Best Large Grants for Nonprofit Organizations in Tennessee

The St. Baldrick’s Foundation Research Grant Award supports innovative research aimed at curing childhood cancers. With funding of $100,000 per year for two years, this grant is designed for hypothesis-driven projects that can be laboratory, clinical, or epidemiological in nature. Established through community-driven fundraising events, the foundation empowers volunteers and donors to make a significant impact in the fight against cancer, ensuring a brighter future for young survivors.

The Spotlight Fund Grants aim to enhance racial equity in K-12 education by providing flexible funding to BIPOC educators. With grants ranging from $500 to $1,000 per educator, these funds are essential for sourcing tools and materials that support diverse student needs. As schools face budget cuts exacerbated by COVID-19, this initiative focuses on proven strategies that foster an inclusive learning environment for students of color, ensuring they have equal opportunities to thrive.

The Kidney Precision Medicine Project (KPMP), funded by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), aims to enhance research on Chronic Kidney Diseases (CKDs) and Acute Kidney Injuries (AKIs). Launched in 2017, this initiative focuses on ethical collection and analysis of human kidney tissue to uncover new molecular pathways. With expanded participant recruitment efforts beginning in 2022, the KPMP seeks to advance our understanding of kidney-related health issues.

The Incubator Grant, offered by the Society of Interventional Radiology Foundation, supports projects that enhance interventional radiology through clinical research. Eligible applicants must be SIR members and hold relevant degrees. The grant provides funding up to $25,000 for one year, specifically for developing clinical study protocols and proposals. This initiative emphasizes inclusivity and encourages innovative approaches in patient care, aligning with the foundation's mission to advance the specialty and improve patient outcomes.

The National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) is extending the Kidney Precision Medicine Project (KPMP) for five years to enhance participant recruitment and tissue interrogation. This initiative aims to discover novel molecular pathways associated with Chronic Kidney Diseases (CKDs) and Acute Kidney Injuries (AKIs). The renewed funding will support robust longitudinal follow-ups for existing enrollees and facilitate the enrollment of new participants, ensuring comprehensive data analysis and collaboration within the research community.

The Kidney Precision Medicine Project Central Hub, funded by the National Institute of Diabetes and Digestive and Kidney Disease (NIDDK), aims to enhance our understanding of Chronic Kidney Diseases (CKDs) and Acute Kidney Injuries (AKIs). This initiative, which began in FY2017, focuses on ethically collecting and analyzing kidney biopsy tissues to uncover molecular pathways. The project was expanded in FY2022 to improve participant recruitment and tissue analysis, driving forward research in kidney health.

The Biocodex Microbiota Foundation invites early career researchers in the microbiome field from U.S. institutions to apply for the 2024 grant. This initiative focuses on groundbreaking research into gut microbiota's role in human health and disease, particularly in areas like circadian rhythms and metabolic disorders. The grant supports operational costs, allowing for innovative projects aimed at fostering independent research careers in microbiota studies.

The Raskob Foundation offers domestic grants to organizations located in the U.S. and its territories. Founded in 1945, this private, non-profit foundation focuses on supporting Catholic institutions. Eligible applicants must be tax-exempt 501(c)(3) organizations, listed in the P.J. Kenedy Official Catholic Directory. However, requests from individuals and certain projects, such as debt reduction or completed projects, are not accepted. The foundation emphasizes its commitment to philanthropy and community support.

The National Multiple Sclerosis Society offers Postdoctoral Fellowships to support innovative research aimed at advancing the understanding and treatment of multiple sclerosis. These fellowships are designed for promising researchers holding advanced degrees, providing funding for training that enhances their ability to conduct impactful studies. The Society prioritizes applications that align with high-priority research questions outlined in its Pathways to Cures Roadmap, emphasizing the importance of diverse methodologies and engagement with underserved populations.

Grand Traverse Regional Community Foundation

The Grand Traverse Regional Community Foundation began in 1992 when a group of community champions came together around a vision to give back to our region then, now, and forever.

This vision lives on within our organization today as we support the people and places of Antrim, Benzie, Grand Traverse, Kalkaska, and Leelanau Counties and the Grand Traverse Band of Ottawa & Chippewa Indians.

Together with our partners, we spark positive change for a variety of local causes, including youth, arts and culture, education, environment, and health and human services, across our region.

Traverse City Area Public Schools (TCAPS) Scholarships

The Community Foundation is home to a variety of scholarships designated to benefit a graduating senior from Traverse City Area Public Schools (TCAPS). 

The Les and Anne Biederman Foundation, Inc. Scholarship Fund (Central, West)

In keeping with the visions and determinations that were held by the late Les Biederman, this scholarship is available to students who endeavor to pursue careers in nursing or business.

One scholarship awarded annually at each Central and West for a student pursuing a career in business and one scholarship awarded annually at each Central and West for a student pursuing a career in nursing.

The Frederic C. Collin Trust Grant supports 501(c)(3) organizations in promoting polo and tennis, especially among youth. Established under Frederic C. Collin's will, it offers grants ranging from $2,000 to $3,800, with an annual total giving of approximately $9,000. Applications are accepted year-round for consideration during the annual grant meeting. This initiative aims to enhance participation in these sports, fostering talent and interest among young players.

The Minnesota Ovarian Cancer Alliance (MOCA) is offering grants for research focused on the early detection of ovarian cancer. With funding amounts of either $50,000 or $100,000 available, these grants support projects aimed at enhancing prevention strategies. Eligible applicants include U.S.-based researchers outside of Minnesota, and the awards will be distributed in November 2025. This initiative aims to foster innovative approaches to combat ovarian cancer effectively.

The Anna Fuller Fund Grant provides year-round support for organizations dedicated to alleviating suffering caused by cancer. Established in memory of Egbert C. Fuller’s wife, the fund prioritizes applications that focus on cancer research and education initiatives. Eligible applicants must be 501(c)(3) organizations or equivalent charities outside the U.S. Grant funds cannot be used for direct treatment, ensuring that resources are allocated to research and public education.

The Disability Inclusion Fund Grant, managed by Borealis Philanthropy, aims to support organizations advocating for disability inclusion, rights, and justice. As a partner in philanthropy, Borealis facilitates donor collaboratives to maximize impact across various communities and movements. Organizations interested in applying for this grant are encouraged to review the detailed FAQ for further information. This initiative is a vital step towards fostering inclusivity and promoting the rights of individuals with disabilities.

The Craft Artists Emergency Relief Grant provides $3,000 to U.S.-based individual craft artists aged 18 and older who are facing recent, unforeseen emergencies. Established by the Craft Emergency Relief Fund (CERF+) in 1985, this grant aims to empower artists during critical times, allowing them to use the funds as needed for recovery. Applications are accepted on a rolling basis, ensuring timely support for artists in distress.

The CERF: Artist Get Ready Grant offers up to $1,000 to craft artists for safeguarding their studios and preparing for emergencies. Priority is given to underrepresented artists, including BIPOC and folk/traditional artists. Eligible activities encompass studio safety upgrades and disaster readiness. Applicants must be 18 years or older, residing in the U.S. for two years, and not have received this grant in the previous year. Funds must be used within six months, with outcomes documented for CERF+.

The NIMH Career Transition Award (K22) supports tenure-track intramural investigators at NIMH in their transition to independent research faculty positions. This program aims to foster innovative research in mental health, encouraging applicants with a strong record of research excellence. Key deadlines for applications vary, including those for standard and renewal submissions, emphasizing the importance of timely applications to secure funding and advance mental health research initiatives.

Devinci's Community Grant Program aims to support North American cycling organizations with financial assistance for development projects. Eligible applicants include cycling clubs, non-profits, and individuals leading community initiatives. Projects must occur in Canada or the U.S. within the year, with a maximum grant of $5,000 CAD. The program collaborates with key industry partners to foster growth in the cycling community, making a lasting impact through local initiatives.

The ChemClub Student Scholarship, offered by the American Chemical Society and the American Association of Chemistry Teachers, supports high school seniors who are active members of a Chartered ChemClub. Eligible students must demonstrate academic excellence and express their commitment to STEM fields. This scholarship provides financial assistance directly to the recipient's chosen college, fostering future leaders in chemistry and related disciplines.

The Parkinson Association of the Rockies Eric Wright Memorial Fund honors Eric Wright's legacy by providing scholarships to high school seniors and college students affected by Parkinson Disease. Recipients, eligible for up to $20,000 over four years, are selected based on merit and financial need. This fund aims to inspire the next generation while supporting students who have experienced loss or hardship due to this condition, promoting education and resilience within the community.

The CLRA Research Grant Program, led by the Children’s Leukemia Research Association, focuses on funding innovative research aimed at uncovering the causes of leukemia and improving treatment options. Grants totaling $30,000 are awarded to U.S.-based researchers, with the intention of advancing scientific understanding and ultimately finding a cure. The program has made significant contributions to the high cure rates for childhood leukemia, showcasing the importance of continued research in this field.

The AGA-Gastric Cancer Foundation Ben Feinstein Memorial Research Scholar Award provides $100,000 annually for three years to early-career faculty dedicated to gastric cancer research. Eligible candidates must have an MD, PhD, or equivalent and a full-time faculty position in North America. The award supports research in various areas related to gastric cancer, ensuring a minimum of 50% time commitment to the project, thus fostering independent careers in digestive diseases.

The American Diabetes Association's Postdoctoral Fellowship Awards aim to foster emerging leaders in diabetes research. With a focus on innovative research, these fellowships provide up to three years of funding, including a stipend and allowances. Eligible applicants must hold a recent advanced degree and conduct research at U.S. affiliated institutions. This initiative not only supports career development but also contributes significantly to the mission of preventing and curing diabetes.

Joseph G Markoly Foundation Inc

When Joseph Markoly originally established the foundation more than thirty years ago, its focus was on Alzheimer’s and heart disease support, funded through a number of the larger national disease-related organizations. Over time the focus has shifted to helping small to mid-size organizations in our local communities which support children and seniors in a variety of effective ways. 

Markoly Foundation was established in honor of Joseph G. Markoly, an entrepreneur and philanthropist who wanted to make a positive impact in people’s lives. Joseph’s family was affected directly by both Alzheimer’s and heart disease having lost a family member to each condition. For that reason, the foundation dedicates a majority of their resources to providing grants to organizations that focus on the treatment of each of these diseases. In addition, Markoly Foundation supports a variety of programs dedicated to helping children and seniors by providing services, supplies, programs and research in areas impacting these demographics.

Joseph G. Markoly Foundation Grant Support for Children’s Organizations

Children are the future of this world and the Markoly Foundation is proud to fund local programs dedicated to improving the lives of children and their families. From providing vision services for school kids to classes on parenting, we are proud to do our part to help fund critical community programs for families.

We are dedicated to providing funding for local nonprofit programs that improve the quality of life for all, but particularly for the children and elders in our community.

The Charlene (Charlie) Jane Toomey Memorial Scholarship Fund, established by the Community Foundation of Middle Tennessee, honors the legacy of a beloved community member dedicated to education and empowerment. This scholarship aims to support college-bound female students from 40 counties in the region, prioritizing those with a minimum 3.0 GPA and a commitment to extracurricular and community involvement. Through this initiative, we celebrate Charlie's belief in the transformative power of education and her enduring impact on future generations.

The Risk and Protective Factors of Family Health initiative invites research proposals to explore family health and resilience, addressing health disparities in minority communities. Key submission deadlines are set for various dates from February 2025 to February 2027. This program is supported by the National Institutes of Health, highlighting the importance of family well-being as a critical area for advancing health equity. Proposals should focus on interventions that improve family health outcomes.