusing on innovative education and health solutions for underserved populations. Eligible organizations can apply by submitting a 400-word concept paper, and selected applicants may receive funding ranging from $10,000 to $75,000. The Foundation prioritizes projects that foster critical thinking and creativity, address health disparities, and encourage collaboration. There are no application deadlines, promoting year-round engagement.

The FY26 Rural Support Grant aims to enhance the quality of life for older adults in rural Illinois by addressing specific challenges such as transportation, technology access, and volunteer recruitment. Organizations eligible for funding must be designated Area Agencies on Aging and comply with various requirements. The grant focuses on initiatives that reduce social isolation, improve health outcomes, and strengthen community connections. This funding opportunity promotes sustainable solutions through capacity building and partnership engagement.

The Carolyn Adams Ticket for the Cure Grant supports organizations in Illinois to enhance patient navigation services for breast cancer. By addressing barriers to care, this initiative promotes timely diagnosis and treatment, ultimately improving outcomes for underserved communities. Funding will be allocated to programs that provide culturally competent education and link individuals to critical screening and prevention services. The grant aims to develop infrastructure that fosters equitable access to breast cancer care and support for survivors.

The Carolyn Adams Ticket for the Cure Community Outreach Grant aims to enhance breast cancer awareness and education through outreach programs in Illinois. Funded by the Illinois Department of Public Health, this initiative supports organizations conducting activities to promote equity in breast cancer outcomes, focusing on underserved populations. Key goals include increasing knowledge about breast health and facilitating access to screening and support services, ultimately improving health outcomes for women and men affected by breast cancer.

Community Health Center Construction Grants - Rebuild Illinois

Pursuant to 30 ILCS 766, the Community Health Center Construction Act ("Act"), the Capital Development Board ("CDB") (in cooperation with the Illinois Department of Public Health) is authorized to make grants available to Federally Qualified Health Centers (FQHC) and FQHC Look-Alikes which serve, in whole or in part, a designated Medically Underserved Area (“MUA”) or Medically Underserved Population (“MUP”) both as defined in the Act, for health center construction projects.

FNBO: Capital or Major Donations aims to support nonprofit organizations through significant financial contributions for capital projects. This initiative focuses on enhancing community well-being by addressing key areas such as affordable housing, environmental stability, and education. FNBO prioritizes partnerships with nonprofits dedicated to long-term impacts, especially for historically underrepresented populations. By fostering community engagement and providing essential resources, FNBO strives to create a positive influence in the regions it serves.

The Carolyn L. Kuckein Student Research Fellowship, awarded by Alpha Omega Alpha Honor Medical Society, supports first and second-year medical students conducting research over 2 to 12 months. With a total funding of $7,000, students can receive reimbursement for travel expenses up to $1,000 for presenting their findings at national conferences. Eligibility requires enrollment in schools with active AΩA chapters, while those taking a year off for research or holding a PhD are ineligible.

The Community Network Anchors RFA aims to strengthen existing Community Networks by fostering collaboration among diverse partners, including mental health providers, schools, and advocacy groups. This initiative is designed to enhance the well-being of families, helping them access essential resources to thrive and mitigate crises. Grant recipients will build on existing materials provided by IDPH and CBHTI, engaging in regular meetings to ensure a robust support system in their communities.

The James M. Cox Foundation Grant offers support to nonprofit organizations focused on conservation, early childhood education, family empowerment, and health. Organizations must be 501(c)(3) tax-exempt and located in areas where Cox Enterprises operates. Grant applications are accepted year-round, with deadlines before Trustee meetings. Preference is given to organizations with a history of local engagement. This foundation embodies the philanthropic spirit of its founder, James M. Cox, by giving back to the community.

The Illinois Racing Board Charity Grant provides essential Wellness Services to individuals working or residing at Illinois' pari-mutuel race tracks. With over $26 million allocated over 30 years, the program ensures access to medical, dental, and counseling services. For 2024, approximately $767,193 is available for grants, supporting non-profit organizations that can demonstrate a commitment to the well-being of backstretch residents. Eligible applicants must meet specific requirements, including prior IRS approval and a solid project plan.

FNBO's Community Sponsorships provide vital financial support to nonprofit organizations and community events that enhance the well-being of our communities. By focusing on affordable housing, entrepreneurship, education, environmental sustainability, access to arts and culture, community cohesion, and health, FNBO aims to create impactful partnerships. Monthly reviews of sponsorship requests ensure timely decision-making, emphasizing FNBO's commitment to fostering community development and empowering historically underrepresented populations.

The Great Lakes Federal Grant Navigation Program offers free assistance to local governments in accessing critical federal funding from the American Rescue Plan Act and the Infrastructure Investment and Jobs Act. This program aims to simplify the grant application process, especially for smaller municipalities, by providing one-on-one support and facilitating collaboration among cohort members. By participating, cities can maximize the impact of federal dollars and strengthen their communities in the wake of economic challenges.

The Frankenmuth Insurance Foundation Charitable Grant supports qualified charities focused on community betterment and basic human needs. Founded in 2016, it aims to enhance lives through initiatives such as affordable housing, health programs, and the arts. Organizations eligible for funding must be tax-exempt and serve areas where Frankenmuth Insurance operates. Notably, the foundation excludes support for individuals, political groups, and projects typically financed by governments, ensuring its resources benefit the wider community.

About CommonSpirit

A calling that defines and unites

At CommonSpirit Health, we passionately care for the most vulnerable, relentlessly innovate how and where healing can happen and believe in uniting to benefit the common good. Our expansive network spans diverse communities, uniquely positioning us to meet their changing needs, improve population health and help chart the path to health equity.

Our mission, vision and values inform every aspect of our work each day and remind us that we serve our patients, their families, our communities – and each other. Our community health, research and home health programs help us address the primary barriers to healthier communities.

Sponsorship requests

We’re proud to support nonprofits that expand access to care, advance health equity and healthier communities. Learn more about our priorities.

Supporting our communities

CommonSpirit Health and our local facilities support nonprofit organizations that share our mission, vision and values. We give priority to programs that improve access to care and promote health equity and healthier communities.

CommonSpirit is proud to support nonprofit organizations that help improve the health and well-being of our communities. Guided by our mission, vision and values, we prioritize projects that focus on advancing health equity, improving access to care and improving community wellness.

The ACT on Health Equity Community Solutions Challenge Grant, backed by the Astrazeneca Foundation, aims to enhance health equity by funding community-based nonprofit programs. Since its inception in 2021, it has allocated over $2.6 million to initiatives addressing nutrition, healthcare access, and lung health for historically marginalized populations. Eligible US-based 501(c) organizations can apply, with a focus on projects serving underserved communities and improving health outcomes through targeted support.

At Genentech, we invest in bold ideas and innovative solutions that address systemic inequities in science and medicine to advance a more just healthcare system. We focus on efforts that diversify the scientific and medical workforce, advance health equity, and help our communities thrive. We also further advance excellence in medicine and healthcare through our grants for independent medical education. Including efforts to advance health equity, support patient needs, engage the scientific community, and provide co-pay assistance. 

There are multiple ways to apply for funding. Before you submit an application, we encourage you to explore the following materials to learn more about our opportunities for funding, eligibility requirements and considerations, and the process for submitting a proposal within our Funding Request System (gFRS).

The GoodRx Helps Community Catalyst Grants support community-led nonprofits dedicated to enhancing health and well-being for under-resourced groups. This funding aims to improve healthcare access, education, and essential services, addressing systemic barriers faced by these communities. Eligible organizations must demonstrate a commitment to community empowerment and possess a minimum annual operating budget of $250K. This initiative underscores the importance of fostering sustainable health improvements through targeted, inclusive support.

Overview

The Lake County Community Foundation asserts that the quality of life of Lake County can be improved through an earnest effort to bring organizations, government, businesses, corporations and civic leaders together to establish a common vision, adopt a shared set of measurable goals and pursue evidence-based activities that reinforce one another’s objectives as a means of addressing the most pressing needs of our community.

The Foundation envisions a county-wide health and human services delivery system that is robust and thriving with a network of providers capable of achieving the greatest impact on the urgent needs of the most vulnerable residents of the county.

The Foundation’s approach combines strategic community leadership with intentional organizational investment—ultimately leading to a more streamlined coordination of countywide efforts.

Nonprofit Capacity Building Priority Area Grants

The Lake County Community Foundation (LCCF) is relaunching its Capacity Building priority area for Spring 2026 to support nonprofits in strengthening their internal operations and organizational effectiveness. This funding is designed to enhance nonprofit sustainability, efficiency, and long-term growth so organizations are better equipped to serve the community. Capacity Building grants support one-time organizational costs and expenses; recurring salaries, fees, or ongoing operational costs are not eligible. Organizations that receive a Capacity Building grant may still apply for and receive funding under LCCF’s Growing Communities priority area, as participation in one does not preclude funding from the other.

Overview

The Lake County Community Foundation asserts that the quality of life of Lake County can be improved through an earnest effort to bring organizations, government, businesses, corporations and civic leaders together to establish a common vision, adopt a shared set of measurable goals and pursue evidence-based activities that reinforce one another’s objectives as a means of addressing the most pressing needs of our community.

The Foundation envisions a county-wide health and human services delivery system that is robust and thriving with a network of providers capable of achieving the greatest impact on the urgent needs of the most vulnerable residents of the county.

The Foundation’s approach combines strategic community leadership with intentional organizational investment—ultimately leading to a more streamlined coordination of countywide efforts.

Early Childhood Education Priority Area Grants

The Lake County Early Childhood Education Fund provides grant support to organizations serving children from prenatal through age five in Lake County. Established in 2010, this restricted fund is dedicated to strengthening and expanding early childhood education opportunities across the county. There is no letter of inquiry requirement; eligible organizations are invited to apply directly. Funding priority is given to projects that introduce new and innovative approaches to early childhood education, reduce barriers to access for Lake County residents, and address otherwise unmet needs, particularly in areas where the applicant is the sole service provider.

Overview

The Lake County Community Foundation asserts that the quality of life of Lake County can be improved through an earnest effort to bring organizations, government, businesses, corporations and civic leaders together to establish a common vision, adopt a shared set of measurable goals and pursue evidence-based activities that reinforce one another’s objectives as a means of addressing the most pressing needs of our community.

The Foundation envisions a county-wide health and human services delivery system that is robust and thriving with a network of providers capable of achieving the greatest impact on the urgent needs of the most vulnerable residents of the county.

The Foundation’s approach combines strategic community leadership with intentional organizational investment—ultimately leading to a more streamlined coordination of countywide efforts.

Growing Communities Priority Area

Two-Year Grants support nonprofit organizations in achieving strategic growth, program stability, and long-term planning by providing greater financial predictability and strengthening organizational capacity for deeper community impact. Funding prioritizes initiatives that promote equitable access in Lake County to affordable nutritious food, comprehensive health care including mental health services, safe and affordable housing, education and workforce opportunities, and immigration and legal support services. Preference is given to grassroots, community-based organizations that address barriers to accessing essential services and benefits, and to organizations serving unmet basic needs as the sole provider in their area.

NM Community Impact Donations

Introduction

Northwestern Medicine provides financial support to designated nonprofit organizations and governmental and public entities that are working to address identified community health priorities. Many needs are determined during each hospital’s Community Health Needs Assessment, which is conducted every three years. View a list of priority health needs for each hospital.

The Excellence in Medicine Awards, presented by the AMA Foundation, honor exemplary physicians and medical advocates committed to volunteerism, community engagement, and leadership. Since 2005, this prestigious program has celebrated over 100 honorees, recognizing their vital contributions to underserved populations. Awardees receive a $2,500 grant honorarium to support a nonprofit health organization of their choice, collectively awarding over $250,000 to enhance community health and promote equitable care across the nation.

The NIHCM Foundation's Television and Audio Journalism Award honors outstanding television and audio reporting that contributes to enhancing the affordability, accessibility, and quality of healthcare in the U.S. With a prize of $20,000, the award seeks entries that showcase creativity and originality while providing new insights relevant to health plans, policymakers, and consumers. Eligible entries include stories broadcasted in 2025, focusing on critical healthcare issues.

Mission

To empower worthy nonprofits by providing critically needed, unrestricted funding that helps them fulfill their missions with confidence and sustainability.

How We Serve Nonprofits

AmFund partners with nearly 800 organizations annually—supporting causes related to health, education, the arts, human services, animal welfare, and more. We’re known for our:

• Signature silent and live auctions featuring once-in-a-lifetime travel experiences.
• National reach with personalized service at events in all 50 states.
• Comprehensive marketing toolkits, onsite staff support, and beautifully displayed materials
• No-cost platform development for virtual and hybrid fundraising
• In-house travel specialists who provide custom planning, extensions, insurance, and 24/7 emergency support.
• Ongoing educational resources, grants, and consulting support for nonprofit development.

Request Support

Our model is built on relationship, trust, and results. Every trip sold, every service provided, and every donor interaction is designed to maximize your fundraising impact—without adding burden to your team.

Home

The Middle Run Foundation is a family-governed foundation based in Newark, Delaware. The Board of the foundation is chaired by Sarah Ives Gore, its founder, and includes her children, grandchildren, and non-family members who bring experience and expertise to our work.

About

Purpose:

The purpose of the foundation is to fund and support non-profit programs which focus on building healthy, self-sufficient families.

Apply

The Middle Run Foundation makes grants up to $500,000 annually with individual grants ranging from $5,000 to $50,000.